nitrates has been researched along with Muscle Relaxation in 71 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 7.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "Glyceryl trinitrate, isosorbide dinitrate, and isosorbide-5-mononitrate are organic nitrate esters commonly used in the treatment of angina pectoris, myocardial infarction, and congestive heart failure." | 4.79 | Mechanisms of action of nitrates. ( Ahlner, J; Torfgård, KE, 1994) |
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 3.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| " The increased activities of AS and AL suggest the increased and effective recycling of citrulline to arginine in excitotoxicity, making NO production more effective and contributing to its toxic effects." | 1.35 | Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain. ( Chandran, G; Sirajudeen, KN; Swamy, M, 2009) |
| "Medications that may increase gastroesophageal reflux could be risk factors for esophageal adenocarcinoma; however, epidemiologic studies present conflicting results." | 1.33 | Barrett's esophagus and medications that relax the lower esophageal sphincter. ( Buffler, PA; Corley, DA; Habel, LA; Levin, TR, 2006) |
| "Proteinuria was within normal limits in all groups studied but L-arg caused a significant decrease in this parameter in both the RA8 and RA12 groups." | 1.31 | L-Arginine effects on blood pressure and renal function of intrauterine restricted rats. ( Alves, GM; Barão, MA; Brandizzi, LI; Franco Md, Mdo C; Laurindo, FR; Lucas, SR; Nascimento Gomes, G; Nigro, D; Odo, LN; Zaladek Gil, F, 2002) |
| " The increased responsiveness of diabetic vessels to exogenous peroxynitrite seems to be related to depressed basal NO bioavailability and may be considered as a compensatory way against activated contractile mechanisms of diabetic vascular smooth muscle." | 1.31 | Effects of peroxynitrite on the reactivity of diabetic rat aorta. ( Cakici, I; Karasu , C; Zobali, F, 2001) |
| "Luminal thrombus induces arterial dysfunction acutely without causing endothelial cell loss." | 1.31 | Luminal thrombus disrupts nitric oxide-dependent endothelial physiology. ( Chiou, A; Clouse, WD; Davis, MR; DeCaprio, JD; Hagino, RT; Kashyap, VS; Kerby, JD; Ortegon, DP, 2002) |
| "Experiments were designed to investigate the effects of chronic administration of an NO donor, (+/-)-(E)-ethyl-2-[(E)-ethylhydroxyimino]-5-nitro-3-hexeneamide (FK409), on the impairment of the acetylcholine-induced endothelium-dependent relaxations of the aorta, perfused mesenteric arterial bed and perfused kidney that seen in streptozotocin-induced diabetic rats." | 1.30 | Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat. ( Hayashi, T; Kamata, K, 1999) |
