nitrendipine has been researched along with Coronary Heart Disease in 18 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects on left ventricular function of postextrasystolic potentiation and the dihydropyridinic calcium antagonist diperdipine, alone or in combination, were studied in 14 patients with coronary heart disease by means of two consecutive left ventricular angiographies." | 7.68 | Synergistic action of postextrasystolic potentiation and diperdipine on left ventricular wall motion abnormalities in coronary heart disease. ( Barletta, G; Burgisser, C; Di Donato, M; Fantini, F; Maioli, M; Marchionni, N, 1992) |
| "The acute hemodynamic effects of a new dihydropyridine calcium channel blocker, diperdipine, which is suitable for intravenous administration, were studied by right and left cardiac catheterization in 16 patients with coronary heart disease." | 7.68 | Acute hemodynamic effects of intravenous diperdipine, a new dihydropyridine derivative, in coronary heart disease. ( Biamino, G; Bürgisser, C; Di Donato, M; Fantini, F; Maioli, M; Marchionni, N; Venturi, F, 1991) |
| "To examine the antianginal and antihypertensive efficacy of nitrendipine, a new calcium channel blocking agent, 25 patients with chronic stable angina pectoris (NYHA I-III) and systemic hypertension underwent cardiac catheterization and treadmill exercise tests." | 7.67 | Acute and chronic effects of nitrendipine on hemodynamics and myocardial ischemia in patients with combined angina pectoris and hypertension. ( Arendt, RM; Hauck, R; Schmoeckel, M; Schultheiss, HP, 1988) |
| "The effects of felodipine on haemodynamics and exercise capacity have been studied in patients with angina pectoris." | 5.06 | Felodipine in ischaemic heart disease. ( Sheridan, DJ; Sheridan, JV; Thomas, P, 1987) |
| "The effects on left ventricular function of postextrasystolic potentiation and the dihydropyridinic calcium antagonist diperdipine, alone or in combination, were studied in 14 patients with coronary heart disease by means of two consecutive left ventricular angiographies." | 3.68 | Synergistic action of postextrasystolic potentiation and diperdipine on left ventricular wall motion abnormalities in coronary heart disease. ( Barletta, G; Burgisser, C; Di Donato, M; Fantini, F; Maioli, M; Marchionni, N, 1992) |
| "The effect of cicletanine, a novel furopyridine antihypertensive drug was compared with that of nitrendipine, a dihydropyridine slow calcium channel blocker, on cardiac function and reperfusion-induced ventricular arrhythmias in isolated working rat hearts subjected to 10-min ischemia induced by ligation of the left main coronary artery followed by 10-min reperfusion." | 3.68 | Cicletanine improves myocardial function deteriorated by ischemia/reperfusion in isolated working rat hearts. ( Berthet, P; Braquet, P; Esanu, A; Ferdinandy, P; Koltai, M; Tarrade, T; Tosaki, A, 1992) |
| "To assess whether therapy with hydrochlorothiazide (HCTZ) or the calcium antagonist nitrendipine influences silent ischemia or arrhythmias, we studied 10 asymptomatic hypertensive male patients with positive Tl-201 scintigraphy in a double-blind, crossover protocol." | 3.68 | Influence of therapy on silent ischemia and ventricular arrhythmias in hypertensive patients. ( Ammon, S; Massie, BM; O'Kelly, B; Szlachcic, J; Tubau, JF, 1991) |
| "The acute hemodynamic effects of a new dihydropyridine calcium channel blocker, diperdipine, which is suitable for intravenous administration, were studied by right and left cardiac catheterization in 16 patients with coronary heart disease." | 3.68 | Acute hemodynamic effects of intravenous diperdipine, a new dihydropyridine derivative, in coronary heart disease. ( Biamino, G; Bürgisser, C; Di Donato, M; Fantini, F; Maioli, M; Marchionni, N; Venturi, F, 1991) |
| "To examine the antianginal and antihypertensive efficacy of nitrendipine, a new calcium channel blocking agent, 25 patients with chronic stable angina pectoris (NYHA I-III) and systemic hypertension underwent cardiac catheterization and treadmill exercise tests." | 3.67 | Acute and chronic effects of nitrendipine on hemodynamics and myocardial ischemia in patients with combined angina pectoris and hypertension. ( Arendt, RM; Hauck, R; Schmoeckel, M; Schultheiss, HP, 1988) |
| "Nitrendipine is a newly-developed calcium channel blocker derived from the dehydropyridine series which, according to experimental studies, affects marked dilation of the peripheral and coronary vessels." | 2.66 | [Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study]. ( Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W, 1985) |
| "In conclusion, in patients with chronic cardiac failure, treatment with a calcium channel blocker produced sustained haemodynamic improvement, particularly on exercise, and combination with nitrate produced further benefit." | 2.66 | Calcium channel blocker and isosorbide 5-mononitrate in the management of chronic cardiac failure. ( Hutton, I; Martin, W; McGhie, AI; Tweddel, AC, 1987) |
