nitrendipine has been researched along with Angor Pectoris in 13 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The introduction of phosphodiesterase-5 inhibitors as sildenafil, tadalafil, or vardenafil, has tremendously improved the treatment of erectile dysfunction." | 9.13 | Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition. ( Jung, F; Leithäuser, B; Park, JW, 2008) |
| "The relative efficacies of 240 mg/day diltiazem and 20 mg/day nitrendipine were compared in a placebo-controlled, randomized, crossover study of 48 patients who had both moderate systemic hypertension and stable angina pectoris." | 9.07 | Comparison of diltiazem, nitrendipine, and their combination for systemic hypertension and stable angina pectoris. ( Andreyev, N; Andreyeva, T; Bichkov, I; Skutelis, A, 1991) |
| "We studied the effects of adding felodipine to beta-adrenoceptor blockade on haemodynamics and exercise capacity in 14 patients with stable angina pectoris using a placebo controlled double-blind crossover protocol." | 9.06 | Effects of felodipine on haemodynamics and exercise capacity in patients with angina pectoris. ( Routledge, PA; Sheridan, DJ; Sheridan, JV; Thomas, P, 1987) |
| "To investigate the antianginal efficacy, duration of action and tolerability of 2 doses of the new calcium antagonist felodipine, 15 patients (14 men and 1 woman, mean age 62 years) with stable exertional angina pectoris and angiographically demonstrated coronary artery disease were randomly given felodipine, 5 and 10 mg, and placebo on 3 different days." | 9.06 | Acute effects of felodipine in exertional angina pectoris. ( Ceschia, G; Pandullo, C; Pivotti, F; Pollavini, G; Scardi, S, 1988) |
| "To examine the antianginal and antihypertensive efficacy of nitrendipine, a new calcium channel blocking agent, 25 patients with chronic stable angina pectoris (NYHA I-III) and systemic hypertension underwent cardiac catheterization and treadmill exercise tests." | 7.67 | Acute and chronic effects of nitrendipine on hemodynamics and myocardial ischemia in patients with combined angina pectoris and hypertension. ( Arendt, RM; Hauck, R; Schmoeckel, M; Schultheiss, HP, 1988) |
| "The introduction of phosphodiesterase-5 inhibitors as sildenafil, tadalafil, or vardenafil, has tremendously improved the treatment of erectile dysfunction." | 5.13 | Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition. ( Jung, F; Leithäuser, B; Park, JW, 2008) |
| "The relative efficacies of 240 mg/day diltiazem and 20 mg/day nitrendipine were compared in a placebo-controlled, randomized, crossover study of 48 patients who had both moderate systemic hypertension and stable angina pectoris." | 5.07 | Comparison of diltiazem, nitrendipine, and their combination for systemic hypertension and stable angina pectoris. ( Andreyev, N; Andreyeva, T; Bichkov, I; Skutelis, A, 1991) |
| "The antianginal properties and the duration of action of two doses of felodipine, a dihydropyridine calcium antagonist with a vascular:myocardial potency ratio approximating 100:1, were investigated in 15 patients suffering from disabling effort angina pectoris with reproducible exercise tolerance." | 5.06 | Increased exercise tolerance and reduced electrocardiographic ischaemia 3 and 12 hours after oral felodipine in effort angina. ( Benemio, G; Boldrini, F; Gatteschi, C; Guerrieri, M; Pollavini, G; Porcellati, C; Verdecchia, P, 1989) |
| "We studied the effects of adding felodipine to beta-adrenoceptor blockade on haemodynamics and exercise capacity in 14 patients with stable angina pectoris using a placebo controlled double-blind crossover protocol." | 5.06 | Effects of felodipine on haemodynamics and exercise capacity in patients with angina pectoris. ( Routledge, PA; Sheridan, DJ; Sheridan, JV; Thomas, P, 1987) |
| "The effects of felodipine on haemodynamics and exercise capacity have been studied in patients with angina pectoris." | 5.06 | Felodipine in ischaemic heart disease. ( Sheridan, DJ; Sheridan, JV; Thomas, P, 1987) |
| "To investigate the antianginal efficacy, duration of action and tolerability of 2 doses of the new calcium antagonist felodipine, 15 patients (14 men and 1 woman, mean age 62 years) with stable exertional angina pectoris and angiographically demonstrated coronary artery disease were randomly given felodipine, 5 and 10 mg, and placebo on 3 different days." | 5.06 | Acute effects of felodipine in exertional angina pectoris. ( Ceschia, G; Pandullo, C; Pivotti, F; Pollavini, G; Scardi, S, 1988) |
| " As the first dihydropyridine available for use in the United States, nifedipine controls angina and hypertension with minimal depression of cardiac function." | 4.77 | Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications. ( Katz, AM; Leach, NM, 1987) |
