nitrendipine has been researched along with Body Weight in 35 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and tolerability of felodipine and prazosin were compared in a double-blind randomised parallel group study of 100 patients with moderately severe essential hypertension, treated concomitantly with a beta-blocking drug." | 9.06 | Felodipine versus prazosin as an addition to a beta-blocker in the treatment of essential hypertension. The Australian Multicentre Study. ( Anderson, A; Gibson, J; Jackson, B; Morgan, TO, 1987) |
| "Fifty-one patients with essential hypertension, 22 males and 29 females with a mean age of 51 (range, 28 to 65 years), were studied for more than 12 months in a controlled clinical trial with nitrendipine, a new calcium antagonist agent." | 9.05 | Clinical experience with long-term nitrendipine treatment in essential hypertension. ( Lasaridis, A; Settas, L; Tourkantonis, A, 1984) |
| "The effectiveness and tolerability of nitrendipine (Bay e 5009) and atenolol in the treatment of mild or moderate arterial hypertension in monotherapy and in association were evaluated in a randomized double-blind study." | 9.05 | Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Petitto, M; Santomauro, M; Villari, B, 1985) |
| "The antihypertensive efficacy of once-daily nitrendipine was studied in 18 patients with severe, resistant, refractory, and complicated hypertension." | 7.68 | Long-term (3 years) sustained antihypertensive and metabolic actions of nitrendipine in severe, complicated, and resistant hypertension. ( Arocha, I; Colina-Chourio, JA; Godoy, N; Oliveros-Palacios, M, 1991) |
| "The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension." | 7.68 | Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991) |
| "Weekly subcutaneous implantation of 25-mg nitrendipine pellets prevented onset of both spontaneous and deoxycorticosterone-salt hypertension in rats." | 7.67 | Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets. ( Hall, CE; Hungerford, S, 1984) |
| "Desoxycorticosterone-salt (DOC-salt) hypertension in the rat can be prevented by administration of nitrendipine." | 7.67 | Effect of nitrendipine on blood pressure, plasma renin, and exchangeable sodium in DOC-salt hypertension in the rat. ( Brown, WB; Otipka, NA; Robertson, JI; Tonolo, G, 1987) |
| "Cyclosporine-associated hypertension (CAH) may be mediated in part by sodium and volume retention." | 5.08 | Chronic angiotensin-converting enzyme inhibition may improve sodium excretion in cardiac transplant hypertension. ( Hartmann, A; Jungmann, E; Kaltenbach, M; Kober, G; Schoeppe, W; Schwietzer, GK; Stratmann, D, 1995) |
| "The efficacy and tolerability of felodipine and prazosin were compared in a double-blind randomised parallel group study of 100 patients with moderately severe essential hypertension, treated concomitantly with a beta-blocking drug." | 5.06 | Felodipine versus prazosin as an addition to a beta-blocker in the treatment of essential hypertension. The Australian Multicentre Study. ( Anderson, A; Gibson, J; Jackson, B; Morgan, TO, 1987) |
| "Fifty-one patients with essential hypertension, 22 males and 29 females with a mean age of 51 (range, 28 to 65 years), were studied for more than 12 months in a controlled clinical trial with nitrendipine, a new calcium antagonist agent." | 5.05 | Clinical experience with long-term nitrendipine treatment in essential hypertension. ( Lasaridis, A; Settas, L; Tourkantonis, A, 1984) |
