nitrates has been researched along with Substance-Related Disorders in 26 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Substance-Related Disorders: Disorders related to substance use or abuse.
Excerpt | Relevance | Reference |
---|---|---|
"Nitrates are presently used in the therapy for angina pectoris." | 4.77 | Nitrate therapy for angina pectoris. Current concepts about mechanism of action and evaluation of currently available preparations. ( Corwin, S; Reiffel, JA, 1985) |
"Methemoglobinemia is a rare pathology that results from the oxidation of iron in the hemoglobin molecule." | 1.38 | Two cases of acquired methemoglobinemia. ( Bergmans, D; Hall, A; Schnabel, R; Stessel, B, 2012) |
"Vasodilator treatment of congestive heart failure has provided an important new role for long-acting nitrates." | 1.26 | Nitrate tolerance and dependence. A critical assessment. ( Abrams, J, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (42.31) | 18.7374 |
1990's | 5 (19.23) | 18.2507 |
2000's | 4 (15.38) | 29.6817 |
2010's | 6 (23.08) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kamour, A | 1 |
Yardley, R | 1 |
Longshaw, M | 1 |
Stuart, J | 1 |
Dickerson, F | 1 |
Stallings, C | 1 |
Origoni, A | 1 |
Katsafanas, E | 1 |
Sweeney, K | 1 |
Khushalani, S | 1 |
Yolken, R | 1 |
Santos, GM | 1 |
Coffin, PO | 1 |
Das, M | 1 |
Matheson, T | 1 |
DeMicco, E | 1 |
Raiford, JL | 1 |
Vittinghoff, E | 1 |
Dilley, JW | 1 |
Colfax, G | 1 |
Herbst, JH | 1 |
Underwood, B | 1 |
Fox, K | 1 |
Manogue, M | 1 |
Wilkerson, RG | 1 |
Hall, A | 1 |
Stessel, B | 1 |
Bergmans, D | 1 |
Schnabel, R | 1 |
Lubman, DI | 1 |
Hides, L | 1 |
Yücel, M | 1 |
Semple, SJ | 1 |
Zians, J | 1 |
Strathdee, SA | 1 |
Patterson, TL | 1 |
Abrams, J | 2 |
Martynov, AI | 1 |
Belinskaia, TF | 1 |
Frömmel, H | 1 |
Morabia, A | 1 |
Dudley, MJ | 1 |
Solomon, T | 1 |
Boesgaard, S | 1 |
Robins, AG | 1 |
Dew, MA | 1 |
Kingsley, LA | 1 |
Becker, JT | 1 |
McFarland, W | 2 |
Kellogg, TA | 1 |
Dilley, J | 1 |
Katz, MH | 2 |
Waldo, CR | 1 |
MacKellar, D | 1 |
Valleroy, LA | 1 |
Ponnappan, U | 1 |
Soderberg, LS | 1 |
Aronow, WS | 1 |
Reichek, N | 1 |
Mathew, RJ | 1 |
Wilson, WH | 1 |
Tant, SR | 1 |
Corwin, S | 1 |
Reiffel, JA | 1 |
Frishman, WH | 1 |
Buge, A | 1 |
Rancurel, G | 1 |
Poisson, M | 1 |
Dechy, H | 1 |
Cambier, J | 1 |
Mason, M | 1 |
Dairou, R | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Treatment With Lorcaserin for Cocaine Use: The TLC Study[NCT03192995] | Phase 2 | 22 participants (Actual) | Interventional | 2018-01-01 | Terminated (stopped due to FDA alert regarding study drug safety) | ||
Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM): Adaptation of the Personalized Cognitive Counseling (PCC) Intervention[NCT01279044] | Phase 1/Phase 2 | 385 participants (Actual) | Interventional | 2007-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
To evaluate the adherence of lorcaserin vs. placebo, the investigators measured adherence as the frequency of taking the study drug as measured by the number of MEMS cap openings (wireless medication monitoring devices that record each opening as a real-time medication event). Cumulative percent adherence was calculated by dividing the frequency of openings at a given time point divided by the number of days since baseline. (NCT03192995)
Timeframe: 12 weeks
Intervention | percent adherence (Mean) |
---|---|
Experimental | 51.6 |
Control | 66.2 |
To determine the feasibility of retaining individuals on lorcaserin vs. placebo, the investigators have calculated the mean weekly percentage of follow-up visits of those randomized in the study (NCT03192995)
Timeframe: 12 weeks
Intervention | mean percent of visit retention (Mean) | |
---|---|---|
Treatment Group | Control Group | |
Mean Percent of Weekly Follow-up Visits by Treatment and Control Arms | 83 | 81 |
The outcome measure determines the proportion of self-reported past week cocaine use by Time-Line-Follow-back (TLFB) among lorcaserin and placebo groups at Baseline and at 12 weeks. (NCT03192995)
