Page last updated: 2024-10-19

nitrates and Metaplasia

nitrates has been researched along with Metaplasia in 9 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.

Research Excerpts

ExcerptRelevanceReference
" Because we have previously described that arginase affects NOx content and interferes with the activation of NF-kappaB in lung epithelial cells, the goal of this study was to investigate the impact of arginase inhibition on the bioavailability of NO and the implications for NF-kappaB activation and inflammation in a mouse model of allergic airway disease."1.35Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. ( Ckless, K; Irvin, CG; Janssen-Heininger, YM; Kasahara, D; Lampert, A; Lundblad, LK; Norton, R; Poynter, ME; Reiss, J; van der Vliet, A, 2008)
"Sulfuric acid is an atmospheric pollutant and nitric acid may form locally on the mucosa of lungs exposed to nitrogen dioxide."1.27Acid-induced secretory cell metaplasia in hamster bronchi. ( Breuer, R; Christensen, TG; Lucey, EC; Snider, GL, 1988)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's5 (55.56)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dave, B1
Gonzalez, DD1
Liu, ZB1
Li, X1
Wong, H1
Granados, S1
Ezzedine, NE1
Sieglaff, DH1
Ensor, JE1
Miller, KD1
Radovich, M1
KarinaEtrovic, A1
Gross, SS1
Elemento, O1
Mills, GB1
Gilcrease, MZ1
Chang, JC1
Ckless, K1
Lampert, A1
Reiss, J1
Kasahara, D1
Poynter, ME1
Irvin, CG1
Lundblad, LK1
Norton, R1
van der Vliet, A1
Janssen-Heininger, YM1
Caygill, CP1
Cuello, C1
Correa, P1
Haenszel, W1
Gordillo, G1
Brown, C1
Archer, M1
Tannenbaum, S1
Xu, G1
Song, P1
Reed, PI1
Song, PJ1
Xu, GP1
Sobala, GM1
Pignatelli, B1
Schorah, CJ1
Bartsch, H1
Sanderson, M1
Dixon, MF1
Shires, S1
King, RF1
Axon, AT1
Christensen, TG1
Lucey, EC1
Breuer, R1
Snider, GL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Alpelisib With iNOS Inhibitor and Nab-paclitaxel in Patients With HER2 Negative Metastatic or Locally Advanced Metaplastic Breast Cancer (MpBC)[NCT05660083]Phase 236 participants (Anticipated)Interventional2023-01-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for nitrates and Metaplasia

ArticleYear
Role of RPL39 in Metaplastic Breast Cancer.
    Journal of the National Cancer Institute, 2017, Volume: 109, Issue:6

    Topics: Adenosine Deaminase; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation;

2017
Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Sep-15, Volume: 181, Issue:6

    Topics: Animals; Arginase; Boronic Acids; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enz

2008
ECP-EURONUT intestinal metaplasia study: gastric juice and urine analyses.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1994, Volume: 3 Suppl 2

    Topics: Adult; Bacteria; Case-Control Studies; Europe; Female; Gastric Juice; Humans; Hydrogen-Ion Concentra

1994
ECP-EURONUT-Intestinal Metaplasia Study: urinary and gastric juice analyses.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1994, Volume: 3, Issue:5

    Topics: Adult; Bacteria; Case-Control Studies; Europe; Gastric Acidity Determination; Gastric Juice; Gastric

1994
Gastric cancer in Colombia. I. Cancer risk and suspect environmental agents.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:5

    Topics: Carcinogens, Environmental; Chronic Disease; Colombia; Female; Gastritis; Humans; Intestines; Male;

1976
The relationship between gastric mucosal changes and nitrate intake via drinking water in a high-risk population for gastric cancer in Moping county, China.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1992, Volume: 1, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; China; Diet; Female; Gastric Mucosa; Gastritis; Humans; Male; Metaplasi

1992
[Study on relationship between occurrence of intragastric lesions and drinking water and nitrate intake via water in the inhabitants from a high-risk area for stomach cancer].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1991, Volume: 25, Issue:4

    Topics: Adenocarcinoma; Adult; Female; Gastric Mucosa; Gastritis, Atrophic; Humans; Male; Metaplasia; Middle

1991
Levels of nitrite, nitrate, N-nitroso compounds, ascorbic acid and total bile acids in gastric juice of patients with and without precancerous conditions of the stomach.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Atrophy; Bile Acids and Salts; Gastric Juice; Gastric

1991
Acid-induced secretory cell metaplasia in hamster bronchi.
    Environmental research, 1988, Volume: 45, Issue:1

    Topics: Animals; Bronchi; Cricetinae; Hydrochloric Acid; Lung; Male; Mesocricetus; Metaplasia; Nitrates; Nit

1988