nitrates has been researched along with Migraine Disorders in 12 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess whether migraine patients display a chronic nitric oxide synthase (NOS) hyperactivity by comparing the nitric oxide (NO) production before and following a loading dose of L-arginine between migraine patients (interictally) and matched healthy control subjects." | 2.75 | No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers. ( de Hoon, JN; Depré, M; Van der Schueren, BJ; Van Hecken, A; Verbesselt, R; Verbrugge, FH, 2010) |
| "GW273629 1500 mg was administered to 15 migraine patients both ictally and interictally." | 1.35 | Does the unfavorable pharmacokinetic and pharmacodynamic profile of the iNOS inhibitor GW273629 lead to inefficacy in acute migraine? ( de Hoon, JN; Depré, M; Guillard, F; Laurijssens, BE; Lunnon, MW; Palmer, J; Van der Schueren, BJ; Van Hecken, A; Vanmolkot, FH, 2009) |
| "The connection between migraine and cardiovascular diseases has also drawn attention to the endothelial dysfunctions and NO pathway abnormalities seen in patients with migraine." | 1.35 | Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period. ( Demir, M; Guldiken, B; Guldiken, S; Kabayel, L; Ozkan, H; Tugrul, A; Turgut, N, 2009) |
| "The molecular mechanisms of migraine have not been fully clarified yet." | 1.34 | Increased nitrosative and oxidative stress in platelets of migraine patients. ( Coskun, O; Inan, LE; Sürer, H; Yilmaz, G; Yücel, D, 2007) |
| "A total of 35 consecutive migraine patients without aura who came to gastroenterology polyclinic with various complaints and diagnosed H." | 1.34 | Migraine, Helicobacter pylori, and oxidative stress. ( Adam, B; Ardiçoğlu, Y; Kargili, A; Tunca, A, 2007) |
| "Fifty migraineurs subjects and 25 healthy subjects matched by gender and age were included." | 1.34 | Endothelial function in patients with migraine during the interictal period. ( Flórez, M; Guzmán, JC; López-Jaramillo, P; Morillo, CA; Pradilla, G; Rueda-Clausen, CF; Silva, FA; Silva, SY; Vesga, B; Zarruk, JG, 2007) |
| "Thirty subjects suffering from migraine with and without aura and 20 healthy controls were investigated." | 1.32 | Urinary nitric oxide metabolites and lipid peroxidation by-products in migraine. ( Carolei, A; Ciancarelli, I; Di Massimo, C; Marini, C; Tozzi-Ciancarelli, MG, 2003) |
| "Diet has been implicated as a source of migraine since antiquity." | 1.27 | Diet and headache. Is there a link? ( Diamond, S; Freitag, FG; Prager, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bagherzadi, A | 1 |
| Emani, R | 1 |
| Ghavami, H | 1 |
| Khalkhali, HR | 1 |
| Ebrahimi, M | 1 |
| Van der Schueren, BJ | 2 |
| Lunnon, MW | 1 |
| Laurijssens, BE | 1 |
| Guillard, F | 1 |
| Palmer, J | 1 |
| Van Hecken, A | 2 |
| Depré, M | 2 |
| Vanmolkot, FH | 1 |
| de Hoon, JN | 2 |
| Guldiken, B | 1 |
| Demir, M | 1 |
| Guldiken, S | 1 |
| Turgut, N | 1 |
| Ozkan, H | 1 |
| Kabayel, L | 1 |
| Tugrul, A | 1 |
| Gruber, HJ | 1 |
| Bernecker, C | 1 |
| Pailer, S | 1 |
| Fauler, G | 1 |
| Horejsi, R | 1 |
| Möller, R | 1 |
| Lechner, A | 1 |
| Fazekas, F | 1 |
| Truschnig-Wilders, M | 1 |
| Verbrugge, FH | 1 |
| Verbesselt, R | 1 |
| Ciancarelli, I | 1 |
| Tozzi-Ciancarelli, MG | 1 |
| Di Massimo, C | 1 |
| Marini, C | 1 |
| Carolei, A | 1 |
| Yilmaz, G | 1 |
