Page last updated: 2024-10-19

nitrates and Ischemic Attack, Transient

nitrates has been researched along with Ischemic Attack, Transient in 23 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
" When combined at a dosage either positively or negatively skewed from each optimal dosage, however, co-treatment caused synergistic neuroprotection."1.37Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response. ( Chen, HY; Chen, TY; Huang, SY; Hung, YC; Lee, AC; Lee, EJ; Lee, MY; Shen, CC; Tai, SH; Wu, TS, 2011)
"Agmatine is a primary amine formed by the decarboxylation of L-arginine synthesized in mammalian brain."1.32Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury. ( Cho, SW; Giffard, RG; Kim, JH; Lee, JE; Park, KA; Yenari, MA, 2004)
"Tamoxifen has several potential mechanisms of action including inhibition of the release of excitatory amino acids (EAA) and nitric oxide synthase (NOS) activity."1.31Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat. ( Feustel, PJ; Kimelberg, HK; Mongin, AA; Osuka, K; Tranmer, BI, 2001)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (39.13)18.2507
2000's8 (34.78)29.6817
2010's5 (21.74)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Fan, JL1
O'Donnell, T1
Lanford, J1
Croft, K1
Watson, E1
Smyth, D1
Koch, H1
Wong, LK1
Tzeng, YC1
Kuzenkov, VS1
Zhang, C1
Zhang, Z1
Zhao, Q1
Wang, X1
Ji, H1
Zhang, Y1
Lee, EJ2
Chen, HY2
Hung, YC2
Chen, TY2
Lee, MY2
Yu, SC1
Chen, YH1
Chuang, IC1
Wu, TS2
Samson, ML1
Kajitani, K1
Robertson, GS1
Yuan, Z1
Liu, W1
Liu, B1
Schnell, A1
Liu, KJ1
Tai, SH1
Lee, AC1
Shen, CC1
Huang, SY1
Ohtaki, H1
Takaki, A1
Yin, L1
Dohi, K1
Nakamachi, T1
Matsunaga, M1
Horai, R1
Asano, M1
Iwakura, Y1
Shioda, S1
Zhang, DL1
Zhang, YT1
Yin, JJ1
Zhao, BL1
Kim, JH1
Yenari, MA1
Giffard, RG1
Cho, SW1
Park, KA1
Lee, JE1
Al-Majed, AA1
Sayed-Ahmed, MM1
Al-Omar, FA1
Al-Yahya, AA1
Aleisa, AM1
Al-Shabanah, OA1
Kumura, E1
Yoshimine, T1
Iwatsuki, KI1
Yamanaka, K1
Tanaka, S1
Hayakawa, T1
Shiga, T1
Kosaka, H1
Eliasson, MJ2
Sampei, K1
Mandir, AS1
Hurn, PD1
Traystman, RJ1
Bao, J1
Pieper, A1
Wang, ZQ1
Dawson, TM1
Snyder, SH2
Dawson, VL1
Grandati, M1
Verrecchia, C1
Revaud, ML1
Allix, M1
Boulu, RG1
Plotkine, M2
Fukuyama, N2
Takizawa, S2
Ishida, H1
Hoshiai, K1
Shinohara, Y2
Nakazawa, H2
Rizzo, V1
Montalbetti, L1
Rozza, AL1
Bolzani, W1
Porta, C1
Balduzzi, G1
Scoglio, E1
Moratti, R1
Coeroli, L1
Renolleau, S1
Arnaud, S1
Plotkine, D1
Cachin, N1
Ben-Ari, Y1
Charriaut-Marlangue, C1
Rao, AM1
Dogan, A1
Hatcher, JF1
Dempsey, RJ1
Hayashi, N1
Utagawa, A1
Kinoshita, K1
Izumi, T1
Huang, Z1
Ferrante, RJ1
Sasamata, M1
Molliver, ME1
Moskowitz, MA1
Hirabayashi, H1
Calapai, G1
Crupi, A1
Firenzuoli, F1
Marciano, MC1
Squadrito, F1
Inferrera, G1
Parisi, A1
Rizzo, A1
Crisafulli, C1
Fiore, A1
Caputi, AP1
Osuka, K1
Feustel, PJ1
Mongin, AA1
Tranmer, BI1
Kimelberg, HK1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Production of Fortified Biscuit With Chickpea and Crushed Peanut and Evaluating Its Effectiveness in Terms of Its Acceptability and Cognitive Performance: a Pilot Study Among Egyptian Primary School-aged Children[NCT05281146]80 participants (Actual)Interventional2018-11-26Completed
Shuxuening Injection for the Prevention of Cerebral Vasospasm in Patients With Aneurysmal Subarachnoid Hemorrhage -- A Randomized, Double-blind, Placebo-parallel Controlled Clinical Trial[NCT06138353]Phase 2/Phase 350 participants (Anticipated)Interventional2023-11-13Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for nitrates and Ischemic Attack, Transient

