Page last updated: 2024-10-19

nitrates and Liver Steatosis

nitrates has been researched along with Liver Steatosis in 14 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the potential of S-nitroso-N-acetylcysteine (SNAC) in inhibition of lipid peroxidation and the effect of oral SNAC administration in the prevention of nonalcoholic fatty liver disease (NAFLD) in an animal model."7.73Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats. ( Abdalla, DS; Alves, VA; Carrilho, FJ; de Lima, VM; de Oliveira, CP; de Oliveira, MG; Laurindo, FR; Lopasso, FP; Simplicio, FI; Yuahasi, K, 2006)
" l-Arginine improved hepatic arterial and portal blood flows as well as microcirculation in fatty livers (P < 0."3.73The role of nitric oxide in the modulation of hepatic microcirculation and tissue oxygenation in an experimental model of hepatic steatosis. ( Ijaz, S; Seifalian, AM; Winslet, MC; Yang, W, 2005)
"To evaluate the potential of S-nitroso-N-acetylcysteine (SNAC) in inhibition of lipid peroxidation and the effect of oral SNAC administration in the prevention of nonalcoholic fatty liver disease (NAFLD) in an animal model."3.73Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats. ( Abdalla, DS; Alves, VA; Carrilho, FJ; de Lima, VM; de Oliveira, CP; de Oliveira, MG; Laurindo, FR; Lopasso, FP; Simplicio, FI; Yuahasi, K, 2006)
"Nonalcoholic fatty liver disease is a chronic metabolic disorder with significant impact on cardiovascular and liver mortality."1.38Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. ( Bucchieri, F; Bugianesi, E; Galvano, F; Li Volti, G; Mangiameli, A; Marino Gammazza, A; Marino, A; Parola, M; Paternostro, C; Salamone, F; Tibullo, D, 2012)
"In addition, this treatment improved fatty liver, decreased hepatic triglyceride concentration and increased apolipoprotein B100 in liver tissue."1.37Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice. ( Fernández-Moreira, D; García Ruiz, I; García-Consuegra, I; Gómez-Izquierdo, E; Muñoz-Yagüe, T; Solís-Herruzo, JA; Solís-Muñoz, P, 2011)
"The pathogenesis of nonalcoholic steatohepatitis (NASH) is still unclear."1.36Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model. ( Fujita, K; Inamori, M; Iwasaki, T; Kirikoshi, H; Maeyama, S; Nakajima, A; Nozaki, Y; Saito, S; Takahashi, H; Terauchi, Y; Wada, K; Yoneda, M, 2010)
" Amiodarone led to a dose-dependent decrease in cell viability with an LD50 of 50 micromol/L and increased production of superoxide anion and lipid peroxidation."1.34Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity. ( Chabli, A; Colin, P; Elimadi, A; Haddad, PS; Ouazzani-Chahdi, A; Spénard, J, 2007)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's4 (28.57)29.6817
2010's6 (42.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Namwong, A1
Kumphune, S1
Seenak, P1
Chotima, R1
Nernpermpisooth, N1
Malakul, W1
Cordero-Herrera, I1
Kozyra, M1
Zhuge, Z1
McCann Haworth, S1
Moretti, C1
Peleli, M1
Caldeira-Dias, M1
Jahandideh, A1
Huirong, H1
Cruz, JC1
Kleschyov, AL1
Montenegro, MF1
Ingelman-Sundberg, M1
Weitzberg, E1
Lundberg, JO1
Carlstrom, M1
Fujita, K1
Nozaki, Y1
Yoneda, M1
Wada, K1
Takahashi, H1
Kirikoshi, H1
Inamori, M1
Saito, S1
Iwasaki, T1
Terauchi, Y1
Maeyama, S1
Nakajima, A1
Rensen, SS1
Slaats, Y1
Nijhuis, J1
Jans, A1
Bieghs, V1
Driessen, A1
Malle, E1
Greve, JW1
Buurman, WA1
Solís-Muñoz, P1
Solís-Herruzo, JA1
Fernández-Moreira, D1
Gómez-Izquierdo, E1
García-Consuegra, I1
Muñoz-Yagüe, T1
García Ruiz, I1
Tirapelli, LF1
Batalhão, ME1
Jacob-Ferreira, AL1
Tirapelli, DP1
Carnio, EC1
Tanus-Santos, JE1
Queiroz, RH1
Uyemura, SA1
Padovan, CM1
Tirapelli, CR1
Salamone, F1
Galvano, F1
Marino Gammazza, A1
Marino, A1
Paternostro, C1
Tibullo, D1
Bucchieri, F1
Mangiameli, A1
Parola, M1
Bugianesi, E1
Li Volti, G1
Liu, Q1
Rehman, H1
Krishnasamy, Y1
Ramshesh, VK1
Theruvath, TP1
Chavin, KD1
Schnellmann, RG1
Lemasters, JJ1
Zhong, Z1
Ijaz, S1
Yang, W1
Winslet, MC1
Seifalian, AM1
de Oliveira, CP1
Simplicio, FI1
de Lima, VM1
Yuahasi, K1
Lopasso, FP1
Alves, VA1
Abdalla, DS1
Carrilho, FJ1
Laurindo, FR1
de Oliveira, MG1
Ouazzani-Chahdi, A1
Elimadi, A1
Chabli, A1
Spénard, J1
Colin, P1
Haddad, PS1
Aivazian, LK1
Archibald, RW1
Orton, CC1
Schüttmann, W1
Ullmann, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Dapagliflozin on Cardio-Metabolic Risk Factors in Patients With Type-2 Diabetes[NCT03377335]Phase 4186 participants (Anticipated)Interventional2017-12-22Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