| " Pyo (10 microM) surmountably inhibited aortic responses to GTN, isosorbide dinitrate, SIN-1, and SNAP with a characteristic rightward shift of the dose-response curve; the apparent EC50 of these drugs for relaxation of phenylephrine-contracted aorta was increased 18-, 4-, 13-, and 15-fold, respectively." | 1.29 | Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from nitric oxide formation. ( Bozinovski, J; Brien, JF; Marks, GS; Nakatsu, K, 1994) |
| " The rates of relaxation were then used to construct a pharmacodynamic model that described the time course of relaxation for these compounds." | 1.28 | Pharmacodynamic modeling of the in vitro vasodilating effects of organic mononitrates. ( Fung, HL; Tzeng, TB, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (11.27) | 18.7374 |
| 1990's | 38 (53.52) | 18.2507 |
| 2000's | 22 (30.99) | 29.6817 |
| 2010's | 3 (4.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fok, H | 1 |
| Guilcher, A | 1 |
| Li, Y | 1 |
| Brett, S | 1 |
| Shah, A | 1 |
| Clapp, B | 1 |
| Chowienczyk, P | 1 |
| Rocha, BS | 1 |
| Gago, B | 1 |
| Barbosa, RM | 1 |
| Cavaleiro, C | 1 |
| Laranjinha, J | 1 |
| Koyuncu, A | 1 |
| Bagcivan, I | 1 |
| Sarac, B | 1 |
| Aydin, C | 1 |
| Yildirim, S | 1 |
| Sarioglu, Y | 1 |
| Swamy, M | 1 |
| Sirajudeen, KN | 1 |
| Chandran, G | 1 |
| Jones, AW | 1 |
| Durante, W | 1 |
| Korthuis, RJ | 1 |
| Reynolds, JN | 1 |
| Bennett, BM | 2 |
| Boegman, RJ | 1 |
| Jhamandas, K | 1 |
| Ratz, JD | 1 |
| Zavorin, SI | 1 |
| Scutaru, D | 1 |
| Dumitrascu, A | 1 |
| Thatcher, GR | 1 |
| Alves, GM | 1 |
| Barão, MA | 1 |
| Odo, LN | 1 |
| Nascimento Gomes, G | 1 |
| Franco Md, Mdo C | 1 |
| Nigro, D | 1 |
| Lucas, SR | 1 |
| Laurindo, FR | 1 |
| Brandizzi, LI | 1 |
| Zaladek Gil, F | 1 |
| Taniguchi, J | 1 |
| Honda, H | 1 |
| Shibusawa, Y | 1 |
| Iwata, T | 1 |
| Notoya, Y | 1 |
| Corley, DA | 1 |
| Levin, TR | 1 |
| Habel, LA | 1 |
| Buffler, PA | 1 |
| Ushiyama, M | 1 |
| Kuramochi, T | 1 |
| Katayama, S | 1 |
| Valero, M | 1 |
| Pereboom, D | 1 |
| Garay, RP | 1 |
| Alda, JO | 1 |
| Shah, DI | 1 |
| Singh, M | 1 |
| L'hirondel, M | 1 |
| Soubeyrand, E | 1 |
| L'hirondel, JL | 1 |
| Rousselot, P | 1 |
| Letellier, P | 1 |
| Compère, JF | 1 |
| Bénateau, H | 1 |
| Matsuzaki, G | 1 |
| Ishizaka, N | 1 |
| Furuta, K | 1 |
| Hongo, M | 1 |
| Saito, K | 1 |
| Sakurai, R | 1 |
| Koike, K | 1 |
| Nagai, R | 2 |
| Sakanashi, M | 1 |
| Rokutanda, M | 1 |
| Takeo, S | 1 |
| Higuchi, M | 1 |
| Zelis, R | 1 |
| Darius, H | 1 |
| Weiss, P | 1 |
| Schrör, K | 1 |
| Kojda, G | 1 |
| Beck, JK | 1 |
| Meyer, W | 1 |
| Noack, E | 1 |
| Bozinovski, J | 1 |
| Brien, JF | 1 |
| Marks, GS | 1 |
| Nakatsu, K | 1 |
| Torfgård, KE | 1 |
| Ahlner, J | 1 |
| Arner, M | 1 |
| Uski, T | 1 |
| Högestätt, ED | 1 |
| Kasai, H | 1 |
| Fukata, Y | 1 |
| Harada, K | 1 |
| Fukushima, H | 1 |
| Ogawa, N | 1 |
| Wu, M | 1 |
| Pritchard, KA | 1 |
| Kaminski, PM | 1 |
| Fayngersh, RP | 1 |