Timeframe: 12 weeks
Intervention | Participants (Count of Participants) | |
---|---|---|
Proportion of self-reported weekly cocaine use by Time-Line-Follow-Up (TLFU) at baseline | Proportion of self-reported weekly cocaine use by TLFU at Week 12 | |
Control | 6 | 6 |
Experimental | 12 | 7 |
The outcome measure determines the proportion of urine-positive samples with cocaine positivity among lorcaserin and placebo groups at Baseline and at Week 12 (NCT03192995)
Timeframe: Week 12
Intervention | Participants (Count of Participants) | |
---|---|---|
Urine positive samples with cocaine use at baseline | Urine positive samples with cocaine use at Week 12 | |
Control | 0 | 1 |
Treatment | 8 | 7 |
"The outcome measure data shows the rate of change in the mean value of the number of condom-protected anal intercourse (UAI) events. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints.~Serodiscordant defined as having partner of discordant or of unknown HIV serostatus." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Self reported behavior in past 3 months (Number) | |||
---|---|---|---|---|
Mean number of events at baseline | Mean number of events at 3 months | Mean number of events at 6 months | Rate of change in mean value of outcome over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 3.78 | 1.67 | 2.11 | 0.57 |
HIV Testing With Information Only | 2.83 | 2.13 | 1.29 | 0.44 |
"The outcome measure data shows the rate of change in the mean value of number of instertive unprotected anal intercourse (UAI) events. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Self reported behavior in past 3 months (Number) | |||
---|---|---|---|---|
Mean number of events at baseline | Mean number of events at 3 months | Mean number of events at 6 months | Rate of change in mean value over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 2.84 | 2.80 | 1.37 | 0.55 |
HIV Testing With Information Only | 2.44 | 1.32 | 1.14 | 0.41 |
"The outcome measure data shows the rate of change in the mean value of the number of receptive unprotected anal intercourse (UAI) events. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Self reported behavior in past 3 months (Number) | |||
---|---|---|---|---|
Mean number of events at baseline | Mean number of events at 3 months | Mean number of events at 6 months | Rate of change in mean value of outcome over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 1.39 | 0.61 | 0.45 | 0.31 |
HIV Testing With Information Only | 1.48 | 0.73 | 0.82 | 0.53 |
"The outcome measure data shows the rate of change in the mean value of number of serodiscordant unprotected anal intercourse events. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints.~Serodiscordant defined as having partner of discordant or of unknown HIV serostatus." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Events in past 3 months (Number) | |||
---|---|---|---|---|
Mean number of events at baseline | Mean number of events at 3 months | Mean number of events at 6 months | Rate of change in mean value of outcome over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 1.06 | 0.43 | 0.34 | 0.28 |
HIV Testing With Information Only | 1.13 | 0.49 | 0.55 | 0.47 |
"The outcome measure data shows the rate of change in the mean value in the number of total unprotected anal intercourse events over time. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Self reported events in past 3 months (Number) | |||
---|---|---|---|---|
Mean number at baseline | Mean number at 3 months | Mean number at 6 months | Rate of change in mean value of outcome over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 4.23 | 3.41 | 1.83 | 0.47 |
HIV Testing With Information Only | 3.91 | 2.05 | 1.96 | 0.45 |
"The outcome measure data shows the rate of change in the mean value of total unprotected anal intercourse partners over time. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Partners in past 3 months (Number) | |||
