Page last updated: 2024-11-01

nitrendipine and Ataxia

nitrendipine has been researched along with Ataxia in 3 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
" Acute nitrendipine significantly increased the latency of seizures in response to the partial benzodiazepine inverse agonist FG7142 during barbiturate withdrawal, but there was no effect on the seizure incidence in response to bicuculline."3.69Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal. ( Brown, J; Butterworth, AR; Little, HJ; Rabbani, M, 1994)
" Chronic administration of felodipine for 2 weeks did not produce tolerance to the sedative effect of felodipine or cross-tolerance to nitrendipine."1.30Differing acute interactions of ethanol with two structurally related dihydropyridines, nitrendipine and felodipine. ( Homewood, N; Little, HJ; Watson, WP, 1998)
"Clonazepam did not produce anaesthesia, at doses up to 1 g kg-1 or when given with nitrendipine."1.28Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644. ( Dolin, SJ; Little, HJ; Patch, TL; Rabbani, M; Taberner, PV, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rabbani, M2
Brown, J1
Butterworth, AR1
Little, HJ3
Watson, WP1
Homewood, N1
Dolin, SJ1
Patch, TL1
Taberner, PV1

Other Studies

3 other studies available for nitrendipine and Ataxia

ArticleYear
Dihydropyridine-sensitive calcium channels and barbiturate tolerance and withdrawal.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Anesthesia, General; Animals; Ataxia; Barbiturates; Bicuculline; Calcium Channels; Carbolines; Dihyd

1994
Differing acute interactions of ethanol with two structurally related dihydropyridines, nitrendipine and felodipine.
    Brain research bulletin, 1998, Nov-01, Volume: 47, Issue:4

    Topics: Anesthesia, General; Animals; Ataxia; Calcium Channel Blockers; Drug Interactions; Ethanol; Felodipi

1998
Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644.
    Neuropharmacology, 1991, Volume: 30, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991