nitrates has been researched along with Left Ventricular Dysfunction in 39 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To specifically assess the synthetic activity of the L-arginine-NO metabolic pathway, urinary excretion of [15N]nitrates and [15N]urea was determined after a primed continuous intravenous infusion of L-[15N]arginine (40 micromol/kg) in 16 patients with congestive heart failure and 9 age-matched normal control subjects at rest and during submaximal treadmill exercise." | 7.70 | Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure. ( Katz, SD; Khan, T; Knecht, M; Mathew, L; Potharlanka, P; Whelan, J; Zeballos, GA, 1999) |
| " NO bioavailability was assessed using cyclic guanosine monophosphate quantification." | 5.37 | Atorvastatin worsens left ventricular diastolic dysfunction and endothelial dysfunction of epicardial coronary arteries in normocholesterolemic porcine with left ventricular hypertrophy. ( Aubin, MC; Carrier, M; Forcillo, J; Maltais, S; Perrault, LP; Shi, YF; Tardif, JC, 2011) |
| "To specifically assess the synthetic activity of the L-arginine-NO metabolic pathway, urinary excretion of [15N]nitrates and [15N]urea was determined after a primed continuous intravenous infusion of L-[15N]arginine (40 micromol/kg) in 16 patients with congestive heart failure and 9 age-matched normal control subjects at rest and during submaximal treadmill exercise." | 3.70 | Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure. ( Katz, SD; Khan, T; Knecht, M; Mathew, L; Potharlanka, P; Whelan, J; Zeballos, GA, 1999) |
| " Here, we tested the hypotheses that doxorubicin causes left ventricular dysfunction in mice and is associated with dysregulation of nitric oxide in cardiac tissue, leading to the accumulation of 3-nitrotyrosine (a biomarker of peroxynitrite formation)." | 3.70 | Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice. ( Bauer, JA; Mihm, MJ; Weinstein, DM, 2000) |
| "Ivabradine is a new selective HR-lowering agent that selectively inhibits the pacemaker current I (f) in the sinus atrial node." | 2.45 | Ivabradine: beyond heart rate control. ( D'Orazio, N; Riccioni, G; Vitulano, N, 2009) |
| " Chronic use of other inotropic drugs for congestive left heart failure is not recommended." | 2.39 | [Chronic left heart ventricle failure and inotropic stimulation]. ( Dickstein, K; Gundersen, T; Hole, T; Kjekshus, J; Myhre, ES; Rønnevik, P; Smith, P; Westheim, A, 1995) |
| " NO bioavailability was assessed using cyclic guanosine monophosphate quantification." | 1.37 | Atorvastatin worsens left ventricular diastolic dysfunction and endothelial dysfunction of epicardial coronary arteries in normocholesterolemic porcine with left ventricular hypertrophy. ( Aubin, MC; Carrier, M; Forcillo, J; Maltais, S; Perrault, LP; Shi, YF; Tardif, JC, 2011) |
| " Vascular reactivity was assessed in isolated hypertrophied hearts (55+/-3 days after aortic banding or sham operation) by constructing dose-response curves to acetylcholine (ACh), sodium nitroprusside (SNP) and adenosine." | 1.31 | Endogenous and exogenous coronary vasodilatation are attenuated in cardiac hypertrophy: a morphological defect? ( Bovill, E; Flores, NA; Kingsbury, MP; Sheridan, DJ; Turner, MA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (30.77) | 18.2507 |
| 2000's | 17 (43.59) | 29.6817 |
| 2010's | 9 (23.08) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Sharifov, OF | 1 |
| Denney, TS | 1 |
| Girard, AA | 1 |
| Gupta, H | 1 |
| Lloyd, SG | 1 |
| Patel, JN | 1 |
| Shah, SJ | 1 |
| Chirinos, JA | 1 |
| Beck, DT | 1 |
| Martin, JS | 1 |
| Casey, DP | 1 |
| Avery, JC | 1 |
| Sardina, PD | 1 |
| Braith, RW | 1 |
| Iskandar, MZ | 1 |
| Quasem, W | 1 |
| El-Omar, M | 1 |
| Hirai, DM | 1 |
| Zelt, JT | 1 |
| Jones, JH | 1 |
| Castanhas, LG | 1 |
| Bentley, RF | 1 |
| Earle, W | 1 |
| Staples, P | 1 |
| Tschakovsky, ME | 1 |
| McCans, J | 1 |
| O'Donnell, DE | 1 |
| Neder, JA | 1 |
| Riccioni, G | 1 |
| Vitulano, N | 1 |
| D'Orazio, N | 1 |
| Zhang, H | 1 |
