Page last updated: 2024-11-01

nitrendipine and Alloxan Diabetes

nitrendipine has been researched along with Alloxan Diabetes in 9 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"This study investigates the efficacy of late intervention with the calcium channel blockers (CCBs) nitrendipine and nisoldipine in preventing development of albuminuria and glomerular hypertrophy in experimental diabetes."3.70Effect of nitrendipine and nisoldipine on renal structure and function in long-term experimental diabetes in rats. ( Flyvbjerg, A; Grønbaek, H; Nielsen, B; Osterby, R, 2000)
"Nitrendipine treatment was unable to prevent increased GBM in diabetic SHR."1.30Effect of the calcium channel blocker nitrendipine in normotensive and spontaneously hypertensive, diabetic rats on kidney morphology and urinary albumin excretion. ( Flyvbjerg, A; Grønbaek, H; Nielsen, B; Osterby, R, 1999)
"Enalapril treatment (5 mg/kg/day, n = 11) or felodipine (30 mg/kg/day, n = 11) reduced systolic blood pressure to a comparable degree."1.27Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat. ( Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M, 1987)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Armenia, A2
Munavvar, AS1
Abdullah, NA3
Helmi, A1
Johns, EJ3
Sattar, MA2
Khan, MA2
Kato, S1
Ishida, H1
Tsuura, Y1
Okamoto, Y1
Tsuji, K1
Horie, M1
Okada, Y1
Seino, Y1
Nielsen, B2
Grønbaek, H2
Osterby, R2
Flyvbjerg, A2
Lee, SL2
Dhalla, NS2
Ostadalova, I1
Kolar, F1
Jackson, B1
Cubela, R1
Debrevi, L1
Whitty, M1
Johnston, CI1

Other Studies

9 other studies available for nitrendipine and Alloxan Diabetes

ArticleYear
The contribution of adrenoceptor subtype(s) in the renal vasculature of diabetic spontaneously hypertensive rats.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Animals; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Res

2004
Alpha1A- and alpha1D-adrenoceptors are the major functional subtypes of renal alpha1-adrenoceptors in streptozotocin-induced diabetic and normal Sprague-Dawley rats.
    Autonomic & autacoid pharmacology, 2008, Volume: 28, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Diabetes Mellitus, Expe

2008
Functional subtypes of renal alpha1-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:5

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Clonidine; D

2008
Increased calcium-channel currents of pancreatic beta cells in neonatally streptozocin-induced diabetic rats.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:11

    Topics: Animals; Animals, Newborn; Barium; Calcium Channels; Cells, Cultured; Diabetes Mellitus, Experimenta

1994
Effect of the calcium channel blocker nitrendipine in normotensive and spontaneously hypertensive, diabetic rats on kidney morphology and urinary albumin excretion.
    Journal of hypertension, 1999, Volume: 17, Issue:7

    Topics: Albuminuria; Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Hypertension; Kidne

1999
Effect of nitrendipine and nisoldipine on renal structure and function in long-term experimental diabetes in rats.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:2

    Topics: Albuminuria; Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Ex

2000
Ca(2+)-channels and adrenoceptors in diabetic skeletal muscle.
    Biochemical and biophysical research communications, 1992, Apr-15, Volume: 184, Issue:1

    Topics: Animals; Calcium Channels; Diabetes Mellitus, Experimental; Dihydroalprenolol; Kinetics; Male; Muscl

1992
Alterations in Ca(2+)-channels during the development of diabetic cardiomyopathy.
    Molecular and cellular biochemistry, 1992, Feb-12, Volume: 109, Issue:2

    Topics: Animals; Blood Glucose; Brain; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cardiomyopat

1992
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Expe

1987