nitrates has been researched along with Kidney Failure, Chronic in 45 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proteinuria was significantly lower in L-arginine-treated animals from week 24 onward (p<0." | 5.32 | Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure. ( Albrecht, EW; Smit-van Oosten, A; Stegeman, CA; van Goor, H, 2003) |
| "Patients with essential hypertension (n = 24) were administered a low-salt diet (2 g NaCl/day), a high-salt diet (20-23 g) and then a low-salt diet for 7 days, and plasma levels of nitrate and nitrite (NOx) and asymmetric dimethylarginine (ADMA) were examined." | 5.10 | Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease. ( Fujiwara, N; Nakamura, M; Okumura, K; Osanai, T; Osawa, H; Saitoh, M; Sasaki, S; Tomita, H; Yamabe, H, 2002) |
| "Supplementation with L-arginine (ARG) strikingly ameliorates proteinuria and glomerulosclerosis in remnant rats by overcoming nitric oxide (NO) deficiency." | 5.09 | Randomized, double-blind, placebo-controlled study of arginine supplementation in chronic renal failure. ( Andreucci, M; Andreucci, VE; Bellizzi, V; Capuano, A; Cianciaruso, B; Corso, G; De Nicola, L; Garibotto, G; Minutolo, R, 1999) |
| " L-arginine has been used to improve endothelial function by increasing nitric oxide (NO) bioavailability and in animal models this in turn has attenuated the progression of atherosclerosis." | 2.70 | Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure. ( Bennett-Richards, KJ; Bruckdorfer, KR; Deanfield, JE; Donald, AE; Kattenhorn, M; Oakley, GR; Rees, L; Varghese, Z, 2002) |
| "In ND and HD, reactive hyperemia as well as %NTG and %FMD were attenuated to a similar degree." | 2.70 | Impairment of vascular responses to reactive hyperemia and nitric oxide in chronic renal failure. ( Hiraoka, K; Inoue, T; Ishigami, Y; Izumi, M; Nakanishi, T; Otaki, Y; Takamitsu, Y, 2002) |
| "We hypothesized that in patients with chronic renal failure, a condition associated with both hyperhomocysteinemia and atherosclerosis, treatment with folic acid would improve endothelial function." | 2.69 | Does folic acid decrease plasma homocysteine and improve endothelial function in patients with predialysis renal failure? ( Jones, HJ; Landray, MJ; McGlynn, FJ; Thambyrajah, J; Townend, JN; Wheeler, DC, 2000) |
| "FE(NO )values of ESRD patients were similar to normals, while EBC-NOx, NO2-, NH3+ and pH were significantly higher in ESRD patients compared to normals (EBC-NOx 12." | 1.35 | Breath analysis in patients with end-stage renal disease: effect of haemodialysis. ( Bagnis, C; Bommarito, L; Bruno, M; Bugiani, M; Ferrero, N; Guida, G; Heffler, E; Petrarulo, M; Rolla, G, 2008) |
| "Proteinuria was significantly lower in L-arginine-treated animals from week 24 onward (p<0." | 1.32 | Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure. ( Albrecht, EW; Smit-van Oosten, A; Stegeman, CA; van Goor, H, 2003) |
| "Patients with ADPKD have defective nitric oxide generation from diminished cNOS activity." | 1.32 | Endothelial dysfunction and reduced nitric oxide in resistance arteries in autosomal-dominant polycystic kidney disease. ( Iversen, J; Strandgaard, S; Wang, D; Wilcox, CS, 2003) |
