nitrates has been researched along with Sleep Apnea, Obstructive in 14 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin treatment of IH-exposed animals decreased blood pressure, blood glucose, and ROS and nitrite/nitrate levels, and increased vasodilation and capillary perfusion." | 5.35 | Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia. ( Bertuglia, S; Reiter, RJ, 2009) |
| "In conclusion, oxidative stress present in obesity is elevated by OSA and CPAP treatment can rise the levels of SO and can decrease serum nitrite/nitrates present in obese patients with OSA." | 3.74 | [Obstructive sleep apnea contribution to oxidative stress in obesity]. ( Ataíde, L; Bezerra, Ade A; Castro, CM; Franco, CM; Halpern, A; Lima, AM, 2008) |
| " The decrease in NO bioavailability and in erythrocyte deformability might contribute to explain the increased cardiovascular risk in OSAS subjects." | 1.42 | Nitric oxide metabolites and erythrocyte deformability in a group of subjects with obstructive sleep apnea syndrome. ( Caimi, G; Calandrino, V; Canino, B; Hopps, E; Lo Presti, R; Montana, M, 2015) |
| "Obesity and obstructive sleep apnea (OSA) are both associated with the prevalence of major cardiovascular illnesses and certain common factors they are considered responsible for, such as stress oxidative increase, sympathetic tonus and resistance to insulin." | 1.36 | Effects of nasal continuous positive airway pressure treatment on oxidative stress and adiponectin levels in obese patients with obstructive sleep apnea. ( Ataíde, L; Bezerra, Ade A; de Castro, CM; de Lima, AM; Franco, CM; Halpern, A, 2010) |
| "Subjects with moderate-to-severe hypoxemia had significantly lower ln-transformed NO metabolites (1." | 1.36 | Serum nitrite and nitrate levels in children with obstructive sleep-disordered breathing. ( Alexopoulos, E; Chaidas, K; Gougoura, S; Gourgoulianis, K; Kaditis, A; Karathanasi, A; Liakos, P; Ntamagka, G; Papathanasiou, AA; Zintzaras, E, 2010) |
| "Melatonin treatment of IH-exposed animals decreased blood pressure, blood glucose, and ROS and nitrite/nitrate levels, and increased vasodilation and capillary perfusion." | 1.35 | Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia. ( Bertuglia, S; Reiter, RJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Lao, M | 1 |
| Cheng, Y | 1 |
| Gao, X | 1 |
| Ou, Q | 1 |
| Canino, B | 1 |
| Hopps, E | 1 |
| Calandrino, V | 1 |
| Montana, M | 1 |
| Lo Presti, R | 1 |
| Caimi, G | 1 |
| Kapusuz Gencer, Z | 1 |
| Özkiriş, M | 1 |
| Göçmen, Y | 1 |
| Intepe, YS | 1 |
| Akin, I | 1 |
| Delibaş, N | 1 |
| Delibaşi, N | 1 |
| Saydam, L | 1 |
| Kerley, CP | 1 |
| Dolan, E | 1 |
| Cormican, L | 1 |
| Lima, AM | 1 |
| Franco, CM | 2 |
| Castro, CM | 1 |
| Bezerra, Ade A | 2 |
| Ataíde, L | 2 |
| Halpern, A | 2 |
| Alonso-Fernández, A | 1 |
| García-Río, F | 1 |
| Arias, MA | 1 |
| Hernanz, A | 1 |
| de la Peña, M | 1 |
| Piérola, J | 1 |
| Barceló, A | 1 |
| López-Collazo, E | 1 |
| Agustí, A | 1 |
| Bertuglia, S | 1 |
| Reiter, RJ | 1 |
| de Lima, AM | 1 |
| de Castro, CM | 1 |
| Kaditis, A | 1 |
| Alexopoulos, E | 1 |
| Ntamagka, G | 1 |
| Chaidas, K | 1 |
| Karathanasi, A | 1 |
| Gougoura, S | 1 |
| Papathanasiou, AA | 1 |
| Liakos, P | 1 |
| Zintzaras, E | 1 |
| Gourgoulianis, K | 1 |
| Bakker, JP | 1 |
| Neill, AM | 1 |
| Campbell, AJ | 1 |
| Del Ben, M | 1 |
| Fabiani, M | 1 |
| Loffredo, L | 1 |
| Polimeni, L | 1 |
| Carnevale, R | 1 |
| Baratta, F | 1 |
| Brunori, M | 1 |
| Albanese, F | 1 |
| Augelletti, T | 1 |
| Violi, F | 1 |
| Angelico, F | 1 |
| Teramoto, S | 1 |
| Kume, H | 1 |
| Matsuse, T | 1 |
| Ishii, T | 1 |
| Miyashita, A | 1 |
| Akishita, M | 1 |
| Toba, K | 1 |
| Ouchi, Y | 2 |
| Ohike, Y | 1 |
| Kozaki, K | 1 |
| Iijima, K | 1 |
| Eto, M | 1 |
| Kojima, T | 1 |
| Ohga, E | 1 |
| Santa, T | 1 |
| Imai, K | 1 |
| Hashimoto, M | 1 |
| Yoshizumi, M | 1 |
| Schulz, R | 1 |
| Seeger, W | 1 |
