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nitrendipine and Diabetes Mellitus, Adult-Onset

nitrendipine has been researched along with Diabetes Mellitus, Adult-Onset in 20 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"A trial to study the efficacy, safety and tolerability of nitrendipine and enalapril in the treatment of diabetic hypertensive patients with microalbuminuria (MA) was performed to compare the effects of both drugs in the prevention of the renal impairment."9.08Nitrendipine and enalapril in the treatment of diabetic hypertensive patients with microalbuminuria. ( Cases, A; Closas, J; Cobos, A; Esmatges, E; Pascual, R; Piñol, C; Planas, J; Soler, J, 1996)
"To compare the effects of a calcium antagonist (nitrendipine) and an angiotensin converting enzyme inhibitor (enalapril) with those of placebo on left ventricular mass in patients with non-insulin-dependent diabetes mellitus and hypertension."9.08Effects of nitrendipine and enalapril on left ventricular mass in patients with non-insulin-dependent diabetes mellitus and hypertension. ( Bak, AA; Gerritsen, TA; Grobbee, DE; Jonker, JJ; Stolk, RP, 1998)
"The effect of short- (98 days) and long-term (1 year) treatment with nitrendipine (10 to 40 mg/d) and enalapril (5 to 20 mg/d) on kidney function was studied prospectively in a parallel group design in 16 microalbuminuric non-insulin-dependent diabetic patients with mild hypertension and biopsy-proven diabetic glomerulopathy."9.07Long-term treatment with either enalapril or nitrendipine stabilizes albuminuria and increases glomerular filtration rate in non-insulin-dependent diabetic patients. ( Bianchi, L; Campana, M; Cortesi, L; Mecca, G; Mosconi, L; Pagani, G; Remuzzi, G; Ruggenenti, P, 1994)
"After a 4-week washout period, mildly hypertensive (systolic blood pressure [sBP] > or = 140 mmHg and/or diastolic blood pressure [dBP] > or = 90 mmHg) NIDDM patients with albuminuria (15-200 micrograms/min) were randomized into an 8-month-long therapy with either nitrendipine (n = 11) or enalapril (n = 10)."5.08Effects of enalapril and nitrendipine on the excretion of epidermal growth factor and albumin in hypertensive NIDDM patients. ( Hwang, DL; Josefsberg, Z; Lev-Ran, A; Ross, SA, 1995)
"A trial to study the efficacy, safety and tolerability of nitrendipine and enalapril in the treatment of diabetic hypertensive patients with microalbuminuria (MA) was performed to compare the effects of both drugs in the prevention of the renal impairment."5.08Nitrendipine and enalapril in the treatment of diabetic hypertensive patients with microalbuminuria. ( Cases, A; Closas, J; Cobos, A; Esmatges, E; Pascual, R; Piñol, C; Planas, J; Soler, J, 1996)
"To evaluate the efficacy and tolerability of nitrendipine in comparison with captopril in hypertensive diabetic patients with left ventricular hypertrophy (LVH)."5.08Evaluation of the efficacy and tolerability of nitrendipine in reducing both pressure and left ventricular mass in hypertensive type 2 diabetic patients. ( Carraro, A; Crepaldi, G; Fasoli, G; Frigato, F; Marin, M; Nisti, S; Nosadini, R; Palisi, M; Scognamiglio, R; Virgili, F, 1997)
"To compare the effects of a calcium antagonist (nitrendipine) and an angiotensin converting enzyme inhibitor (enalapril) with those of placebo on left ventricular mass in patients with non-insulin-dependent diabetes mellitus and hypertension."5.08Effects of nitrendipine and enalapril on left ventricular mass in patients with non-insulin-dependent diabetes mellitus and hypertension. ( Bak, AA; Gerritsen, TA; Grobbee, DE; Jonker, JJ; Stolk, RP, 1998)