| "Whether rHuEpo treatment in ESRD is accompanied by alterations in NO production was explored in patients undergoing hemodialysis." | 1.31 | Biphasic changes in nitric oxide generation in hemodialyzed patients with end-stage renal disease treated with recombinant human erythropoietin. ( Acchiardo, SR; Cardenas, R; Kang, ES; Mishra, S; Tevlin, MT; Wang, YB, 2000) |
| "Patients with chronic renal failure had a higher exhaled nitric oxide concentration [39+/-3 versus 19+/-1 parts per billion, (mean+/-S." | 1.30 | Increased excretion of nitric oxide in exhaled air of patients with chronic renal failure. ( Hirata, Y; Kakoki, M; Matsumoto, A; Momomura, Si; Nagata, D; Omata, M; Sugimoto, T; Tagawa, H, 1999) |
| "It is concluded that chronic renal failure in rats is a low nitric oxide production state." | 1.29 | Oral administration of L-arginine and captopril in rats prevents chronic renal failure by nitric oxide production. ( Ashab, I; Blum, M; Cabili, S; Chernihovsky, T; Hassner, A; Iaina, A; Peer, G; Schwartz, D; Silverberg, D; Wollman, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 10 (22.22) | 18.2507 |
| 2000's | 27 (60.00) | 29.6817 |
| 2010's | 4 (8.89) | 24.3611 |
| 2020's | 2 (4.44) | 2.80 |
| Authors | Studies |
|---|---|
| Heredia Martinez, A | 1 |
| Rosa Diez, G | 1 |
| Ferraris, V | 1 |
| Coccia, PA | 1 |
| Ferraris, JR | 1 |
| Checa, A | 1 |
| Wheelock, CE | 1 |
| Lundberg, JO | 1 |
| Weitzberg, E | 1 |
| Carlström, M | 1 |
| Krmar, RT | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 7 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 1 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
| Stancill, JS | 1 |
| Happ, JT | 1 |
| Broniowska, KA | 1 |
| Hogg, N | 1 |
| Corbett, JA | 1 |
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| Bi, YL | 1 |
| Fan, Y | 2 |
| Sun, YB | 1 |
| Wang, AL | 1 |
| Xiao, BH | 1 |
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| Wáng, YXJ | 1 |
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| Chu, S | 1 |
| Pan, Q | 1 |
| Li, D | 2 |
| Zheng, S | 2 |
| Ma, L | 1 |
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| Ge, X | 1 |
| Xie, K | 1 |
| Lei, P | 1 |
| Dias-Santagata, D | 1 |
| Lennerz, JK | 1 |
| Sadow, PM | 1 |
| Frazier, RP | 1 |
| Govinda Raju, S | 1 |
| Henry, D | 1 |
| Chung, T | 1 |
| Kherani, J | 1 |
| Rothenberg, SM | 1 |
| Wirth, LJ | 1 |
| Marti, CN | 1 |
| Choi, NG | 1 |
| Bae, SJ | 1 |
| Ni, L | 1 |
| Luo, X | 1 |
| Dai, T | 1 |
| Yang, Y | 3 |
| Lee, R | 1 |
| Fleischer, AS | 1 |
| Wemhoff, AP | 1 |
| Ford, CR | 1 |
| Kleppinger, EL | 1 |
| Helms, K | 1 |
| Bush, AA | 1 |
| Luna-Abanto, J | 1 |
| García Ruiz, L | 1 |
| Laura Martinez, J | 1 |
| Álvarez Larraondo, M | 1 |
| Villoslada Terrones, V | 1 |
| Dukic, L | 1 |
| Maric, N | 1 |
| Simundic, AM | 1 |
| Chogtu, B | 1 |
| Ommurugan, B | 1 |
| Thomson, SR | 1 |
| Kalthur, SG | 1 |
| Benidir, M | 1 |
| El Massoudi, S | 1 |
| El Ghadraoui, L | 1 |