14 other studies available for nitrates and Liver Steatosis

ArticleYear
Pineapple fruit improves vascular endothelial dysfunction, hepatic steatosis, and cholesterol metabolism in rats fed a high-cholesterol diet.
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Ananas; Animals; Antioxidants; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Diet; Fatty Liver; Frui

2022
AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 01-02, Volume: 116, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Enzyme Activation; Fatty Liver; Hep G2 Cells; Hepatocytes; H

2019
Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model.
    Alcoholism, clinical and experimental research, 2010, Volume: 34 Suppl 1

    Topics: Amino Acids; Animals; Blotting, Western; Choline; Choline Deficiency; Diet; Disease Models, Animal;

2010
Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis.
    The American journal of pathology, 2009, Volume: 175, Issue:4

    Topics: Adult; Alcohols; Biomarkers; Cell Count; Chemokines, CXC; Fatty Liver; Female; Humans; Hypochlorous

2009
Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice.
    Journal of pineal research, 2011, Volume: 51, Issue:1

    Topics: Animals; Blotting, Western; Body Weight; Electron Transport Chain Complex Proteins; Fatty Liver; His

2011
Chronic ethanol consumption induces histopathological changes and increases nitric oxide generation in the rat liver.
    Tissue & cell, 2011, Volume: 43, Issue:6

    Topics: Animals; Biomarkers; Ethanol; Fatty Liver; Gene Expression; Liver; Male; Malondialdehyde; Metallopro

2011
Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:4

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline Deficiency; Cytokines; Di

2012
Role of inducible nitric oxide synthase in mitochondrial depolarization and graft injury after transplantation of fatty livers.
    Free radical biology & medicine, 2012, Jul-15, Volume: 53, Issue:2

    Topics: Adenosine; Alanine Transaminase; Allopurinol; Amidines; Animals; Benzylamines; Bilirubin; Caspase 3;

2012
The role of nitric oxide in the modulation of hepatic microcirculation and tissue oxygenation in an experimental model of hepatic steatosis.
    Microvascular research, 2005, Volume: 70, Issue:3

    Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Cholesterol; Electron Transpor

2005
Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats.
    World journal of gastroenterology, 2006, Mar-28, Volume: 12, Issue:12

    Topics: Acetylcysteine; Administration, Oral; Animals; Disease Models, Animal; Fatty Liver; Lipid Peroxidati

2006
Combining ursodeoxycholic acid or its NO-releasing derivative NCX-1000 with lipophilic antioxidants better protects mouse hepatocytes against amiodarone toxicity.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:2

    Topics: Amiodarone; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Cells, Cultured; Dose-Re

2007
[Morphologic studies in the toxicologic and hygienic evaluation of nitrates].
    Gigiena i sanitariia, 1986, Issue:11

    Topics: Animals; Dose-Response Relationship, Drug; Fatty Liver; Liver; Nitrates; Rats

1986
Specific identification of free and esterified fatty acids in tissue sections.
    The Histochemical journal, 1970, Volume: 2, Issue:5

    Topics: Adipose Tissue; Animals; Dioxins; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Histocytoche

1970
[Effect of nitro lac solvents on the liver].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1973, Volume: 19, Issue:3

    Topics: Chemical and Drug Induced Liver Injury; Coloring Agents; Environmental Exposure; Fatty Liver; Female

1973