nitrates has been researched along with Shock, Septic in 119 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 7.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| "Magnolol is a compound extracted from the Chinese medicinal herb Magnolia officinalis." | 5.36 | Beneficial effects of magnolol in a rodent model of endotoxin shock. ( Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH, 2010) |
| "Septic shock is characterized by a decrease in systemic vascular resistance." | 5.31 | Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia. ( Chen, A; Chen, SJ; Chou, TC; Liao, MH; Wu, CC; Yen, MH, 2000) |
| "In endotoxic and hemorrhagic shock and splanchic ischemia-reperfusion, dihydrorhodamine oxidation rapidly increased, which was prevented by inhibition of endothelial nitric oxide (." | 5.29 | Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury. ( Ischiropoulos, H; Salzman, AL; Szabó, C, 1995) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 3.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| "Treatment with gentamicin stabilized cardiac index (BL, 5." | 2.71 | Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury. ( Enkhbaatar, P; Heggers, JP; Herndon, DN; Jodoin, JM; Maybauer, DM; Maybauer, MO; Morita, N; Traber, DL; Traber, LD; Westphal, M, 2005) |
| "Endotoxic shock was induced by lipopolysaccharide (LPS) in male Balb/c mice." | 1.39 | Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock. ( Amezcua-Guerra, LM; Argueta, I; Bojalil, R; Bolaños, L; Camacho-Villegas, TA; García-Ubbelohde, WJ; Licea-Navarro, AF; Márquez-Velasco, R; Mata-González, MT; Paniagua-Solís, JF; Sánchez-Castrejón, E; Sánchez-Muñoz, F; Yee, Y, 2013) |
| "Results Patients who developed septic shock (n = 35) had higher plasma NOx, total and free cortisol, and lower CBG concentrations than the nonseptic shock group (n = 27)." | 1.36 | Characteristics of plasma NOx levels in severe sepsis: high interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels. ( Chapman, MJ; Edwards, J; Ho, JT; Lam, S; Lewis, JG; Ludbrook, G; O'Connor, S; Torpy, DJ, 2010) |
| "Magnolol is a compound extracted from the Chinese medicinal herb Magnolia officinalis." | 1.36 | Beneficial effects of magnolol in a rodent model of endotoxin shock. ( Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH, 2010) |
| "mononuclears of patients with septic shock." | 1.33 | Differential inducible nitric oxide synthase activity in circulating neutrophils vs. mononuclears of septic shock patients. ( Cepinkas, G; Hersch, M; Izbicki, G; McCormack, D; Ostermann, M; Scott, JA; Sibbald, WJ, 2005) |
| "Treatment with ibuprofen, either before or after ETX, partly restored the elevated levels of nitrite/nitrate." | 1.33 | Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock. ( Akbulut, H; Ayar, A; Canbaz, M; Celik, I; Vural, P, 2005) |
| "Patients with septic shock have a shortage in the availability of arginine associated with a slower production." | 1.33 | In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis. ( Balasubramanyam, A; Bandi, VP; Gopal, J; Guntupalli, K; Jahoor, F; Villalpando, S, 2006) |
| "Recent findings in human septic shock suggest that glucocorticosteroids can limit and even reverse hemodynamic disturbances and dependence on catecholamines." | 1.32 | Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock. ( Bollaert, PE; Levy, B; Longrois, D; Mallié, JP; Mansart, A; Seguin, C, 2003) |
| "In this acute endotoxic shock model, CVVH with the polyacrylonitrile membrane improved cardiac performance when compared with the polysulphone membrane." | 1.32 | Comparison of polyacrylonitrile (AN69) and polysulphone membrane during hemofiltration in canine endotoxic shock. ( Pauwels, D; Rogiers, P; Vincent, JL; Zhang, H, 2003) |
| "The mechanism of gut injury in endotoxic shock seems unrelated to hypoxia and release of nitric oxide." | 1.32 | Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia. ( De Backer, D; Dimopoulos, G; Lobo, SM; Nagy, N; Preiser, JC; Sun, Q; Terzi, RG; Tu, Z; Vercruy, V; Vincent, JL; Vray, B, 2003) |