| "The effectiveness and tolerability of nitrendipine (Bay e 5009) and atenolol in the treatment of mild or moderate arterial hypertension in monotherapy and in association were evaluated in a randomized double-blind study." | 5.05 | Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Petitto, M; Santomauro, M; Villari, B, 1985) |
| "To evaluate the effect of nitrendipine on cardiac hypertrophy and inotropic response to isoproterenol in two-kidney, one-clip (2K,1C) renovascular hypertension, male Wistar rats (n = 56) were divided into a clipped group (K) (n = 28) and a sham group (S) (n = 28)." | 3.68 | Improvement of cardiac contractile response to beta-adrenergic stimulation in normal and two-kidney, one-clip hypertensive rats treated with nitrendipine. ( Fontan, M; Gallo, A; Gómez Llambi, H; Mazzadi, A; Taquini, CM, 1991) |
| "The antihypertensive efficacy of once-daily nitrendipine was studied in 18 patients with severe, resistant, refractory, and complicated hypertension." | 3.68 | Long-term (3 years) sustained antihypertensive and metabolic actions of nitrendipine in severe, complicated, and resistant hypertension. ( Arocha, I; Colina-Chourio, JA; Godoy, N; Oliveros-Palacios, M, 1991) |
| "The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension." | 3.68 | Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991) |
| "The antihypertensive efficacy of the calcium entry blocker nitrendipine administered as monotherapy (20-80 mg; mean, 36/day) on the average for 144 days to 46 patients with essential hypertension (WHO I and II) was investigated in relation to age, pretreatment blood pressure, and plasma renin activity." | 3.67 | Antihypertensive therapy with the long-acting calcium antagonist nitrendipine. ( Block, LH; Bolli, P; Bühler, FR; Erne, P; Kiowski, W; Müller, FB, 1984) |
| "Weekly subcutaneous implantation of 25-mg nitrendipine pellets prevented onset of both spontaneous and deoxycorticosterone-salt hypertension in rats." | 3.67 | Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets. ( Hall, CE; Hungerford, S, 1984) |
| "Desoxycorticosterone-salt (DOC-salt) hypertension in the rat can be prevented by administration of nitrendipine." | 3.67 | Effect of nitrendipine on blood pressure, plasma renin, and exchangeable sodium in DOC-salt hypertension in the rat. ( Brown, WB; Otipka, NA; Robertson, JI; Tonolo, G, 1987) |
| "Nitrendipine treatment did not influence left ventricular mass (which was positively correlated with delta BW; p less than 0." | 2.67 | Salt and water retention and calcium blockade in uremia. ( Fabiani, F; Froment, L; Guerin, AP; London, GM; Marchais, SJ; Metivier, F; Safar, ME, 1990) |
| " Nitrendipine (mean dose 32 mg/day) and acebutolol (414 mg/day) were administered in monotherapy in increasing dosage and mefruside was added in patients not controlled by monotherapy." | 2.66 | Calcium entry blockade or beta-blockade in long-term management of hypertension in blacks. ( Amery, A; Ditu, M; Fagard, R; Lepira, B; Lijnen, P; Lissens, W; M'Buyamba-Kabangu, JR; Staessen, J; Tshiani, KA, 1987) |
| "T-type Ca(2+) channel blockade reduced arrhythmias in a mouse model of dilated cardiomyopathy by repolarizing the resting membrane potential and improving cardiac autonomic nervous system imbalance." | 1.35 | T-type Ca2+ channel blockade prevents sudden death in mice with heart failure. ( Arai, Y; Fujiwara, M; Harada, M; Kinoshita, H; Kuwabara, Y; Kuwahara, K; Murakami, M; Nakagawa, Y; Nakanishi, M; Nakao, K; Takano, M; Ueshima, K; Yasuno, S, 2009) |
