nitrates has been researched along with Nerve Degeneration in 27 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by autonomic failure, parkinsonism, cerebellar ataxia, and oligodendrocytic accumulation of alpha-synuclein (alphasyn)." | 7.75 | Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. ( Adame, A; Inglis, C; Lee, PH; Mante, M; Masliah, E; Rockenstein, E; Stefanova, N; Ubhi, K; Wenning, GK, 2009) |
| "Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by autonomic failure, parkinsonism, cerebellar ataxia, and oligodendrocytic accumulation of alpha-synuclein (alphasyn)." | 3.75 | Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. ( Adame, A; Inglis, C; Lee, PH; Mante, M; Masliah, E; Rockenstein, E; Stefanova, N; Ubhi, K; Wenning, GK, 2009) |
| "To investigate whether nitric oxide (NO) plays a role in degenerative neurologic disease (DND), we measured nitrite, nitrate and cyclic GMP in cerebrospinal fluid (CSF) samples from patients with Parkinson's disease (PD), spinocerebellar ataxia (SCA) and amyotrophic lateral sclerosis (ALS)." | 3.69 | Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic diseases. ( Ikeda, M; Miyatake, T; Murota, S; Sato, I; Yuasa, T, 1995) |
| "The developing cortical neurons have been well documented to be extremely vulnerable to the toxic effect of methylmercury (MeHg)." | 1.31 | Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity. ( Arimura, K; Eto, K; Fukuyama, N; Miyamoto, K; Moriguchi, S; Murao, K; Nakanishi, H; Osame, M; Wakamiya, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 19 (70.37) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armagan, G | 1 |
| Kanit, L | 1 |
| Terek, CM | 1 |
| Sozmen, EY | 1 |
| Yalcin, A | 1 |
| Ubhi, K | 1 |
| Lee, PH | 1 |
| Adame, A | 1 |
| Inglis, C | 1 |
| Mante, M | 1 |
| Rockenstein, E | 1 |
| Stefanova, N | 1 |
| Wenning, GK | 1 |
| Masliah, E | 1 |
| Goryacheva, AV | 1 |
| Kruglov, SV | 1 |
| Pshennikova, MG | 1 |
| Smirin, BV | 1 |
| Malyshev, IY | 1 |
| Barskov, IV | 1 |
| Viktorov, IV | 1 |
| Downey, HF | 1 |
| Manukhina, EB | 1 |
| Zhao, Q | 1 |
| Zhang, C | 1 |
| Wang, X | 1 |
| Chen, L | 1 |
| Ji, H | 1 |
| Zhang, Y | 1 |
| Zizza, M | 1 |
| Giusi, G | 1 |
| Crudo, M | 1 |
| Canonaco, M | 1 |
| Facciolo, RM | 1 |
| Horiguchi, T | 1 |
| Uryu, K | 1 |
| Giasson, BI | 2 |
| Ischiropoulos, H | 2 |
| LightFoot, R | 1 |
| Bellmann, C | 1 |
| Richter-Landsberg, C | 1 |
| Lee, VM | 2 |
| Trojanowski, JQ | 2 |
| Fernández-Vizarra, P | 1 |
| Fernández, AP | 1 |
| Castro-Blanco, S | 1 |
| Encinas, JM | 1 |
| Serrano, J | 1 |
| Bentura, ML | 1 |
| Muñoz, P | 1 |
| Martínez-Murillo, R | 1 |
| Rodrigo, J | 1 |
| Guo, Z | 1 |
| Iyun, T | 1 |
| Fu, W | 1 |
| Zhang, P | 1 |
| Mattson, MP | 1 |
| Mishizen-Eberz, AJ | 1 |
| Norris, EH | 1 |
| Hodara, R | 1 |
| Lynch, DR | 1 |
| Sultana, R | 1 |
| Poon, HF | 1 |
| Cai, J | 1 |