| "Sepsis was induced by cecal ligation and puncture (CLP) method." | 1.32 | Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis. ( Bhaduri, S; Maitra, SR; Ramamurthy, N; Sorsa, T; Tervahartiala, T; Valane, PD, 2003) |
| "Endotoxic shock was induced by administration of Escherichia coli endotoxin in rats." | 1.31 | Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents. ( Hake, PW; Malhotra, V; O'Connor, M; Sheehan, M; Wong, HR; Zingarelli, B, 2002) |
| "Gram-positive septic shock was induced by coadministration of LTA (3 mg/kg i." | 1.31 | Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of gram-positive shock. ( Cuzzocrea, S; Foster, SJ; Olbrich, A; Thiemermann, C; Zacharowski, K, 2000) |
| "Septic shock is characterized by a decrease in systemic vascular resistance." | 1.31 | Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia. ( Chen, A; Chen, SJ; Chou, TC; Liao, MH; Wu, CC; Yen, MH, 2000) |
| "Using a guinea pig model of endotoxic shock, we investigated the effect of genistein and tyrphostin AG 556 on the cardiac action potential." | 1.31 | Genistein and tyrphostin AG 556 block the action potential shortening in septic shock. ( Chiang, CE; Ding, PY; Luk, HN; Sheu, JR; Wang, TM, 2002) |
| "Sixteen patients admitted for septic shock." | 1.31 | Nitric oxide indices in human septic shock. ( Giercksky, KE; Kirkebøen, KA; Leone, A; Strand, OA, 2000) |
| "The incidence of sepsis and septic shock due to gram-positive organisms has increased dramatically over the last two decades." | 1.31 | A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the ra ( Foster, SJ; Hinds, CJ; Thiemermann, C; Wray, GM, 2001) |
| "In the seven patients with renal failure, both nitrate and tetrahydrobiopterin concentrations tended to be higher than in the 13 patients without renal failure." | 1.31 | Circulating tetrahydrobiopterin concentrations in patients with septic shock. ( Galley, HF; Grant, IS; Le Cras, AE; Webster, NR; Yassen, K, 2001) |
| " Our results indicated that selected in vivo dosage regimens of DETC (intraperitoneal: at -2, -1, 3, 6, and 10 h or at -2, -1, 3, 6, 9, 12, 15, and 18 h relative to lipopolysaccharide administration, 180 mg/kg, at t = 0) in endotoxic mice were effective in increasing survival time when compared with untreated animals and DETC pretreatment was more effective than methylprednisolone (p<." | 1.30 | Diethyldithiocarbamate prolongs survival of mice in a lipopolysaccharide-induced endotoxic shock model: evidence for multiple mechanisms. ( Fung, HL; Kishnani, NS; Tabrizi-Fard, MA, 1999) |
| "To determine in children with sepsis syndrome and septic shock the time course of nitric oxide metabolites: nitrate and nitrite (nitrogen oxides)." | 1.30 | Activation of the L-arginine nitric oxide pathway in severe sepsis. ( Duke, T; South, M; Stewart, A, 1997) |
| "The best predictive value for septic shock was found to be the measurements of NO2-/NO3- and procalcitonin concentrations." | 1.30 | Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia. ( Assicot, M; Baumgartner, JD; Bohuon, C; Chioléro, R; Corradin, SB; de Werra, I; Gallati, H; Glauser, MP; Heumann, D; Jaccard, C; Yersin, B, 1997) |
| "Endotoxin shock was induced in rats by bacterial lipopolysaccharide." | 1.30 | Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. ( Cuzzocrea, S; O'Connor, M; Salzman, AL; Szabó, C; Zingarelli, B, 1997) |
| "Twenty-two children diagnosed with septic shock and ten age-matched healthy control patients." | 1.30 | Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock. ( Brilli, R; Denenberg, A; Krafte-Jacobs, B; Moore, L; Salzman, AL; Szabó, C, 1997) |
| "In brains from victims of Parkinson's disease, a nitrosyl species, identified as nitrosyl hemoglobin, has been observed in substantia nigra." | 1.30 | Applications of electron paramagnetic resonance spectroscopy to study interactions of iron proteins in cells with nitric oxide. ( Ananda Inalsingh, V; Cammack, R; Hughes, MN; Shergill, JK, 1998) |
| "In endotoxic and hemorrhagic shock and splanchic ischemia-reperfusion, dihydrorhodamine oxidation rapidly increased, which was prevented by inhibition of endothelial nitric oxide (." | 1.29 | Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury. ( Ischiropoulos, H; Salzman, AL; Szabó, C, 1995) |
