Page last updated: 2024-10-19

nitrates and Shock

nitrates has been researched along with Shock in 29 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.

Research Excerpts

ExcerptRelevanceReference
" Here we investigated whether in vivo melatonin treatment inhibits cellular injury induced by peroxynitrite production and PARS activation in macrophages collected from rats subjected to zymosan-induced shock."7.70Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1998)
" Here we investigated whether in vivo N-acetylcysteine treatment inhibits cellular injury in macrophages collected from rats subjected to zymosan-induced shock."7.70Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1999)
" The current study was designed to investigate the protective effect of melatonin, a radical scavenger and antioxidant, on non-septic shock induced by zymosan in the rat."7.70Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. ( Caputi, AP; Cuzzocrea, S; El-Sokkary, GH; Hassanein, AF; Reiter, RJ; Tan, DX, 1999)
" Here we investigated whether in vivo melatonin treatment inhibits cellular injury induced by peroxynitrite production and PARS activation in macrophages collected from rats subjected to zymosan-induced shock."3.70Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1998)
" Here we investigated whether in vivo N-acetylcysteine treatment inhibits cellular injury in macrophages collected from rats subjected to zymosan-induced shock."3.70Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1999)
" The current study was designed to investigate the protective effect of melatonin, a radical scavenger and antioxidant, on non-septic shock induced by zymosan in the rat."3.70Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. ( Caputi, AP; Cuzzocrea, S; El-Sokkary, GH; Hassanein, AF; Reiter, RJ; Tan, DX, 1999)
"To analyze the mechanism of vasodilation and circulatory shock occurring in patients who are treated with isolated limb perfusion with melphalan and recombinant tumor necrosis factor (TNF)-alpha for locally advanced malignant tumors."3.69Role of nitric oxide in recombinant tumor necrosis factor-alpha-induced circulatory shock: a study in patients treated for cancer with isolated limb perfusion. ( Donse, IF; Girbes, AR; Hoekstra, HJ; Maring, JK; Moshage, H; Schraffordt Koops, H; van Ginkel, RJ; Zwaveling, JH, 1996)
"SAO shock was induced by clamping both the superior mesenteric artery and the celiac trunk, followed by release of the clamp."1.30IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock. ( Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Mazzon, E, 1999)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's18 (62.07)18.2507
2000's9 (31.03)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Impellizzeri, D1
Mazzon, E5
Di Paola, R1
Paterniti, I1
Bramanti, P1
Cuzzocrea, S11
Venkataraman, R1
Kellum, JA1
Song, M1
Fink, MP1
Kataoka, H1
Dünser, MW1
Werner, ER1
Wenzel, V1
Ulmer, H1
Friesenecker, BE1
Hasibeder, WR1
Mayr, AJ1
Chiao, CW1
Lee, SS1
Wu, CC1
Su, MJ1
Gamelli, RL1
George, M1
Sharp-Pucci, M1
Dries, DJ1
Radisavljevic, Z1
Wong, HR1
Carcillo, JA1
Burckart, G1
Kaplan, SS1
Szabó, C4
Zwaveling, JH1
Maring, JK1
Moshage, H1
van Ginkel, RJ1
Hoekstra, HJ1
Schraffordt Koops, H1
Donse, IF1
Girbes, AR1
Filippelli, A1
Zingarelli, B3
Falciani, M1
Caputi, AP11
Rossi, F1
Pajak, A1
Costantino, G5
Rubanyi, GM1
Fukuma, K1
Marubayashi, S1
Okada, K2
Yamada, K1
Kimura, A1
Dohi, K1
de Sarro, G2
Laurà, R1
Ciriaco, E1
de Sarro, A3
Ciliberto, G1
El-Sokkary, GH1
Reiter, RJ1
Hassanein, AF1
Tan, DX1
Squadrito, F1
Altavilla, D1
Squadrito, G1
Ferlito, M1
Deodato, B1
Arlotta, M1
Minutoli, L1
Campo, GM1
Bova, A1
Quartarone, C1
Urna, G1
Sardella, A1
Saitta, A1
Traber, DL1
Dugo, L1
Barbera, A1
Centorrino, T1
Ciccolo, A1
Fonti, MT1
Jagtap, P1
Soriano, FG1
Virág, L1
Liaudet, L1
Mabley, J1
Szabó, E1
Haskó, G1
Marton, A1
Lorigados, CB1
Gallyas, F1
Sümegi, B1
Hoyt, DG1
Baloglu, E1
VanDuzer, J1
Salzman, AL1
Southan, GJ1
von Segesser, LK1
Lehmann, K1
Turina, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double - Blind, Placebo - Controlled Trial to Investigate the Effect of Dapagliflozin on Ischemia Reperfusion Induced Endothelial Dysfunction of the Forearm Vasculature in Healthy Male Subjects[NCT05217654]Phase 132 participants (Anticipated)Interventional2022-02-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for nitrates and Shock

ArticleYear
The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.
    Shock (Augusta, Ga.), 1996, Volume: 6, Issue:2

    Topics: Animals; Humans; Hydroxyl Radical; Inflammation; Ischemia; Nitrates; Nitric Oxide; Nitric Oxide Synt

1996
Role of poly(ADP-ribose) synthetase activation in the suppression of cellular energetics in response to nitric oxide and peroxynitrite.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Animals; Diabetes Mellitus; DNA Damage; Energy Metabolism; Enzyme Activation; Humans; Hydroxyl Radic

1997
Nitric oxide and circulatory shock.
    Advances in experimental medicine and biology, 1998, Volume: 454

    Topics: Animals; Humans; Microcirculation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synth

