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nitrazepam and Abnormalities, Drug-Induced

nitrazepam has been researched along with Abnormalities, Drug-Induced in 4 studies

Nitrazepam: A benzodiazepine derivative used as an anticonvulsant and hypnotic.
nitrazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)."7.71A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002)
"The very large doses of nitrazepam used for suicide attempt during pregnancy resulted in a high rate of CAs which may be connected with the disruption of protein metabolism in fetal mesenchyma."3.76Congenital abnormalities in children of 43 pregnant women who attempted suicide with large doses of nitrazepam. ( Acs, N; Bánhidy, F; Czeizel, AE; Gidai, J, 2010)
"To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)."3.71A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gidai, J1
Acs, N1
Bánhidy, F1
Czeizel, AE2
Saito, H1
Kobayashi, H1
Takeno, S2
Sakai, T2
Hirano, Y1
Kitamura, A1
Eros, E1
Rockenbauer, M1
Sorensen, HT1
Olsen, J1

Other Studies

4 other studies available for nitrazepam and Abnormalities, Drug-Induced

ArticleYear
Congenital abnormalities in children of 43 pregnant women who attempted suicide with large doses of nitrazepam.
    Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anti-Anxiety Agents; Dose-Response Relationship, Dru

2010
Fetal toxicity of benzodiazepines in rats.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Clonazepam; Diazepam; F

1984
Comparative developmental toxicity and metabolism of nitrazepam in rats and mice.
    Toxicology and applied pharmacology, 1993, Volume: 121, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Embryo, Mammalian; Femal

1993
A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 2002, Mar-10, Volume: 101, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Alprazolam; Anti-Anxiety Agents; Antico

2002