| " This investigation demonstrates that treatment with NO-inhalation, in order to prevent the dramatic increase in MPAP, PVR and the alterations in peripheral blood gases combined with systemic L-NMMAto improve systemic MABP and thus organ perfusion, may be a new therapeutic regimen in the treatment of septic shock." | 1.29 | Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock. ( Henning, R; Klemm, P; Martorana, PA; Thiemermann, C; Winklmaier, G, 1995) |
| "Thirteen patients with septic shock were studied within 6 h after the development of hypotension." | 1.29 | Relationship between circulating levels of calcitonin gene-related peptide, nitric oxide metabolites and hemodynamic changes in human septic shock. ( Arnalich, F; Hernanz, A; Jiménez, M; López, J; Montiel, C; Tato, E; Vázquez, JJ, 1996) |
| "IL-1ra increases survival during endotoxic shock and attenuates production of TNF but not NO." | 1.29 | Maintenance of dynamic microvascular function and structure in a rat model of endotoxic shock by blockade of the interleukin-1 receptor. ( Baker, CH; Franz, MS; Norman, JG; Sutton, ET, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 63 (52.94) | 18.2507 |
| 2000's | 47 (39.50) | 29.6817 |
| 2010's | 8 (6.72) | 24.3611 |
| 2020's | 1 (0.84) | 2.80 |
| Authors | Studies |
|---|---|
| Dhanani, LY | 1 |
| Totton, RR | 1 |
| Jara-Quijada, E | 1 |
| Pérez-Won, M | 1 |
| Tabilo-Munizaga, G | 1 |
| Lemus-Mondaca, R | 1 |
| González-Cavieres, L | 1 |
| Palma-Acevedo, A | 1 |
| Herrera-Lavados, C | 1 |
| Milovanovic, S | 1 |
| Grzegorczyk, A | 1 |
| Świątek, Ł | 1 |
| Grzęda, A | 1 |
| Dębczak, A | 1 |
| Tyskiewicz, K | 1 |
| Konkol, M | 1 |
| Li, Y | 2 |
| Chang, P | 1 |
| Sankaran, S | 1 |
| Jang, H | 1 |
| Nie, Y | 1 |
| Zeng, A | 1 |
| Hussain, S | 1 |
| Wu, JY | 1 |
| Chen, X | 2 |
| Shi, L | 2 |
| Senapati, A | 1 |
| Chetri, BK | 1 |
| Mitra, S | 1 |
| Shelke, RG | 1 |
| Rangan, L | 1 |
| Chauhan, AS | 1 |
| Tiwari, M | 1 |
| Indoliya, Y | 1 |
| Mishra, SK | 1 |
| Lavania, UC | 1 |
| Chauhan, PS | 1 |
| Chakrabarty, D | 1 |
| Tripathi, RD | 1 |
| Akaputra, R | 1 |
| Hatta, M | 1 |
| Massi, MN | 1 |
| Djaharuddin, I | 1 |
| Bukhari, A | 1 |
| Aminuddin, A | 1 |
| Santoso, A | 1 |
| Natzir, R | 1 |
| Bahar, B | 1 |
| Fachri, M | 1 |
| Farsida, F | 1 |
| Fathimah, A | 1 |
| Ubaidah, FM | 1 |
| Sridiana, E | 1 |
| Dwiyanti, R | 1 |
| Syukri, A | 1 |
| Junita, AR | 1 |
| Febrianti, A | 1 |
| Primaguna, MR | 1 |
| Azhar, A | 1 |
| Rajaure, YS | 1 |
| Thapa, B | 1 |
| Budhathoki, L | 1 |
| Rana, SR | 1 |
| Khadka, M | 1 |
| Batchu, UR | 1 |
| Surapaneni, JR | 1 |
| Cheemalamarri, C | 1 |
| Mandava, K | 1 |
| Puvvada, N | 1 |
| Shetty, PR | 1 |
| Mv, S | 1 |
| Ranjbarian, P | 1 |
| Goudarzi, F | 1 |
| Akya, A | 1 |
| Heidarinia, H | 1 |
| Farasat, A | 1 |
| Rostamian, M | 1 |
| Suri, K | 1 |
| Rajput, N | 1 |
| Sharma, P | 1 |
| Omble, AD | 1 |
| Kulkarni, K | 1 |
| Gahlay, GK | 1 |
| Fernandez Garcia, E | 1 |
| Paudel, U | 1 |
| Noji, MC | 1 |
| Bowman, CE | 1 |
| Rustgi, AK | 1 |
| Pitarresi, JR | 1 |
| Wellen, KE | 1 |
| Arany, Z | 1 |
| Weissenrieder, JS | 1 |
| Foskett, JK | 1 |
| Lee, MS | 1 |
| Han, HJ | 1 |
| Choi, TI | 1 |
| Lee, KH | 1 |
| Baasankhuu, A | 1 |
| Kim, HT | 1 |
| Kim, CH | 1 |
| Redd, PS | 1 |
| Payero, L | 1 |
| Gilbert, DM | 1 |
| Page, CA | 1 |
| King, R | 1 |
| McAssey, EV | 1 |
| Bodie, D | 1 |
| Diaz, S | 1 |
| Hancock, CN | 1 |
| Lee, HS | 1 |
| Jung, S | 1 |
| Lee, SW | 1 |
| Kim, YT | 1 |
| Lee, J | 1 |
| Ren, T | 1 |
| Yu, Z | 1 |
| Yu, H | 1 |
| Deng, K | 1 |
| Wang, Z | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Wang, L | 2 |
| Xu, Y | 1 |
| Lascano, J | 1 |
| Riley, L | 1 |
| Khodayari, N | 1 |
| Brantly, M | 1 |
| Gupta, R | 1 |
| Pradhan, J | 1 |
| Haldar, A | 1 |
| Murapaka, C | 1 |
| Chandra Mondal, P | 1 |
| Gao, R | 1 |
| Dai, TY | 1 |
| Meng, Z | 1 |
| Sun, XF | 1 |
| Liu, DX | 1 |
| Shi, MM | 1 |
| Li, HR | 1 |
| Kang, X | 1 |
| Bi, B | 1 |
| Zhang, YT | 1 |
| Xu, TW | 1 |
| Yan, JM | 1 |
| Jiang, Q | 1 |
| Helmchen, G | 1 |
| Guo, H | 1 |
| Xiang, W | 1 |
| Fang, Y | 1 |
| Li, J | 4 |
| Lin, Y | 1 |
| An, X | 1 |
| Jiang, D | 1 |