| "To examine the antianginal and antihypertensive efficacy of nitrendipine, a new calcium channel blocking agent, 25 patients with chronic stable angina pectoris (NYHA I-III) and systemic hypertension underwent cardiac catheterization and treadmill exercise tests." | 3.67 | Acute and chronic effects of nitrendipine on hemodynamics and myocardial ischemia in patients with combined angina pectoris and hypertension. ( Arendt, RM; Hauck, R; Schmoeckel, M; Schultheiss, HP, 1988) |
| "Felodipine has antianginal effects but these are limited and seem less than those of other related compounds." | 2.66 | The effects of treatment with felodipine as a single agent in coronary artery disease. ( Chan-Wah-Hak, NS; Jennings, K; Metcalfe, MJ, 1989) |
| "Nitrendipine is a newly-developed calcium channel blocker derived from the dehydropyridine series which, according to experimental studies, affects marked dilation of the peripheral and coronary vessels." | 2.66 | [Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study]. ( Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W, 1985) |
| "RWJ 26629 was more potent than cromakalim and had a maximal activity greater than the calcium channel blockers." | 1.29 | RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent. ( Falotico, R; Giardino, EC; Katz, LB; Moore, JB; Salata, JJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JW | 1 |
| Leithäuser, B | 1 |
| Jung, F | 1 |
| Rutsch, W | 1 |
| Schmutzler, H | 1 |
| Katz, LB | 1 |
| Giardino, EC | 1 |
| Salata, JJ | 1 |
| Moore, JB | 1 |
| Falotico, R | 1 |
| Dhein, S | 1 |
| Salameh, A | 1 |
| Berkels, R | 1 |
| Klaus, W | 1 |
| Andreyev, N | 1 |
| Bichkov, I | 1 |
| Skutelis, A | 1 |
| Andreyeva, T | 1 |
| Schmoeckel, M | 1 |
| Arendt, RM | 1 |
| Hauck, R | 1 |
| Schultheiss, HP | 1 |
| Metcalfe, MJ | 1 |
| Chan-Wah-Hak, NS | 1 |
| Jennings, K | 1 |
| Verdecchia, P | 1 |
| Gatteschi, C | 1 |
| Benemio, G | 1 |
| Guerrieri, M | 1 |
| Boldrini, F | 1 |
| Pollavini, G | 2 |
| Porcellati, C | 1 |
| Sheridan, JV | 2 |
| Thomas, P | 2 |
| Routledge, PA | 1 |
| Sheridan, DJ | 2 |
| Brügmann, U | 1 |
| Blasini, R | 1 |
| Reiniger, G | 1 |
| Rudolph, W | 1 |
| Katz, AM | 1 |
| Leach, NM | 1 |
| Scardi, S | 1 |
| Pandullo, C | 1 |
| Pivotti, F | 1 |
| Ceschia, G | 1 |
2 reviews available for nitrendipine and Angor Pectoris
| Article | Year |
|---|---|
Dual mode of action of dihydropyridine calcium antagonists: a role for nitric oxide.
Topics: Angina Pectoris; Animals; Calcium; Clinical Trials as Topic; Dihydropyridines; Humans; Hypertension; | 1999 |
Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications.
Topics: Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Hemod | 1987 |
9 trials available for nitrendipine and Angor Pectoris
| Article | Year |
|---|---|
Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition.
Topics: Administration, Sublingual; Adult; Angina Pectoris; Blood Pressure; Carbolines; Cardiovascular Disea | 2008 |
Comparison of the acute hemodynamic effects of nifedipine with nitrendipine and a study of the electrophysiological effects of nitrendipine in man.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Electrocardiography; El | 1984 |
Comparison of diltiazem, nitrendipine, and their combination for systemic hypertension and stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Diltiazem; Double-Blind Method; Drug Therapy, Combinat | 1991 |
The effects of treatment with felodipine as a single agent in coronary artery disease.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Administration Sch | 1989 |
Increased exercise tolerance and reduced electrocardiographic ischaemia 3 and 12 hours after oral felodipine in effort angina.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Coronary Circulation; Electrocardiography; Exerc | 1989 |
Effects of felodipine on haemodynamics and exercise capacity in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Exercise Test; Felodipi | 1987 |
[Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study].
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind | 1985 |
Felodipine in ischaemic heart disease.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Clinical Trials as Topic; Coronary Disease; D | 1987 |
Acute effects of felodipine in exertional angina pectoris.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Exercise Test; Felod | 1988 |
2 other studies available for nitrendipine and Angor Pectoris
| Article | Year |
|---|---|
RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent.
Topics: Angina Pectoris; Animals; Antihypertensive Agents; Benzopyrans; Bronchoconstriction; Calcium Channel | 1993 |
Acute and chronic effects of nitrendipine on hemodynamics and myocardial ischemia in patients with combined angina pectoris and hypertension.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Exercise Test; Female; Hemodynamics; Humans; Hyperte | 1988 |