"The effect of short- (98 days) and long-term (1 year) treatment with nitrendipine (10 to 40 mg/d) and enalapril (5 to 20 mg/d) on kidney function was studied prospectively in a parallel group design in 16 microalbuminuric non-insulin-dependent diabetic patients with mild hypertension and biopsy-proven diabetic glomerulopathy."5.07Long-term treatment with either enalapril or nitrendipine stabilizes albuminuria and increases glomerular filtration rate in non-insulin-dependent diabetic patients. ( Bianchi, L; Campana, M; Cortesi, L; Mecca, G; Mosconi, L; Pagani, G; Remuzzi, G; Ruggenenti, P, 1994)
" We have investigated whether long-term monotherapy with a calcium antagonist, nitrendipine, prevents the development of overt diabetic nephropathy in type I and type II diabetic patients with mild to moderate hypertension and persistent microalbuminuria (ie, incipient nephropathy)."3.68Nephroprotective effects of nitrendipine in hypertensive type I and type II diabetic patients. ( Bollen, CC; Bretzel, RG; Federlin, KF; Maeser, E, 1993)
"The antihypertensive effect of nitrendipine, 20 mg once daily was studied in 30 patients with mild or moderate hypertension and type II diabetes mellitus under metabolic control."3.68Effect of nitrendipine in mild or moderate essential hypertensive subjects with type II diabetes. ( Casale, P; Papalia, D, 1991)
"We investigated renal hemodynamics and fractional clearance of neutral dextrans of graded sizes, in nine proteinuric patients with NIDDM and renal biopsy findings of typical diabetic glomerulopathy."2.69Glomerular size-selective dysfunction in NIDDM is not ameliorated by ACE inhibition or by calcium channel blockade. ( Casiraghi, F; Gambara, V; Mosconi, L; Remuzzi, A; Remuzzi, G; Ruggenenti, P; Sangalli, F, 1999)
"We report a case of type 2 diabetes mellitus presenting hypothyroidism due to overeating of seaweed that was noticed as a result of a discrepancy between glycated albumin (GA) and glycated hemoglobin (GHb)."1.33A case of type 2 diabetes mellitus developing hypothyroidism discovered as a result of a discrepancy between glycated hemoglobin and glycated albumin values. ( Arai, H; Hataya, Y; Hosoda, K; Kanamoto, N; Moriyama, K; Nakao, K; Nanbu, T, 2006)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (90.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moriyama, K1
Kanamoto, N1
Hataya, Y1
Nanbu, T1
Hosoda, K1
Arai, H1
Nakao, K1
Czupryniak, L1
Pawłowski, M1
Saryusz-Wolska, M1
Loba, J1
Fogari, R2
Zoppi, A2
Pasotti, C1
Mugellini, A2
Lusardi, P2
Lazzari, P2
Corradi, L2
Ruggenenti, P3
Mosconi, L3
Bianchi, L1
Cortesi, L1
Campana, M1
Pagani, G1
Mecca, G2
Remuzzi, G3
Giugliano, D1
De Rosa, N1
Marfella, R1
Di Maro, G1
Cacciapuoti, F1
Quatraro, A1
Acampora, R1
D'Onofrio, F1
Bretzel, RG1
Bollen, CC1
Maeser, E1
Federlin, KF1
Chan, JC1
Cockram, CS1
Nicholls, MG1
Josefsberg, Z1
Ross, SA1
Lev-Ran, A1
Hwang, DL1
Kato, S1
Ishida, H1
Tsuura, Y1
Tsuji, K1
Nishimura, M1
Horie, M1
Taminato, T1
Ikehara, S1
Odaka, H1
Ikeda, I1
Okada, Y1
Seino, Y1
Piñol, C1
Cobos, A1
Cases, A1
Esmatges, E1
Soler, J1
Closas, J1
Pascual, R1
Planas, J1
Perna, A1
Scognamiglio, R1
Nosadini, R1
Marin, M1
Nisti, S1
Fasoli, G1
Palisi, M1
Frigato, F1
Virgili, F1
Carraro, A1
Crepaldi, G1
Gerritsen, TA1
Bak, AA1
Stolk, RP1
Jonker, JJ1
Grobbee, DE1
Preti, P1
Sangalli, F1
Casiraghi, F1
Gambara, V1
Remuzzi, A1
Giuntoli, F1
Galeone, F1
Natali, A1
Gabbani, S1
Saba, P1
Papalia, D1
Casale, P1
Dolben, J1
Vora, J1
Smith, H1
Luzio, S1
Griffiths, D1
Vølund, A1
Owens, DR1
Tschöpe, D1
Rösen, P1
Gries, FA1
Gregorio, F1
Dini, FL1
Ambrosi, F1
Cristallini, S1
Pedetti, M1
Filipponi, P1