| Morgan, B | 1 |
| Potter, BJ | 1 |
| Ma, L | 1 |
| Dellsperger, KC | 1 |
| Ungvari, Z | 1 |
| Zhang, C | 1 |
| Forcillo, J | 1 |
| Maltais, S | 1 |
| Aubin, MC | 1 |
| Shi, YF | 1 |
| Carrier, M | 1 |
| Tardif, JC | 1 |
| Perrault, LP | 1 |
| Jacoby, D | 1 |
| Albajrami, O | 1 |
| Bellumkonda, L | 1 |
| Raja, S | 1 |
| Singh, B | 1 |
| Rohit, MK | 1 |
| Manohar, K | 1 |
| Kashyap, R | 1 |
| Bhattacharya, A | 1 |
| Mittal, BR | 1 |
| Staudt, A | 1 |
| Böhm, M | 1 |
| Knebel, F | 1 |
| Grosse, Y | 1 |
| Bischoff, C | 1 |
| Hummel, A | 1 |
| Dahm, JB | 1 |
| Borges, A | 1 |
| Jochmann, N | 1 |
| Wernecke, KD | 1 |
| Wallukat, G | 1 |
| Baumann, G | 1 |
| Felix, SB | 1 |
| Gnanasegaram, D | 1 |
| Argall, J | 1 |
| He, ZX | 1 |
| Yang, MF | 1 |
| Liu, XJ | 1 |
| Shi, RF | 1 |
| Gao, RL | 1 |
| Hu, SS | 1 |
| Wu, QY | 1 |
| Yang, YJ | 1 |
| Chen, JL | 1 |
| Levine, TB | 1 |
| Levine, AB | 1 |
| Bolenbaugh, J | 1 |
| Green, PR | 1 |
| Giorgetti, A | 1 |
| Pingitore, A | 1 |
| Favilli, B | 1 |
| Kusch, A | 1 |
| Lombardi, M | 1 |
| Marzullo, P | 1 |
| Entok, E | 1 |
| Cavusoglu, Y | 1 |
| Kaya, E | 1 |
| Vardareli, E | 1 |
| Timuralp, B | 1 |
| Slart, RH | 1 |
| Agool, A | 1 |
| van Veldhuisen, DJ | 1 |
| Dierckx, RA | 1 |
| Bax, JJ | 1 |
| Djaballah, W | 1 |
| Muller, MA | 1 |
| Angioï, M | 1 |
| Moulin, F | 1 |
| Codreanu, A | 1 |
| Mandry, D | 1 |
| Ethevenot, G | 1 |
| Karcher, G | 1 |
| Aliot, E | 1 |
| Marie, PY | 1 |
| Acampa, W | 1 |
| Evangelista, L | 1 |
| Sorrentino, AR | 1 |
| Petretta, M | 1 |
| Luongo, L | 1 |
| Cuocolo, A | 1 |
| Myhre, ES | 1 |
| Gundersen, T | 1 |
| Dickstein, K | 1 |
| Hole, T | 1 |
| Kjekshus, J | 1 |
| Rønnevik, P | 1 |
| Smith, P | 1 |
| Westheim, A | 1 |
| Branzi, A | 1 |
| Maggioni, AP | 1 |
| Pajak, A | 1 |
| Sciagrà, R | 4 |
| Bisi, G | 3 |
| Santoro, GM | 2 |
| Zerauschek, F | 1 |
| Sestini, S | 1 |
| Pedenovi, P | 1 |
| Pappagallo, R | 1 |
| Fazzini, PF | 1 |
| Oyama, Ji | 1 |
| Shimokawa, H | 2 |
| Momii, H | 2 |
| Cheng, X | 1 |
| Fukuyama, N | 2 |
| Arai, Y | 1 |
| Egashira, K | 2 |
| Nakazawa, H | 2 |
| Takeshita, A | 2 |
| Kronenberg, MW | 1 |
| Konstam, MA | 1 |
| Edens, TR | 1 |
| Howe, DM | 1 |
| Dolan, N | 1 |
| Udelson, JE | 1 |
| Benedict, C | 1 |
| Stewart, D | 1 |
| Yusuf, S | 1 |
| Katz, SD | 1 |
| Khan, T | 1 |
| Zeballos, GA | 1 |
| Mathew, L | 1 |
| Potharlanka, P | 1 |
| Knecht, M | 1 |
| Whelan, J | 1 |
| Soeki, T | 1 |
| Fukuda, N | 1 |
| Shinohara, H | 1 |
| Takeichi, N | 1 |
| Tanaka, H | 1 |
| Bando, K | 1 |
| Yui, Y | 1 |
| Tamura, Y | 1 |
| Cheng, XS | 1 |
| Oyama, J | 1 |
| Fonseca, C | 1 |
| Kingsbury, MP | 1 |
| Turner, MA | 1 |
| Flores, NA | 1 |
| Bovill, E | 1 |
| Sheridan, DJ | 1 |
| Weinstein, DM | 1 |
| Mihm, MJ | 1 |
| Bauer, JA | 1 |
| Pellegri, M | 1 |
| Pupi, A | 3 |
| Bolognese, L | 1 |
| Carnovale, V | 1 |
| Johnson, A | 1 |
| Mackway-Jones, K | 1 |
| Iwase, M | 1 |
| Yokota, M | 1 |
| Kitaichi, K | 1 |
| Wang, L | 1 |
| Takagi, K | 1 |
| Nagasaka, T | 1 |
| Izawa, H | 1 |
| Hasegawa, T | 1 |
| Leoncini, M | 2 |
| Marcucci, G | 2 |
| Dabizzi, RP | 1 |
| Cannizzaro, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nitrite Supplementation to Mitigate Fatigability and Increase Function in Long COVID Patients[NCT05618574] | Phase 3 | 40 participants (Anticipated) | Interventional | 2023-12-01 | Recruiting | ||
| Multicentre, Randomized, Double-blind, Prospective Investigation on the Effects of Immunoadsorption on Cardiac Function in Patients With Dilated Cardiomyopathy[NCT00558584] | 200 participants (Anticipated) | Interventional | 2007-12-31 | Completed | |||
| [NCT00000516] | Phase 3 | 0 participants | Interventional | 1985-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for nitrates and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Ivabradine: beyond heart rate control.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzazepines; Calcium Channel Blockers; Cardiovascular | 2009 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Buccal nitrates in left ventricular failure.
