Page last updated: 2024-10-19

nitrates and Kidney Diseases

nitrates has been researched along with Kidney Diseases in 55 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the association between nephropathy and oxidative stress, by measurement of systolic blood pressure, lipid peroxidation, activities of catalase, manganese- and copper-zinc-superoxide dismutase and endothelial nitric oxide synthase expression and concentrations of nitrates/nitrites in kidneys from rats with Metabolic Syndrome."3.75Association of renal damage and oxidative stress in a rat model of metabolic syndrome. Influence of gender. ( Baños, G; Diaz-Diaz, E; El Hafidi, M; Pérez-Torres, I; Roque, P, 2009)
"Single injection of a small quantity of phenol into the cortex of one kidney in rats results in development of persistent hypertension (HTN) which is thought to be mediated by activation of renal afferent and efferent sympathetic pathways and sodium retention."3.74Effect of renal injury-induced neurogenic hypertension on NO synthase, caveolin-1, AKt, calmodulin and soluble guanylate cyclase expressions in the kidney. ( Bai, Y; Campese, V; Mortazavi, R; Vaziri, ND; Ye, S, 2007)
" However, nipradilol, at doses of 10 and 15 mg/kg/day, significantly decreased proteinuria and glomerulosclerosis, while propranolol did not."3.72A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol. ( Hasuike, Y; Hiraoka, K; Inoue, T; Itahana, R; Izumi, M; Miyagawa, K; Nakanishi, T; Nishihara, F; Takamitsu, Y, 2003)
" We investigated the factors involved in the development of hypertension induced by LPD in rats with post-cyclosporine (CsA) nephropathy, and determined the appropriate composition for LPD that is to be utilized for renal research."3.72Factors involved in the development of hypertension induced by a low-protein diet in rats with renal injury. ( Endoh, M; Ikegaya, N; Kumagai, H; Odamaki, M, 2004)
"Twenty-one days after 5/6 nephrectomy, after the onset of hypertension and overt proteinuria, rats were divided in 3 groups (N= 7-8) and given daily by gavage: vehicle, the vasopeptidase inhibitor AVE7688 (3 mg/kg bid), or enalapril (5 mg/kg bid) until day 90."3.72Vasopeptidase inhibitor restores the balance of vasoactive hormones in progressive nephropathy. ( Benigni, A; Corna, D; Longaretti, L; Maggioni, P; Noris, M; Remuzzi, G; Rottoli, D; Todeschini, M; Zatelli, C; Zoja, C, 2004)
"Effects of aging and dietary protein on the L-arginine-nitric oxide (Arg-NO) pathway and the progress of chronic nephropathy were examined."3.69L-arginine-nitric oxide pathway and chronic nephropathy in aged rats. ( Futami, Y; Maki, T; Sonaka, I, 1994)
"Pharmacokinetic studies were conducted in 8 patients with disseminated neoplasms refractory to conventional chemotherapy, who received gallium nitrate at doses of 300 to 600 mg/m2 intravenously in a phase I clinical trial."3.66Kinetics of gallium nitrate, a new anticancer agent. ( Bedikian, AY; Benjamin, RS; Hall, SW; Loo, TL; Stewart, D; Valdivieso, M; Yeung, K, 1979)
" Its primary dose-limiting side effect is nephrotoxicity."1.42Betaine supplementation mitigates cisplatin-induced nephrotoxicity by abrogation of oxidative/nitrosative stress and suppression of inflammation and apoptosis in rats. ( Hagar, H; Medany, AE; Medany, GE; Nayal, OA; Salam, R, 2015)
" Nevertheless, animal and clinical studies have demonstrated that nephrotoxicity is the major adverse effect limiting the prolonged CsA therapeutic use."1.39Sildenafil protects against nitric oxide deficiency-related nephrotoxicity in cyclosporine A treated rats. ( Abdel-latif, RG; El-Moselhy, MA; Khalifa, MA; Morsy, MA, 2013)
" Chronic administration of L-NAME significantly increased renal HSP70 and TBARS levels and decreased renal SOD activity and serum nitrites/nitrates."1.39Protective effect of aerobic exercise against L-NAME-induced kidney damage in rats. ( Azarbayjani, MA; Habibian, M; Hedayati, M; Peeri, M, 2013)
" Chronic administration of L-NAME for 8 wk induced hypertension and renal injury and reduced the blood iron-nitrosyl-hemoglobin level (control 38."1.35Dietary doses of nitrite restore circulating nitric oxide level and improve renal injury in L-NAME-induced hypertensive rats. ( Ishizawa, K; Izawa, Y; Kagami, S; Kanematsu, Y; Kawazoe, K; Kondo, S; Motobayashi, Y; Ohnishi, H; Tamaki, T; Tomita, S; Tsuchiya, K; Yamaguchi, K, 2008)
" The modulation of NO was done by chronic administration of L-arginine (NO donor) or N(w)-nitro-L-arginine, a known nitric oxide synthase inhibitor."1.31Glomerular basement membrane anionic sites in adriamycin nephropathy: effect of saline loading and nitric oxide modulation. ( Blum, M; Cabili, S; Chernichovsky, T; Fish, R; Hertzan-Levy, S; Iaina, A; Polak-Charcon, S; Schwartz, D; Skutelsky, E; Wollman, Y, 2000)
"Clearances of inulin and PAH decreased progressively after CsA dosage while renal vascular resistance increased."1.31Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? ( Bernemann, A; Bickeböller, R; Gossmann, J; Raab, HP; Radounikli, A; Schellinski, O; Scheuermann, EH, 2001)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199011 (20.00)18.7374
1990's5 (9.09)18.2507
2000's25 (45.45)29.6817
2010's13 (23.64)24.3611
2020's1 (1.82)2.80