| Lazraq, A | 1 |
| Benjelloun, M | 1 |
| Errachidi, F | 1 |
| Cassar, M | 1 |
| Law, AD | 1 |
| Chow, ES | 1 |
| Giebultowicz, JM | 1 |
| Kretzschmar, D | 1 |
| Salonurmi, T | 1 |
| Nabil, H | 1 |
| Ronkainen, J | 1 |
| Hyötyläinen, T | 1 |
| Hautajärvi, H | 1 |
| Savolainen, MJ | 1 |
| Tolonen, A | 1 |
| Orešič, M | 1 |
| Känsäkoski, P | 1 |
| Rysä, J | 1 |
| Hakkola, J | 1 |
| Hukkanen, J | 1 |
| Zhu, N | 1 |
| Li, Y | 4 |
| Du, Q | 1 |
| Hao, P | 1 |
| Cao, X | 1 |
| Li, CX | 1 |
| Zhao, S | 1 |
| Luo, XM | 1 |
| Feng, JX | 1 |
| Gonzalez-Cotto, M | 1 |
| Guo, L | 1 |
| Karwan, M | 1 |
| Sen, SK | 1 |
| Barb, J | 1 |
| Collado, CJ | 1 |
| Elloumi, F | 1 |
| Palmieri, EM | 1 |
| Boelte, K | 1 |
| Kolodgie, FD | 1 |
| Finn, AV | 1 |
| Biesecker, LG | 1 |
| McVicar, DW | 1 |
| Qu, F | 1 |
| Deng, Z | 1 |
| Xie, Y | 2 |
| Tang, J | 3 |
| Chen, Z | 2 |
| Luo, W | 1 |
| Xiong, D | 1 |
| Zhao, D | 1 |
| Fang, J | 1 |
| Zhou, Z | 1 |
| Niu, PP | 1 |
| Song, B | 1 |
| Xu, YM | 1 |
| Zhang, Z | 2 |
| Qiu, N | 1 |
| Yin, J | 1 |
| Zhang, J | 4 |
| Guo, W | 1 |
| Liu, M | 2 |
| Liu, T | 2 |
| Chen, D | 5 |
| Luo, K | 1 |
| He, Z | 2 |
| Zheng, G | 1 |
| Xu, F | 1 |
| Sun, W | 1 |
| Yin, F | 1 |
| van Hest, JCM | 1 |
| Du, L | 2 |
| Shi, X | 1 |
| Kang, S | 1 |
| Duan, W | 1 |
| Zhang, S | 2 |
| Feng, J | 2 |
| Qi, N | 1 |
| Shen, G | 1 |
| Ren, H | 1 |
| Shang, Q | 1 |
| Zhao, W | 2 |
| Yang, Z | 2 |
| Jiang, X | 2 |
| Alame, M | 1 |
| Cornillot, E | 1 |
| Cacheux, V | 1 |
| Tosato, G | 1 |
| Four, M | 1 |
| De Oliveira, L | 1 |
| Gofflot, S | 1 |
| Delvenne, P | 1 |
| Turtoi, E | 1 |
| Cabello-Aguilar, S | 1 |
| Nishiyama, M | 1 |
| Turtoi, A | 1 |
| Costes-Martineau, V | 1 |
| Colinge, J | 1 |
| Guo, Q | 1 |
| Quan, M | 1 |
| Dong, J | 1 |
| Bai, J | 1 |
| Han, R | 1 |
| Cai, Y | 1 |
| Lv, YQ | 1 |
| Chen, Q | 1 |
| Lyu, HD | 1 |
| Deng, L | 1 |
| Zhou, D | 1 |
| Xiao, X | 1 |
| De Langhe, S | 1 |
| Billadeau, DD | 1 |
| Lou, Z | 1 |
| Zhang, JS | 1 |
| Xue, Z | 1 |
| Shen, XD | 1 |
| Gao, F | 1 |
| Busuttil, RW | 1 |
| Kupiec-Weglinski, JW | 1 |
| Ji, H | 1 |
| Otano, I | 1 |
| Alvarez, M | 1 |
| Minute, L | 1 |
| Ochoa, MC | 1 |
| Migueliz, I | 1 |
| Molina, C | 1 |
| Azpilikueta, A | 1 |
| de Andrea, CE | 1 |
| Etxeberria, I | 1 |
| Sanmamed, MF | 1 |
| Teijeira, Á | 1 |
| Berraondo, P | 1 |
| Melero, I | 1 |
| Zhong, Z | 1 |
| Xie, X | 1 |
| Yu, Q | 1 |
| Zhou, C | 1 |
| Liu, C | 2 |
| Liu, W | 1 |
| Chen, W | 1 |
| Yin, Y | 1 |
| Li, CW | 1 |
| Hsu, JL | 1 |
| Zhou, Q | 1 |
| Hu, B | 1 |
| Fu, P | 1 |
| Atyah, M | 1 |
| Ma, Q | 2 |
| Xu, Y | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nebivolol Effect on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients[NCT01157234] | Phase 4 | 32 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant[NCT01239472] | Phase 4 | 30 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?[NCT00291720] | Phase 2 | 120 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Absolute Change in Diastolic Blood Pressure (DBP), (millimeter, Mercury)= Month-12 sitting trough Diastolic Blood Pressure (millimeter, Mercury) level minus baseline sitting trough Diastolic Blood Pressure (millimeter, Mercury). (NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | millimeter, mercury (Least Squares Mean) |