| Hintze, TH | 1 |
| Wolin, MS | 1 |
| Miyata, N | 1 |
| Yamaura, H | 1 |
| Tanaka, M | 1 |
| Takahashi, K | 1 |
| Tsuchida, K | 1 |
| Otomo, S | 1 |
| Jin, JG | 1 |
| Murthy, KS | 1 |
| Grider, JR | 1 |
| Makhlouf, GM | 1 |
| Matsumoto, T | 1 |
| Okamura, T | 1 |
| Kinoshita, M | 1 |
| Toda, N | 1 |
| Mülsch, A | 1 |
| Bara, A | 1 |
| Mordvintcev, P | 1 |
| Vanin, A | 1 |
| Busse, R | 1 |
| Moro, MA | 1 |
| Darley-Usmar, VM | 1 |
| Lizasoain, I | 1 |
| Su, Y | 1 |
| Knowles, RG | 1 |
| Radomski, MW | 1 |
| Moncada, S | 1 |
| Iqbal, N | 1 |
| Knaus, EE | 1 |
| Ghaleh, B | 1 |
| Dubois-Randé, JL | 1 |
| Hittinger, L | 1 |
| Berdeaux, A | 1 |
| Giudicelli, JF | 1 |
| Desta, B | 1 |
| Nakashima, M | 1 |
| Vanhoutte, PM | 1 |
| Boulanger, CM | 1 |
| Donà, G | 1 |
| Giuliani, P | 1 |
| Cremonesi, P | 1 |
| Passaro, A | 1 |
| Stella, P | 1 |
| Tursi, F | 1 |
| Mizrahi, J | 1 |
| Lefer, DJ | 1 |
| Scalia, R | 1 |
| Campbell, B | 1 |
| Nossuli, T | 1 |
| Hayward, R | 1 |
| Salamon, M | 1 |
| Grayson, J | 1 |
| Lefer, AM | 1 |
| Dowell, FJ | 1 |
| Martin, W | 1 |
| Saito, Y | 1 |
| Yamagishi, T | 1 |
| Nakamura, T | 1 |
| Ohyama, Y | 1 |
| Aizawa, H | 1 |
| Suga, T | 1 |
| Matsumura, Y | 1 |
| Masuda, H | 1 |
| Kurabayashi, M | 1 |
| Kuro-o, M | 1 |
| Nabeshima, Y | 1 |
| Paris, D | 1 |
| Parker, TA | 1 |
| Town, T | 1 |
| Suo, Z | 1 |
| Fang, C | 1 |
| Humphrey, J | 1 |
| Crawford, F | 1 |
| Mullan, M | 1 |
| Herrmann, BW | 1 |
| Cullen, JJ | 1 |
| Ledlow, A | 1 |
| Murray, JA | 2 |
| Conklin, JL | 2 |
| Kamata, K | 1 |
| Hayashi, T | 2 |
| Murphy, ME | 1 |
| Kurjak, M | 1 |
| Koppitz, P | 1 |
| Schusdziarra, V | 1 |
| Allescher, HD | 1 |
| Goto, H | 1 |
| Shimada, Y | 1 |
| Tanigawa, K | 1 |
| Sekiya, N | 1 |
| Shintani, T | 1 |
| Terasawa, K | 1 |
| Murohara, T | 1 |
| Kugiyama, K | 1 |
| Ota, Y | 1 |
| Doi, H | 1 |
| Ogata, N | 1 |
| Ohgushi, M | 1 |
| Yasue, H | 1 |
| Manukhina, EB | 1 |
| Smirin, BV | 1 |
| Lyamina, NP | 1 |
| Senchikhin, VN | 1 |
| Vanin, AF | 1 |
| Jayachandran, M | 1 |
| Sumi, D | 1 |
| Thakur, NK | 1 |
| Esaki, T | 1 |
| Muto, E | 1 |
| Kano, H | 1 |
| Asai, Y | 1 |
| Iguchi, A | 1 |
| White, R | 1 |
| Crow, J | 1 |
| Spear, N | 1 |
| Thomas, S | 1 |
| Patel, R | 1 |
| Green, I | 1 |
| Beckman, J | 1 |
| Darley-Usmar, V | 1 |
| Seshita, H | 1 |
| Yoshida, M | 1 |
| Takahashi, W | 1 |
| Inadome, A | 1 |
| Yono, M | 1 |
| Miyamoto, Y | 1 |
| Murakami, S | 1 |
| Ueda, S | 1 |
| Hoşgör-Başgut, B | 1 |
| Başgut, E | 1 |
| Soyak, G | 1 |
| Tunçtan, B | 1 |
| Cakici, I | 2 |
| Kanzik, I | 1 |
| Uc, A | 1 |
| Kooy, N | 1 |
| Oğülener, N | 1 |
| Ergün, Y | 1 |
| Döndaş, N | 1 |
| Dikmen, A | 1 |
| Zobali, F | 1 |
| Karasu , C | 1 |
| de la Puerta, R | 1 |
| Martínez Domínguez, ME | 1 |
| Ruíz-Gutíerrez, V | 1 |
| Flavill, JA | 1 |
| Hoult, JR | 1 |
| Dick, JM | 1 |
| Van Molle, W | 1 |