Authors

AuthorsStudies
Li, X1
Zhuge, Z1
Carvalho, LRRA1
Braga, VA1
Lucena, RB1
Li, S1
Schiffer, TA1
Han, H1
Weitzberg, E1
Lundberg, JO1
Carlström, M1
Mooney, JJ1
Abdel-latif, RG1
Morsy, MA1
El-Moselhy, MA1
Khalifa, MA1
Peeri, M1
Habibian, M1
Azarbayjani, MA1
Hedayati, M1
Gado, AM1
Aldahmash, BA1
Hagar, H1
Medany, AE1
Salam, R1
Medany, GE1
Nayal, OA1
Yasmeen, G1
Dawani, ML1
Mahboob, T1
Patil, CN1
Wallace, K1
LaMarca, BD1
Moulana, M1
Lopez-Ruiz, A1
Soljancic, A1
Juncos, LA1
Grande, JP1
Reckelhoff, JF1
Kanematsu, Y1
Yamaguchi, K1
Ohnishi, H1
Motobayashi, Y1
Ishizawa, K1
Izawa, Y1
Kawazoe, K1
Kondo, S1
Kagami, S1
Tomita, S1
Tsuchiya, K1
Tamaki, T1
Yoh, K1
Hirayama, A1
Ishizaki, K1
Yamada, A1
Takeuchi, M1
Yamagishi, S1
Morito, N1
Nakano, T1
Ojima, M1
Shimohata, H1
Itoh, K1
Takahashi, S1
Yamamoto, M1
Pérez-Torres, I1
Roque, P1
El Hafidi, M1
Diaz-Diaz, E1
Baños, G1
Zakrzewicz, D1
Zakrzewicz, A1
Wilker, S1
Boedeker, RH1
Padberg, W1
Eickelberg, O1
Grau, V1
Nicholson, SS1
Griffin, K1
Polichnowski, A1
Licea-Vargas, H1
Picken, M1
Long, J1
Williamson, G1
Bidani, A1
Elks, CM1
Reed, SD1
Mariappan, N1
Shukitt-Hale, B1
Joseph, JA1
Ingram, DK1
Francis, J1
Yamaleyeva, LM1
Lindsey, SH1
Varagic, J1
Zhang, LL1
Gallagher, PE1
Chen, AF1
Chappell, MC1
Hagar, HH1
Abd El Tawab, R1
Takamitsu, Y1
Nakanishi, T1
Nishihara, F1
Hasuike, Y1
Izumi, M1
Inoue, T1
Hiraoka, K1
Itahana, R1
Miyagawa, K1
BALAZS, T1
HATCH, A1
ZAWIDZKA, Z1
GRICE, HC1
PORTE, A2
CUSSAC, Y2
STOEBNER, P2
ZAHND, JP1
BATZENSCHLAGER, A1
Endoh, M1
Odamaki, M1
Ikegaya, N1
Kumagai, H1
Neto, JS1
Nakao, A1
Kimizuka, K1
Romanosky, AJ1
Stolz, DB1
Uchiyama, T1
Nalesnik, MA1
Otterbein, LE1
Murase, N1
Benigni, A1
Zoja, C1
Zatelli, C1
Corna, D1
Longaretti, L1
Rottoli, D1
Maggioni, P1
Todeschini, M1
Noris, M1
Remuzzi, G1
Abdelrahman, M1
Mazzon, E1
Bauer, M1
Bauer, I1
Delbosc, S1
Cristol, JP1
Patel, NS1
Cuzzocrea, S1
Thiemermann, C1
Pedraza-Chaverrí, J1
Barrera, D1
Medina-Campos, ON1
Carvajal, RC1
Hernández-Pando, R1
Macías-Ruvalcaba, NA1
Maldonado, PD1
Salcedo, MI1
Tapia, E1
Saldívar, L1
Castilla, ME1
Ibarra-Rubio, ME1
Wu, L1
Tiwari, MM1
Messer, KJ1
Holthoff, JH1
Gokden, N1
Brock, RW1
Mayeux, PR1
Bai, Y1
Ye, S1
Mortazavi, R1
Campese, V1
Vaziri, ND1
Kakoki, M1