|---|---|
| Nebivolol | -0.66 |
| Metoprolol | -2.35 |
The changed percentage in Estimated Glomerular Filtration Rate (eGFR), (based on the Modification of Diet in Renal Disease Equation)=[Month-12 GFR level minus baseline eGFR level] divided by [baseline eGFR level] multiplied by 100, where all levels are in ml/min. (NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol | 2.16 |
| Metoprolol | 10.43 |
"Absolute change in Mean Arterial Blood Pressure, (MAP), (millimeter, Mercury= Month-12 sitting trough MAP minus baseline sitting trough MAP.~Mean Arterial Pressure= 2/3 trough diastolic blood pressure + 1/3 trough systolic blood pressure" (NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | millimeter, Mercury (Least Squares Mean) |
|---|---|
| Nebivolol | -1.07 |
| Metoprolol | -3.19 |
Percent change in quantity of Anti-Hypertensive Drug Classes (AHDC)=[Month-12 absolute number of AHDC minus baseline absolute number of AHDC] divided by [baseline absolute number of AHDC] multiplied by 100. (NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol | -8.14 |
| Metoprolol | 8.70 |
(NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol < 50 Years Old | 51.55 |
| Metoprolol <50 Years Old | -16.64 |
(NCT01157234)
Timeframe: Baseline and Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol <50 Year Old | 51.55 |
| Metoprolol >/= 50 Year Old | -17.99 |
(NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol >/=50 Years Old | -15.25 |
| Metoprolol >/=50 Years Old | -17.99 |
(NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol >/=50 Years Old | -15.25 |
| Metoprolol <50 Years Old | -16.64 |
(NCT01157234)
Timeframe: 12 Months
| Intervention | nmol/L (Least Squares Mean) |
|---|---|
| Nebivolol | 50.07 |
| Metoprolol | 38.13 |
Percent change in Nitric Oxide (NO) blood level (nmol/L)=[Month-12 NO blood level minus baseline NO blood level] divided by [baseline NO blood level] multiplied by 100, where all levels are in nmol/L. (NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | percent change (Least Squares Mean) |
|---|---|
| Nebivolol | 11.47 |
| Metoprolol | -17.27 |
Absolute change in Systolic Blood Pressure (SBP), (millimeter, Mercury)=Month-12 sitting trough SBP level minus baseline sitting trough SBP level (NCT01157234)
Timeframe: Change in Baseline, Month-12
| Intervention | millimeter, Mercury (Least Squares Mean) |
|---|---|
| Nebivolol | -2.65 |
| Metoprolol | -3.88 |
Cd106(VCAM-1) , IP-10/CXCL10, MIG/CXCL9, MCP-1/CCL2, IL-1, RANTES, IL-8, IL12p70, TNF, IL-10, IL-6, IL-1, VEGF, FGF, CD54(ICAM-1) were analysed in urine 90 days after transplant (before randomization), and 365 days after transplant. Material were conserved at -80 Celsius, and analysed by ELISA at same time. Data was shown in MFI units (NCT01239472)
Timeframe: Urine and biopsy data are collected 90 days and 365 days after transplant.