| " The test substance proved to be only mildly toxic after repeated (up to 3 months) oral administration." | 1.29 | Experimental studies on the toxicity of diperdipine following oral and parenteral application. ( Herzog, R; Leuschner, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (57.14) | 18.7374 |
| 1990's | 14 (40.00) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinoshita, H | 1 |
| Kuwahara, K | 1 |
| Takano, M | 1 |
| Arai, Y | 1 |
| Kuwabara, Y | 1 |
| Yasuno, S | 1 |
| Nakagawa, Y | 1 |
| Nakanishi, M | 1 |
| Harada, M | 1 |
| Fujiwara, M | 1 |
| Murakami, M | 1 |
| Ueshima, K | 1 |
| Nakao, K | 1 |
| Müller, FB | 1 |
| Bolli, P | 1 |
| Erne, P | 1 |
| Block, LH | 1 |
| Kiowski, W | 1 |
| Bühler, FR | 1 |
| Weber, MA | 1 |
| Drayer, JI | 1 |
| Tourkantonis, A | 1 |
| Lasaridis, A | 1 |
| Settas, L | 1 |
| Fritschka, E | 1 |
| Distler, A | 1 |
| Gotzen, R | 1 |
| Thiede, HM | 1 |
| Philipp, T | 1 |
| Nickerson, PA | 2 |
| Kobrin, I | 1 |
| Sesoko, S | 1 |
| Pegram, BL | 1 |
| Frohlich, ED | 1 |
| Hall, CE | 1 |
| Hungerford, S | 1 |
| Schwietzer, GK | 1 |
| Hartmann, A | 1 |
| Kober, G | 1 |
| Jungmann, E | 1 |
| Stratmann, D | 1 |
| Kaltenbach, M | 1 |
| Schoeppe, W | 1 |
| Herzog, R | 1 |
| Leuschner, J | 1 |
| Awumey, EM | 1 |
| Pehowich, DJ | 1 |
| Hochhauser, E | 1 |
| Kushnir, T | 1 |
| Navon, G | 1 |
| Rehavi, M | 1 |
| Barak, J | 1 |
| Edelstein, S | 1 |
| Vidne, B | 1 |
| Yoshida, M | 1 |
| Latifpour, J | 1 |
| Weiss, RM | 1 |
| Harvey, PJ | 1 |
| Wing, LM | 1 |
| Beilby, J | 1 |
| Ramsay, A | 1 |
| Tonkin, AL | 1 |
| Goh, SH | 1 |
| Russell, AE | 1 |
| Bune, AJ | 1 |
| Chalmers, JP | 1 |
| Okopién, B | 1 |
| Trzeciak, HI | 1 |
| Scalbert, E | 1 |
| Narcisse, G | 1 |
| Abdon, D | 1 |
| Fauchère, JL | 1 |
| Santoni, JP | 1 |
| Taquini, CM | 1 |
| Gómez Llambi, H | 1 |
| Mazzadi, A | 1 |
| Fontan, M | 1 |
| Gallo, A | 1 |
| Colina-Chourio, JA | 1 |
| Godoy, N | 1 |
| Oliveros-Palacios, M | 1 |
| Arocha, I | 1 |
| Knorr, A | 1 |
| Kazda, S | 1 |
| Neuser, D | 1 |
| Stasch, JP | 1 |
| Seuter, F | 1 |
| Schmieder, RE | 1 |
| Rockstroh, JK | 1 |
| Münch, HG | 1 |
| Rüddel, H | 1 |
| Schlebusch, H | 1 |
| Yang, F | 1 |
| London, GM | 1 |
| Marchais, SJ | 1 |
| Guerin, AP | 1 |
| Metivier, F | 1 |
| Safar, ME | 1 |
| Fabiani, F | 1 |
| Froment, L | 1 |
| Finkel, MS | 1 |
| Marks, ES | 1 |
| Patterson, RE | 1 |
| Speir, EH | 1 |
| Steadman, KA | 1 |
| Keiser, HR | 1 |
| Häberle, DA | 1 |
| Kawata, T | 1 |
| Davis, JM | 1 |
| Otipka, NA | 1 |
| Tonolo, G | 2 |
| Brown, WB | 1 |
| Robertson, JI | 1 |
| Glorioso, N | 1 |
| Manunta, P | 1 |
| Troffa, C | 1 |
| Pazzola, A | 1 |
| Soro, A | 1 |
| Pala, F | 1 |
| Melis, MG | 1 |
| Madeddu, P | 1 |
| Liedholm, H | 1 |
| Melander, A | 1 |
| Galletti, F | 1 |
| Strazzullo, P | 1 |
| Cappuccio, FP | 1 |
| Barba, G | 1 |
| Giorgione, N | 1 |
| Gagliardi, R | 1 |
| Mancini, M | 1 |
| Kloke, HJ | 1 |
| Huysmans, FT | 1 |
| Wetzels, JF | 1 |
| Sluiter, HE | 1 |
| Kleinbloesem, CH | 1 |
| Koene, RA | 1 |
| Abelardo, NS | 1 |
| Ramos, EF | 1 |
| Mendoza, VL | 1 |
| Sulit, YQ | 1 |
| Mitchell, MJ | 1 |
| M'Buyamba-Kabangu, JR | 2 |
| Lepira, B | 2 |
| Fagard, R | 2 |
| Lijnen, P | 2 |
| Ditu, M | 2 |
| Tshiani, KA | 2 |
| Amery, A | 2 |
| Jackson, B | 1 |
| Morgan, TO | 1 |
| Gibson, J | 1 |
| Anderson, A | 1 |
| Jansen, RW | 1 |
| Van Lier, HJ | 1 |
| Hoefnagels, WH | 1 |
| de Divitiis, O | 1 |
| Petitto, M | 1 |
| Di Somma, S | 1 |
| Galderisi, M | 1 |
| Villari, B | 1 |
| Santomauro, M | 1 |
| Fazio, S | 1 |
| Staessen, J | 1 |
| Lissens, W | 1 |
14 trials available for nitrendipine and Body Weight
