nitrendipine has been researched along with Alcoholism in 10 studies
Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Excerpt | Relevance | Reference |
---|---|---|
"Mice which were withdrawal seizure prone showed a markedly greater severity of the ethanol-withdrawal syndrome, and also showed a significantly greater up-regulation of binding sites for [3H]nitrendipine with no significant difference in binding affinity." | 1.28 | Genetic regulation of dihydropyridine-sensitive calcium channels in brain may determine susceptibility to physical dependence on alcohol. ( Brennan, CH; Crabbe, J; Littleton, JM, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (40.00) | 18.7374 |
1990's | 6 (60.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Guppy, LJ | 4 |
Littleton, JM | 7 |
Goto, M | 1 |
Lemasters, JJ | 1 |
Thurman, RG | 1 |
Crabbe, JC | 1 |
Brennan, CH | 3 |
Crabbe, J | 1 |
Hudspith, MJ | 1 |
Charles, S | 1 |
Harper, JC | 1 |
Kril, JJ | 1 |
Gundlach, AL | 1 |
Dodd, PR | 1 |
Johnston, GA | 1 |
Harper, CG | 1 |
Dolin, SJ | 1 |
Little, HJ | 1 |
10 other studies available for nitrendipine and Alcoholism
Article | Year |
---|---|
Binding characteristics of the calcium channel antagonist [3H]-nitrendipine in tissues from ethanol-dependent rats.
Topics: Alcoholism; Animals; Calcium Channels; Cerebral Cortex; Male; Muscle, Skeletal; Myocardium; Nitrendi | 1994 |
The time course of up-regulation and down-regulation of dihydropyridine binding sites during the development of physical dependence on ethanol.
Topics: Alcoholism; Animals; Calcium Channels; Calcium Channels, L-Type; Cerebral Cortex; Down-Regulation; H | 1994 |
Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat.
Topics: Alcoholism; Animals; Calcium; Calcium Channels; Female; Kinetics; Kupffer Cells; Membrane Potentials | 1993 |
Time course and genetic variation in the regulation of calcium channel antagonist binding sites in rodent tissues during the induction of ethanol physical dependence and withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Calcium Channels; Cerebral Cortex; Down-Regulation | 1995 |
Damaging effects of the calcium paradox are reduced in isolated hearts from ethanol-dependent rats: paradoxic effects of dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Genetic regulation of dihydropyridine-sensitive calcium channels in brain may determine susceptibility to physical dependence on alcohol.
Topics: Alcoholism; Animals; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; | 1990 |
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Genetic up-regulation of calcium channels in a cellular model of ethanol dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Cortical dihydropyridine binding sites are unaltered in human alcoholic brain.
Topics: Alcoholism; Cerebral Cortex; Dihydropyridines; Humans; Isradipine; Male; Middle Aged; Nitrendipine; | 1989 |
Are changes in neuronal calcium channels involved in ethanol tolerance?
Topics: Alcoholism; Animals; Behavior, Animal; Brain; Calcium Channels; Dose-Response Relationship, Drug; Dr | 1989 |