McGarrah, RW1
Kim, HS1
Smithies, O1
Namikoshi, T1
Tomita, N1
Fujimoto, S1
Haruna, Y1
Ohzeki, M1
Komai, N1
Sasaki, T1
Yoshida, A1
Kashihara, N1
Higashino, H1
Miya, H1
Mukai, H1
Miya, Y1
Amudha, G1
Josephine, A1
Sudhahar, V1
Varalakshmi, P1
Ma, SF1
Nishikawa, M1
Hyoudou, K1
Takahashi, R1
Ikemura, M1
Kobayashi, Y1
Yamashita, F1
Hashida, M1
Aleisa, AM1
Al-Majed, AA1
Al-Yahya, AA1
Al-Rejaie, SS1
Bakheet, SA1
Al-Shabanah, OA1
Sayed-Ahmed, MM1
Hwang, WS1
Chen, SH1
Lin, CH1
Chang, HK1
Chen, WC1
Lin, MT1
Samoĭlov, AP1
Belianina, TV1
Korshun, MN1
Sonaka, I1
Futami, Y1
Maki, T1
Assis, SM1
Monteiro, JL1
Seguro, AC1
Satoh, M1
Aoki, Y1
Tohyama, C1
Vodovotz, Y1
Kopp, JB1
Takeguchi, H1
Shrivastav, S1
Coffin, D1
Lucia, MS1
Mitchell, JB1
Webber, R1
Letterio, J1
Wink, D1
Roberts, AB1
Kurioka, S1
Koshimura, K1
Sugitani, M1
Murakami, Y1
Nishiki, M1
Kato, Y1
Hertzan-Levy, S1
Fish, R1
Skutelsky, E1
Wollman, Y1
Chernichovsky, T1
Polak-Charcon, S1
Schwartz, D1
Blum, M1
Cabili, S1
Iaina, A1
Bank, N1
Kiroycheva, M1
Singhal, PC1
Anthony, GM1
Southan, GJ1
Szabo, C1
Barton, M1
Lattmann, T1
d'Uscio, LV1
Lüscher, TF1
Shaw, S1
Gossmann, J1
Radounikli, A1
Bernemann, A1
Schellinski, O1
Raab, HP1
Bickeböller, R1
Scheuermann, EH1
Büyükafşar, K1
Yazar, A1
Düşmez, D1
Oztürk, H1
Polat, G1
Levent, A1
Hosogai, N1
Seki, J1
Goto, T1
Longoni, B1
Migliori, M1
Ferretti, A1
Origlia, N1
Panichi, V1
Boggi, U1
Filippi, C1
Cuttano, MG1
Giovannini, L1
Mosca, F1
Hall, SW1
Yeung, K1
Benjamin, RS1
Stewart, D1
Valdivieso, M1
Bedikian, AY1
Loo, TL1
Shub, C1
Vlietstra, RE1
McGoon, MD1
Anghelova, O1
al-Khayyat, AA1
Aronson, AL1
Gyrd-Hansen, N1
Dovat, VN1
Obradović, D1
Stanković, J1
Hardy, TL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Interaction of Polymorphism rs35652124 With Curcumin Supplementation on NFE2L2 Gene Expression, Antioxidant Capacity and Renal Function in Patients With Early Diabetic Nephropathy[NCT03262363]Phase 2/Phase 3176 participants (Anticipated)Interventional2018-08-01Not yet recruiting
The Health Effects of a Blueberry Enriched Diet on Obese Children: A Feasibility Study[NCT01809795]10 participants (Actual)Interventional2013-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrates and Kidney Diseases