| Libert, C | 1 |
| Lefebvre, RA | 1 |
| Hanspal, IS | 1 |
| Magid, KS | 1 |
| Webb, DJ | 1 |
| Megson, IL | 1 |
| Davis, MR | 1 |
| Ortegon, DP | 1 |
| Clouse, WD | 1 |
| Kerby, JD | 1 |
| DeCaprio, JD | 1 |
| Chiou, A | 1 |
| Hagino, RT | 1 |
| Kashyap, VS | 1 |
| Borovikov, IuS | 1 |
| Kirillina, VP | 1 |
| Chernogriadskaia, NA | 1 |
| Tzeng, TB | 1 |
| Fung, HL | 3 |
| Yeates, RA | 1 |
| Schmid, M | 1 |
| McDonald, BJ | 1 |
| Nigam, R | 1 |
| Long, PG | 1 |
| Simon, WC | 1 |
| Bogers, JJ | 1 |
| Pelckmans, PA | 1 |
| Boeckxstaens, GE | 1 |
| De Man, JG | 1 |
| Herman, AG | 1 |
| Van Maercke, YM | 1 |
| Hobbs, AJ | 1 |
| Tucker, JF | 1 |
| Gibson, A | 1 |
| Greenberg, SS | 1 |
| Cantor, E | 1 |
| Ho, E | 1 |
| Walega, M | 1 |
| Kowaluk, EA | 2 |
| Henry, PJ | 2 |
| Horowitz, JD | 2 |
| Louis, WJ | 2 |
| Vaughan, P | 1 |
| Fasehun, OA | 1 |
| Gross, SS | 2 |
| Rubin, LE | 1 |
| Jaffe, EA | 1 |
| Griffith, OW | 1 |
| Levi, R | 2 |
| Hata, F | 1 |
| Ishii, T | 1 |
| Kanada, A | 1 |
| Yamano, N | 1 |
| Kataoka, T | 1 |
| Takeuchi, T | 1 |
| Yagasaki, O | 1 |
| Allen, SL | 1 |
| Foster, RW | 1 |
| Morgan, GP | 1 |
| Small, RC | 1 |
| Stuehr, DJ | 1 |
| Sakuma, I | 1 |
| Nathan, CF | 1 |
| Snowdowne, KW | 1 |
3 reviews available for nitrates and Muscle Relaxation
| Article | Year |
|---|---|
[Salivary nitrates. New perspectives concerning the physiological function of saliva].
Topics: Animals; Cardiovascular Diseases; Diarrhea; Gastric Mucosa; Humans; Mouth; Muscle Relaxation; Muscle | 2007 |
Mechanisms of vasodilation.
Topics: Arachidonic Acids; Blood Circulation; Calcium; Eicosanoic Acids; Endothelium; Humans; Muscle Contrac | 1983 |
Mechanisms of action of nitrates.
Topics: Angina Pectoris; Blood Platelets; Cyclic GMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme Syst | 1994 |
1 trial available for nitrates and Muscle Relaxation
| Article | Year |
|---|---|
Augmentation pressure is influenced by ventricular contractility/relaxation dynamics: novel mechanism of reduction of pulse pressure by nitrates.
Topics: Adult; Aged; Arterial Pressure; Blood Pressure; Cardiac Catheterization; Dose-Response Relationship, | 2014 |
67 other studies available for nitrates and Muscle Relaxation
| Article | Year |
|---|---|
Ethyl nitrite is produced in the human stomach from dietary nitrate and ethanol, releasing nitric oxide at physiological pH: potential impact on gastric motility.
Topics: Adult; Animals; Diet; Ethanol; Gastric Emptying; Gastric Mucosa; Humans; Lactuca; Muscle Relaxation; | 2015 |
Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter.
Topics: Anal Canal; Animals; Isosorbide Dinitrate; Models, Animal; Muscle Relaxation; Muscle, Smooth; Nitrat | 2008 |
Nitric oxide (NO), citrulline-NO cycle enzymes, glutamine synthetase, and oxidative status in kainic acid-mediated excitotoxicity in rat brain.