| Cao, Q | 1 |
| Xu, F | 1 |
| Shiigi, H | 1 |
| Wang, W | 1 |
| Chen, Z | 1 |
| Akosman, I | 1 |
| Kumar, N | 1 |
| Mortenson, R | 1 |
| Lans, A | 1 |
| De La Garza Ramos, R | 1 |
| Eleswarapu, A | 1 |
| Yassari, R | 1 |
| Fourman, MS | 1 |
| Jana, S | 1 |
| Evans, EGB | 1 |
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| Zhang, S | 2 |
| Zhang, H | 3 |
| Rajca, A | 1 |
| Gordon, SE | 1 |
| Zagotta, WN | 1 |
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| Miller, S | 1 |
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| Muhimpundu, S | 1 |
| Maxwell, CA | 1 |
| Liu, Z | 1 |
| Shen, F | 1 |
| Tong, Q | 1 |
| Tang, M | 1 |
| Peng, M | 1 |
| Jiao, Z | 1 |
| Jiang, Y | 1 |
| Ao, L | 1 |
| Fu, W | 1 |
| Lv, X | 1 |
| Jiang, G | 1 |
| Hou, L | 1 |
| Tu, WC | 1 |
| McManamen, AM | 1 |
| Su, X | 1 |
| Jeacopello, I | 1 |
| Takezawa, MG | 1 |
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| Shinkawa, VAM | 1 |
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| Kretzschmar, R | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Natural History of Procalcitonin in Hemorrhagic Stroke[NCT01498705] | 0 participants (Actual) | Observational | 2011-12-31 | Withdrawn (stopped due to Anticipated grant was withdrawn and additional funding was unable to be obtained) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for nitrates and Shock, Septic
| Article | Year |
|---|---|
The role of mitochondrial nitric oxide synthase in inflammation and septic shock.
Topics: Animals; Humans; Inflammation; Lipopolysaccharides; Mitochondria; Nitrates; Nitric Oxide; Nitric Oxi | 2002 |
[Septic shock and NO].
Topics: Animals; Biomarkers; Guanidines; Guanylate Cyclase; Hemodynamics; Humans; Methylene Blue; Nitrates; | 2004 |
[Significance of endogenous nitric oxide production for the effect of nitrates and in septic shock].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Endothelium, Vascular; Humans; Nitrates; Nitric Oxide | 1993 |
Role of nitric oxide in endotoxic shock. An overview of recent advances.
Topics: Anti-Inflammatory Agents; Disease Models, Animal; Enzyme Inhibitors; Gene Deletion; Humans; Nitrates | 1998 |
Nitric oxide and circulatory shock.
Topics: Animals; Humans; Microcirculation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synth | 1998 |
4 trials available for nitrates and Shock, Septic
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com | 2023 |
Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury.
Topics: Animals; Arteries; Blood Pressure; Female; Gentamicins; Hemodynamics; Lung; Nitrates; Nitric Oxide; | 2005 |
Effect of L-NAME, an inhibitor of nitric oxide synthesis, on plasma levels of IL-6, IL-8, TNF alpha and nitrite/nitrate in human septic shock.
Topics: APACHE; Drug Monitoring; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukin-6; Interl | 1998 |
Circulating endothelin and nitrate-nitrite relate to hemodynamic and metabolic variables in human septic shock.
Topics: Adult; Aged; Aged, 80 and over; Blood Vessels; Cardiotonic Agents; Creatinine; Cytokines; Dopamine; | 1999 |
110 other studies available for nitrates and Shock, Septic
| Article | Year |
|---|---|
Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock.
Topics: Animals; Biomarkers; Disease Models, Animal; Humans; Inflammation; Interleukin-10; Interleukin-6; Li | 2013 |
Alpha-lipoic acid prevents endotoxic shock and multiple organ dysfunction syndrome induced by endotoxemia in rats.
Topics: Animals; Antioxidants; Antithrombins; Aorta; Caspase 3; Disulfides; Endotoxemia; Enzyme Activation; | 2015 |
A neutrophil elastase inhibitor, sivelestat, reduces lung injury following endotoxin-induced shock in rats by inhibiting HMGB1.
Topics: Animals; Glycine; HMGB1 Protein; Interleukin-6; Leukocyte Elastase; Lipopolysaccharides; Lung; Lung | 2008 |
Effects of dobutamine on gut mucosal nitric oxide production during endotoxic shock in rabbits.
Topics: Animals; Coronary Circulation; Dobutamine; Heart Rate; Intestinal Mucosa; Lactic Acid; Lipopolysacch | 2009 |
Hemodynamic, metabolic, and organ function effects of pure oxygen ventilation during established fecal peritonitis-induced septic shock.
