nitrendipine has been researched along with Complications of Diabetes Mellitus in 6 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitrendipine-based antihypertensive therapy is particularly beneficial in older patients with diabetes and isolated systolic hypertension." | 5.09 | Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension. Systolic Hypertension in Europe Trial Investigators. ( Antikainen, R; Birkenhäger, WH; Bulpitt, CJ; Fagard, R; Fletcher, AE; Forette, F; Goldhaber, A; Palatini, P; Rastenyte, D; Sarti, C; Thijs, L; Tuomilehto, J, 1999) |
| "In elderly Chinese patients with isolated systolic hypertension, stepwise antihypertensive drug treatment, starting with the dihydropyridine calcium channel blocker nitrendipine, improved prognosis." | 5.09 | Chinese trial on isolated systolic hypertension in the elderly. Systolic Hypertension in China (Syst-China) Collaborative Group. ( Gong, L; Liu, L; Staessen, JA; Wang, JG, 2000) |
| "In older patients with isolated systolic hypertension, antihypertensive treatment starting with the dihydropyridine calcium-channel blocker, nitrendipine, did not decrease blood pressure at the expense of renal function and prevented the development of proteinuria, especially in diabetic patients." | 5.09 | Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. ( Birkenhäger, WH; de Leeuw, PW; Efstratopoulos, AD; Fagard, R; Leonetti, G; Nachev, C; Rodicio, JL; Staessen, JA; Thijs, L; Tuomilehto, J; Voyaki, SM; Wang, JG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tuomilehto, J | 2 |
| Rastenyte, D | 1 |
| Birkenhäger, WH | 2 |
| Thijs, L | 2 |
| Antikainen, R | 1 |
| Bulpitt, CJ | 1 |
| Fletcher, AE | 1 |
| Forette, F | 1 |
| Goldhaber, A | 1 |
| Palatini, P | 1 |
| Sarti, C | 1 |
| Fagard, R | 2 |
| Salpeter, S | 1 |
| Fink, KS | 1 |
| Ellsworth, A | 1 |
| Wang, JG | 2 |
| Staessen, JA | 2 |
| Gong, L | 1 |
| Liu, L | 1 |
| Voyaki, SM | 1 |
| Efstratopoulos, AD | 1 |
| de Leeuw, PW | 1 |
| Leonetti, G | 1 |
| Nachev, C | 1 |
| Rodicio, JL | 1 |
| Ansquer, JC | 1 |
| Boussac, I | 1 |
| Lagrue, G | 1 |
3 trials available for nitrendipine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension. Systolic Hypertension in Europe Trial Investigators.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complicat | 1999 |
Chinese trial on isolated systolic hypertension in the elderly. Systolic Hypertension in China (Syst-China) Collaborative Group.
Topics: Aged; Alcohol Drinking; Antihypertensive Agents; Asian People; Blood Pressure; Captopril; Cardiovasc | 2000 |
Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.
Topics: Aged; Antihypertensive Agents; Creatinine; Diabetes Complications; Double-Blind Method; Enalapril; E | 2001 |
3 other studies available for nitrendipine and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Calcium-channel blockade and hypertension.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complicat | 1999 |
Antihypertensive treatment and CHD in the elderly.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; | 1999 |
[Treatment of arterial hypertension. Efficacy of nitrendipine 20 mg/day].
Topics: Aged; Blood Pressure Determination; Diabetes Complications; Edema; Female; Flushing; Follow-Up Studi | 1992 |