Topics: Animals; Aspartic Acid; Brain; Citrulline; Endothelium, Vascular; Glutamate-Ammonia Ligase; Kainic A | 2009 |
Heme oxygenase-1 deficiency leads to alteration of soluble guanylate cyclase redox regulation.
Topics: Acetylcholine; Animals; Arteries; Blotting, Western; Enzyme Activation; Enzyme Inhibitors; Gene Expr | 2010 |
Neuroprotection against ischemic brain injury conferred by a novel nitrate ester.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cyclic GMP; Dose-Response Relationship, Drug; Guanyl | 2002 |
L-Arginine effects on blood pressure and renal function of intrauterine restricted rats.
Topics: Animals; Arginine; Blood Pressure; Female; Food Deprivation; Glomerular Filtration Rate; Kidney; Kid | 2002 |
Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia.
Topics: Acetylcholine; Animals; Biological Factors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhib | 2005 |
Barrett's esophagus and medications that relax the lower esophageal sphincter.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adult; Age Factors; Aged; Anti-Asthmatic Agents; Barrett E | 2006 |
Treatment with hypotensive agents affects the impaired relaxation of the penile corpus cavernosum in hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carbon Monoxide; Cyclic GMP; Electric | 2006 |
Role of chloride transport proteins in the vasorelaxant action of nitroprusside in isolated rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Cations; Chloride Channels; Chlorides; Culture Media; Cyclic GMP; | 2006 |
Effect of demethylasterriquinone b1 in hypertension associated vascular endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Atorvastatin; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutary | 2007 |
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium | 2008 |
Effects of 4-aminopyridine and tetraethylammonium on relaxant responses of isolated dog coronary arteries to 2-nicotinamidoethyl nitrate (SG-75).
Topics: 4-Aminopyridine; Aminopyridines; Animals; Coronary Vessels; Dinoprost; Dogs; Female; In Vitro Techni | 1982 |
Stereospecific stimulation of coronary vascular PGI2 by organic nitrates--studies with the new compound teopranitol (KC-046).
Topics: Animals; Caffeine; Cattle; Coronary Vessels; Epoprostenol; In Vitro Techniques; Muscle Relaxation; N | 1984 |
Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.
Topics: Animals; Arginine; Cysteine; Dinoprost; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; | 1994 |
Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from nitric oxide formation.
Topics: Animals; In Vitro Techniques; Luminescent Measurements; Male; Methylene Blue; Muscle Contraction; Mu | 1994 |
Endothelium dependence of prostanoid-induced relaxation in human hand veins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Endothelium, Vascular; Female; Hand; Humans; In Vitro Te | 1994 |
Dissimilarity in the mechanisms of action of KRN2391, nicorandil and cromakalim in canine renal artery.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue | 1993 |
Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite.
Topics: Aminoquinolines; Animals; Cattle; Free Radical Scavengers; Glutathione; In Vitro Techniques; Kinetic | 1994 |
CD-832, a new dihydropyridine derivative with both nitrate-like and Ca2+ channel antagonist vasodilator activities.
Topics: Animals; Aorta, Thoracic; Brain Chemistry; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; In Vitr | 1993 |
Activation of distinct cAMP- and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells.
Topics: Aminoquinolines; Animals; Arginine; Cell Separation; Colon; Cyclic AMP; Cyclic GMP; Digestive System | 1993 |
Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic | 1993 |
Specificity of different organic nitrates to elicit NO formation in rabbit vascular tissues and organs in vivo.
Topics: Animals; Aorta; Blood Vessels; Cysteine; Cytochrome P-450 Enzyme System; Dipeptides; Electron Spin R | 1995 |
The formation of nitric oxide donors from peroxynitrite.
Topics: Animals; Aorta, Thoracic; Glucose; Half-Life; Humans; Muscle Relaxation; Muscle, Smooth, Vascular; N | 1995 |
Synthesis and smooth muscle calcium channel antagonist effects of dialkyl 1,4-dihydro-2,6-dimethyl-4-aryl-3,5-pyridinedicarboxylates containing a nitrooxy or nitrophenyl moiety in the 3-alkyl ester substituent.