Topics: Animals; Apoptosis; Biomarkers; Comet Assay; Dinoprost; DNA Damage; Nitrates; Nitrites; Oxidative St | 2009 |
Characteristics of plasma NOx levels in severe sepsis: high interindividual variability and correlation with illness severity, but lack of correlation with cortisol levels.
Topics: Analysis of Variance; Dobutamine; Epinephrine; Female; Humans; Hydrocortisone; Intensive Care Units; | 2010 |
Beneficial effects of magnolol in a rodent model of endotoxin shock.
Topics: Animals; Antithrombin III; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Gene Expressi | 2010 |
The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock.
Topics: Acute Lung Injury; Animals; Catalysis; Disease Models, Animal; Female; Lung; Malondialdehyde; Nitrat | 2011 |
Protective effects of tryptophan on neuro-inflammation in rats after administering lipopolysaccharide.
Topics: Animals; Antioxidants; Cerebral Cortex; Drug Interactions; Female; Free Radical Scavengers; Hippocam | 2011 |
Effects of combined levosimendan and vasopressin on pulmonary function in porcine septic shock.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Drug Therapy, Combination; Female; Hemodynamics; HMG- | 2012 |
Role of active nitrogen molecules in progression of septic shock.
Topics: Adult; APACHE; Creatinine; Critical Care; Critical Illness; Disease Progression; Enzyme-Linked Immun | 2012 |
Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock.
Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cyclic AMP; Dexamethasone; Dose-Response Relatio | 2003 |
Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice.
Topics: Animals; B-Lymphocytes; Disease Susceptibility; HMGB1 Protein; I-kappa B Proteins; Interleukin-1; In | 2003 |
Genistein and tyrphostin AG 556 block the action potential shortening in septic shock.
Topics: Action Potentials; Animals; Cyclic GMP; Female; Genistein; Guinea Pigs; Heart; Male; Myocardium; Nit | 2002 |
Comparison of polyacrylonitrile (AN69) and polysulphone membrane during hemofiltration in canine endotoxic shock.
Topics: Acrylic Resins; Animals; Bicarbonates; Biocompatible Materials; Dogs; Endotoxins; Escherichia coli; | 2003 |
Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia.
Topics: Animals; Blood Pressure; Carbon Dioxide; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Lipopolysa | 2003 |
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Extracellular Matrix; | 2003 |
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Func | 2003 |
Propofol ameliorates liver dysfunction and inhibits aortic superoxide level in conscious rats with endotoxic shock.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Endotoxins; Escherichia coli; Heart Rate; Kidn | 2003 |
Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats.
Topics: Animals; Blood Pressure; Cholesterol; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydro | 2004 |
Low-dose dexamethasone ameliorates circulatory failure and renal dysfunction in conscious rats with endotoxemia.
Topics: Animals; Arteries; Blood Pressure; Blotting, Western; Calcium; Dexamethasone; Endotoxemia; Escherich | 2004 |
Calpain inhibitors improve myocardial dysfunction and inflammation induced by endotoxin in rats.
Topics: Animals; Cardiomyopathies; Endotoxins; Glycoproteins; Heart; In Vitro Techniques; Inflammation; Inje | 2004 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.
Topics: Animals; Aorta; Blood Pressure; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Chromones; Cy | 2005 |
Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.
Topics: Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug; | 2005 |
Hyperbaric oxygen protects against lipopolysaccharide-stimulated oxidative stress and mortality in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanid | 2005 |
Differential inducible nitric oxide synthase activity in circulating neutrophils vs. mononuclears of septic shock patients.
Topics: Hospitals, University; Humans; Intensive Care Units; Leukocytes, Mononuclear; Neutrophils; Nitrates; | 2005 |
Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats.
Topics: Animals; Antioxidants; Aorta; Bilirubin; Blood Pressure; Blotting, Western; Cell Line; Down-Regulati | 2005 |
Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypotension; Ibuprofen; | 2005 |
Cytokine profile of human septic shock serum inducing cardiomyocyte contractile dysfunction.
Topics: Adolescent; Animals; Cytokines; Humans; Myocardial Contraction; Myocytes, Cardiac; Nitrates; Nitrite | 2007 |
In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis.
Topics: Adult; Aged; Arginine; Case-Control Studies; Critical Illness; Female; Glomerular Filtration Rate; H | 2006 |
Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep.
Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Lung; Microcirculation; Multipl | 2006 |
Flurbiprofen and its nitric oxide-releasing derivative protect against septic shock in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cecum; Disease Models, Animal; Flu | 2006 |
Assessment of inflammatory mediators in patients with generalized peritonitis.
Topics: Adult; Aged; Aged, 80 and over; Cytokines; Endotoxins; Female; Group IV Phospholipases A2; Humans; I | 1999 |
Ceftazidime improves hemodynamics and oxygenation in ovine smoke inhalation injury and septic shock.