---|---|---|---|---|
Mean number of partners at baseline | Mean number of partners at 3 months | Mean number of partners at 6 months | Rate of change in mean value of outcome over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 2.71 | 1.54 | 1.27 | 0.46 |
HIV Testing With Information Only | 2.60 | 1.37 | 1.16 | 0.43 |
"The outcome measure data shows the rate of change in the mean value of total unprotected anal intercourse episodes with three most recent sex partners over time. Behaviors were self-reported at each study visit using during the past 3 months as the recall period. Study visits took place at baseline, 3 month, and 6 month timepoints." (NCT01279044)
Timeframe: Self-reported behavior during past 3 months
Intervention | Episodes in past 3 months (Number) | |||
---|---|---|---|---|
Mean number of episodes at baseline | Mean number of episodes at 3 months | Mean number of episodes at 6 months | Rate of change in mean value of outcome over time | |
HIV Testing With Adapted Personalized Cognitive Risk-reduction | 1.97 | 1.12 | 0.83 | 0.39 |
HIV Testing With Information Only | 2.31 | 1.11 | 1.20 | 0.52 |
4 reviews available for nitrates and Substance-Related Disorders
Article | Year |
---|---|
Inhalant misuse in youth: time for a coordinated response.
Topics: Administration, Inhalation; Adolescent; Adolescent Behavior; Aerosols; Alkanes; Australia; Female; H | 2006 |
Nitrate tolerance and dependence.
Topics: Ambulatory Care; Angina Pectoris; Animals; Cardiovascular Diseases; Dogs; Drug Tolerance; Heart Fail | 1980 |
Thiol compounds and organic nitrates.
Topics: Animals; Drug Interactions; Drug Tolerance; Hemodynamics; Nitrates; Substance-Related Disorders; Sul | 1995 |
Nitrate therapy for angina pectoris. Current concepts about mechanism of action and evaluation of currently available preparations.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Angina, Unstable; Animals; Coronary | 1985 |
22 other studies available for nitrates and Substance-Related Disorders
Article | Year |
---|---|
The Experience of a District General Hospital with a Large Outdoor Music Festival in England.
Topics: Emergency Medical Services; England; Holidays; Hospitals, District; Hospitals, General; Humans; Illi | 2017 |
Nitrated meat products are associated with suicide behavior in psychiatric patients.
Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Diet; Female; Humans; Male; Meat Products; Ment | 2019 |
Dose-response associations between number and frequency of substance use and high-risk sexual behaviors among HIV-negative substance-using men who have sex with men (SUMSM) in San Francisco.
Topics: Adult; Alcohol Drinking; Cocaine; Confidence Intervals; Cross-Sectional Studies; HIV Seronegativity; | 2013 |
Dose-response associations between number and frequency of substance use and high-risk sexual behaviors among HIV-negative substance-using men who have sex with men (SUMSM) in San Francisco.
Topics: Adult; Alcohol Drinking; Cocaine; Confidence Intervals; Cross-Sectional Studies; HIV Seronegativity; | 2013 |
Dose-response associations between number and frequency of substance use and high-risk sexual behaviors among HIV-negative substance-using men who have sex with men (SUMSM) in San Francisco.
Topics: Adult; Alcohol Drinking; Cocaine; Confidence Intervals; Cross-Sectional Studies; HIV Seronegativity; | 2013 |
Dose-response associations between number and frequency of substance use and high-risk sexual behaviors among HIV-negative substance-using men who have sex with men (SUMSM) in San Francisco.
Topics: Adult; Alcohol Drinking; Cocaine; Confidence Intervals; Cross-Sectional Studies; HIV Seronegativity; | 2013 |
Tobacco, alcohol and drug use among dental undergraduates at one English university in 1998 and 2008.
Topics: Alcohol Drinking; Amphetamine-Related Disorders; Anabolic Agents; Cross-Sectional Studies; England; | 2010 |
Getting the blues at a rock concert: a case of severe methaemoglobinaemia.