Topics: Animals; Calcium Channel Blockers; Carboxylic Acids; Esters; Muscle Relaxation; Muscle, Smooth; Nitr | 1996 |
ITF 296, a new endothelium-independent vasodilator: comparison with nitroglycerin and isosorbide dinitrate.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Dru | 1995 |
The nitrate ester ITF 296 relaxes isolated canine arteries and veins.
Topics: Animals; Arteries; Benzoxazines; Dogs; Electrophysiology; Endothelium, Vascular; Female; In Vitro Te | 1995 |
Mechanism of ITF 296-induced vasorelaxation compared to nitroglycerin and isosorbide dinitrate: relationship between relaxation of rabbit aorta and tissue cGMP.
Topics: Animals; Aorta, Thoracic; Benzoxazines; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; In Vitro Techniqu | 1995 |
Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats.
Topics: Animals; Aorta, Thoracic; Cell Adhesion; Cell Communication; Endothelium, Vascular; Ileum; Male; Mes | 1997 |
The effects of peroxynitrite on rat aorta: interaction with glucose and related substances.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Glucose; | 1997 |
Klotho protein protects against endothelial dysfunction.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Cardiovascular System; Disease Models, Animal; Endo | 1998 |
Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Aorta, Thoracic; Cell Survival; Cel | 1998 |
The effect of peroxynitrite on sphincter of Oddi motility.
Topics: Animals; Carbachol; Catalase; Electric Stimulation; Enzyme Inhibitors; Female; Gastrointestinal Moti | 1999 |
Effects of chronic treatment with the spontaneous nitric oxide releaser FK409 on vascular responses in established streptozotocin-induced diabetic rat.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In | 1999 |
Influence of redox compounds on nitrovasodilator-induced relaxations of rat coronary arteries.
Topics: Animals; Coronary Vessels; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; N | 1999 |
Evidence for a feedback inhibition of NO synthesis in enteric synaptosomes via a nitrosothiol intermediate.
Topics: Animals; Feedback; Free Radical Scavengers; Glutathione; Ileum; Male; Muscle Relaxation; Muscle, Smo | 1999 |
Effect of Uncariae ramulus et Uncus on endothelium in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Endothelium, Vascular; In Vitro Techniques; Isometric Contraction; Muscle Co | 1999 |
Effects of atrial and brain natriuretic peptides on lysophosphatidylcholine-mediated endothelial dysfunction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Cattle; Coronary Vessels | 1999 |
Role of nitric oxide in adaptation to hypoxia and adaptive defense.
Topics: Adaptation, Physiological; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; Hypo | 2000 |
Physiological concentration of 17beta-estradiol retards the progression of severe atherosclerosis induced by a high-cholesterol diet plus balloon catheter injury: role of NO.
Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Catheterization; Cholesterol; Cholesterol, Dietary; Cyc | 2000 |
Making and working with peroxynitrite.
Topics: Animals; Calcium; Fluorescent Dyes; Indicators and Reagents; Muscle Relaxation; Muscle, Smooth, Vasc | 1998 |
Prejunctional alpha-adrenoceptors regulate nitrergic neurotransmission in the rabbit urethra.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; | 2000 |
Peroxynitrite produces relaxations on the rat anococcygeus muscle.
Topics: Animals; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Rats | 2000 |
Effect of peroxynitrite on motor function of the opossum esophagus.
Topics: Animals; Enzyme Inhibitors; Esophagitis; Esophagogastric Junction; Female; Guanylate Cyclase; In Vit | 2001 |
The influence of nitric oxide donors on the responses to nitrergic nerve stimulation in the mouse duodenum.
Topics: Animals; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Enzyme Inhibitors; Ethylm | 2001 |
Effects of peroxynitrite on the reactivity of diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; En | 2001 |
Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission.
Topics: Animals; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Iri | 2001 |
Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus.