| Article | Year |
|---|---|
Clinical experience with long-term nitrendipine treatment in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Blood Proteins; Body Weight; Calcium; Calcium Channel Blockers; Clinica | 1984 |
Crossover comparison of nitrendipine with propranolol in patients with essential hypertension.
Topics: Adult; Blood Pressure; Body Weight; Calcium Channel Blockers; Catecholamines; Humans; Hypertension; | 1984 |
Chronic angiotensin-converting enzyme inhibition may improve sodium excretion in cardiac transplant hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Body Weight; Creatinine; Cross-Over Studie | 1995 |
Effect of indomethacin on blood pressure control during treatment with nitrendipine.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Blood Pressure; Body Weight; Double-Blind Method; Fem | 1995 |
Salt and water retention and calcium blockade in uremia.
Topics: Aorta; Blood Chemical Analysis; Blood Pressure; Body Weight; Echocardiography; Heart Rate; Humans; H | 1990 |
Effects of nitrendipine on blood pressure, renin-angiotensin system, and kidney function in essential hypertension.
Topics: Adult; Blood Pressure; Body Weight; Captopril; Heart Rate; Humans; Hypertension; Kidney; Kidney Func | 1988 |
A placebo-controlled dose-response study of felodipine extended release in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Clinical Trials as Topic; Dose-R | 1989 |
Antihypertensive effects of nitrendipine and cilazapril alone, and in combination in hypertensive patients with chronic renal failure.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Body Weight; Calcium Channel Blockers; Cilazapril; | 1989 |
A comparison of felodipine and nifedipine as monotherapies for the treatment of mild to moderate hypertension.
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Felodipine; Femal | 1989 |
Relative potency of a beta-blocking and a calcium entry blocking agent as antihypertensive drugs in black patients.
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Black or | 1986 |
Felodipine versus prazosin as an addition to a beta-blocker in the treatment of essential hypertension. The Australian Multicentre Study.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials a | 1987 |
Nitrendipine versus hydrochlorothiazide in hypertensive patients over 70 years of age.
Topics: Aged; Body Weight; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazid | 1989 |
Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension.
Topics: Adult; Atenolol; Blood Pressure; Body Weight; Calcium Channel Blockers; Clinical Trials as Topic; Do | 1985 |
Calcium entry blockade or beta-blockade in long-term management of hypertension in blacks.
Topics: Acebutolol; Adolescent; Adult; Aged; Black or African American; Body Weight; Double-Blind Method; Dr | 1987 |
21 other studies available for nitrendipine and Body Weight
| Article | Year |
|---|---|
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Body Weight; Calcium Channe | 2009 |
Antihypertensive therapy with the long-acting calcium antagonist nitrendipine.
Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Female; Heart Rate; Humans; Hype | 1984 |
The calcium channel blocker nitrendipine in single- and multiple-agent antihypertensive regimens: preliminary report of a multicenter study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcium Channel Blockers; Drug Therapy, Combi | 1984 |
A low dose of a calcium antagonist (nitrendipine) ameliorates cardiac and renal lesions induced by DOC in the rat.