| "Felodipine is a dihydropyridine calcium antagonist that has a positive inotropic effect at low concentration in the dog in vivo." | 1.27 | Problem of measuring the positive inotropic property of a vasodilating drug: an illustration using felodipine. ( Drake-Holland, AJ; Mills, C; Noble, MI; Pugh, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (72.22) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rutsch, W | 1 |
| Schmutzler, H | 1 |
| Altura, BM | 1 |
| Altura, BT | 1 |
| Marchionni, N | 2 |
| Fantini, F | 2 |
| Maioli, M | 2 |
| Burgisser, C | 2 |
| Barletta, G | 1 |
| Di Donato, M | 2 |
| Ferdinandy, P | 1 |
| Koltai, M | 1 |
| Tosaki, A | 1 |
| Berthet, P | 1 |
| Tarrade, T | 1 |
| Esanu, A | 1 |
| Braquet, P | 1 |
| Nayler, WG | 2 |
| Szlachcic, J | 1 |
| Tubau, JF | 1 |
| O'Kelly, B | 1 |
| Ammon, S | 1 |
| Massie, BM | 1 |
| Venturi, F | 1 |
| Biamino, G | 1 |
| Dillon, JS | 1 |
| Elz, JS | 1 |
| McKelvie, M | 1 |
| Warltier, DC | 1 |
| Gross, GJ | 1 |
| Brooks, HL | 1 |
| Preuss, KC | 1 |
| Schmoeckel, M | 2 |
| Arendt, RM | 2 |
| Hauck, R | 2 |
| Schultheiss, HP | 2 |
| Nechwatal, W | 1 |
| Berger, J | 1 |
| Blumrich, W | 1 |
| Bouzo, H | 1 |
| Brandl, K | 1 |
| Braun, S | 1 |
| Laukaitis, A | 1 |
| Müller, G | 1 |
| Ryba, W | 1 |
| Schreiegg, J | 1 |
| Lindner, UK | 1 |
| von Manteuffel, GE | 1 |
| Stafunsky, M | 1 |
| Brügmann, U | 1 |
| Blasini, R | 1 |
| Reiniger, G | 1 |
| Rudolph, W | 1 |
| Sheridan, JV | 1 |
| Thomas, P | 1 |
| Sheridan, DJ | 1 |
| Drake-Holland, AJ | 1 |
| Pugh, S | 1 |
| Noble, MI | 1 |
| Mills, C | 1 |
| Lossnitzer, K | 1 |
| Hutton, I | 1 |
| McGhie, AI | 1 |
| Martin, W | 1 |
| Tweddel, AC | 1 |
1 review available for nitrendipine and Coronary Heart Disease
| Article | Year |
|---|---|
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
5 trials available for nitrendipine and Coronary Heart Disease
| Article | Year |
|---|---|
Comparison of the acute hemodynamic effects of nifedipine with nitrendipine and a study of the electrophysiological effects of nitrendipine in man.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Electrocardiography; El | 1984 |
A double-blind comparative study of doxazosin and nitrendipine in patients with mild-to-moderate essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease | 1988 |
[Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study].
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind | 1985 |
Felodipine in ischaemic heart disease.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Clinical Trials as Topic; Coronary Disease; D | 1987 |
Calcium channel blocker and isosorbide 5-mononitrate in the management of chronic cardiac failure.
Topics: Chronic Disease; Coronary Disease; Drug Therapy, Combination; Exercise Test; Felodipine; Heart Failu | 1987 |
12 other studies available for nitrendipine and Coronary Heart Disease
| Article | Year |
|---|---|
Synergistic action of postextrasystolic potentiation and diperdipine on left ventricular wall motion abnormalities in coronary heart disease.
Topics: Calcium Channel Blockers; Cardiac Complexes, Premature; Coronary Disease; Drug Evaluation; Female; H | 1992 |
Cicletanine improves myocardial function deteriorated by ischemia/reperfusion in isolated working rat hearts.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Coronary Circulation | 1992 |
Calcium, calcium antagonism, atherosclerosis, and ischemia.
Topics: Animals; Arteriosclerosis; Calcium; Coronary Disease; Cytosol; Humans; Hypercholesterolemia; Hyperte | 1992 |
Influence of therapy on silent ischemia and ventricular arrhythmias in hypertensive patients.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Electrocardiography, Ambulatory | 1991 |
Acute hemodynamic effects of intravenous diperdipine, a new dihydropyridine derivative, in coronary heart disease.
Topics: Calcium Channel Blockers; Coronary Disease; Female; Hemodynamics; Humans; Infusions, Intravenous; Ma | 1991 |
An effect of ischemia on myocardial dihydropyridine binding sites.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1985 |
Improvement of postischemic, contractile function by the calcium channel blocking agent nitrendipine in conscious dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Heart Rate; Myocardial Contra | 1988 |
Acute and chronic effects of nitrendipine on hemodynamics and myocardial ischemia in patients with combined angina pectoris and hypertension.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Exercise Test; Female; Hemodynamics; Humans; Hyperte | 1988 |
The addition of doxazosin to the treatment regimen of hypertensive patients not responsive to nifedipine.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease | 1988 |
[Nitrendipine in patients with coronary disease and hypertension. Acute and long-term effects on hemodynamics and myocardial ischemia].
Topics: Administration, Oral; Adult; Aged; Coronary Circulation; Coronary Disease; Female; Follow-Up Studies | 1988 |
Problem of measuring the positive inotropic property of a vasodilating drug: an illustration using felodipine.
Topics: Adult; Aged; Cardiotonic Agents; Coronary Disease; Felodipine; Female; Heart Function Tests; Hemodyn | 1987 |
[Effect and benefit of afterload reduction in coronary heart disease].
Topics: Coronary Disease; Heart Failure; Heart Ventricles; Humans; Nitrendipine; Vasodilator Agents | 1987 |