| Intervention | MFI (Median) | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IP10 90days | IP10 365days | MCP1 90days | MCP1 365days | MIG 90days | MIG 365days | RANTES 90days | RANTES 365days | IL8 90days | IL8 365days | IL12 90days | IL12 365days | TNF 90days | TNF 365days | IL10 90days | IL10 365 days | IL6 90days | IL6 365days | IL1 90days | IL1 365days | VEGF 90days | VEGF 365days | FGF 90days | FGF 365days | CD106 90days | CD106 365days | CD54 90days | CD54 365days | |
| Everolimus | 893 | 147 | 4119 | 1375 | 433 | 580 | 145 | 155 | 624 | 435 | 124 | 124 | 146 | 157 | 164 | 182 | 349 | 262 | 215 | 228 | 70 | 45 | 43 | 29 | 28564 | 19614 | 1293 | 1664 |
| Tacrolimus | 380 | 763 | 2349 | 1306 | 396 | 287 | 148 | 144 | 495 | 641 | 116 | 124 | 136 | 153 | 155 | 179 | 282 | 281 | 212 | 228 | 82 | 84 | 39 | 30 | 43222 | 18324 | 1512 | 696 |
Evaluation of renal function (serum creatinine) 90 days after transplant and 365 days after transplant. (NCT01239472)
Timeframe: 90 days after transplant and 365 days after transplant
| Intervention | mg/dL (Median) | |
|---|---|---|
| Cr 90days | Cr 365days | |
| Everolimus | 1.3 | 1.4 |
| Tacrolimus | 1.6 | 1.4 |
1 review available for nitrates and Kidney Failure, Chronic
9 trials available for nitrates and Kidney Failure, Chronic
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Changes in oxidative stress in renal graft patients receiving calcineurin inhibitors: cyclosporine versus tacrolimus.
Topics: Adult; Antioxidants; Ascorbic Acid; Calcineurin Inhibitors; Cyclosporine; Enzyme Inhibitors; Female; | 2012 |
Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease.
Topics: Arginine; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Failure, Chr | 2002 |
Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure.
Topics: Administration, Oral; Adolescent; Arginine; Arteriosclerosis; Child; Cross-Over Studies; Dietary Sup | 2002 |
Impairment of vascular responses to reactive hyperemia and nitric oxide in chronic renal failure.
Topics: Blood Pressure; Creatinine; Cysteine; Endothelium, Vascular; Female; Glutathione; Homocysteine; Huma | 2002 |
Randomized, double-blind, placebo-controlled study of arginine supplementation in chronic renal failure.
Topics: Adolescent; Adult; Amino Acids; Arginine; Cyclic GMP; Double-Blind Method; Female; Glomerular Filtra | 1999 |
Does folic acid decrease plasma homocysteine and improve endothelial function in patients with predialysis renal failure?
Topics: Aged; Brachial Artery; Double-Blind Method; Endothelium, Vascular; Erythrocytes; Female; Folic Acid; | 2000 |
Methylene blue, a nitric oxide inhibitor, prevents haemodialysis hypotension.
Topics: Adult; Aged; Blood Platelets; Blood Pressure; Diastole; Enzyme Inhibitors; Humans; Hypotension; Kidn | 2001 |
[Distribution of electrolytes and substances normally contained in urine in the extracellular space under dialysis].
Topics: Ascitic Fluid; Creatinine; Electrolytes; Extracellular Space; Humans; Kidney Failure, Chronic; Nitra | 1968 |
36 other studies available for nitrates and Kidney Failure, Chronic
| Article | Year |
|---|---|
"Removal of nitrate and nitrite by hemodialysis in end-stage renal disease and by sustained low-efficiency dialysis in acute kidney injury".