| Pierce, WM | 1 |
| Merchant, M | 1 |
| Klein, JB | 1 |
| Markesbery, WR | 1 |
| Butterfield, DA | 1 |
| Al-Majed, AA | 1 |
| Sayed-Ahmed, MM | 1 |
| Al-Omar, FA | 1 |
| Al-Yahya, AA | 1 |
| Aleisa, AM | 1 |
| Al-Shabanah, OA | 1 |
| Deng, Y | 1 |
| Thompson, BM | 1 |
| Gao, X | 1 |
| Hall, ED | 1 |
| Bayir, H | 1 |
| Kagan, VE | 1 |
| Clark, RS | 1 |
| Janesko-Feldman, K | 1 |
| Rafikov, R | 1 |
| Huang, Z | 1 |
| Zhang, X | 1 |
| Vagni, V | 1 |
| Billiar, TR | 1 |
| Kochanek, PM | 1 |
| Hwang, WS | 1 |
| Chen, SH | 1 |
| Lin, CH | 1 |
| Chang, HK | 1 |
| Chen, WC | 1 |
| Lin, MT | 1 |
| Beckman, JS | 1 |
| Chen, J | 1 |
| Crow, JP | 1 |
| Ye, YZ | 1 |
| Kuiper, MA | 1 |
| Visser, JJ | 1 |
| Bergmans, PL | 1 |
| Scheltens, P | 1 |
| Wolters, EC | 1 |
| Ikeda, M | 1 |
| Sato, I | 1 |
| Yuasa, T | 1 |
| Miyatake, T | 1 |
| Murota, S | 1 |
| Barker, JE | 1 |
| Bolaños, JP | 1 |
| Land, JM | 1 |
| Clark, JB | 1 |
| Heales, SJ | 1 |
| Kaal, EC | 1 |
| Kil, AC | 1 |
| Sodaar, P | 1 |
| Joosten, EA | 1 |
| Bär, PR | 1 |
| Taskiran, D | 1 |
| Sagduyu, A | 1 |
| Yüceyar, N | 1 |
| Kutay, FZ | 1 |
| Pögün, S | 1 |
| Liu, T | 1 |
| Knight, KR | 1 |
| Tracey, DJ | 1 |
| Fassbender, K | 1 |
| Fatar, M | 1 |
| Ragoschke, A | 1 |
| Picard, M | 1 |
| Bertsch, T | 1 |
| Kuehl, S | 1 |
| Hennerici, M | 1 |
| Golden, WC | 1 |
| Brambrink, AM | 1 |
| Traystman, RJ | 1 |
| Martin, LJ | 1 |
| Miyamoto, K | 1 |
| Nakanishi, H | 1 |
| Moriguchi, S | 1 |
| Fukuyama, N | 1 |
| Eto, K | 1 |
| Wakamiya, J | 1 |
| Murao, K | 1 |
| Arimura, K | 1 |
| Osame, M | 1 |
| Manabe, Y | 1 |
| Wang, JM | 1 |
| Murakami, T | 1 |
| Warita, H | 1 |
| Hayashi, T | 1 |
| Shoji, M | 1 |
| Abe, K | 1 |
| Palomba, L | 1 |
| Sestili, P | 1 |
| Cantoni, O | 1 |
| Stoffel, M | 1 |
| Rinecker, M | 1 |
| Graf, R | 1 |
| Baethmann, A | 1 |
| Plesnila, N | 1 |
1 review available for nitrates and Nerve Degeneration
| Article | Year |
|---|---|
Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain Ischemia; Cattle; Glutamic Acid; Humans; Macrophages; | 1994 |
26 other studies available for nitrates and Nerve Degeneration
| Article | Year |
|---|---|
The levels of glutathione and nitrite-nitrate and the expression of Bcl-2 mRNA in ovariectomized rats treated by raloxifene against kainic acid.
Topics: Animals; Apoptosis; Disease Models, Animal; Female; Glutathione; Kainic Acid; Nerve Degeneration; Ne | 2009 |
Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy.
Topics: alpha-Synuclein; Animals; Brain; Convulsants; Disease Models, Animal; Mice; Mice, Transgenic; Mitoch | 2009 |
Adaptation to intermittent hypoxia restricts nitric oxide overproduction and prevents beta-amyloid toxicity in rat brain.
Topics: Adaptation, Physiological; Amyloid beta-Peptides; Animals; Brain; Hypoxia; Male; Nerve Degeneration; | 2010 |
(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death.
