Page last updated: 2024-10-19

nitrates and Malignant Melanoma

nitrates has been researched along with Malignant Melanoma in 13 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"Our purpose was to determine the maximum tolerated dose and toxicity associated with soluble Chinese hamster ovary [s(CHO)] recombinant human interleukin (IL) 1 receptor (IL-1R; Immunex, Seattle, WA) administration in humans and to determine the effective biological dose and/or maximum tolerated dose of the s(CHO) IL-1R in combination with high-dose IL-2 as determined by reduction in IL-2 toxicity and modulation of its biological effects."2.69A two-part phase I trial of high-dose interleukin 2 in combination with soluble (Chinese hamster ovary) interleukin 1 receptor. ( Atkins, MB; Clancy, M; Kappler, K; Klempner, M; McDermott, DF; Mier, JW; Rand, W; Ronayne, L; Sorce, D; Trehu, EG, 1998)
"Pseudomelanoma is a pathological entity describing the histological findings in cases of recurrences of a partially excised melanocytic nevus, resembling melanoma."1.33Pseudomelanoma after Solcoderm treatment. ( Amichai, B; Gat, A; Grunwald, MH, 2006)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's7 (53.85)18.2507
2000's5 (38.46)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fekkes, D1
Van Gool, AR1
Bannink, M1
Sleijfer, S1
Kruit, WH1
van der Holt, B1
Eggermont, AM1
Hengeveld, MW1
Stoter, G1
Grunwald, MH1
Gat, A1
Amichai, B1
Ferrer, P1
Asensi, M1
Priego, S1
Benlloch, M1
Mena, S1
Ortega, A1
Obrador, E1
Esteve, JM1
Estrela, JM1
Ma, SF1
Nishikawa, M1
Hyoudou, K1
Takahashi, R1
Ikemura, M1
Kobayashi, Y1
Yamashita, F1
Hashida, M1
Brenner, S2
Wolf, R1
Michowitz, M1
Dascalu, DI1
Shafir, R1
Azizi, E1
Ogilvie, AC1
Hack, CE1
Wagstaff, J1
van Mierlo, GJ1
Erenberg, AJ1
Thomsen, LL1
Hoekman, K1
Rankin, EM1
Citterio, G1
Pellegatta, F1
Lucca, GD1
Fragasso, G1
Scaglietti, U1
Pini, D1
Fortis, C1
Tresoldi, M1
Rugarli, C1
McDermott, DF1
Trehu, EG1
Mier, JW1
Sorce, D1
Rand, W1
Ronayne, L1
Kappler, K1
Clancy, M1
Klempner, M1
Atkins, MB1
Fecker, LF1
Eberle, J1
Orfanos, CE1
Geilen, CC1
Goldenhersh, MA1
Scheflan, M1
Zeligovsky, A1
Lahmer, H1
Jung, HD1

Trials

3 trials available for nitrates and Malignant Melanoma

ArticleYear
IL-1 beta does not cause neutrophil degranulation but does lead to IL-6, IL-8, and nitrite/nitrate release when used in patients with cancer.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Jan-01, Volume: 156, Issue:1

    Topics: Adult; Antineoplastic Agents; Cell Degranulation; Complement Activation; Female; Humans; Interleukin

1996
Plasma nitrate plus nitrite changes during continuous intravenous infusion interleukin 2.
    British journal of cancer, 1996, Volume: 74, Issue:8

    Topics: Adult; Aged; Carcinoma, Renal Cell; Cardiovascular Diseases; Drug Administration Schedule; Female; H

1996
A two-part phase I trial of high-dose interleukin 2 in combination with soluble (Chinese hamster ovary) interleukin 1 receptor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:5

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Autoimmunity; C-Reactive Protein; Carcinoma, Renal Cell

1998

Other Studies

10 other studies available for nitrates and Malignant Melanoma

ArticleYear
Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.
    Amino acids, 2009, Volume: 37, Issue:4

    Topics: Adult; Aged; Arginine; Blood Platelets; Carcinoma, Renal Cell; Citrulline; Female; Humans; Interfero

2009
Pseudomelanoma after Solcoderm treatment.
    Melanoma research, 2006, Volume: 16, Issue:5

    Topics: Acetic Acid; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Copper; Derm

2006
Nitric oxide mediates natural polyphenol-induced Bcl-2 down-regulation and activation of cell death in metastatic B16 melanoma.
    The Journal of biological chemistry, 2007, Feb-02, Volume: 282, Issue:5

    Topics: Animals; Cell Adhesion; Cell Death; Cell Line, Tumor; Down-Regulation; Endothelium, Vascular; Flavon

2007
Combining cisplatin with cationized catalase decreases nephrotoxicity while improving antitumor activity.
    Kidney international, 2007, Volume: 72, Issue:12

    Topics: Animals; Animals, Outbred Strains; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Catalas

2007
Risk of melanoma after treatment of pigmented lesions with Solcoderm.
    Dermatology (Basel, Switzerland), 1993, Volume: 187, Issue:3

    Topics: Acetates; Acetic Acid; Adult; Antineoplastic Combined Chemotherapy Protocols; Copper; Dermatologic A

1993
Is Solcoderm a treatment for pigmented lesions?
    Israel journal of medical sciences, 1993, Volume: 29, Issue:10

    Topics: Acetates; Acetic Acid; Aged; Antineoplastic Combined Chemotherapy Protocols; Copper; Female; Humans;

1993
Approach to the treatment of pigmented skin lesions.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:10

    Topics: Acetates; Acetic Acid; Antineoplastic Combined Chemotherapy Protocols; Copper; Diagnostic Errors; Hu

1993
Inducible nitric oxide synthase is expressed in normal human melanocytes but not in melanoma cells in response to tumor necrosis factor-alpha, interferon-gamma, and lipopolysaccharide.
    The Journal of investigative dermatology, 2002, Volume: 118, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Enzyme Inhibitors; Gene Expression Regulation, E

2002
Recurrent melanocytic nevi after Solcoderm therapy: a new cause of pseudomelanoma.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:6 Pt 1

    Topics: Acetates; Acetic Acid; Adult; Antineoplastic Combined Chemotherapy Protocols; Copper; Diagnosis, Dif

1992
[Experiences of the demonstration of indole melanogens in urine in malignant melanomas].
    Zeitschrift fur arztliche Fortbildung, 1971, Mar-15, Volume: 65, Issue:6

    Topics: Acetates; Catechol Oxidase; Chlorides; Clinical Enzyme Tests; Diagnosis, Differential; Ferricyanides

1971