Trials

14 trials available for nitrendipine and Diabetes Mellitus, Adult-Onset

ArticleYear
Circadian blood pressure variation and antihypertensive medication adjustment in normoalbuminuric type 2 diabetes patients.
    Kidney & blood pressure research, 2007, Volume: 30, Issue:3

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Circadian Rhythm; Diab

2007
Comparative effects of ramipril and nitrendipine on albuminuria in hypertensive patients with non-insulin-dependent diabetes mellitus and impaired renal function.
    Journal of human hypertension, 1995, Volume: 9, Issue:2

    Topics: Aged; Albuminuria; Analysis of Variance; Confidence Intervals; Creatinine; Diabetes Mellitus, Type 2

1995
Long-term treatment with either enalapril or nitrendipine stabilizes albuminuria and increases glomerular filtration rate in non-insulin-dependent diabetic patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1994, Volume: 24, Issue:5

    Topics: Adult; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enalapri

1994
Comparison of nitrendipine and cilazapril in patients with hypertension and non-insulin-dependent diabetes mellitus.
    American journal of hypertension, 1993, Volume: 6, Issue:11 Pt 1

    Topics: Blood Pressure; Cilazapril; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blin

1993
Effects of enalapril and nitrendipine on the excretion of epidermal growth factor and albumin in hypertensive NIDDM patients.
    Diabetes care, 1995, Volume: 18, Issue:5

    Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomark

1995
Nitrendipine and enalapril in the treatment of diabetic hypertensive patients with microalbuminuria.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; C

1996
Nitrendipine and enalapril improve albuminuria and glomerular filtration rate in non-insulin dependent diabetes.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Calcium Channel Blocker

1996
Evaluation of the efficacy and tolerability of nitrendipine in reducing both pressure and left ventricular mass in hypertensive type 2 diabetic patients.
    Diabetes care, 1997, Volume: 20, Issue:8

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Calcium Channe

1997
Effects of nitrendipine and enalapril on left ventricular mass in patients with non-insulin-dependent diabetes mellitus and hypertension.
    Journal of hypertension, 1998, Volume: 16, Issue:5

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Enala

1998
Long-term effects of ramipril and nitrendipine on albuminuria in hypertensive patients with type II diabetes and impaired renal function.
    Journal of human hypertension, 1999, Volume: 13, Issue:1

    Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Creatinine; D

1999
Glomerular size-selective dysfunction in NIDDM is not ameliorated by ACE inhibition or by calcium channel blockade.
    Kidney international, 1999, Volume: 55, Issue:3

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Cas

1999
Antihypertensive and metabolic effects of nitrendipine in non-insulin-dependent diabetes mellitus with hypertension.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 2

    Topics: Aged; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Female; Humans; Hyperte

1992
Nitrendipine once or twice daily in hypertensive non-insulin-dependent diabetes mellitus.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 1

    Topics: Aged; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administra

1991
[Antihypertensive efficacy of nitrendipine and its effects on carbohydrate metabolism. A controlled clinical study versus placebo].
    Minerva cardioangiologica, 1991, Volume: 39, Issue:4

    Topics: Aged; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hyper

1991

Other Studies

6 other studies available for nitrendipine and Diabetes Mellitus, Adult-Onset

ArticleYear
A case of type 2 diabetes mellitus developing hypothyroidism discovered as a result of a discrepancy between glycated hemoglobin and glycated albumin values.
    Diabetes research and clinical practice, 2006, Volume: 71, Issue:3

    Topics: Aged; Antihypertensive Agents; Aspirin; Blood Cell Count; Diabetes Mellitus, Type 2; Diet; Female; G

2006
Nephroprotective effects of nitrendipine in hypertensive type I and type II diabetic patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1993, Volume: 21, Issue:6 Suppl 3

    Topics: Albuminuria; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic N

1993
Comparison of ramipril and nitrendipine.
    Journal of human hypertension, 1995, Volume: 9, Issue:11

    Topics: Albuminuria; Antihypertensive Agents; Diabetes Mellitus, Type 2; Humans; Hypertension; Nitrendipine;

1995
Alterations in basal and glucose-stimulated voltage-dependent Ca2+ channel activities in pancreatic beta cells of non-insulin-dependent diabetes mellitus GK rats.
    The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11

    Topics: Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Diabetes Mellitus, Ty

1996
Effect of nitrendipine in mild or moderate essential hypertensive subjects with type II diabetes.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 1

    Topics: Aged; Blood Pressure; Diabetes Mellitus, Type 2; Female; Heart Rate; Humans; Hypertension; Male; Mid

1991
Increase in the cytosolic concentration of calcium in platelets of diabetics type II.
    Thrombosis research, 1991, Jun-01, Volume: 62, Issue:5

    Topics: Aged; Blood Platelets; Calcium; Collagen; Cytosol; Diabetes Mellitus, Type 2; Diabetic Angiopathies;

1991