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nitrendipine and Asthma

nitrendipine has been researched along with Asthma in 4 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Nitrendipine was given to eight patients with chronic stable asthma prior to a histamine challenge study and compared in a double-blind cross-over fashion with placebo."9.06Nitrendipine therapy in asthmatic subjects. ( Cormie, P; Harvey, J; Marley, JE; Mulloy, EM, 1990)
"Felodipine is a new calcium antagonist of the dihydropyridine group with a high selectivity for arteriolar smooth muscle; it is under clinical investigation for the treatment of hypertension."6.66Felodipine, a new calcium antagonist, modifies exercise-induced asthma. ( Patel, KR; Peers, E, 1988)
"Nitrendipine was given to eight patients with chronic stable asthma prior to a histamine challenge study and compared in a double-blind cross-over fashion with placebo."5.06Nitrendipine therapy in asthmatic subjects. ( Cormie, P; Harvey, J; Marley, JE; Mulloy, EM, 1990)
"Felodipine is a new calcium antagonist of the dihydropyridine group with a high selectivity for arteriolar smooth muscle; it is under clinical investigation for the treatment of hypertension."2.66Felodipine, a new calcium antagonist, modifies exercise-induced asthma. ( Patel, KR; Peers, E, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baraldi, PG1
Preti, D1
Materazzi, S1
Geppetti, P1
Sweeney, D1
Hollins, F1
Gomez, E1
Saunders, R1
Challiss, RA1
Brightling, CE1
Mulloy, EM1
Cormie, P1
Harvey, J1
Marley, JE1
Patel, KR1
Peers, E1

Reviews

1 review available for nitrendipine and Asthma

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe

2010

Trials

2 trials available for nitrendipine and Asthma

ArticleYear
Nitrendipine therapy in asthmatic subjects.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:3

    Topics: Adult; Asthma; Double-Blind Method; Female; Histamine; Humans; Hypertension; Male; Maximal Expirator

1990
Felodipine, a new calcium antagonist, modifies exercise-induced asthma.
    The American review of respiratory disease, 1988, Volume: 138, Issue:1

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Blood Pressure; Calcium Channel Blockers; Felodipine; Femal

1988

Other Studies

1 other study available for nitrendipine and Asthma

ArticleYear
[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma.
    Respirology (Carlton, Vic.), 2014, Volume: 19, Issue:5

    Topics: Adult; Aged; Asthma; Biopsy; Caffeine; Calcium Signaling; Case-Control Studies; Female; Forced Expir

2014