Topics: Animals; Benzofurans; Cell Death; Cinnamates; Disease Models, Animal; Hypoxia-Ischemia, Brain; Male; | 2012 |
Lead-induced neurodegenerative events and abnormal behaviors occur via ORXRergic/GABA(A)Rergic mechanisms in a marine teleost.
Topics: Animals; Behavior, Animal; Bicuculline; Brain; Feeding Behavior; GABA-A Receptor Antagonists; Gene E | 2013 |
Nitration of tau protein is linked to neurodegeneration in tauopathies.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Corte | 2003 |
Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cell Death; Humans; Immunohistochemistry; Middle Aged; N | 2004 |
Bone marrow transplantation reveals roles for brain macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death.
Topics: Animals; Bone Marrow Transplantation; Cell Death; Cell Differentiation; Genetic Predisposition to Di | 2004 |
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein.
Topics: alpha-Synuclein; Calpain; Chymotrypsin; Humans; Hydrolysis; Microscopy, Immunoelectron; Nerve Degene | 2005 |
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; ATP Synthetase Complexes; Carbonic Anhydrase II; Female; | 2006 |
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Disease Models, Animal; Energy Metaboli | 2006 |
Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.
Topics: Aldehydes; Animals; Brain; Brain Injuries; Calcium; Calpain; Cerebral Cortex; Cytoskeleton; Lipid Pe | 2007 |
Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.
Topics: Adolescent; Adult; Aged; Animals; Brain; Brain Injuries; Chemotaxis, Leukocyte; Encephalitis; Enzyme | 2007 |
Human umbilical cord blood-derived CD34+ cells can be used as a prophylactic agent for experimental heatstroke.
Topics: Animals; Antigens, CD34; Basal Ganglia; Cerebrovascular Disorders; Cord Blood Stem Cell Transplantat | 2008 |
Decreased cerebrospinal fluid nitrate levels in Parkinson's disease, Alzheimer's disease and multiple system atrophy patients.
Topics: Aged; Alzheimer Disease; Atrophy; Dementia; Female; Humans; Male; Middle Aged; Nerve Degeneration; N | 1994 |
Nitrite, nitrate and cGMP in the cerebrospinal fluid in degenerative neurologic diseases.
Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Cyclic GMP; Female; Humans; Male; Middle Aged; Nerv | 1995 |
Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration.
Topics: Animals; Astrocytes; Glutathione; Mitochondria; Nerve Degeneration; Neurons; Nitrates; Rats; Rats, W | 1996 |
Cobalt prevents nitric oxide-induced apoptotic motoneuron death in vitro.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Cells, Cultured; Cobalt; Cyclic GMP; Electrophy | 1999 |
Increased cerebrospinal fluid and serum nitrite and nitrate levels in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Female; Glutamates; Humans; Male; Middle Aged; Nerve Degeneration; Ni | 2000 |
Hyperalgesia due to nerve injury-role of peroxynitrite.
Topics: Animals; Hyperalgesia; Hyperthermia, Induced; Immunohistochemistry; Male; Nerve Compression Syndrome | 2000 |
Subacute but not acute generation of nitric oxide in focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Corpus Striatum; Enzyme Inhibitors; Guanidines; Microdialysis; Nerve Degene | 2000 |
Failure to sustain recovery of Na,K-ATPase function is a possible mechanism for striatal neurodegeneration in hypoxic-ischemic newborn piglets.
Topics: Animals; Animals, Newborn; Cell Death; Cerebral Palsy; Enzyme Activation; Hypoxia-Ischemia, Brain; N | 2001 |
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian P | 2001 |
Expressions of nitrotyrosine and TUNEL immunoreactivities in cultured rat spinal cord neurons after exposure to glutamate, nitric oxide, or peroxynitrite.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Central Nervous System Diseases; Enzyme Inhibitor | 2001 |
tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cell Membrane; Cell Membrane Permeability; Dose-Respons | 2001 |
Nitric oxide in the penumbra of a focal cortical necrosis in rats.
Topics: Animals; Brain Injuries; Cerebral Cortex; Cold Temperature; Extracellular Space; Male; Microdialysis | 2002 |