nitrazepam has been researched along with Pregnancy in 22 studies
Nitrazepam: A benzodiazepine derivative used as an anticonvulsant and hypnotic.
nitrazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)." | 7.71 | A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002) |
| "The very large doses of nitrazepam used for suicide attempt during pregnancy resulted in a high rate of CAs which may be connected with the disruption of protein metabolism in fetal mesenchyma." | 3.76 | Congenital abnormalities in children of 43 pregnant women who attempted suicide with large doses of nitrazepam. ( Acs, N; Bánhidy, F; Czeizel, AE; Gidai, J, 2010) |
| "To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)." | 3.71 | A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002) |
| "It is reported on an intoxication with nitrazepam at the end of pregnancy." | 3.68 | [Drug poisoning in the 39th week of pregnancy--a case report]. ( Heinze, I; Treu, TM, 1990) |
| "Knowledge of the pharmacokinetic properties of the benzodiazepines is playing an increasingly important role in their use during pregnancy, labour and lactation." | 2.36 | Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations. ( Kanto, JH, 1982) |
| "Nitrazepam was found to produce various types of malformations, i." | 1.28 | Teratogenic effects of nitrazepam in rats. ( Nakagawa, M; Sakai, T; Takeno, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gidai, J | 1 |
| Acs, N | 1 |
| Bánhidy, F | 1 |
| Czeizel, AE | 2 |
| Zupkó, I | 1 |
| Jánossy, K | 1 |
| Maul, K | 1 |
| Márki, A | 1 |
| Falkay, G | 1 |
| Kanto, JH | 1 |
| Olive, G | 1 |
| Rey, E | 1 |
| Saito, H | 2 |
| Kobayashi, H | 2 |
| Takeno, S | 5 |
| Sakai, T | 5 |
| Meut, C | 1 |
| Bavoux, F | 1 |
| Cynober, E | 1 |
| Lebrun, F | 1 |
| Hirano, Y | 1 |
| Kitamura, A | 1 |
| Eros, E | 1 |
| Rockenbauer, M | 1 |
| Sorensen, HT | 1 |
| Olsen, J | 1 |
| Fox, KA | 1 |
| Guerriero, FJ | 1 |
| Speight, AN | 1 |
| Reith, H | 1 |
| Schäfer, H | 1 |
| Kangas, L | 2 |
| Kanto, J | 2 |
| Mansikka, M | 1 |
| Erkkola, R | 1 |
| Nakagawa, M | 1 |
| Treu, TM | 1 |
| Heinze, I | 1 |
| Ishii, H | 1 |
| Fujii, T | 1 |
| Ohtaki, Y | 1 |
| Nakanishi, H | 1 |
| Morimoto, S | 1 |
| Hayashi, K | 1 |
| Yamamoto, N | 1 |
| Khubenova, A | 1 |
| Popov, A | 1 |
| Makaveeva, V | 1 |
| Greenblatt, DJ | 1 |
| Shader, RI | 1 |
| Browne, TR | 1 |
| Penry, JK | 1 |
| Tanayama, S | 1 |
| Momose, S | 1 |
| Kanai, Y | 1 |
| Shirakawa, Y | 1 |
5 reviews available for nitrazepam and Pregnancy
| Article | Year |
|---|---|
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Hum | 1982 |
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation].
Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; | 1983 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; | 1979 |
Drug therapy. Benzodiazepines (second of two parts).
Topics: Affective Symptoms; Alcoholism; Analgesia; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiet | 1974 |
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec | 1973 |
17 other studies available for nitrazepam and Pregnancy
| Article | Year |
|---|---|
Congenital abnormalities in children of 43 pregnant women who attempted suicide with large doses of nitrazepam.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anti-Anxiety Agents; Dose-Response Relationship, Dru | 2010 |
Alpha-adrenergic blockade: a possible mechanism of tocolytic action of certain benzodiazepines in a postpartum rat model in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; | 2003 |
Fetal toxicity of benzodiazepines in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Clonazepam; Diazepam; F | 1984 |
Necrotizing enterocolitis in a newborn: maternal psychotropic drugs suspected.
Topics: Adult; Biperiden; Chlorpromazine; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female | 1994 |
Comparative developmental toxicity and metabolism of nitrazepam in rats and mice.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Embryo, Mammalian; Femal | 1993 |
A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Alprazolam; Anti-Anxiety Agents; Antico | 2002 |
Effect of benzodiazepines on age of vaginal perforation and first estrus in mice.
Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Estrus; Female; Mice; Nitrazepam; Prazepam | 1978 |
Floppy-infant syndrome and maternal diazepam and/or nitrazepam.
Topics: Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Maternal-Fetal Exchange; | 1977 |
Nitrazepam premedication for minor surgery.
Topics: Administration, Oral; Female; Humans; Minor Surgical Procedures; Nitrazepam; Preanesthetic Medicatio | 1977 |
Transfer of nitrazepam across the human placenta.
Topics: Adolescent; Adult; Female; Humans; Maternal-Fetal Exchange; Nitrazepam; Placenta; Pregnancy | 1977 |
Involvement of the intestinal microflora in nitrazepam-induced teratogenicity in rats and its relationship to nitroreduction.
Topics: Animals; Cecum; Colony Count, Microbial; Feces; Female; Metabolic Clearance Rate; Nitrazepam; Nitror | 1991 |
Teratogenic effects of nitrazepam in rats.
Topics: Animals; Female; Gestational Age; Hemorrhage; Necrosis; Nitrazepam; Pregnancy; Rats; Rats, Inbred St | 1990 |
[Drug poisoning in the 39th week of pregnancy--a case report].
Topics: Adult; Female; Humans; Nitrazepam; Obstetric Labor Complications; Pregnancy; Pregnancy Trimester, Th | 1990 |
In vivo and in vitro studies on fetal toxicity of benzodiazepines in rats.
Topics: Animals; Anti-Anxiety Agents; Diazepam; Embryonic and Fetal Development; Female; Fetal Blood; Fetus; | 1986 |
Alterations in the thermic response to chlorpromazine in rats exposed prenatally to central nervous system depressants.
Topics: Animals; Body Temperature; Central Nervous System Depressants; Chlorpromazine; Drug Interactions; Et | 1986 |
[Acute poisoning and pregnancy].
Topics: Acute Disease; Adolescent; Adult; Female; Humans; Mushroom Poisoning; Nitrazepam; Phenobarbital; Pre | 1986 |
Metabolism of 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)-(1,4)benzodiazepine (D-40TA), a new central depressant. IV. Placental transfer and excretion in milk in rats.
Topics: Adipose Tissue; Adrenal Glands; Amination; Amniotic Fluid; Animals; Animals, Newborn; Autoradiograph | 1974 |