Topics: Acute Kidney Injury; Adult; Child; Cross-Sectional Studies; Female; Humans; Kidney Failure, Chronic; | 2020 |
Using GIS Mapping to Track Hot Spots of Kidney Disease in California.
Topics: California; Geographic Information Systems; Geography, Medical; Groundwater; Humans; Kidney Failure, | 2020 |
Diosgenin improves vascular function by increasing aortic eNOS expression, normalize dyslipidemia and ACE activity in chronic renal failure rats.
Topics: Animals; Antioxidants; Aorta; Diosgenin; Dyslipidemias; Endothelium, Vascular; Glutathione; Kidney; | 2013 |
Breath analysis in patients with end-stage renal disease: effect of haemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Ammonia; Biomarkers; Breath Tests; Case-Control Studies; Female; Hum | 2008 |
Elevation of serum apelin-13 is positively correlated with ADMA in patients on maintenance hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Female; Humans; Intercellular Signaling Peptid | 2009 |
Endothelin-1, big endothelin-1, and nitric oxide in patients with chronic renal disease and hypertension.
Topics: Adult; Endothelin-1; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitra | 2009 |
Appetite-regulating hormones in chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Appetite; Body Mass Index; Cross-Sectional Studies; Enzyme-Linked Immunosor | 2011 |
Reduced nitric oxide synthase activity in rats with chronic renal disease due to glomerulonephritis.
Topics: Animals; Antibodies; Arginine; Autoantibodies; Blood Urea Nitrogen; Creatinine; Glomerulonephritis; | 2002 |
Association of renal injury with nitric oxide deficiency in aged SHR: prevention by hypertension control with AT1 blockade.
Topics: Aging; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arterioles; Hypertension, | 2002 |
Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure.
Topics: Animals; Arginine; Blood Pressure; Creatine; Dietary Supplements; Disease Models, Animal; Glomerulos | 2003 |
Endothelial dysfunction and reduced nitric oxide in resistance arteries in autosomal-dominant polycystic kidney disease.
Topics: Adult; Arginine; Arteries; Endothelium, Vascular; Female; Humans; Hypertension; Kidney Failure, Chro | 2003 |
Endothelial dysfunction in patients with kidney failure and vascular risk factors: acute effects of hemodialysis.
Topics: Adult; Aged; Biomarkers; Blood Pressure; Cyclic GMP; Diastole; Endothelium, Vascular; Female; Homocy | 2004 |
Evidence for generation of the precarcinogen nitrosodimethylamine in the small intestine in chronic renal failure.
Topics: Bacteria; Cocarcinogenesis; Dimethylnitrosamine; Duodenum; Gastric Mucosa; Humans; Kidney Failure, C | 1983 |
Oral administration of L-arginine and captopril in rats prevents chronic renal failure by nitric oxide production.
Topics: Administration, Oral; Animals; Arginine; Blood Pressure; Captopril; Creatinine; Female; Kidney Failu | 1995 |
Peritoneal nitric oxide is a marker of peritonitis in patients on continuous ambulatory peritoneal dialysis.
Topics: Acinetobacter Infections; Adult; Aged; Biomarkers; Dialysis Solutions; Female; Humans; Kidney Failur | 1996 |
Nitric oxide (NO) modulates the neurogenic control of blood pressure in rats with chronic renal failure (CRF).
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Brain; Creatinine; Enzyme Inhibitors; Gene | 1997 |
Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Free Radicals; Humans; Kidney Failure, | 1997 |
Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans.
Topics: Adult; Aged; Alleles; Coronary Disease; Female; Genetic Markers; Genotype; Humans; Kidney Failure, C | 1998 |
Enhanced production of nitric oxide may be involved in acute hypotension during maintenance hemodialysis.