| Sürer, H | 1 |
| Inan, LE | 1 |
| Coskun, O | 1 |
| Yücel, D | 1 |
| Tunca, A | 1 |
| Ardiçoğlu, Y | 1 |
| Kargili, A | 1 |
| Adam, B | 1 |
| Silva, FA | 1 |
| Rueda-Clausen, CF | 1 |
| Silva, SY | 1 |
| Zarruk, JG | 1 |
| Guzmán, JC | 1 |
| Morillo, CA | 1 |
| Vesga, B | 1 |
| Pradilla, G | 1 |
| Flórez, M | 1 |
| López-Jaramillo, P | 1 |
| Shimomura, T | 1 |
| Murakami, F | 1 |
| Kotani, K | 1 |
| Ikawa, S | 1 |
| Kono, S | 1 |
| Kaube, H | 1 |
| Knight, YE | 1 |
| Storer, RJ | 1 |
| Hoskin, KL | 1 |
| May, A | 1 |
| Goadsby, PJ | 1 |
| Diamond, S | 1 |
| Prager, J | 1 |
| Freitag, FG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838] | Phase 2 | 40 participants (Anticipated) | Interventional | 2009-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for nitrates and Migraine Disorders
| Article | Year |
|---|---|
Comparing the Effect of Heat and Cold Therapy on the Intensity of Nitrate Induced Migraine Type Headache in Cardiac Inpatients: A Randomized Controlled Trial.
Topics: Cryotherapy; Headache; Hot Temperature; Humans; Inpatients; Migraine Disorders; Nitrates; Treatment | 2021 |
No arguments for increased endothelial nitric oxide synthase activity in migraine based on peripheral biomarkers.
Topics: Area Under Curve; Arginine; Biomarkers; Citrulline; Cyclic GMP; Double-Blind Method; Female; Humans; | 2010 |
10 other studies available for nitrates and Migraine Disorders
| Article | Year |
|---|---|
Does the unfavorable pharmacokinetic and pharmacodynamic profile of the iNOS inhibitor GW273629 lead to inefficacy in acute migraine?
Topics: Adult; Area Under Curve; Female; Half-Life; Humans; Male; Migraine Disorders; Nitrates; Nitric Oxide | 2009 |
Asymmetric dimethylarginine and nitric oxide levels in migraine during the interictal period.
Topics: Adult; Arginine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Migraine Diso | 2009 |
Hyperinsulinaemia in migraineurs is associated with nitric oxide stress.
Topics: Adult; Blood Glucose; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Humans; Hyperinsulinism; I | 2010 |
Urinary nitric oxide metabolites and lipid peroxidation by-products in migraine.
Topics: Adult; Brain; Endothelium, Vascular; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Migraine | 2003 |
Increased nitrosative and oxidative stress in platelets of migraine patients.
Topics: Adult; Biomarkers; Blood Platelets; Female; Humans; Male; Malondialdehyde; Migraine Disorders; Nitra | 2007 |
Migraine, Helicobacter pylori, and oxidative stress.
Topics: Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Migraine Disorders; | 2007 |
Endothelial function in patients with migraine during the interictal period.
Topics: Adult; Blood Pressure; Case-Control Studies; Endothelium, Vascular; Female; Forearm; Humans; Male; M | 2007 |
Platelet nitric oxide metabolites in migraine.
Topics: Adult; Blood Platelets; Case-Control Studies; Cyclic GMP; Female; Humans; Male; Migraine Disorders; | 1999 |
Vasodilator agents and supracollicular transection fail to inhibit cortical spreading depression in the cat.
Topics: Animals; Brain Mapping; Cats; Cerebrovascular Circulation; Cortical Spreading Depression; Female; Is | 1999 |
Diet and headache. Is there a link?
Topics: Amines; Caffeine; Diet; Ergot Alkaloids; Ethanol; Food Hypersensitivity; Humans; Hypoglycemia; Migra | 1986 |