Topics: Enzyme Inhibitors; Ethanol; Female; Humans; Methemoglobinemia; Methylene Blue; Music; Nitrates; Oxim | 2010 |
Two cases of acquired methemoglobinemia.
Topics: Anti-Infective Agents; Antidotes; Dapsone; Female; HIV Infections; HIV-1; Humans; Male; Methemoglobi | 2012 |
Sexual marathons and methamphetamine use among HIV-positive men who have sex with men.
Topics: Adult; Alcohol-Related Disorders; Central Nervous System Stimulants; HIV Infections; Homosexuality, | 2009 |
Nitrate tolerance and dependence. A critical assessment.
Topics: Angina Pectoris; Animals; Dogs; Drug Tolerance; Heart Failure; Humans; Isosorbide Dinitrate; Nitrate | 1980 |
[Use of nitrates in clinical practice].
Topics: Angina Pectoris; Cardiovascular System; Electrocardiography; Heart Failure; Humans; Myocardial Infar | 1980 |
[Habituation to nitrates. A response to V. Wandner's paper "The Angina Pectoris Syndrome" in Z. ärztl. Fortbild. 73(1979), p. 58--At the same time a presentation of the current state of knowledge].
Topics: Angina Pectoris; Humans; Nitrates; Substance-Related Disorders | 1980 |
Poppers, Kaposi's sarcoma, and HIV infection: empirical example of a strong confounding effect?
Topics: Confounding Factors, Epidemiologic; HIV Infections; Humans; Nitrates; Odds Ratio; Pentanols; Prevale | 1995 |
A case of methaemoglobinaemia.
Topics: Adult; Emergency Service, Hospital; Female; Humans; Methemoglobinemia; Nitrates; Pentanols; Poisonin | 1993 |
Do homosexual and bisexual men who place others at potential risk for HIV have unique psychological profiles?
Topics: Adaptation, Psychological; Alcohol Drinking; Bisexuality; Cohort Studies; Health Education; Health K | 1997 |
Estimation of human immunodeficiency virus (HIV) seroincidence among repeat anonymous testers in San Francisco.
Topics: Adult; Black or African American; Black People; Confidence Intervals; Feasibility Studies; HIV Serop | 1997 |
Very young gay and bisexual men are at risk for HIV infection: the San Francisco Bay Area Young Men's Survey II.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adolescent; Adult; Age Factors; Amphetamines; Bisexual | 2000 |
Inflammatory macrophage nuclear factor-kappaB and proteasome activity are inhibited following exposure to inhaled isobutyl nitrite.
Topics: Administration, Inhalation; Animals; Butanes; Cysteine Endopeptidases; Cytotoxicity, Immunologic; De | 2001 |
Clinical use of nitrates. II. Nitrates in congestive heart failure.
Topics: Administration, Oral; Drug Evaluation; Heart Failure; Humans; Nitrates; Nitroglycerin; Ointments; Su | 1979 |
Long-acting nitrates in the treatment of angina pectoris.
Topics: Angina Pectoris; Delayed-Action Preparations; Erythrityl Tetranitrate; Hemodynamics; Humans; Isosorb | 1976 |
Regional cerebral blood flow changes associated with amyl nitrite inhalation.
Topics: Administration, Inhalation; Adult; Affect; Blood Pressure; Cerebrovascular Circulation; Homosexualit | 1989 |
Pharmacology of the nitrates in angina pectoris.
Topics: Administration, Oral; Administration, Topical; Angina Pectoris; Cheek; Chemical Phenomena; Chemistry | 1985 |
[Myoclonic encephalopathies induced by bismuth salts. 6 cases observed during long-term oral treatment].
Topics: Administration, Oral; Adult; Asthenia; Bismuth; Brain; Brain Diseases; Cognition Disorders; Confusio | 1974 |
[Letter: Myoclonic encephalopathy and bismuth salt poisoning].
Topics: Bismuth; Brain Diseases; Drug Synergism; Electroencephalography; Humans; Male; Mental Disorders; Mid | 1974 |