ArticleYear
Selection of optimal drug therapy for the patient with angina pectoris.
    Mayo Clinic proceedings, 1985, Volume: 60, Issue:8

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel

1985

Trials

1 trial available for nitrates and Kidney Diseases

ArticleYear
Association of high-density lipoprotein cholesterol with improvement of endothelial dysfunction recovery in renovascular disease.
    Iranian journal of kidney diseases, 2015, Volume: 9, Issue:1

    Topics: Adult; Atorvastatin; Biomarkers; Cholesterol, HDL; Delayed-Action Preparations; Drug Therapy, Combin

2015

Other Studies

53 other studies available for nitrates and Kidney Diseases

ArticleYear
Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway.
    Redox biology, 2022, Volume: 51

    Topics: AMP-Activated Protein Kinases; Animals; Female; Fibrosis; Humans; Kidney; Kidney Diseases; Lipid Met

2022
Letter to the editor: Dietary nitrates may reduce cardiorenal side-effects of lithium therapy in older subjects.
    Journal of psychiatric research, 2019, Volume: 114

    Topics: Aged; Antidepressive Agents; Diet; Heart Diseases; Humans; Kidney Diseases; Lithium; Middle Aged; Ni

2019
Sildenafil protects against nitric oxide deficiency-related nephrotoxicity in cyclosporine A treated rats.
    European journal of pharmacology, 2013, Apr-05, Volume: 705, Issue:1-3

    Topics: Albuminuria; Animals; Catalase; Creatinine; Cyclosporine; Glutathione; Immunosuppressive Agents; Kid

2013
Protective effect of aerobic exercise against L-NAME-induced kidney damage in rats.
    Arhiv za higijenu rada i toksikologiju, 2013, Volume: 64, Issue:2

    Topics: Animals; Cytoprotection; Down-Regulation; HSP70 Heat-Shock Proteins; Kidney; Kidney Diseases; Lipid

2013
Antioxidant effect of Arabic gum against mercuric chloride-induced nephrotoxicity.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Administration, Oral; Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Gum Arabic; Injections

2013
Betaine supplementation mitigates cisplatin-induced nephrotoxicity by abrogation of oxidative/nitrosative stress and suppression of inflammation and apoptosis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2015, Volume: 67, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Betaine; Cisplatin; Dietary Supplements; Immunohistochemi