Topics: Amidines; Animals; Arginine; Benzylamines; Carbachol; Cell Size; DNA, Antisense; Enzyme Inhibitors; | 2001 |
The effect of oxidative stress on endothelium-dependent and nitric oxide donor-induced relaxation: implications for nitrate tolerance.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Glutathione; In Vitro Techniques; Male; Muscle Relaxa | 2002 |
Luminal thrombus disrupts nitric oxide-dependent endothelial physiology.
Topics: Acetylcholine; Animals; Endothelium, Vascular; Factor VIII; Female; Femoral Artery; Iliac Artery; Im | 2002 |
[Study of structural changes in muscle fiber contractile proteins using polarization ultraviolet fluorescent microscopy. IV. Several features of the conformational changes in F-actin during muscle fiber relaxation].
Topics: Acrylamides; Actins; Adenosine Triphosphate; Animals; Calcium; Chemical Phenomena; Chemistry; In Vit | 1978 |
Pharmacodynamic modeling of the in vitro vasodilating effects of organic mononitrates.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Isomerism; Male; Mathematics; Models, Biologi | 1992 |
Total prevention of the development of in vitro tolerance to organic nitrates. Experiments with antioxidants.
Topics: Animals; Antioxidants; Aorta, Thoracic; Drug Tolerance; Female; Guanylate Cyclase; In Vitro Techniqu | 1992 |
Inhibition of nitrovasodilator- and acetylcholine-induced relaxation and cyclic GMP accumulation by the cytochrome P-450 substrate, 7-ethoxyresorufin.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta; Biotransformation; Cyclic GMP; Cytochrome P | 1992 |
The role of nitric oxide in serotonin-induced relaxations in the canine terminal ileum and ileocolonic junction.
Topics: Acetylcholine; Animals; Arginine; Culture Techniques; Dogs; Female; Ileum; Male; Muscle Relaxation; | 1991 |
Differentiation by hydroquinone of relaxations induced by exogenous and endogenous nitrates in non-vascular smooth muscle: role of superoxide anions.
Topics: Animals; Autonomic Nervous System; Guinea Pigs; Hydroquinones; Luminescent Measurements; Male; Metha | 1991 |
Comparison of nicorandil-induced relaxation, elevations of cyclic guanosine monophosphate and stimulation of guanylate cyclase with organic nitrate esters.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Endothelium, Vascular; Enzyme Activa | 1991 |
Vascular nitric oxide-generating activities for organic nitrites and organic nitrates are distinct.
Topics: Amyl Nitrite; Animals; Cattle; Coronary Vessels; Cysteine; Cytosol; Hot Temperature; In Vitro Techni | 1991 |
Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity.
Topics: Animals; Arteries; Cattle; Coronary Vessels; Drug Tolerance; In Vitro Techniques; Isosorbide Dinitra | 1990 |
Substitute anions and the chloride conductance of frog muscle: effects of chlorate and bromate on steady-state values and kinetics.
Topics: Animals; Anions; Bromates; Chlorates; Chlorides; Electric Conductivity; Hydrogen-Ion Concentration; | 1991 |
Spontaneous liberation of nitric oxide cannot account for in vitro vascular relaxation by S-nitrosothiols.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Coronary Vessels; Glutathione; Kinetics; Mercaptoethanol; M | 1990 |
L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; M | 1990 |
Essential role of nitric oxide in descending inhibition in the rat proximal colon.
Topics: Adenosine Triphosphate; Animals; Arginine; Colon; Male; Muscle Relaxation; Neurotensin; Nitrates; Ni | 1990 |
The relaxant action of nicorandil in guinea-pig isolated trachealis.
Topics: Aminophylline; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; | 1986 |
Determinants of in vitro nitroglycerin tolerance induction and reversal: influence of dose regimen, nitrate-free period, and sulfhydryl supplementation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcysteine; Animals; Cattle; | 1989 |
Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.
Topics: Animals; Aorta; Arginine; Biological Assay; Biological Factors; Chemical Phenomena; Chemistry; Endot | 1989 |
The effect of stretch on sarcoplasmic free calcium of frog skeletal muscle at rest.
Topics: Animals; Caffeine; Calcium; Muscle Contraction; Muscle Relaxation; Muscles; Nitrates; Ranidae; Sarco | 1986 |