| Grimminger, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sleep Apnea cardioVascular Endpoints Study - Investigating the Effectiveness of Treatment With CPAP vs Standard Care in Reducing CV Morbidity and Mortality in Patients With Co-existing CV Disease and Moderate-severe Obstructive Sleep Apnea.[NCT00738179] | Phase 3 | 2,500 participants (Anticipated) | Interventional | 2008-09-30 | Active, not recruiting | ||
| Impact of Estrogen + Estradiol Receptor Alpha Modulator Therapy on Oxidative Stress in Post-menopausal Women With and Without Sleep Apnea[NCT03981341] | Phase 3 | 36 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | ||
| Impact of the Type of Interface in Neuromuscular Patients Treated With Nocturnal Noninvasive Ventilation: a Randomized Crossover Trial[NCT03458507] | 30 participants (Actual) | Interventional | 2018-05-28 | Completed | |||
| Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.[NCT02247167] | Phase 1/Phase 2 | 15 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for nitrates and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
The interaction among OSA, CPAP, and medications in patients with comorbid OSA and cardiovascular/cerebrovascular disease: a randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Aged; Cardiovascular Agents; Cardiovascular Diseases; Cerebrovascular D | 2022 |
Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea: a randomised trial.
Topics: Adult; Aged; Blood Pressure; Continuous Positive Airway Pressure; Dinoprost; Double-Blind Method; Hu | 2009 |
Nasal versus oronasal continuous positive airway pressure masks for obstructive sleep apnea: a pilot investigation of pressure requirement, residual disease, and leak.
Topics: Air Pressure; Body Mass Index; Breath Tests; Child; Child, Preschool; Continuous Positive Airway Pre | 2012 |
Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment.
Topics: Adult; Biomarkers; Brachial Artery; Continuous Positive Airway Pressure; Dinoprost; Female; Humans; | 2012 |
Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.
Topics: Adult; Aged; Arginine; Brachial Artery; Continuous Positive Airway Pressure; Endothelium, Vascular; | 2005 |
9 other studies available for nitrates and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Nitric oxide metabolites and erythrocyte deformability in a group of subjects with obstructive sleep apnea syndrome.
Topics: Adult; Aged; Erythrocyte Deformability; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; N | 2015 |
The correlation of serum levels of leptin, leptin receptor and NO x (NO 2 (-) and NO 3 (-)) in patients with obstructive sleep apnea syndrome.
Topics: Adolescent; Adult; Body Mass Index; Female; Humans; Leptin; Male; Middle Aged; Nitrates; Nitric Oxid | 2014 |
Dietary nitrate decreased blood pressure in obstructive sleep apnoea syndrome: a series of N-of-1 trials.
Topics: Blood Pressure; Humans; Hypertension; Male; Middle Aged; Nitrates; Sleep Apnea, Obstructive | 2016 |
[Obstructive sleep apnea contribution to oxidative stress in obesity].
Topics: Body Mass Index; Continuous Positive Airway Pressure; Humans; Male; Middle Aged; Nitrates; Nitrites; | 2008 |
Melatonin reduces microvascular damage and insulin resistance in hamsters due to chronic intermittent hypoxia.
Topics: Analysis of Variance; Animals; Blood Glucose; Cricetinae; Glucose Clamp Technique; Hemodynamics; Hyp | 2009 |
Effects of nasal continuous positive airway pressure treatment on oxidative stress and adiponectin levels in obese patients with obstructive sleep apnea.
Topics: Adiponectin; Case-Control Studies; Continuous Positive Airway Pressure; Humans; Insulin Resistance; | 2010 |
Serum nitrite and nitrate levels in children with obstructive sleep-disordered breathing.
Topics: Analysis of Variance; Blood Pressure; Chi-Square Distribution; Child; Child, Preschool; Female; Huma | 2010 |
Oxygen administration improves the serum level of nitric oxide metabolites in patients with obstructive sleep apnea syndrome.
Topics: Case-Control Studies; Female; Humans; Male; Middle Aged; Nitrates; Nitrites; Oxygen Inhalation Thera | 2003 |
Serum nitrite/nitrate levels in obstructive sleep apnea.
Topics: Case-Control Studies; Confounding Factors, Epidemiologic; Free Radicals; Hemodynamics; Humans; Neutr | 2001 |