nitrendipine has been researched along with Chronic Illness in 8 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous open studies have suggested that felodipine, a selective calcium antagonist and vasodilator, may be useful in the treatment of heart failure." | 9.06 | Felodipine in patients with chronic heart failure: discrepant haemodynamic and clinical effects. ( Littler, WA; Murray, RG; Tan, LB, 1987) |
| "The acute hemodynamic response to a single oral dose of nitrendipine (10-20 mg) was evaluated in eight subjects with severe chronic congestive heart failure during right heart catheterization." | 7.67 | Acute hemodynamic effects of nitrendipine in chronic congestive heart failure. ( Cohn, JN; Levine, TB; Olivari, MT, 1984) |
| " The half-life, AUC, and bioavailability also seem to be altered only in a more severe state of liver disease." | 5.27 | Disposition of nitrendipine in patients with chronic liver diseases. ( Gothe, M; Rämsch, KD; Zilly, W, 1988) |
| "Previous open studies have suggested that felodipine, a selective calcium antagonist and vasodilator, may be useful in the treatment of heart failure." | 5.06 | Felodipine in patients with chronic heart failure: discrepant haemodynamic and clinical effects. ( Littler, WA; Murray, RG; Tan, LB, 1987) |
| "To explore the effect of dimethyl 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DCDDP) on pulmonary hypertension (PH) induced by monocrotaline (MCT), the parameters of pulmonary hemodynamics, the contents of endothelin-like immunoreactivity, nitric oxide (NO), malondialdehyde, and superoxide dismutase in plasma and pulmonary homogenate were measured." | 3.71 | Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat. ( Li, ZC; Mei, QB; Song, JC; Zhang, FQ; Zhao, DH, 2002) |
| "The acute hemodynamic response to a single oral dose of nitrendipine (10-20 mg) was evaluated in eight subjects with severe chronic congestive heart failure during right heart catheterization." | 3.67 | Acute hemodynamic effects of nitrendipine in chronic congestive heart failure. ( Cohn, JN; Levine, TB; Olivari, MT, 1984) |
| "In conclusion, in patients with chronic cardiac failure, treatment with a calcium channel blocker produced sustained haemodynamic improvement, particularly on exercise, and combination with nitrate produced further benefit." | 2.66 | Calcium channel blocker and isosorbide 5-mononitrate in the management of chronic cardiac failure. ( Hutton, I; Martin, W; McGhie, AI; Tweddel, AC, 1987) |
| " The time to Cmax was not significantly different in the two groups." | 1.27 | Steady-state pharmacokinetics of nitrendipine in hepatic insufficiency. ( Burkholder, DE; Krol, GJ; Lasseter, KC; Murdoch, AA; Shamblen, EC; Taylor, RJ; Vanov, SK, 1984) |
| " The half-life, AUC, and bioavailability also seem to be altered only in a more severe state of liver disease." | 1.27 | Disposition of nitrendipine in patients with chronic liver diseases. ( Gothe, M; Rämsch, KD; Zilly, W, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodat, L | 1 |
| Savineau, JP | 1 |
| Marthan, R | 1 |
| Guibert, C | 1 |
| Olivari, MT | 1 |
| Levine, TB | 1 |
| Cohn, JN | 1 |
| Lasseter, KC | 1 |
| Shamblen, EC | 1 |
| Murdoch, AA | 1 |
| Burkholder, DE | 1 |
| Krol, GJ | 1 |
| Taylor, RJ | 1 |
| Vanov, SK | 1 |
| Li, ZC | 1 |
| Zhang, FQ | 1 |
| Song, JC | 1 |
| Mei, QB | 1 |
| Zhao, DH | 1 |
| Zilly, W | 1 |
| Rämsch, KD | 1 |
| Gothe, M | 1 |
| Tan, LB | 1 |
| Murray, RG | 1 |
| Littler, WA | 1 |
| Kassis, E | 1 |
| Waldorff, S | 1 |
| Amtorp, O | 1 |
| Hutton, I | 1 |
| McGhie, AI | 1 |
| Martin, W | 1 |
| Tweddel, AC | 1 |
3 trials available for nitrendipine and Chronic Illness
| Article | Year |
|---|---|
Felodipine in patients with chronic heart failure: discrepant haemodynamic and clinical effects.
Topics: Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Echocardiography; Exercise Tes | 1987 |
Haemodynamic effects of felodipine during supine resting and exercising states and orthostatic tilt in patients with chronic congestive heart failure.
Topics: Antihypertensive Agents; Chronic Disease; Felodipine; Heart Failure; Hemodynamics; Humans; Nitrendip | 1987 |
Calcium channel blocker and isosorbide 5-mononitrate in the management of chronic cardiac failure.
Topics: Chronic Disease; Coronary Disease; Drug Therapy, Combination; Exercise Test; Felodipine; Heart Failu | 1987 |
5 other studies available for nitrendipine and Chronic Illness
| Article | Year |
|---|---|
Effect of chronic hypoxia on voltage-independent calcium influx activated by 5-HT in rat intrapulmonary arteries.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Chronic Disease; Cyc | 2007 |
Acute hemodynamic effects of nitrendipine in chronic congestive heart failure.
Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Output; Chronic Disease; Female; Forearm; Heart Failu | 1984 |
Steady-state pharmacokinetics of nitrendipine in hepatic insufficiency.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chronic Disea | 1984 |
Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Chronic Disease; Dicarbo | 2002 |
Disposition of nitrendipine in patients with chronic liver diseases.
Topics: Adult; Biological Availability; Chromatography, Gas; Chronic Disease; Female; Half-Life; Humans; Liv | 1988 |