2015
Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration.
    American journal of physiology. Renal physiology, 2016, 08-01, Volume: 311, Issue:2

    Topics: Animals; Creatine; Cytokines; Enzyme Inhibitors; Interleukin-10; Kidney; Kidney Diseases; Male; NG-N

2016
Dietary doses of nitrite restore circulating nitric oxide level and improve renal injury in L-NAME-induced hypertensive rats.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:5

    Topics: Administration, Oral; Animals; Blood Pressure; Body Weight; Diet; Glycated Hemoglobin; Hypertension;

2008
Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice.
    Genes to cells : devoted to molecular & cellular mechanisms, 2008, Volume: 13, Issue:11

    Topics: Animals; Electron Spin Resonance Spectroscopy; Female; Guanosine; Hyperglycemia; Kidney Diseases; Mi

2008
Association of renal damage and oxidative stress in a rat model of metabolic syndrome. Influence of gender.
    Free radical research, 2009, Volume: 43, Issue:8

    Topics: Animals; Catalase; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Hormone Replacement T

2009
Dimethylarginine metabolism during acute and chronic rejection of rat renal allografts.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:1

    Topics: Acute Disease; Animals; Arginine; Blotting, Western; Chronic Disease; Graft Rejection; Immunoenzyme

2011
Southeastern plants toxic to ruminants.
    The Veterinary clinics of North America. Food animal practice, 2011, Volume: 27, Issue:2

    Topics: Anemia, Aplastic; Animal Diseases; Animal Feed; Animal Husbandry; Animals; Central Nervous System Di

2011
Large BP-dependent and -independent differences in susceptibility to nephropathy after nitric oxide inhibition in Sprague-Dawley rats from two major suppliers.
    American journal of physiology. Renal physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Animals; Blood Pressure; Hypertension; Kidney Diseases; Kidney Glomerulus; Male; Nephrectomy; NG-Nit

2012
A blueberry-enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Antioxidants; Blueberry Plants; Body Weight; Catalase; Creatinine; Diet; Glutathione; Horme

2011
Amelioration of renal injury and oxidative stress by the nNOS inhibitor L-VNIO in the salt-sensitive mRen2.Lewis congenic rat.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:6

    Topics: Animals; Biopterins; Blood Pressure; Female; Gene Expression Regulation; Hypertension; Inflammation;

2012
Cysteinyl leukotriene receptor antagonism alleviates renal injury induced by ischemia-reperfusion in rats.
    The Journal of surgical research, 2012, Volume: 178, Issue:1

    Topics: Animals; Disease Models, Animal; Indoles; Intercellular Adhesion Molecule-1; Kidney Diseases; Leukot

2012
A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol.
    Nephron. Physiology, 2003, Volume: 93, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cyclic GMP; Enzyme Inhibitors; Hypertension; Kidney; Kidney Di

2003
RENAL TESTS IN TOXICITY STUDIES ON RATS.
    Toxicology and applied pharmacology, 1963, Volume: 5

    Topics: Aspartate Aminotransferases; Chromates; Kidney; Kidney Diseases; Mercury Poisoning; Nitrates; Nucleo

1963
[ON THE FORMATION AND ULTRASTRUCTURE OF "REGENERATION CELLS" IN THE RENAL TUBULES OF MICE POISONED BY URANYL NITRATE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Volume: 157

    Topics: Animals; Histology; Kidney Diseases; Kidney Tubules; Mice; Nitrates; Pharmacology; Regeneration; Res

1963
[ON ULTRASTRUCTURAL CHANGES OBSERVED IN THE RENAL TUBULES OF MICE TREATED WITH URANYL NITRATE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Volume: 157

    Topics: Animals; Kidney Diseases; Kidney Tubules; Mice; Nitrates; Pathology; Research; Toxicology; Uranium;

