nitrendipine has been researched along with Brain Ischemia in 7 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the relationships among N-methyl-D-aspartate, glycine, L-type voltage-dependent calcium channels, and [3H]dopamine release in a canine model of global cerebral ischemia/reperfusion." | 7.69 | Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia/reperfusion. ( Blanck, TJ; Fiskum, G; Fox, LG; Hoehner, PJ; Hurt, KJ; Rosenthal, RE; Werling, LL, 1994) |
| "The effect of nitrendipine, an antihypertensive calcium antagonist, on the impairment of cerebral blood flow and EEG observed after 10-min complete cerebral ischemia in anesthetized rabbits was compared with those of nicardipine." | 7.68 | Nitrendipine facilitates recovery of cerebral blood flow, EEG and metabolites following cerebral ischemia in anesthetized rabbits. ( Aihara, K; Inui, J, 1991) |
| "We investigated the relationships among N-methyl-D-aspartate, glycine, L-type voltage-dependent calcium channels, and [3H]dopamine release in a canine model of global cerebral ischemia/reperfusion." | 3.69 | Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia/reperfusion. ( Blanck, TJ; Fiskum, G; Fox, LG; Hoehner, PJ; Hurt, KJ; Rosenthal, RE; Werling, LL, 1994) |
| "The effect of nitrendipine, an antihypertensive calcium antagonist, on the impairment of cerebral blood flow and EEG observed after 10-min complete cerebral ischemia in anesthetized rabbits was compared with those of nicardipine." | 3.68 | Nitrendipine facilitates recovery of cerebral blood flow, EEG and metabolites following cerebral ischemia in anesthetized rabbits. ( Aihara, K; Inui, J, 1991) |
| "Hippocampal damage due to transient cerebral ischemia is mainly of the delayed, non-necrotic type which may arise after disruption or activation of specific cellular systems, including transmitter release through excitatory amino acid receptors." | 1.29 | The role of L-type voltage dependent calcium channels in stimulated [3H]norepinephrine release from canine hippocampal slices following global cerebral ischemia and reperfusion. ( Fiskum, G; Hurt, KJ; Rosenthal, RE; Werling, LL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hurt, KJ | 2 |
| Fiskum, G | 3 |
| Rosenthal, RE | 3 |
| Werling, LL | 2 |
| Hoehner, PJ | 3 |
| Kirsch, JR | 1 |
| Helfaer, MA | 1 |
| Ganunis, TF | 1 |
| Murphy, MT | 1 |
| Traystman, RJ | 1 |
| Fox, LG | 1 |
| Blanck, TJ | 2 |
| Bastianetto, S | 1 |
| Zheng, WH | 1 |
| Quirion, R | 1 |
| Roy, R | 1 |
| Lu, JQ | 1 |
| Zhu, YH | 1 |
| Aihara, K | 1 |
| Inui, J | 1 |
7 other studies available for nitrendipine and Brain Ischemia
| Article | Year |
|---|---|
The role of L-type voltage dependent calcium channels in stimulated [3H]norepinephrine release from canine hippocampal slices following global cerebral ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Calcium Channels; Dogs; Female; Hippocampus; N-Methylaspartate; Nitrendipin | 1995 |
Dihydropyridine ligand binding decreases earlier in adolescent than in infant swine after global cerebral ischemia.
Topics: Aging; Animals; Blood Pressure; Brain Ischemia; Calcium Channels; Caudate Nucleus; Cerebral Cortex; | 1994 |
Increased activation of L-type voltage-dependent calcium channels is associated with glycine enhancement of N-methyl-D-aspartate-stimulated dopamine release in global cerebral ischemia/reperfusion.
Topics: Animals; Brain Ischemia; Calcium Channels; Dogs; Dopamine; Female; Glycine; Isradipine; N-Methylaspa | 1994 |
The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C.
Topics: Alkaloids; Alzheimer Disease; Animals; Antioxidants; Azoles; Benzophenanthridines; Brain Ischemia; C | 2000 |
Alteration of voltage-dependent calcium channels in canine brain during global ischemia and reperfusion.
Topics: Animals; Binding Sites; Brain Ischemia; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; | 1992 |
Nitrendipine may protect hypertensive patients from ischemic stroke onset.
Topics: Aged; Brain Ischemia; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Middle Aged; Ni | 1992 |
Nitrendipine facilitates recovery of cerebral blood flow, EEG and metabolites following cerebral ischemia in anesthetized rabbits.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Electroencephalography; Energy Metaboli | 1991 |