1998
[Progress on physiopathological study of shock--Approach from the molecular biological point of view].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48 Suppl

    Topics: Adrenomedullin; Apoptosis; Gene Expression; Heat-Shock Response; Humans; Isoenzymes; Myocardial Depr

1999

Trials

1 trial available for nitrates and Shock

ArticleYear
Arginine vasopressin and serum nitrite/nitrate concentrations in advanced vasodilatory shock.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:7

    Topics: Aged; Arginine Vasopressin; Blood Pressure; Humans; Middle Aged; Nitrates; Nitrites; Prospective Stu

2004

Other Studies

24 other studies available for nitrates and Shock

ArticleYear
Effect of NADPH-oxidase inhibitors in the experimental model of zymosan-induced shock in mice.
    Free radical research, 2011, Volume: 45, Issue:7

    Topics: Acetophenones; Animals; Apoptosis; Cytokines; Enzyme Inhibitors; Male; Mice; Multiple Organ Failure;

2011
Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:6

    Topics: Animals; Cytokines; Disease Models, Animal; Isotonic Solutions; Lactic Acid; Lipopolysaccharides; Ma

2002
[Acute circulatory collapse in an elderly patient after administration of sublingual nitrate].
    Journal of cardiology, 2002, Volume: 40, Issue:5

    Topics: Administration, Sublingual; Aged; Aged, 80 and over; Female; Heart Valve Diseases; Humans; Hypovolem

2002
Thaliporphine increases survival rate and attenuates multiple organ injury in LPS-induced endotoxaemia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 371, Issue:1

    Topics: Animals; Aorta; Aporphines; Blood Glucose; Endotoxemia; Hemodynamics; In Vitro Techniques; Interleuk

2005
Burn-induced nitric oxide release in humans.
    The Journal of trauma, 1995, Volume: 39, Issue:5

    Topics: Anion Exchange Resins; Burns; Chromatography, High Pressure Liquid; Humans; Nitrates; Nitric Oxide;

1995
Nitric oxide production in critically ill patients.
    Archives of disease in childhood, 1996, Volume: 74, Issue:6

    Topics: Child; Critical Illness; Graft Rejection; Humans; Infections; Nitrates; Nitric Oxide; Nitrites; Orga

1996
Role of nitric oxide in recombinant tumor necrosis factor-alpha-induced circulatory shock: a study in patients treated for cancer with isolated limb perfusion.
    Critical care medicine, 1996, Volume: 24, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chemotherapy, Cancer, Regional Perfusion

1996
Role of nitric oxide in a nonseptic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:5

    Topics: Acute Disease; Animals; Ascitic Fluid; Blood Pressure; Cardiovascular Diseases; Enzyme Inhibitors; M

1997
[Myocardial infarction--risks and procedures. Longitudinal observation of a population of 280,000 women and men--Project POL-MONICA Krakow. I V: Prognosis of non-invasive treatment in myocardial infarction within 28 days since its onset].
    Przeglad lekarski, 1996, Volume: 53, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Confidence Inter

1996
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:5

    Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macro

1998
Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock.
    Life sciences, 1998, Volume: 63, Issue:9

    Topics: Analysis of Variance; Animals; Constriction; Enzyme Inhibitors; Ileum; Immunohistochemistry; Male; N

1998
Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in a non-septic shock model induced by zymosan in the rat.
    Journal of pineal research, 1998, Volume: 25, Issue:2

    Topics: Animals; Cell Respiration; Cells, Cultured; DNA Damage; Energy Metabolism; Enzyme Activation; Macrop

1998
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:2

    Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Respon

1999
Effect of lazaroid U-74389G and methylprednisolone on endotoxin-induced shock in mice.
    Surgery, 1999, Volume: 125, Issue:4

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases;

1999
Role of interleukin-6 in a non-septic shock model induced by zymosan.
    European cytokine network, 1999, Volume: 10, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Ascites; Ascitic Fluid; DNA Damage; Energy Metabolism; Injections,

1999
IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Celiac Artery; Constriction; Cytokines

1999
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan.
    Shock (Augusta, Ga.), 1999, Volume: 12, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Kidne

1999
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage;

1999
Protective effects of cyclosporin-A in splanchnic artery occlusion shock.
    British journal of pharmacology, 2000, Volume: 130, Issue:2

    Topics: Animals; Aorta; Arterial Occlusive Diseases; Blood Pressure; Cyclosporine; Enzyme Activation; Immuno

2000
Antiperoxynitrite strategies for the experimental therapy of shock.
    Critical care medicine, 2000, Volume: 28, Issue:6

    Topics: Animals; Nitrates; Oxidants; Shock

2000
Nitric oxide synthase and tissue injury.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Alprostadil; Animals; Arginine; Burns; Enzyme Inhibitors; Humans; Ischemia; Luminescent Measurements

2000
Inducible nitric oxide synthase knockout mice exhibit resistance to the multiple organ failure induced by zymosan.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:1

    Topics: Animals; Enzyme Inhibitors; Exudates and Transudates; Guanidines; Lipid Peroxidation; Liver; Lung; M

2001
Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents.
    Critical care medicine, 2002, Volume: 30, Issue:5

    Topics: Animals; Bleomycin; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Enzyme Activa

2002
Deleterious effects of shock in internal mammary artery anastomoses.
    The Annals of thoracic surgery, 1989, Volume: 47, Issue:4

    Topics: Animals; Coronary Circulation; Dogs; Epinephrine; Hemodynamics; Humans; Internal Mammary-Coronary Ar

1989