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nitrendipine and Arteriosclerosis

nitrendipine has been researched along with Arteriosclerosis in 11 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
"The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension."7.68Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991)
"The relationship between the presence of arterial calcinosis and the antihypertensive response to calcium blockers was studied in 40 hypertensive patients with end-stage renal failure (ESRF) on chronic hemodialysis, before and during 16 weeks after administration of nitrendipine in monotherapy."5.07Arteriosclerosis and antihypertensive response to calcium antagonists in end-stage renal failure. ( Boussac, I; Delavaux, G; Guerin, AP; London, GM; Marchais, SJ; Metivier, F, 1991)
"The relationship between the presence of arterial calcinosis and the antihypertensive response to calcium blockers was studied in 40 hypertensive patients with end-stage renal failure (ESRF) on chronic hemodialysis, before and during 16 weeks after administration of nitrendipine in monotherapy."5.07Arteriosclerosis and antihypertensive response to calcium antagonists in end-stage renal failure. ( Boussac, I; Delavaux, G; Guerin, AP; London, GM; Marchais, SJ; Metivier, F, 1991)
" The atherogenic significance of Ca ions and arterial Ca overload was examined under the influence of nicotine, oxidatively modified low-density lipoproteins, spontaneous hypertension, and an elevated extracellular Ca concentration or vitamin D3."3.69Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations. ( Czirfuzs, A; Fleckenstein-Grün, G; Frey, M; Matyas, S; Thimm, F, 1994)
"The antihypertensive and tissue-protective effects of nitrendipine were studied after long-term treatment of rats with experimental hypertension."3.68Long-term protective effects of nitrendipine in experimental hypertension. ( Kazda, S; Knorr, A; Neuser, D; Seuter, F; Stasch, JP, 1991)
"Aortic stiffness and left ventricular hypertrophy (LVH) are predictors of mortality in hemodialysis (HD) patients."2.71Inflammation, arteriosclerosis, and cardiovascular therapy in hemodialysis patients. ( Adda, H; Guerin, AP; London, GM; Marchais, SJ; Metivier, F; Pannier, B, 2003)
"Nitrendipine (Bayotensin) is a dihydropyridine derivative that appears to preferentially dilate peripheral vessels by a cellular mechanism similar to those found with other calcium blocking agents."1.27Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals. ( Basista, E; Basista, M; Grodzińska, L; Ohlrogge, R; Stachura, J; Swies, J; Sławiński, M, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's7 (63.64)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
London, GM3
Marchais, SJ3
Guerin, AP3
Metivier, F3
Adda, H1
Pannier, B1
Fleckenstein-Grün, G1
Thimm, F1
Czirfuzs, A1
Matyas, S1
Frey, M1
Madsen, JK1
Jensen, JW1
Sandermann, J1
Johannesen, N1
Paaske, WP1
Egeblad, M1
Pedersen, EB1
Corsini, A1
Accomazzo, MR1
Canavesi, M1
Sartani, A1
Testa, R1
Catapano, AL1
Fumagalli, R1
Paoletti, R1
Bernini, F1
Matsumura, Y1
Hayashi, K1
Nayler, WG1
Boussac, I2
Delavaux, G2
Knorr, A1
Kazda, S1
Neuser, D1
Stasch, JP1
Seuter, F2
Grodzińska, L1
Basista, M1
Basista, E1
Sławiński, M1
Swies, J1
Stachura, J1
Ohlrogge, R1

Reviews

1 review available for nitrendipine and Arteriosclerosis

ArticleYear
Vatanidipine hydrochloride: a new long-lasting antihypertensive agent.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:1

    Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Clinical Trials as Top

2001

Trials

4 trials available for nitrendipine and Arteriosclerosis

ArticleYear
Inflammation, arteriosclerosis, and cardiovascular therapy in hemodialysis patients.
    Kidney international. Supplement, 2003, Issue:84

    Topics: Adult; Antihypertensive Agents; Aortic Diseases; Arteriosclerosis; Atenolol; Blood Pressure; C-React

2003
Effect of nitrendipine on renal function and on hormonal parameters after intravascular iopromide.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: Adult; Aged; Aortography; Arteriosclerosis; Calcium Channel Blockers; Contrast Media; Double-Blind M

1998
Arteriosclerosis and antihypertensive response to calcium antagonists in end-stage renal failure.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 1

    Topics: Adult; Aged; Aging; Aortic Diseases; Arteriosclerosis; Blood Pressure; Calcinosis; Double-Blind Meth

1991
Arteriosclerosis and antihypertensive response to calcium antagonists in end-stage renal failure.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 5

    Topics: Administration, Oral; Aged; Analysis of Variance; Arteriosclerosis; Blood Pressure; Calcinosis; Doub

1991

Other Studies

6 other studies available for nitrendipine and Arteriosclerosis

ArticleYear
Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations.
    Journal of cardiovascular pharmacology, 1994, Volume: 24 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cells,

1994
The new calcium antagonist lercanidipine and its enantiomers affect major processes of atherogenesis in vitro: is calcium entry involved?
    Blood pressure. Supplement, 1998, Volume: 2

    Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Brain; Calcium Channel Blockers; Cell Division;

1998
Calcium, calcium antagonism, atherosclerosis, and ischemia.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 2

    Topics: Animals; Arteriosclerosis; Calcium; Coronary Disease; Cytosol; Humans; Hypercholesterolemia; Hyperte

1992
Long-term protective effects of nitrendipine in experimental hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 5

    Topics: Animals; Arteriosclerosis; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Endothelins; Hydr

1991
[Pharmacologic inhibition of experimental atherosclerosis].
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 6

    Topics: Animals; Arteriosclerosis; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug;

1989
Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:4

    Topics: Animals; Arteriosclerosis; Cats; Diet; Epoprostenol; Female; Male; Nitrendipine; Platelet Aggregatio

1987