Topics: Animals; Anti-Bacterial Agents; Blood Pressure; Ceftazidime; Disease Models, Animal; Female; Heart R | 2007 |
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
Topics: Animals; Base Sequence; Disease Models, Animal; Drug Resistance; Immunoblotting; Interferon-gamma; L | 1995 |
Inhibition of nitric oxide synthase in experimental gram-negative sepsis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Escherichia coli; Escherichia coli Infections; Liver; | 1994 |
Is endotoxin-induced hypotension related to nitric oxide formation?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Hypotension; Nitrates | 1994 |
Role of vascular nitric oxide synthase in endotoxin shock of Propionibacterium acnes-sensitized rats.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Dexamethasone; Enz | 1994 |
Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock.
Topics: Administration, Inhalation; Amino Acid Oxidoreductases; Animals; Arginine; Blood Gas Analysis; Esche | 1995 |
Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury.
Topics: Animals; Male; Nitrates; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury; Rhodamines; Sh | 1995 |
Maintenance of dynamic microvascular function and structure in a rat model of endotoxic shock by blockade of the interleukin-1 receptor.
Topics: Acetylcholine; Animals; Aorta; Arterioles; Blood Pressure; Endothelium, Vascular; Endotoxins; Hemody | 1995 |
Detection of nitric oxide production in mice by spin-trapping electron paramagnetic resonance spectroscopy.
Topics: Animals; Arginine; Chelating Agents; Electron Spin Resonance Spectroscopy; Female; Ferrous Compounds | 1995 |
[Cytokines and nitric oxide in streptococcal toxic shock syndrome].
Topics: Adult; Cytokines; Endotoxins; Female; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Male; Mid | 1995 |
L-arginine: nitric oxide pathway in endotoxemia and human septic shock.
Topics: Arginine; Cardiac Output; Creatinine; Endotoxins; Female; Humans; Kidney; Male; Nitrates; Nitric Oxi | 1995 |
Sources of nitrates and nitrites in neonates with sepsis.
Topics: Humans; Infant, Newborn; Nitrates; Nitric Oxide; Nitrites; Shock, Septic | 1994 |
Evidence of increased nitric oxide production in patients with the sepsis syndrome.
Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Female; Humans; Hypotension; Male; Middle Aged; | 1993 |
Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite.
Topics: Animals; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mitochondria; Nitrates; Nitric Oxide; Ox | 1996 |
Beneficial effects of L-canavanine, a selective inhibitor of inducible nitric oxide synthase, during rodent endotoxaemia.
Topics: Acidosis, Lactic; Animals; Arginine; Blood Pressure; Canavanine; Heart Rate; Lipopolysaccharides; Ma | 1996 |
Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli.
Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Free Radical Scaveng | 1996 |
Effect of multiple cytokines plus bacterial endotoxin on glucose and nitric oxide production by cultured hepatocytes.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Drug Interactions; Enzyme Inhibitors; Glucose; Lipopo | 1996 |
Nitrite/nitrate (NOX) and type II phospholipase A2, leukotriene B4, and platelet-activating factor levels in patients with septic shock.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Group II Phospholipases A2; Humans; Leu | 1996 |
Melatonin as a therapeutic agent in experimental endotoxic shock.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Escherichia coli; Female; L | 1996 |
Relationship between circulating levels of calcitonin gene-related peptide, nitric oxide metabolites and hemodynamic changes in human septic shock.
Topics: Adult; Calcitonin Gene-Related Peptide; Hemodynamics; Humans; Middle Aged; Nitrates; Nitric Oxide; N | 1996 |
Pteridine and nitrite/nitrate formation in experimental septic and traumatic shock.
Topics: Animals; Arteries; Cardiac Output; Creatinine; Disease Models, Animal; Escherichia coli Infections; | 1996 |
Intraperitoneal injection of tetracyclines protects mice from lethal endotoxemia downregulating inducible nitric oxide synthase in various organs and cytokine and nitrate secretion in blood.
Topics: Animals; Anti-Bacterial Agents; Cytokines; Down-Regulation; Doxycycline; Endotoxemia; Enzyme Inducti | 1997 |
Endothelial structural integrity is maintained during endotoxic shock in an interleukin-1 type 1 receptor knockout mouse.
Topics: Animals; Endothelium, Vascular; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitra | 1997 |
The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock.
Topics: Animals; Cells, Cultured; Lipopolysaccharides; Male; Metalloporphyrins; Mice; Mitochondria; Muscle, | 1997 |
Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Free Radicals; Humans; Kidney Failure, | 1997 |
Nitric oxide (NO) production correlates with renal insufficiency and multiple organ dysfunction syndrome in severe sepsis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Male; Middle Aged; Multiple Organ Failur | 1996 |
Activation of the L-arginine nitric oxide pathway in severe sepsis.
Topics: Adolescent; Arginine; Biomarkers; Child; Child, Preschool; Female; Humans; Infant; Male; Multiple Or | 1997 |
Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; Cohort Stud | 1997 |
Measurements of total plasma nitrite and nitrate in pediatric patients with the systemic inflammatory response syndrome.
