nitrates has been researched along with Melanoma in 13 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our purpose was to determine the maximum tolerated dose and toxicity associated with soluble Chinese hamster ovary [s(CHO)] recombinant human interleukin (IL) 1 receptor (IL-1R; Immunex, Seattle, WA) administration in humans and to determine the effective biological dose and/or maximum tolerated dose of the s(CHO) IL-1R in combination with high-dose IL-2 as determined by reduction in IL-2 toxicity and modulation of its biological effects." | 2.69 | A two-part phase I trial of high-dose interleukin 2 in combination with soluble (Chinese hamster ovary) interleukin 1 receptor. ( Atkins, MB; Clancy, M; Kappler, K; Klempner, M; McDermott, DF; Mier, JW; Rand, W; Ronayne, L; Sorce, D; Trehu, EG, 1998) |
| "Pseudomelanoma is a pathological entity describing the histological findings in cases of recurrences of a partially excised melanocytic nevus, resembling melanoma." | 1.33 | Pseudomelanoma after Solcoderm treatment. ( Amichai, B; Gat, A; Grunwald, MH, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fekkes, D | 1 |
| Van Gool, AR | 1 |
| Bannink, M | 1 |
| Sleijfer, S | 1 |
| Kruit, WH | 1 |
| van der Holt, B | 1 |
| Eggermont, AM | 1 |
| Hengeveld, MW | 1 |
| Stoter, G | 1 |
| Grunwald, MH | 1 |
| Gat, A | 1 |
| Amichai, B | 1 |
| Ferrer, P | 1 |
| Asensi, M | 1 |
| Priego, S | 1 |
| Benlloch, M | 1 |
| Mena, S | 1 |
| Ortega, A | 1 |
| Obrador, E | 1 |
| Esteve, JM | 1 |
| Estrela, JM | 1 |
| Ma, SF | 1 |
| Nishikawa, M | 1 |
| Hyoudou, K | 1 |
| Takahashi, R | 1 |
| Ikemura, M | 1 |
| Kobayashi, Y | 1 |
| Yamashita, F | 1 |
| Hashida, M | 1 |
| Brenner, S | 2 |
| Wolf, R | 1 |
| Michowitz, M | 1 |
| Dascalu, DI | 1 |
| Shafir, R | 1 |
| Azizi, E | 1 |
| Ogilvie, AC | 1 |
| Hack, CE | 1 |
| Wagstaff, J | 1 |
| van Mierlo, GJ | 1 |
| Erenberg, AJ | 1 |
| Thomsen, LL | 1 |
| Hoekman, K | 1 |
| Rankin, EM | 1 |
| Citterio, G | 1 |
| Pellegatta, F | 1 |
| Lucca, GD | 1 |
| Fragasso, G | 1 |
| Scaglietti, U | 1 |
| Pini, D | 1 |
| Fortis, C | 1 |
| Tresoldi, M | 1 |
| Rugarli, C | 1 |
| McDermott, DF | 1 |
| Trehu, EG | 1 |
| Mier, JW | 1 |
| Sorce, D | 1 |
| Rand, W | 1 |
| Ronayne, L | 1 |
| Kappler, K | 1 |
| Clancy, M | 1 |
| Klempner, M | 1 |
| Atkins, MB | 1 |
| Fecker, LF | 1 |
| Eberle, J | 1 |
| Orfanos, CE | 1 |
| Geilen, CC | 1 |
| Goldenhersh, MA | 1 |
| Scheflan, M | 1 |
| Zeligovsky, A | 1 |
| Lahmer, H | 1 |
| Jung, HD | 1 |
3 trials available for nitrates and Melanoma
| Article | Year |
|---|---|
IL-1 beta does not cause neutrophil degranulation but does lead to IL-6, IL-8, and nitrite/nitrate release when used in patients with cancer.
Topics: Adult; Antineoplastic Agents; Cell Degranulation; Complement Activation; Female; Humans; Interleukin | 1996 |
Plasma nitrate plus nitrite changes during continuous intravenous infusion interleukin 2.
Topics: Adult; Aged; Carcinoma, Renal Cell; Cardiovascular Diseases; Drug Administration Schedule; Female; H | 1996 |
A two-part phase I trial of high-dose interleukin 2 in combination with soluble (Chinese hamster ovary) interleukin 1 receptor.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Autoimmunity; C-Reactive Protein; Carcinoma, Renal Cell | 1998 |
10 other studies available for nitrates and Melanoma
| Article | Year |
|---|---|
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interfero | 2009 |
Pseudomelanoma after Solcoderm treatment.
Topics: Acetic Acid; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Copper; Derm | 2006 |
Nitric oxide mediates natural polyphenol-induced Bcl-2 down-regulation and activation of cell death in metastatic B16 melanoma.
Topics: Animals; Cell Adhesion; Cell Death; Cell Line, Tumor; Down-Regulation; Endothelium, Vascular; Flavon | 2007 |
Combining cisplatin with cationized catalase decreases nephrotoxicity while improving antitumor activity.
Topics: Animals; Animals, Outbred Strains; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Catalas | 2007 |
Risk of melanoma after treatment of pigmented lesions with Solcoderm.
Topics: Acetates; Acetic Acid; Adult; Antineoplastic Combined Chemotherapy Protocols; Copper; Dermatologic A | 1993 |
Is Solcoderm a treatment for pigmented lesions?
Topics: Acetates; Acetic Acid; Aged; Antineoplastic Combined Chemotherapy Protocols; Copper; Female; Humans; | 1993 |
Approach to the treatment of pigmented skin lesions.
Topics: Acetates; Acetic Acid; Antineoplastic Combined Chemotherapy Protocols; Copper; Diagnostic Errors; Hu | 1993 |
Inducible nitric oxide synthase is expressed in normal human melanocytes but not in melanoma cells in response to tumor necrosis factor-alpha, interferon-gamma, and lipopolysaccharide.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Enzyme Inhibitors; Gene Expression Regulation, E | 2002 |
Recurrent melanocytic nevi after Solcoderm therapy: a new cause of pseudomelanoma.
Topics: Acetates; Acetic Acid; Adult; Antineoplastic Combined Chemotherapy Protocols; Copper; Diagnosis, Dif | 1992 |
[Experiences of the demonstration of indole melanogens in urine in malignant melanomas].
Topics: Acetates; Catechol Oxidase; Chlorides; Clinical Enzyme Tests; Diagnosis, Differential; Ferricyanides | 1971 |