nitrendipine has been researched along with Dementia in 4 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is a risk factor for dementia, particularly vascular dementia." | 2.69 | [Antihypertensive treatment and prevention of dementia]. ( Seux, ML, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Forette, F | 2 |
| Seux, ML | 3 |
| Staessen, JA | 2 |
| Thijs, L | 1 |
| Babarskiene, MR | 1 |
| Babeanu, S | 1 |
| Bossini, A | 1 |
| Fagard, R | 1 |
| Gil-Extremera, B | 1 |
| Laks, T | 1 |
| Kobalava, Z | 1 |
| Sarti, C | 1 |
| Tuomilehto, J | 1 |
| Vanhanen, H | 1 |
| Webster, J | 1 |
| Yodfat, Y | 1 |
| Birkenhäger, WH | 2 |
| de Leeuw, PW | 1 |
| Wang, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A European Multicentre Double-blind Placebo-controlled Phase III Trial of Nilvadipine in Mild to Moderate Alzheimer's Disease[NCT02017340] | Phase 3 | 511 participants (Actual) | Interventional | 2013-04-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nitrendipine and Dementia
| Article | Year |
|---|---|
[Cognitive impairment and dementia in hypertension; the effect of antihypertensive medication].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cognition Disorders; Dementia; Humans; Hypertensi | 2000 |
2 trials available for nitrendipine and Dementia
| Article | Year |
|---|---|
The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Dementia; Double-Blind Method; Drug Therapy | 2002 |
[Antihypertensive treatment and prevention of dementia].
Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Dementia; Diur | 1999 |
1 other study available for nitrendipine and Dementia
| Article | Year |
|---|---|
Calcium-channel blockers may prevent dementia.
Topics: Calcium Channel Blockers; Dementia; Humans; Hypertension; Nitrendipine | 2003 |