1963
Factors involved in the development of hypertension induced by a low-protein diet in rats with renal injury.
    Kidney & blood pressure research, 2004, Volume: 27, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Diet, Protein-Restricted; Dietary Supplements; Hype

2004
Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:5

    Topics: Actins; Administration, Inhalation; Animals; Apoptosis; Blotting, Western; Carbon Monoxide; Carboxyh

2004
Vasopeptidase inhibitor restores the balance of vasoactive hormones in progressive nephropathy.
    Kidney international, 2004, Volume: 66, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cyclic G

2004
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:2

    Topics: Acetophenones; Alanine Transaminase; Animals; Creatinine; DNA; Enzyme Inhibitors; Humans; Intestinal

2005
Time course study of oxidative and nitrosative stress and antioxidant enzymes in K2Cr2O7-induced nephrotoxicity.
    BMC nephrology, 2005, Apr-26, Volume: 6

    Topics: Acetylglucosaminidase; Animals; Catalase; Chromium; Creatine; Glutathione Peroxidase; Immunohistoche

2005
Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Blood Urea Nitrogen; Blotting, Western; Capillaries; Creatinine; Epithelial Cells; Immunohi

2007
Effect of renal injury-induced neurogenic hypertension on NO synthase, caveolin-1, AKt, calmodulin and soluble guanylate cyclase expressions in the kidney.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Pressure; Body Weight; Calmodulin; Caveolin 1; C

2007
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, May-01, Volume: 104, Issue:18

    Topics: Animals; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitrites; Receptor, Br

2007
Isohumulones derived from hops ameliorate renal injury via an anti-oxidative effect in Dahl salt-sensitive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:2

    Topics: Animals; Antioxidants; Blood Pressure; Blotting, Western; Cyclopentanes; Humulus; Hypertension; Kidn

2007
Serum nitric oxide metabolite (NO(x)) levels in hypertensive patients at rest: a comparison of age, gender, blood pressure and complications using normotensive controls.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:8

    Topics: Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers; Blood Pressure; Ca

2007
Protective effect of lipoic acid on oxidative and peroxidative damage in cyclosporine A-induced renal toxicity.
    International immunopharmacology, 2007, Volume: 7, Issue:11

    Topics: Albinism; Animals; Antioxidants; Cyclosporine; Gene Expression Regulation, Enzymologic; Kidney Disea

2007
Combining cisplatin with cationized catalase decreases nephrotoxicity while improving antitumor activity.
    Kidney international, 2007, Volume: 72, Issue:12

    Topics: Animals; Animals, Outbred Strains; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Catalas

2007
Reversal of cisplatin-induced carnitine deficiency and energy starvation by propionyl-L-carnitine in rat kidney tissues.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Blood Urea Nitrogen;

2007
Human umbilical cord blood-derived CD34+ cells can be used as a prophylactic agent for experimental heatstroke.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Animals; Antigens, CD34; Basal Ganglia; Cerebrovascular Disorders; Cord Blood Stem Cell Transplantat

2008
[Morphological manifestations of the toxic effect of uni- and bivalent mercury compounds during repeated peroral administration].
    Vrachebnoe delo, 1983, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Kidney; Kidney Diseases; Liver; Mercuric Chloride;

1983
L-arginine-nitric oxide pathway and chronic nephropathy in aged rats.
    Journal of gerontology, 1994, Volume: 49, Issue:4

    Topics: Aging; Amino Acids; Animals; Arginine; Blood Urea Nitrogen; Chronic Disease; Creatinine; Dietary Pro

1994
L-Arginine and allopurinol protect against cyclosporine nephrotoxicity.
    Transplantation, 1997, Apr-27, Volume: 63, Issue:8

    Topics: Allopurinol; Animals; Arginine; Cyclosporine; Enzyme Inhibitors; Glomerular Filtration Rate; Inulin;

1997
Protective role of metallothionein in renal toxicity of cisplatinum.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:4

    Topics: Animals; Antineoplastic Agents; Bismuth; Blood Urea Nitrogen; Cisplatin; Creatinine; Female; Injecti

