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nitrates and Neurodegenerative Diseases

nitrates has been researched along with Neurodegenerative Diseases in 25 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"Nitric oxide metabolites, nitrates, and nitrites (NNx), were measured in the cerebrospinal fluid (CSF) of children with PEHO syndrome or PEHO-like syndrome, and in controls with other neurologic diseases."3.70Markedly elevated nitrate/nitrite levels in the cerebrospinal fluid of children with progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO syndrome). ( Riikonen, R; Vanhatalo, S, 2000)
"Hypercapnia is regularly observed in chronic lung disease, such as bronchopulmonary dysplasia in preterm infants."1.36Sustained hypercapnia induces cerebral microvascular degeneration in the immature brain through induction of nitrative stress. ( Balazy, M; Chemtob, S; Hamel, D; Hardy, P; Honoré, JC; Hou, X; Jankov, RP; Kooli, A; Mancini, JA; Picard, E; Rivera, JC; Tremblay, S; Varma, DR, 2010)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (28.00)18.2507
2000's15 (60.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Zhang, ZH1
Hu, J1
Chen, Q4
Chen, J1
Hu, X1
Koh, K1
Chen, H1
Xu, XH1
Troška, P1
Chudoba, R1
Danč, L1
Bodor, R1
Horčičiak, M1
Tesařová, E1
Masár, M1
Honoré, JC1
Kooli, A1
Hou, X1
Hamel, D1
Rivera, JC1
Picard, E1
Hardy, P1
Tremblay, S1
Varma, DR1
Jankov, RP1
Mancini, JA1
Balazy, M1
Chemtob, S1
Papay, R1
Zuscik, MJ1
Ross, SA1
Yun, J1
McCune, DF1
Gonzalez-Cabrera, P1
Gaivin, R1
Drazba, J1
Perez, DM1
Ischiropoulos, H5
Horiguchi, T1
Uryu, K1
Giasson, BI4
LightFoot, R1
Bellmann, C1
Richter-Landsberg, C1
Lee, VM4
Trojanowski, JQ3
Hyun, DH1
Gray, DA1
Halliwell, B1
Jenner, P1
Bernardo, A1
Gasparini, L1
Ongini, E1
Minghetti, L1
Joshi, G1
Perluigi, M1
Sultana, R1
Agrippino, R1
Calabrese, V1
Butterfield, DA2
Sacksteder, CA1
Qian, WJ1
Knyushko, TV1
Wang, H1
Chin, MH1
Lacan, G1
Melega, WP1
Camp, DG1
Smith, RD1
Smith, DJ1
Squier, TC1
Bigelow, DJ1
Mason, RP1
Cockcroft, JR1
Gurwitz, D1
Kloog, Y1
Carrizo, PH1
Dubin, M1
Stoppani, AO1
Dawson, VL1
Dawson, TM1
Heales, SJ1
Bolaños, JP1
Stewart, VC1
Brookes, PS1
Land, JM1
Clark, JB1
Oh-hashi, K1
Maruyama, W1
Yi, H1
Takahashi, T1
Naoi, M1
Isobe, K1
Sayre, LM1
Perry, G1
Smith, MA1
Torreilles, F1
Salman-Tabcheh, S1
Guérin, M1
Torreilles, J1
Souza, JM1
Vanhatalo, S1
Riikonen, R1
Duda, JE1
Gur, TL1
Hurtig, HI1
Stern, MB1
Gollomp, SM1
Wakita, T1
Shintani, F1
Yagi, G1
Asai, M1
Nozawa, S1
Kanski, J1
Drake, J1
Aksenova, M1
Engman, L1
Knapp, LT1
Kanterewicz, BI1
Hayes, EL1
Klann, E1
Paxinou, E1
Weisse, M1
Norris, EH1
Rueter, SM1

Reviews

5 reviews available for nitrates and Neurodegenerative Diseases

ArticleYear
Oxidative modifications of alpha-synuclein.
    Annals of the New York Academy of Sciences, 2003, Volume: 991

    Topics: alpha-Synuclein; Animals; Humans; Nerve Tissue Proteins; Neurodegenerative Diseases; Nitrates; Oxida

2003
Targeting nitric oxide with drug therapy.
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:12 Suppl 4

    Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzopyrans

2006
Nitric oxide in neurodegeneration.
    Progress in brain research, 1998, Volume: 118

    Topics: AIDS Dementia Complex; Animals; Cerebrovascular Disorders; Humans; Neurodegenerative Diseases; Neuro

1998
Nitric oxide, mitochondria and neurological disease.
    Biochimica et biophysica acta, 1999, Feb-09, Volume: 1410, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Astrocytes; Cell Death; Electron Transport; Glutamic Acid; Humans; Mi

1999
Neurodegenerative disorders: the role of peroxynitrite.
    Brain research. Brain research reviews, 1999, Volume: 30, Issue:2

    Topics: Alzheimer Disease; Animals; Central Nervous System; Humans; Inflammation; Motor Neuron Disease; Mult

1999

Other Studies

20 other studies available for nitrates and Neurodegenerative Diseases

ArticleYear
The magnetic-nanoparticle-assisted sensitive detection of nitrated α-syn in blood based on a sensitizing electrochemical layer.
    Nanoscale, 2021, May-06, Volume: 13, Issue:17