Topics: Child, Preschool; Cohort Studies; Humans; Infant; Infant, Newborn; Nitrates; Nitrites; Predictive Va | 1997 |
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
Topics: Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Humans; Lipopolysaccharides; Mic | 1997 |
Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock.
Topics: Adolescent; Biomarkers; Blood Gas Analysis; Case-Control Studies; Child; Child, Preschool; Female; H | 1997 |
Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of endotoxic shock.
Topics: Adrenalectomy; Animals; Biopterins; Dexamethasone; Disease Models, Animal; Enzyme Induction; Escheri | 1997 |
Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock.
Topics: Animals; Canavanine; Enzyme Inhibitors; Female; L-Lactate Dehydrogenase; Lipase; Lipopolysaccharides | 1998 |
In vivo quantification of endotoxin-induced nitric oxide production in pigs from Na15NO3-infusion.
Topics: Animals; Blood Pressure; Carcinogens; Endotoxins; Enzyme Inhibitors; Infusions, Intravenous; Nitrate | 1997 |
Plasma nitrite and nitrate concentrations and multiple organ failure in pediatric sepsis.
Topics: Adolescent; Bacteremia; Child; Child, Preschool; Follow-Up Studies; Humans; Infant; Infant, Newborn; | 1998 |
Selective iNOS inhibition is superior to norepinephrine in the treatment of rat endotoxic shock.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluati | 1998 |
Doxycycline reduces mortality to lethal endotoxemia by reducing nitric oxide synthesis via an interleukin-10-independent mechanism.
Topics: Animals; Anti-Bacterial Agents; Doxycycline; Endotoxemia; Female; Interleukin-10; Lipopolysaccharide | 1998 |
Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure.
Topics: Animals; Aorta, Thoracic; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Endothelium, Vascu | 1998 |
Endotoxin-induced skeletal muscle contractile dysfunction: contribution of nitric oxide synthases.
Topics: Animals; Disease Models, Animal; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Skeletal; Ni | 1998 |
Selective inhibition of the activity of inducible nitric oxide synthase prevents the circulatory failure, but not the organ injury/dysfunction, caused by endotoxin.
Topics: Amidines; Animals; Benzylamines; Enzyme Inhibitors; Escherichia coli; Hemodynamics; Kidney; Lipopoly | 1998 |
Effect of septic shock on nitrate, free amino acids, and urea in murine plasma and urine.
Topics: Amino Acids; Animals; Blood Proteins; Creatinine; Escherichia coli; Female; Lipopolysaccharides; Mic | 1998 |
Pulmonary hypertension and reduced cardiac output during inhibition of nitric oxide synthesis in human septic shock.
Topics: Aged; Cardiac Output; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension, Pulmonary; Male; NG-Nit | 1998 |
Nitric oxide and the haemodynamic profile of endotoxin shock in the conscious mouse.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Enzyme Inhibitors; Female; Hemodynamics; Interle | 1998 |
Protective effect of ciliary neurotrophic factor (CNTF) in a model of endotoxic shock: action mechanisms and role of CNTF receptor alpha.
Topics: Adrenalectomy; Animals; Ciliary Neurotrophic Factor; Disease Models, Animal; Humans; Lipopolysacchar | 1998 |
Peroxynitrite production by human neutrophils, monocytes and lymphocytes challenged with lipopolysaccharide.
Topics: Adult; Enzyme Inhibitors; Female; Guanidines; Humans; Lipopolysaccharides; Lymphocytes; Male; Middle | 1998 |
Plasma levels of type II phospholipase A2 and nitrite/nitrate in patients with burns.
Topics: Adult; Aged; Biomarkers; Burns; Enzyme-Linked Immunosorbent Assay; Female; Group II Phospholipases A | 1998 |
Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production.
Topics: Aging; Animals; Cyclic GMP; Gene Expression Regulation, Developmental; Gene Expression Regulation, E | 1998 |
Endothelin-1 and blood pressure after inhibition of nitric oxide synthesis in human septic shock.
Topics: Blood Pressure; Endothelin-1; Female; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitr | 1999 |
Applications of electron paramagnetic resonance spectroscopy to study interactions of iron proteins in cells with nitric oxide.
Topics: Animals; Bacteria; Cysteine; Electron Spin Resonance Spectroscopy; Food Preservation; Hemeproteins; | 1998 |
Beneficial effects of L-canavanine, a selective inhibitor of inducible nitric oxide synthase, on lactate metabolism and muscle high energy phosphates during endotoxic shock in rats.
Topics: Adenosine Triphosphate; Animals; Canavanine; Energy Metabolism; Enzyme Inhibitors; Hydrogen-Ion Conc | 1999 |
Oral spermine administration inhibits nitric oxide-mediated intestinal damage and levels of systemic inflammatory mediators in a mouse endotoxin model.
Topics: Administration, Oral; Animals; Disease Models, Animal; Escherichia coli; Female; Immunohistochemistr | 1999 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Mod | 1999 |
Diethyldithiocarbamate prolongs survival of mice in a lipopolysaccharide-induced endotoxic shock model: evidence for multiple mechanisms.
