nitrendipine has been researched along with Cerebrovascular Disorders in 11 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among elderly patients with isolated systolic hypertension, antihypertensive drug treatment starting with nitrendipine reduces the rate of cardiovascular complications." | 5.08 | Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. ( Arabidze, GG; Birkenhäger, WH; Bulpitt, CJ; Celis, H; de Leeuw, PW; Dollery, CT; Fagard, R; Fletcher, AE; Forette, F; Leonetti, G; Nachev, C; O'Brien, ET; Rodicio, JL; Rosenfeld, J; Staessen, JA; Thijs, L; Tuomilehto, J; Zanchetti, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Owen, A | 1 |
| Altura, BM | 1 |
| Altura, BT | 1 |
| Huang, C | 1 |
| Johns, EJ | 1 |
| Hermsmeyer, K | 1 |
| White, AC | 1 |
| Triggle, DJ | 1 |
| Staessen, JA | 2 |
| Fagard, R | 2 |
| Thijs, L | 1 |
| Celis, H | 1 |
| Arabidze, GG | 1 |
| Birkenhäger, WH | 1 |
| Bulpitt, CJ | 2 |
| de Leeuw, PW | 1 |
| Dollery, CT | 1 |
| Fletcher, AE | 1 |
| Forette, F | 2 |
| Leonetti, G | 1 |
| Nachev, C | 1 |
| O'Brien, ET | 1 |
| Rosenfeld, J | 1 |
| Rodicio, JL | 1 |
| Tuomilehto, J | 1 |
| Zanchetti, A | 1 |
| Potter, JF | 1 |
| Liu, L | 1 |
| Wang, JG | 1 |
| Gong, L | 1 |
| Liu, G | 1 |
| Sun, M | 1 |
| Zhou, H | 1 |
| Jia, Z | 1 |
| Staessen, J | 1 |
| Amery, A | 1 |
| Birkenhäger, W | 1 |
| Cox, J | 1 |
| de Leeuw, P | 1 |
| De Cort, P | 1 |
| Fletcher, A | 1 |
| Lu, JQ | 1 |
| Zhu, YH | 1 |
| Kazda, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Estudio RioplateNsE Sobre Telemonitoreo en hIpertensos No-controlAdos[NCT02730052] | 0 participants (Actual) | Interventional | 2016-12-31 | Withdrawn (stopped due to Centers recruited poorly) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitrendipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
The SYST-EUR Study--calcium channel blockers coming of age? European Trial on Isolated Systolic Hypertension in the Elderly.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Topic; | 1997 |
5 trials available for nitrendipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
MOSES: superiority or noninferiority?
Topics: Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Cerebrovascular Disorders; Clinica | 2006 |
Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; | 1997 |
Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension. Systolic Hypertension in China (Syst-China) Collaborative Group.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; | 1998 |
[Prevention and treatment of stroke after hypertension for ten years in Hunan Province].
Topics: Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Female; Humans; Hypertension; Ma | 1997 |
Syst-Eur--a multicenter trial on the treatment of isolated systolic hypertension in the elderly: first interim report.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Double- | 1992 |
4 other studies available for nitrendipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Effect of nitrendipine on renal cortical and papillary autoregulation in hypertensive rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Di | 1995 |
Decreased dihydropyridine receptor number in hypertensive rat vascular muscle cells.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; | 1995 |
Nitrendipine may protect hypertensive patients from ischemic stroke onset.
Topics: Aged; Brain Ischemia; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Middle Aged; Ni | 1992 |
Effects of nitrendipine on vascular integrity.
Topics: Animals; Blood Pressure; Cardiomegaly; Cerebrovascular Disorders; Female; Hypertension; Nitrendipine | 1986 |