Page last updated: 2024-11-01

nitrendipine and Arrhythmia

nitrendipine has been researched along with Arrhythmia in 14 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
" We therefore decided to compare the influence of oral and intravenous administration of furnidipine, nifedipine, nitrendipine and nimodipine to examine their effects on hemodynamics and arrhythmias."3.78Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine. ( Krzemiński, TF; Mitręga, KA; Porc, M; Varghese, B, 2012)
"The effect of cicletanine, a novel furopyridine antihypertensive drug was compared with that of nitrendipine, a dihydropyridine slow calcium channel blocker, on cardiac function and reperfusion-induced ventricular arrhythmias in isolated working rat hearts subjected to 10-min ischemia induced by ligation of the left main coronary artery followed by 10-min reperfusion."3.68Cicletanine improves myocardial function deteriorated by ischemia/reperfusion in isolated working rat hearts. ( Berthet, P; Braquet, P; Esanu, A; Ferdinandy, P; Koltai, M; Tarrade, T; Tosaki, A, 1992)
"To assess whether therapy with hydrochlorothiazide (HCTZ) or the calcium antagonist nitrendipine influences silent ischemia or arrhythmias, we studied 10 asymptomatic hypertensive male patients with positive Tl-201 scintigraphy in a double-blind, crossover protocol."3.68Influence of therapy on silent ischemia and ventricular arrhythmias in hypertensive patients. ( Ammon, S; Massie, BM; O'Kelly, B; Szlachcic, J; Tubau, JF, 1991)
"In this mouse model of dilated cardiomyopathy leading to sudden arrhythmic death, cardiac structure and function did not significantly differ among the control, cilnidipine, and nitrendipine groups."1.40Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure. ( Arai, Y; Cho, K; Kamakura, S; Kangawa, K; Kimura, T; Kinoshita, H; Kiyonaka, S; Kuwabara, Y; Kuwahara, K; Minami, T; Mori, Y; Nakagawa, Y; Nakao, K; Nishida, M; Nishikimi, T; Shibata, J; Ueshima, K; Yamada, C; Yamada, Y; Yasuno, S, 2014)
"T-type Ca(2+) channel blockade reduced arrhythmias in a mouse model of dilated cardiomyopathy by repolarizing the resting membrane potential and improving cardiac autonomic nervous system imbalance."1.35T-type Ca2+ channel blockade prevents sudden death in mice with heart failure. ( Arai, Y; Fujiwara, M; Harada, M; Kinoshita, H; Kuwabara, Y; Kuwahara, K; Murakami, M; Nakagawa, Y; Nakanishi, M; Nakao, K; Takano, M; Ueshima, K; Yasuno, S, 2009)
"NT reduced the duration of continuous arrhythmias at the beginning of reperfusion (to 59."1.31Comparison of effects of nitrendipine, lacidipine and mibefradil on postischaemic myocardial damage in isolated rat hearts. ( Arh, M; Budihna, MV, 2000)
"Verapamil was more effective than diltiazem."1.27Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber. ( Endou, K; Sato, T; Yamamoto, H, 1987)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's2 (14.29)18.2507
2000's3 (21.43)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jia, L1
Sun, H1
Yamada, Y1
Kinoshita, H2
Kuwahara, K2
Nakagawa, Y2
Kuwabara, Y2
Minami, T1
Yamada, C1
Shibata, J1
Nakao, K3
Cho, K1
Arai, Y2
Yasuno, S2
Nishikimi, T1
Ueshima, K2
Kamakura, S1
Nishida, M1
Kiyonaka, S1
Mori, Y1
Kimura, T1
Kangawa, K1
Takano, M1
Nakanishi, M1
Harada, M1
Fujiwara, M1
Murakami, M1
Mitręga, KA1
Varghese, B1
Porc, M1
Krzemiński, TF1
Gould, RJ1
Murphy, KM1
Reynolds, IJ1
Snyder, SH1
Arh, M1
Budihna, MV1
Ferdinandy, P1
Koltai, M1
Tosaki, A1
Berthet, P1
Tarrade, T1
Esanu, A1
Braquet, P1
Szlachcic, J1
Tubau, JF1
O'Kelly, B1
Ammon, S1
Massie, BM1
January, CT1
Riddle, JM1
Nahas, G2
Trouvé, R2
Demus, JR1
von Sitbon, M1
Scardi, S1
Pivotti, F1
Pandullo, C1
Ceschia, G1
Salvi, A1
Endou, K1
Yamamoto, H1
Sato, T1
Bush, LR1
Evans, RM1
Gaul, SL1
D'Alonzo, AJ1

Other Studies

14 other studies available for nitrendipine and Arrhythmia

ArticleYear
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant

2008
Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure.
    Cardiovascular research, 2014, Oct-01, Volume: 104, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nervou

2014
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Body Weight; Calcium Channe

2009
Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.
    Pharmacological research, 2012, Volume: 66, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Car

2012
Calcium channel blockade: possible explanation for thioridazine's peripheral side effects.
    The American journal of psychiatry, 1984, Volume: 141, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Ejaculation; Female; Ion Channels; Male; Mu

1984
Comparison of effects of nitrendipine, lacidipine and mibefradil on postischaemic myocardial damage in isolated rat hearts.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:5 Suppl

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Fem

2000
Cicletanine improves myocardial function deteriorated by ischemia/reperfusion in isolated working rat hearts.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Coronary Circulation

1992
Influence of therapy on silent ischemia and ventricular arrhythmias in hypertensive patients.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 1

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Electrocardiography, Ambulatory

1991
Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current.
    Circulation research, 1989, Volume: 64, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
A calcium-channel blocker as antidote to the cardiac effects of cocaine intoxication.
    The New England journal of medicine, 1985, Aug-22, Volume: 313, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Cocaine; Dogs; Nifedipine; Nitrendipine; Ra

1985
Exercise-induced intermittent angina and ST-segment elevation in Prinzmetal's angina.
    European heart journal, 1988, Volume: 9, Issue:1

    Topics: Angina Pectoris, Variant; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diltiazem; Electrocardiograp

1988
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
    Japanese heart journal, 1987, Volume: 28, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiaze

1987
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
    Pharmacology, 1987, Volume: 34, Issue:2-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Fe

1987
Nitrendipine: an antidote to cardiac and lethal toxicity of cocaine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 183, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cocaine; Drug Interactions; Heart; Heart Rate; Nitren

1986