Topics: Animals; Chelating Agents; Collagenases; Ditiocarb; Dose-Response Relationship, Drug; Female; Gelati | 1999 |
Diethylmaleate and buthionine sulfoximine, glutathione-depleting agents, differentially inhibit expression of inducible nitric oxide synthase in endotoxemic mice.
Topics: Animals; Buthionine Sulfoximine; Gene Expression Regulation, Enzymologic; Glutathione; Interleukin-1 | 1999 |
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Rad | 1999 |
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock.
Topics: Animals; Aorta; Cell Respiration; Cells, Cultured; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Te | 1999 |
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Topics: Animals; Antioxidants; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema | 2000 |
Resistance to endotoxin shock in transgenic mice overexpressing endothelial nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Cyclic GMP; Edema; Female; Granulocytes; Hypotension; Immunity, Inna | 2000 |
Beneficial effects of sanguisorbae radix in renal dysfunction caused by endotoxin in vivo.
Topics: Animals; Blood Urea Nitrogen; Creatine; Drugs, Chinese Herbal; Endotoxins; Male; Nitrates; Nitric Ox | 1999 |
Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of gram-positive shock.
Topics: Animals; Blood Pressure; Cyclic N-Oxides; Free Radical Scavengers; Kidney; Lipopolysaccharides; Live | 2000 |
Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Drug Interactions | 2000 |
Antiplatelet activity of Staphylococcus aureus lipoteichoic acid is mediated through a cyclic AMP pathway.
Topics: Alprostadil; Blood Platelets; Blood Proteins; Calcium Signaling; Collagen; Cyclic AMP; Cyclic GMP; C | 2000 |
Nitrite/nitrate (NOx) levels and hemodynamics during septic shock.
Topics: Adult; Aged; Endotoxins; Female; Hemodynamics; Humans; Interleukin-8; Male; Middle Aged; Nitrates; N | 2000 |
Nitric oxide indices in human septic shock.
Topics: Adolescent; Adult; Humans; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Severity of Illnes | 2000 |
Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice.
Topics: Animals; Aorta, Thoracic; Bacterial Proteins; Blood Pressure; Body Temperature; Cells, Cultured; Esc | 2001 |
A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the ra
Topics: Animals; Bacillus subtilis; Blood Pressure; Cell Wall; Dose-Response Relationship, Drug; Drug Synerg | 2001 |
Indices of nitric oxide synthesis and outcome in critically ill patients.
Topics: Aged; APACHE; Biomarkers; Critical Care; Cyclic GMP; Female; Humans; Logistic Models; Male; Middle A | 2001 |
Circulating tetrahydrobiopterin concentrations in patients with septic shock.
Topics: APACHE; Biomarkers; Biopterins; Chromatography, High Pressure Liquid; Humans; Nitrates; Renal Insuff | 2001 |
Recombinant tissue factor pathway inhibitor prevents lipopolysaccharide-induced systemic hypotension in rats by inhibiting excessive production of nitric oxide.
Topics: Animals; Dansyl Compounds; Enzyme Induction; Enzyme Inhibitors; Factor VIIa; Factor Xa Inhibitors; G | 2001 |
Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats.
Topics: Animals; Antithrombin III; Disease Models, Animal; Endotoxins; Enzyme Induction; Epoprostenol; Human | 2002 |
A synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock.
Topics: Animals; Aorta; Cell Line; Disease Models, Animal; DNA; Drug Interactions; Fibrinolytic Agents; Gene | 2002 |
Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Apoptosis; Disease Models, Animal; DNA; DNA | 2002 |
Is nitrate anion a mediator of organ system injury in rats injected with lipopolysaccharide?
Topics: Animals; Lipopolysaccharides; Multiple Organ Failure; Nitrates; Nitric Oxide; Rats; Shock, Septic | 2002 |
The hemodynamic effects of diaspirin cross-linked hemoglobin in dopamine-resistant endotoxic shock in swine.
Topics: Animals; Aspirin; Blood Pressure; Blood Substitutes; Cardiotonic Agents; Dopamine; Drug Resistance; | 2002 |
Protective effects of isohelenin, an inhibitor of nuclear factor kappaB, in endotoxic shock in rats.
Topics: Acetylcholine; Animals; Blotting, Western; Electrophoresis; Endotoxins; Hemodynamics; Lipopolysaccha | 2002 |
Inducible nitric oxide synthase is not required in the development of endotoxin tolerance in mice.
Topics: Animals; Drug Tolerance; Endotoxins; Female; I-kappa B Proteins; Interleukin-10; Lung; Male; Mice; M | 2002 |
The role of nitric oxide in endotoxic shock: effects of NG-monomethyl-L-arginine.
Topics: Alanine Transaminase; Animals; Arginine; Blood Pressure; Dexamethasone; Lipopolysaccharides; Male; N | 1992 |