1997
Increased mortality, blunted production of nitric oxide, and increased production of TNF-alpha in endotoxemic TGF-beta1 transgenic mice.
    Journal of leukocyte biology, 1998, Volume: 63, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Adhesion; Edema; Endotoxemia; Gene

1998
Analysis of urinary nitric oxide metabolites in healthy subjects.
    Endocrine journal, 1999, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arthritis, Rheumatoid; Chromatography, High Press

1999
Glomerular basement membrane anionic sites in adriamycin nephropathy: effect of saline loading and nitric oxide modulation.
    Nephron, 2000, Volume: 84, Issue:4

    Topics: Animals; Anions; Arginine; Basement Membrane; Binding Sites; Doxorubicin; Enzyme Inhibitors; Female;

2000
Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys.
    Kidney international, 2000, Volume: 58, Issue:1

    Topics: Alanine Transaminase; Anemia, Sickle Cell; Animals; Apoptosis; Aspartate Aminotransferases; Blotting

2000
Inverse regulation of endothelin-1 and nitric oxide metabolites in tissue with aging: implications for the age-dependent increase of cardiorenal disease.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1

    Topics: Aging; Animals; Endothelin-1; Female; Heart Diseases; Kidney Diseases; Male; Mice; Mice, Inbred C57B

2000
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide?
    Kidney & blood pressure research, 2001, Volume: 24, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Blood Pressure; Cyclosporine; Dinoproston

2001
Effect of trapidil, an antiplatelet and vasodilator agent on gentamicin-induced nephrotoxicity in rats.
    Pharmacological research, 2001, Volume: 44, Issue:4

    Topics: Animals; Creatinine; Dose-Response Relationship, Drug; Female; Gentamicins; Kidney; Kidney Diseases;

2001
Reciprocal regulation of cyclic GMP content by cyclic GMP-phosphodiesterase and guanylate cyclase in SHR with CsA-induced nephrotoxicity.
    British journal of pharmacology, 2001, Volume: 134, Issue:5

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Body Weight; Cyclic GMP; Cyclosporine; Dose-Response R

2001
Melatonin prevents cyclosporine-induced nephrotoxicity in isolated and perfused rat kidney.
    Free radical research, 2002, Volume: 36, Issue:3

    Topics: Animals; Antioxidants; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; K

2002
Kinetics of gallium nitrate, a new anticancer agent.
    Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Female; Gallium; Half-Life; Humans; Kidney Diseases; Kinetics; M

1979
Urinary findings (sediments and albumin) with respect to histopathologic alterations in uranyl nitrate chronic poisoning.
    Nauchni trudove na Visshiia meditsinski institut, Sofiia, 1966, Volume: 45, Issue:3

    Topics: Albuminuria; Animals; Hematuria; Kidney Diseases; Male; Nitrates; Rats; Uranium

1966
Pharmacologic and toxicologic studies with the polymyxins. 3. Consideration regarding clinical use in dogs.
    Chemotherapy, 1973, Volume: 19, Issue:2

    Topics: Aminohippuric Acids; Animals; Colistin; Dogs; Glomerular Filtration Rate; Glucose; Inulin; Kidney; K

1973
Alkaline phosphatase histochemistry and early renal cortical damage.
    The Histochemical journal, 1974, Volume: 6, Issue:2

    Topics: Alkaline Phosphatase; Animals; Ethylenes; Female; Glycols; Histocytochemistry; Kidney Cortex; Kidney

1974
[Determination of the concentration of amino-nitrates as a supplementary analysis in the examination of kidney function].
    Medicinski pregled, 1971, Volume: 24, Issue:8

    Topics: Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Nitrates; Renal Tubular Transport, I

1971
Identification of cells exfoliated from the rat kidney in experimental nephrotoxicity.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:1

    Topics: Animals; Cell Count; Chromates; Epithelium; Histocytochemistry; Kidney Diseases; Kidney Tubules; Neo

1970