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nitrazepam and Sleep Wake Disorders

nitrazepam has been researched along with Sleep Wake Disorders in 22 studies

Nitrazepam: A benzodiazepine derivative used as an anticonvulsant and hypnotic.
nitrazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).

Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.

Research Excerpts

ExcerptRelevanceReference
"Brotizolam 0."2.65Comparative studies on the efficacy of brotizolam and nitrazepam: a multi-centre study. ( Findeisen, P; Lohmann, H; von Delbrück, O, 1983)
" The results indicate that zopiclone is an active hypnotic compound, comparable in its effects to those of nitrazepam, the higher dosage being best adapted to the type of patients included in the study."2.65Comparison of nitrazepam and zopiclone in psychiatric patients. ( Brun, JP; Dreyfus, JF; Pull, CB, 1982)
"Fifty-two male PTSD outpatients on stable combination treatment with SSRI and benzodiazepines, with persistent sleep disturbances not responding to prescription of zolpidem, flurazepam, nitrazepam, promazine, and levopromazine, were assessed for sleep disturbances improvements after prescription of quetiapine in the evening."1.72Quetiapine Add-On Therapy May Improve Persistent Sleep Disturbances in Patients with PTSD on Stabile Combined SSRI and Benzodiazepine Combination: A One-Group Pretest-Posttest Study. ( Karlović, D; Ljubičić Bistrović, I; Ljubičić, R; Matošić, A; Peitl, V; Vilibić, M; Vlatković, S; Živković, M, 2022)
"Nitrazepam was given only when the children had fever and almost exclusively in children with a high risk of recurrence (less than 12 months of age at first convulsion; atypical convulsion; one or several previous convulsions)."1.27Intermittent treatment of febrile convulsions with nitrazepam. ( David, PC; Geoffroy, G; Larbrisseau, A; Masson, P; Vanasse, M, 1984)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199019 (86.36)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's0 (0.00)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Vilibić, M1
Peitl, V1
Živković, M1
Vlatković, S1
Ljubičić Bistrović, I1
Ljubičić, R1
Matošić, A1
Karlović, D1
Tokunaga, S1
Takeda, Y1
Shinomiya, K1
Hirase, M1
Kamei, C1
Frithz, G1
Groppi, W1
Werner, V1
Diehl, LW1
Lohmann, H1
von Delbrück, O2
Findeisen, P1
Vanasse, M1
Masson, P1
Geoffroy, G1
Larbrisseau, A1
David, PC1
Nagel, C1
Lichterfeld, A1
Pull, CB1
Dreyfus, JF1
Brun, JP1
Borbély, AA2
Neuhaus, HU1
Mattmann, P1
Waser, PG1
Tsivil'ko, MA1
Shinaev, NN1
Volkov, NP1
Brodersen, PE1
Mikkelsen, BO1
Viukari, M1
Linnoila, M1
Aalto, U1
Singer, K1
Lo, CW1
Tam, YK1
Hartelius, H1
Larsson, AK1
Lepp, M1
Malm, U1
Arvidsson, A1
Dahlström, H1
Fassolt, A1
Nassr, DG1
Moldofsky, H1
Tullis, C1
Quance, G1
Lue, FA1
Greenblatt, DJ1
Shader, RI1
Vol'f, MSh1
Prokudin, VN1
Iurkova, IA1
Konagaya, K1
Kawasumi, S1
Sato, K1
Takao, K1
Malpas, A1
Legg, NJ1
Scott, DF1

Reviews

3 reviews available for nitrazepam and Sleep Wake Disorders

ArticleYear
[The state of psychopharmacotherapy in geriatrics 2].
    Therapie der Gegenwart, 1980, Volume: 119, Issue:12

    Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D

1980
Drug therapy. Benzodiazepines (second of two parts).
    The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23

    Topics: Affective Symptoms; Alcoholism; Analgesia; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiet

1974
[Modification of sleep by hypnotics].
    Schweizerische medizinische Wochenschrift, 1973, Nov-10, Volume: 103, Issue:45

    Topics: Barbiturates; Benzazepines; Chloral Hydrate; Electroencephalography; Glutethimide; Humans; Hypnotics

1973

Trials

10 trials available for nitrazepam and Sleep Wake Disorders

ArticleYear
Temazepam versus nitrazepam: a comparative trial in the treatment of sleep disturbances.
    The Journal of international medical research, 1981, Volume: 9, Issue:5

    Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nitra

1981
Comparative studies on the efficacy of brotizolam and nitrazepam: a multi-centre study.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 2

    Topics: Adolescent; Adult; Aged; Azepines; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Fe

1983
Comparison of nitrazepam and zopiclone in psychiatric patients.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 2

    Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Clinical Trials as Topic; Double-Blind Method; Emotio

1982
[Treatment of sleep disorders with flurazepam (Dalmadorm), nitrazepam (Mogadon), and allypropymal. A controlled clinical investigation].
    Ugeskrift for laeger, 1976, Jan-05, Volume: 138, Issue:2

    Topics: Anti-Anxiety Agents; Barbiturates; Clinical Trials as Topic; Flurazepam; Humans; Nitrazepam; Sleep W

1976
Efficacy and side effects of flurazepam, fosazepam, and nitrazepam as sleeping aids in psychogeriatric patients.
    Acta psychiatrica Scandinavica, 1978, Volume: 57, Issue:1

    Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Drug Evaluation; Female; Flurazepam;

1978
Comparative evaluation of hypnotic efficacy of flunitrazepam in psychiatric in-patients.
    Acta psychiatrica Scandinavica, 1978, Volume: 57, Issue:5

    Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Fe

1978
A controlled long-term study of flunitrazepam, nitrazepam and placebo, with special regard to withdrawal effects.
    Acta psychiatrica Scandinavica, 1978, Volume: 58, Issue:1

    Topics: Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Dr

1978
[The clinical efficiency of some hypnotics in cases of preoperative sleeping disturbances (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1975, Aug-12, Volume: 64, Issue:32

    Topics: Adult; Clinical Trials as Topic; Diazepam; Drug Combinations; Drug Therapy, Combination; Female; Glu

1975
[Comparison of the effects of minor tranquilizers in preoperative sleep disorders by double blind controlled study].
    Masui. The Japanese journal of anesthesiology, 1972, Volume: 21, Issue:9

    Topics: Azepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Nitrazepam; Placebos; Preoperati

1972
Effects of hypnotics on anxious patients.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:0

    Topics: Administration, Oral; Adult; Alpha Rhythm; Amobarbital; Anxiety Disorders; Clinical Trials as Topic;

1974

Other Studies

9 other studies available for nitrazepam and Sleep Wake Disorders

ArticleYear
Quetiapine Add-On Therapy May Improve Persistent Sleep Disturbances in Patients with PTSD on Stabile Combined SSRI and Benzodiazepine Combination: A One-Group Pretest-Posttest Study.
    Psychiatria Danubina, 2022,Summer, Volume: 34, Issue:2

    Topics: Antipsychotic Agents; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; Male; Methotrime

2022
Effects of some H1-antagonists on the sleep-wake cycle in sleep-disturbed rats.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:2

    Topics: Animals; Chlorpheniramine; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Electr

2007
Intermittent treatment of febrile convulsions with nitrazepam.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1984, Volume: 11, Issue:3

    Topics: Akathisia, Drug-Induced; Ataxia; Child; Follow-Up Studies; Humans; Nitrazepam; Recurrence; Risk; Sei

1984
Efficacy and acceptability of brotizolam in the elderly.
    British journal of clinical pharmacology, 1983, Volume: 16 Suppl 2

    Topics: Aged; Azepines; Drug Tolerance; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nitrazep

1983
[Long term recording of motor activity: its use in research and clinical situations].
    Schweizerische medizinische Wochenschrift, 1981, May-23, Volume: 111, Issue:21

    Topics: Adult; Aged; Circadian Rhythm; Computers; Female; Humans; Male; Middle Aged; Minicomputers; Motor Ac

1981
[Comparative study of effects of ivadal and rodedorm in insomnia in structure of borderline mental diseases].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:2

    Topics: Borderline Personality Disorder; GABA Agonists; GABA Modulators; Humans; Nitrazepam; Pyridines; Slee

2001
Paradoxical response to nitrazepam in a patient with hypersomnia secondary to nocturnal myoclonus.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:2

    Topics: Adult; Disorders of Excessive Somnolence; Humans; Male; Myoclonus; Nitrazepam; Sleep Wake Disorders

1986
Nitrazepam for periodic movements in sleep (sleep-related myoclonus).
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1986, Volume: 13, Issue:1

    Topics: Arousal; Attention; Drug Evaluation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myoclonus

1986
[The place of nitrazepam in the complex treatment of epilepsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:11

    Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Child; Child, Preschool; Drug Synergism; Drug Ther

1973