Topics: Administration, Oral; Evidence-Based Medicine; Heart Failure; Humans; Injections, Intravenous; Nitra | 2003 |
[Chronic left heart ventricle failure and inotropic stimulation].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cal | 1995 |
[Clinical and diagnostic indications for the use of nitrates in dynamic heart defects (decompensation, left ventricular dysfunction without decompensation, etc].
Topics: Heart Failure; Humans; Nitrates; Vasodilator Agents; Ventricular Dysfunction, Left | 1996 |
[The role of nitrates in left ventricular insufficiency in patients with acute myocardial infarction].
Topics: Humans; Multicenter Studies as Topic; Myocardial Infarction; Nitrates; Randomized Controlled Trials | 1996 |
Treating diastolic failure: the role of diuretics and nitrates.
Topics: Diastole; Diuretics; Drug Therapy, Combination; Heart Failure; Humans; Nitrates; Ventricular Dysfunc | 1999 |
8 trials available for nitrates and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Enhanced external counterpulsation improves endothelial function and exercise capacity in patients with ischaemic left ventricular dysfunction.
Topics: Aged; Angina Pectoris; Brachial Artery; Coronary Artery Disease; Counterpulsation; Epoprostenol; Exe | 2014 |
Dietary nitrate supplementation and exercise tolerance in patients with heart failure with reduced ejection fraction.
Topics: Dietary Supplements; Double-Blind Method; Exercise Test; Exercise Tolerance; Heart Failure; Humans; | 2017 |
Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoantibodies; Calc | 2002 |
Baseline/postnitrate tetrofosmin SPECT for myocardial viability assessment in patients with postischemic severe left ventricular dysfunction: new evidence from MRI.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Exercise Test; Female; Gadolinium DTPA; Heart; Human | 2005 |
Detection of hibernate myocardium by 99mTc sestamibi gated SPECT during low-dose dobutamine infusion plus nitrate in patients with first acute myocardial infarction.
Topics: Adult; Aged; Dobutamine; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infar | 2005 |
Nitrate administration increases blood flow in dysfunctional but viable myocardium, leading to improved assessment of myocardial viability: A PET study.
Topics: Aged; Blood Flow Velocity; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Myocardium; Ni | 2006 |
Factors influencing exercise performance in patients with left ventricular dysfunction. SOLVD Investigators. Studies of Left Ventricular Dysfunction.
Topics: Adult; Aged; Blood Pressure; Digitalis Glycosides; Diuretics; Double-Blind Method; Exercise; Exercis | 1998 |
Technetium-99m sestamibi imaging to predict left ventricular ejection fraction outcome after revascularisation in patients with chronic coronary artery disease and left ventricular dysfunction: comparison between baseline and nitrate-enhanced imaging.
Topics: Adult; Aged; Chronic Disease; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Image Proc | 2001 |
25 other studies available for nitrates and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Coronary artery disease is associated with impaired atrial function regardless of left ventricular filling pressure.
Topics: Aged; Atrial Function, Left; Coronary Artery Disease; Humans; Middle Aged; Nitrates; Stroke Volume; | 2023 |
Inorganic vs. organic nitrates for heart failure with preserved ejection fraction: it's not all in your head!
Topics: Heart Failure; Humans; Nitrates; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Function, | 2017 |
The Nitrate-Nitrite-NO Pathway as a Novel Therapeutic Target in Heart Failure with Reduced Ejection Fraction.