Topics: Acute Disease; Anions; Blood Pressure; Cyclic GMP; Endothelin-1; Female; Heart Rate; Humans; Hypoten | 1998 |
Increased excretion of nitric oxide in exhaled air of patients with chronic renal failure.
Topics: Analysis of Variance; Atrial Natriuretic Factor; Breath Tests; Chi-Square Distribution; Cyclic GMP; | 1999 |
Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis.
Topics: Adult; Aged; Arginine; Citrulline; Creatinine; Cyclic GMP; Female; Humans; Hypertension, Renal; Kidn | 1999 |
Nitric oxide metabolites in decompensated liver cirrhosis.
Topics: Adult; Aged; Angina Pectoris; Female; Hemoglobins; Humans; Kidney Failure, Chronic; Liver Cirrhosis; | 1999 |
Increased plasma adrenomedullin levels in hemodialysis patients with sustained hypotension.
Topics: Adrenomedullin; Adult; Blood Pressure; Blood Volume; Female; Humans; Hypotension; Interleukin-1; Iod | 2000 |
Role of nitric oxide in haemodialysis hypotension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged | 2000 |
Biphasic changes in nitric oxide generation in hemodialyzed patients with end-stage renal disease treated with recombinant human erythropoietin.
Topics: Blood Pressure; Body Weight; Erythropoietin; Female; Heart Rate; Humans; Kidney Failure, Chronic; Ma | 2000 |
Erythropoietin does not affect nitric oxide system in rats with chronic renal failure.
Topics: Acetylcholine; Anemia; Animals; Aorta, Thoracic; Body Weight; Erythropoietin; Hypertension, Renal; I | 2000 |
Effect of hemodialysis on plasma nitric oxide levels.
Topics: Colorimetry; Cyclic GMP; Female; Follow-Up Studies; Humans; Inflammation Mediators; Kidney Failure, | 2000 |
Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure.
Topics: Adenoviridae; Animals; Blood Pressure; Blood Urea Nitrogen; Cardiomegaly; Cyclic GMP; Fibrosis; Gene | 2000 |
Temporal changes of cytokines and nitric oxide products in urine from renal transplant patients.
Topics: Acute Disease; Adult; Creatinine; Cyclic GMP; Cytokines; Female; Follow-Up Studies; Graft Rejection; | 2000 |
Alteration in plasma antioxidant capacities in chronic renal failure and hemodialysis patients: a possible explanation for the increased cardiovascular risk in these patients.
Topics: Aged; Analysis of Variance; Antioxidants; Ascorbic Acid; Cardiovascular Diseases; Case-Control Studi | 2000 |
Total nitric oxide production is low in patients with chronic renal disease.
Topics: Adult; Aged; Arginine; Blood Pressure; Creatinine; Female; Humans; Hypertension, Renal; Kidney Failu | 2000 |
Decreased nitric oxide synthesis in rats with chronic renal failure.
Topics: Animals; Aorta, Thoracic; Enzyme Induction; Isoenzymes; Kidney; Kidney Failure, Chronic; Male; Nephr | 2000 |
Reversible sequestration of nitric oxide by hemoglobin during hemodialysis in end-stage renal disease.
Topics: Anemia; Arginine; Erythropoietin; Hematocrit; Hemoglobins; Humans; Hypotension; Kidney Failure, Chro | 2001 |
Urinary excretion of vasoactive substances in chronic renal failure.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Creatinine; Cyclic GMP; Endothelin-1; Female; Humans; Kid | 2001 |
Enhanced nitric oxide inactivation and protein nitration by reactive oxygen species in renal insufficiency.
Topics: alpha-Tocopherol; Animals; Antioxidants; Arginine; Creatinine; Endothelium, Vascular; Kidney Failure | 2002 |
The evaluation of oxidative stress in patients with chronic renal failure.
Topics: Adult; Blood Urea Nitrogen; Creatinine; Dialysis; Female; Humans; Kidney Failure, Chronic; Male; Mal | 2002 |