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nitrates and Multiple Sclerosis, Chronic Progressive

nitrates has been researched along with Multiple Sclerosis, Chronic Progressive in 4 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Multiple Sclerosis, Chronic Progressive: A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)

Research Excerpts

ExcerptRelevanceReference
"Within IFNbeta-1a-treated patients with primary progressive multiple sclerosis, median UNCR values were significantly higher in clinically stable (no Expanded Disability Status Scale change) compared with progressive patients (p = 0."2.75Urinary neopterin and nitric oxide metabolites as markers of interferon beta-1a activity in primary progressive multiple sclerosis. ( Giovannoni, G; Leary, SM; Miller, DH; Petzold, A; Rejdak, K; Thompson, AJ, 2010)
"Patients with DD, AIDS and RA had significantly elevated urinary nitrate plus nitrite (nit : creat."1.30Increased urinary nitric oxide metabolites in patients with multiple sclerosis correlates with early and relapsing disease. ( Elliot, M; Feldmann, M; Giovannoni, G; Heales, SJ; Land, JM; Miller, DH; Miller, RF; O'Riordan, J; Silver, NC; Thompson, EJ, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rejdak, K1
Leary, SM1
Petzold, A1
Thompson, AJ1
Miller, DH2
Giovannoni, G2
Silver, NC1
O'Riordan, J1
Miller, RF1
Heales, SJ1
Land, JM1
Elliot, M1
Feldmann, M1
Thompson, EJ1
Peltola, J1
Ukkonen, M1
Moilanen, E1
Elovaara, I1
Yuceyar, N1
Taşkiran, D1
Sağduyu, A1

Trials

1 trial available for nitrates and Multiple Sclerosis, Chronic Progressive

ArticleYear
Urinary neopterin and nitric oxide metabolites as markers of interferon beta-1a activity in primary progressive multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2010, Volume: 16, Issue:9

    Topics: Adult; Biomarkers; Chromatography, High Pressure Liquid; Colorimetry; Creatinine; Disability Evaluat

2010

Other Studies

3 other studies available for nitrates and Multiple Sclerosis, Chronic Progressive

ArticleYear
Increased urinary nitric oxide metabolites in patients with multiple sclerosis correlates with early and relapsing disease.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1999, Volume: 5, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Arthritis, Rheumatoid; CD4 Lymphocyte Count; Creati

1999
Increased nitric oxide products in CSF in primary progressive MS may reflect brain atrophy.
    Neurology, 2001, Sep-11, Volume: 57, Issue:5

    Topics: Adult; Atrophy; Brain; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; N

2001
Serum and cerebrospinal fluid nitrite and nitrate levels in relapsing-remitting and secondary progressive multiple sclerosis patients.
    Clinical neurology and neurosurgery, 2001, Volume: 103, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Brain; Case-Control Studies; Female; Humans; Magnetic Resonance Imagi

2001