Topics: Animals; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Drug Interactions; Female; Hear | 1984 |
Reduced cardiac mass by nitrendipine is dissociated from systemic or regional haemodynamic changes in rats.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Body Weight; Calcium Channel Blockers; Heart; Hemodyna | 1984 |
Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets.
Topics: Animals; Antihypertensive Agents; Body Weight; Desoxycorticosterone; Female; Hypertension; Nifedipin | 1984 |
Experimental studies on the toxicity of diperdipine following oral and parenteral application.
Topics: Administration, Oral; Animals; Blood Cell Count; Body Weight; Calcium Channel Blockers; Eye Diseases | 1995 |
N-3 and N-6 fatty acids modulate the inotropic response to calcium in hypothyroid rat papillary muscle.
Topics: Animals; Body Weight; Calcium; Diet; Dietary Fats, Unsaturated; Fatty Acids, Omega-3; Fatty Acids, O | 1995 |
The effect of vitamin D3 deficiency on the isolated chick heart: hemodynamic, P-31 NMR and membrane studies.
Topics: Animals; Body Weight; Calcium; Chickens; Cholecalciferol; Heart; Magnetic Resonance Spectroscopy; My | 1993 |
Age-related changes in Ca2+ channel antagonist receptors in rabbit lower urinary tract.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Calcium Channel Agonists; Calcium Channels; Female; I | 1993 |
Modification of adrenergic reactivity in rat tail artery by dietary lipids and calcium channel antagonists.
Topics: Animals; Arteries; Body Weight; Calcium Channel Blockers; Diet, Atherogenic; Dietary Fats; In Vitro | 1996 |
Systemic and regional hemodynamic interactions of perindopril and nitrendipine in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diuresis; Drug Synergism; Heart Rate; | 1990 |
Improvement of cardiac contractile response to beta-adrenergic stimulation in normal and two-kidney, one-clip hypertensive rats treated with nitrendipine.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Heart; Hypertension, Renal; Isoproterenol; Male; | 1991 |
Long-term (3 years) sustained antihypertensive and metabolic actions of nitrendipine in severe, complicated, and resistant hypertension.
Topics: Adult; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hypertension; Kidney; Male; Middle A | 1991 |
Long-term protective effects of nitrendipine in experimental hypertension.
Topics: Animals; Arteriosclerosis; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Endothelins; Hydr | 1991 |
Elevated serum activity of N-acetyl-beta-glucosaminidase in essential hypertension: diagnostic value and reversal to normal values after antihypertensive therapy.
Topics: Acetylglucosaminidase; Adult; Age Factors; Blood Pressure; Body Weight; Clinical Enzyme Tests; Femal | 1991 |
Effect of nitrendipine on cardiac and renal lesions and arterial hypertrophy. Protective effect of a low dose of calcium antagonist in deoxycorticosterone-induced hypertensive rats.
Topics: Animals; Aorta; Arteries; Arterioles; Blood Pressure; Body Weight; Coronary Vessels; Desoxycorticost | 1990 |
Correlation of changes in cardiac calcium channels with hemodynamics in Syrian hamster cardiomyopathy and heart failure.
Topics: Animals; Body Weight; Calcium; Cardiomyopathies; Cricetinae; Heart Failure; Hemodynamics; Humans; In | 1987 |
The site of action of nitrendipine in the rat kidney.
Topics: Animals; Blood Pressure; Body Weight; Glomerular Filtration Rate; Kidney; Kidney Tubules, Proximal; | 1987 |
Effect of nitrendipine on blood pressure, plasma renin, and exchangeable sodium in DOC-salt hypertension in the rat.
Topics: Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Hypertension; Male; Nephrectomy; Nitrend | 1987 |
Calcium-channel blockers and sodium intake: a controlled study in patients with essential hypertension.
Topics: Adult; Blood Pressure; Body Weight; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Mi | 1989 |