    Topics: alpha-Synuclein; Biosensing Techniques; Electrochemical Techniques; Gold; Humans; Immunoassay; Limit

2021
Determination of nitrite and nitrate in cerebrospinal fluid by microchip electrophoresis with microsolid phase extraction pre-treatment.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jul-01, Volume: 930

    Topics: Adolescent; Adult; Biomarkers; Electrophoresis, Microchip; Female; Humans; Limit of Detection; Linea

2013
Sustained hypercapnia induces cerebral microvascular degeneration in the immature brain through induction of nitrative stress.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Hypercapnia; Neurodegenerative Diseases; Nitrates; Nitric Oxide Sy

2010
Mice expressing the alpha(1B)-adrenergic receptor induces a synucleinopathy with excessive tyrosine nitration but decreased phosphorylation.
    Journal of neurochemistry, 2002, Volume: 83, Issue:3

    Topics: Adrenergic alpha-Antagonists; alpha-Synuclein; Animals; Body Weight; Brain; Cerebellum; Disease Mode

2002
Nitration of tau protein is linked to neurodegeneration in tauopathies.
    The American journal of pathology, 2003, Volume: 163, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Corte

2003
Interference with ubiquitination causes oxidative damage and increased protein nitration: implications for neurodegenerative diseases.
    Journal of neurochemistry, 2004, Volume: 90, Issue:2

    Topics: Aldehydes; Antioxidants; Cell Division; Cell Line; Cell Survival; Clone Cells; Cysteine Endopeptidas

2004
Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases.
    Neurobiology of disease, 2006, Volume: 22, Issue:1

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinopros

2006
In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-re
    Neurochemistry international, 2006, Volume: 48, Issue:4

    Topics: Aldehydes; Amidines; Animals; Caffeic Acids; Ferrous Compounds; Gerbillinae; Heme Oxygenase (Decycli

2006
Endogenously nitrated proteins in mouse brain: links to neurodegenerative disease.
    Biochemistry, 2006, Jul-04, Volume: 45, Issue:26

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Sequence; Animals; Brain; Capillary Action;

2006
Peroxynitrite generation might explain elevated glutamate and aspartate levels in multiple sclerosis cerebrospinal fluid.
    European journal of clinical investigation, 1998, Volume: 28, Issue:9

    Topics: Animals; Aspartic Acid; Glutamic Acid; Humans; Models, Biological; Multiple Sclerosis; Neurodegenera

1998
[Physiopathologic effects of nitric oxide and their relationship with oxidative stress].
    Medicina, 1998, Volume: 58, Issue:4

    Topics: Antioxidants; Humans; Liver Transplantation; Neoplasms; Neurodegenerative Diseases; Nitrates; Nitric

1998
Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells.
    Biochemical and biophysical research communications, 1999, Sep-24, Volume: 263, Issue:2

    Topics: Antioxidants; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors

1999
In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
    Methods in enzymology, 1999, Volume: 309

    Topics: Aldehydes; Alzheimer Disease; Analysis of Variance; Biomarkers; DNA Damage; Glycation End Products,

1999
Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies.
    The Journal of biological chemistry, 2000, Jun-16, Volume: 275, Issue:24

    Topics: alpha-Synuclein; Electrophoresis, Polyacrylamide Gel; Humans; Nerve Tissue Proteins; Neurodegenerati

2000
Markedly elevated nitrate/nitrite levels in the cerebrospinal fluid of children with progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO syndrome).
    Epilepsia, 2000, Volume: 41, Issue:6

    Topics: Adolescent; Age Factors; Atrophy; Brain; Child; Child, Preschool; Humans; Infant; Neurodegenerative

2000
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies.
    The American journal of pathology, 2000, Volume: 157, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Antibodies; Blotting, Western; Brain Diseases; Fema

2000
Combination of inflammatory cytokines increases nitrite and nitrate levels in the paraventricular nucleus of conscious rats.
    Brain research, 2001, Jun-29, Volume: 905, Issue:1-2

    Topics: Animals; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Encephalitis; Immunohistoch

2001
Antioxidant activity of the organotellurium compound 3-[4-(N,N-dimethylamino)benzenetellurenyl]propanesulfonic acid against oxidative stress in synaptosomal membrane systems and neuronal cultures.
    Brain research, 2001, Aug-17, Volume: 911, Issue:1

    Topics: Alkanesulfonic Acids; Animals; Antioxidants; Cell Death; Cell Membrane; Cell Survival; Cells, Cultur

2001
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C.
    Biochemical and biophysical research communications, 2001, Aug-31, Volume: 286, Issue:4

    Topics: Animals; Brain; Cysteine; Isoenzymes; Male; Neurodegenerative Diseases; Nitrates; Nitric Oxide Donor

2001
Induction of alpha-synuclein aggregation by intracellular nitrative insult.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Oct-15, Volume: 21, Issue:20

    Topics: alpha-Synuclein; Ammonium Chloride; beta-Synuclein; Cell Line; Cysteine Endopeptidases; Enzyme Inhib

2001