Topics: Heart Failure; Humans; Nitrates; Nitrites; Stroke Volume; Ventricular Dysfunction, Left | 2018 |
5-Fluorouracil cardiotoxicity: reversible left ventricular systolic dysfunction with early detection.
Topics: Adult; Antimetabolites, Antineoplastic; Calcium Channel Blockers; Cardiotoxicity; Colonic Neoplasms; | 2015 |
Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.
Topics: Animals; Antioxidants; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Magnetic Resonance | 2010 |
Atorvastatin worsens left ventricular diastolic dysfunction and endothelial dysfunction of epicardial coronary arteries in normocholesterolemic porcine with left ventricular hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Atorvastatin; Coronary Vessels; Cyclic GMP; Dose-Response Relationsh | 2011 |
Natural history of end-stage LV dysfunction: has it improved from the classic Franciosa and Cohn Graph?
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiac Resynch | 2011 |
Comparison of nitrate augmented Tc-99m tetrofosmin gated SPECT imaging with FDG PET imaging for the assessment of myocardial viability in patients with severe left ventricular dysfunction.
Topics: Adult; Aged; Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; Coronary Artery Dise | 2012 |
Association of myocardial viability on nitrate-augmented technetium-99m hexakis-2-methoxylisobutyl isonitrile myocardial tomography and intermediate-term outcome in patients with prior myocardial infarction and left ventricular dysfunction.
Topics: Aged; Disease-Free Survival; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nitrates; Out | 2003 |
Reversal of heart failure remodeling: is it maintained?
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiomyopathies; Echocardiography; Female | 2003 |
Nitrate-enhanced gated SPECT in patients with primary angioplasty for acute myocardial infarction: evidence of a reversible and nitrate-sensitive impairment of myocardial perfusion.
Topics: Angioplasty, Balloon, Coronary; Evidence-Based Medicine; Female; Humans; Image Enhancement; Male; Mi | 2007 |
Single-photon emission computed tomography after nitrate administration predicts cardiac events in patients with previous myocardial infarction and left ventricular dysfunction.
Topics: Echocardiography, Stress; Female; Health Status; Health Status Indicators; Humans; Male; Middle Aged | 2007 |
[Relationship between myocardial ischemia and left ventricular dysfunction].
Topics: Angiotensin-Converting Enzyme Inhibitors; Humans; Myocardial Infarction; Myocardial Ischemia; Nitrat | 1994 |
[Myocardial infarction--risks and procedures. Longitudinal observation of a population of 280,000 women and men--Project POL-MONICA Krakow. I V: Prognosis of non-invasive treatment in myocardial infarction within 28 days since its onset].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Confidence Inter | 1996 |
Comparison of baseline-nitrate technetium-99m sestamibi with rest-redistribution thallium-201 tomography in detecting viable hibernating myocardium and predicting postrevascularization recovery.
Topics: Adult; Aged; Female; Heart; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Revasculari | 1997 |
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart; | 1998 |
Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure.
Topics: Adult; Aged; Arginine; Cardiomyopathies; Creatinine; Exercise Test; Female; Heart Failure; Humans; L | 1999 |
[Hypertensive heart disease with left ventricular diastolic dysfunction demonstrating restrictive hemodynamics: a case report].
Topics: Atrial Natriuretic Factor; Calcium Channel Blockers; Coronary Circulation; Diastole; Diuretics; Echo | 1999 |
Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo.
Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Dogs; Echocardiography; Female; Interleukin | 1999 |
Endogenous and exogenous coronary vasodilatation are attenuated in cardiac hypertrophy: a morphological defect?
Topics: Animals; Coronary Circulation; Coronary Vessels; Guinea Pigs; Hyperemia; Hypertrophy, Left Ventricul | 2000 |
Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice.
Topics: Animals; Antibiotics, Antineoplastic; Creatine Kinase; Doxorubicin; Immunohistochemistry; Male; Mice | 2000 |
Prognostic implications of Tc-99m sestamibi viability imaging and subsequent therapeutic strategy in patients with chronic coronary artery disease and left ventricular dysfunction.
Topics: Aged; Angioplasty, Balloon, Coronary; Cardiovascular Agents; Chronic Disease; Coronary Disease; Fema | 2000 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Frusemide or nitrates in acute left ventricular failure.
Topics: Aged; Aged, 80 and over; Evidence-Based Medicine; Furosemide; Heart Failure; Humans; Male; Nitrates; | 2001 |
Cardiac functional and structural alterations induced by endotoxin in rats: importance of platelet-activating factor.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Echocardiography; Electrocardiography | 2001 |
Predicting revascularization outcome in patients with coronary artery disease and left ventricular dysfunction (data from the SEMINATOR study).
Topics: Coronary Disease; Discriminant Analysis; Echocardiography; Female; Humans; Male; Middle Aged; Myocar | 2002 |