Page last updated: 2024-11-01

nitrendipine and Hypotension

nitrendipine has been researched along with Hypotension in 4 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"The introduction of phosphodiesterase-5 inhibitors as sildenafil, tadalafil, or vardenafil, has tremendously improved the treatment of erectile dysfunction."9.13Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition. ( Jung, F; Leithäuser, B; Park, JW, 2008)
"The introduction of phosphodiesterase-5 inhibitors as sildenafil, tadalafil, or vardenafil, has tremendously improved the treatment of erectile dysfunction."5.13Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition. ( Jung, F; Leithäuser, B; Park, JW, 2008)
" In the present studies various doses of nitrendipine which is a new derivative of nifedipine were compared for their potencies to affect the blood pressure and heart rate, as well as the effect of drug-induced hypotension at the monoamine level in the spontaneously hypertensive rat (SHR) brain areas."3.67The relationship between calcium antagonist-induced hypotension and central monoaminergic system in spontaneously hypertensive rats. ( Hong, YL, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, JW1
Leithäuser, B1
Jung, F1
Parry, MJ1
Alabaster, VA1
Cheeseman, HE1
Cooper, K1
deSouza, RN1
Keir, RF1
Yasky, J1
Ferrario, CM1
Hong, YL1

Trials

2 trials available for nitrendipine and Hypotension

ArticleYear
Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition.
    Clinical hemorheology and microcirculation, 2008, Volume: 39, Issue:1-4

    Topics: Administration, Sublingual; Adult; Angina Pectoris; Blood Pressure; Carbolines; Cardiovascular Disea

2008
Nocturnal hypotension and ACE inhibitors.
    Journal of human hypertension, 1993, Volume: 7, Issue:3

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Circadian Rhythm; Enalapril; Female

1993

Other Studies

2 other studies available for nitrendipine and Hypotension

ArticleYear
Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity.
    Journal of lipid mediators and cell signalling, 1994, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Aorta; Azepines; Blood Platelets; Brain; Calcium Channels, L-Type; Ca

1994
The relationship between calcium antagonist-induced hypotension and central monoaminergic system in spontaneously hypertensive rats.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:11

    Topics: Adrenal Medulla; Animals; Blood Pressure; Brain; Chemical Phenomena; Chemistry; Dopamine; Femoral Ar

1987