Page last updated: 2024-11-01

nitrendipine and Gingival Hyperplasia

nitrendipine has been researched along with Gingival Hyperplasia in 3 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Gingival Hyperplasia: Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)

Research Excerpts

ExcerptRelevanceReference
"Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia."5.28Nitrendipine-induced gingival hyperplasia. First case report. ( Bottomley, WK; Brown, RS; Corio, R; Sein, P, 1990)
" The relative amounts of extracellular matrix macromolecules observed in 12 cases of gingival hyperplasia associated with the use of cyclosporin, hydantoin or nifedipine were compared with those obtained in a control group on the basis of histological and immunohistochemical investigations."3.69Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth. ( Bonnaure-Mallet, M; Godeau, GJ; Tricot-Doleux, S, 1995)
"Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia."1.28Nitrendipine-induced gingival hyperplasia. First case report. ( Bottomley, WK; Brown, RS; Corio, R; Sein, P, 1990)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bonnaure-Mallet, M1
Tricot-Doleux, S1
Godeau, GJ1
Brown, RS1
Sein, P1
Corio, R1
Bottomley, WK1
Heijl, L1
Sundin, Y1

Other Studies

3 other studies available for nitrendipine and Gingival Hyperplasia

ArticleYear
Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth.
    Archives of oral biology, 1995, Volume: 40, Issue:5

    Topics: Collagen; Cyclosporine; Elastic Tissue; Elastin; Extracellular Matrix; Extracellular Matrix Proteins

1995
Nitrendipine-induced gingival hyperplasia. First case report.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 70, Issue:5

    Topics: Aged; Enzyme Activation; Folic Acid Deficiency; Gingival Hyperplasia; Humans; Hypertension; Male; Ni

1990
Nitrendipine-induced gingival overgrowth in dogs.
    Journal of periodontology, 1989, Volume: 60, Issue:2

    Topics: Animals; Cohort Studies; Connective Tissue; Dental Plaque Index; Dogs; Epithelium; Fibroblasts; Ging

1989