ArticleYear
Dietary nitrate reduces blood pressure and cerebral artery velocity fluctuations and improves cerebral autoregulation in transient ischemic attack patients.
    Journal of applied physiology (Bethesda, Md. : 1985), 2020, 09-01, Volume: 129, Issue:3

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Homeostas

2020

Other Studies

22 other studies available for nitrates and Ischemic Attack, Transient

ArticleYear
Protective Role of Nitrate/Nitrite Reductase System during Transient Global Cerebral Ischemia.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:1

    Topics: Animals; Brain Ischemia; Ischemic Attack, Transient; Male; Nitrate Reductase; Nitrates; Nitric Oxide

2018
(S)-ZJM-289 preconditioning induces a late phase protection against nervous injury induced by transient cerebral ischemia and oxygen-glucose deprivation.
    Neurotoxicity research, 2014, Volume: 26, Issue:1

    Topics: Animals; Apoptosis; Brain; Cells, Cultured; Cinnamates; Flavonoids; Glucose; Hypoxia-Ischemia, Brain

2014
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
    Experimental neurology, 2009, Volume: 217, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Lin

2009
Nitric-oxide synthase mediates the ability of darbepoetin alfa to attenuate pre-existing spatial working memory deficits in rats subjected to transient global ischemia.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:2

    Topics: Animals; CA1 Region, Hippocampal; Darbepoetin alfa; Erythropoietin; Hippocampus; Ischemic Attack, Tr

2010
Normobaric hyperoxia delays and attenuates early nitric oxide production in focal cerebral ischemic rats.
    Brain research, 2010, Sep-17, Volume: 1352

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Hyperoxia; Ischemic Attack, Transient; Male; Middle Ce

2010
Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response.
    Journal of pineal research, 2011, Volume: 50, Issue:3

    Topics: Animals; Animals, Newborn; Body Weight; Cell Line; Cells, Cultured; Estrogens; Female; Interleukin-6

2011
Suppression of oxidative stress after transient focal ischemia in interleukin-1 knock out mice.
    Acta neurochirurgica. Supplement, 2003, Volume: 86

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Brain; Cattle; Deoxyguanosine; Infarction, Middle Cerebral Art

2003
Oral administration of Crataegus flavonoids protects against ischemia/reperfusion brain damage in gerbils.
    Journal of neurochemistry, 2004, Volume: 90, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Brain Chemistry; Cell Nucleus; Crataegus; Disease Model

2004
Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: Agmatine; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Brain Infarction; Cell

2004
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:8

    Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Disease Models, Animal; Energy Metaboli

2006
Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Animals; Arginine; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hemoglobins; Ischemic At

1996
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
    Nature medicine, 1997, Volume: 3, Issue:10

    Topics: Adenosine Triphosphate; Animals; Benzamides; Brain; Cells, Cultured; Cerebral Cortex; Cerebrovascula

1997
Calcium-independent NO-synthase activity and nitrites/nitrates production in transient focal cerebral ischaemia in mice.
    British journal of pharmacology, 1997, Volume: 122, Issue:4

    Topics: Animals; Calcium; Hydrolysis; Ischemic Attack, Transient; Male; Mice; Nitrates; Nitric Oxide Synthas

1997
Peroxynitrite formation in focal cerebral ischemia-reperfusion in rats occurs predominantly in the peri-infarct region.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1998, Volume: 18, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Ischemic Attack, Transient; Male; Nitrates; Rats; Rat

1998
Nitrite/nitrate balance during photoinduced cerebral ischemia in the rat determined by high-performance liquid chromatography with UV and electrochemical detection.
    Journal of chromatography. A, 1998, Mar-06, Volume: 798, Issue:1-2

    Topics: Animals; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Ischemic Attack, Transien

1998
Nitric oxide production and perivascular tyrosine nitration following focal ischemia in neonatal rat.
    Journal of neurochemistry, 1998, Volume: 70, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Cell Death; Female; Immunoenzyme Techniques; Ischemic Attack, Tran

1998
Fluorometric assay of nitrite and nitrate in brain tissue after traumatic brain injury and cerebral ischemia.
    Brain research, 1998, May-18, Volume: 793, Issue:1-2

    Topics: 2-Naphthylamine; 4-Hydroxycoumarins; Animals; Brain Chemistry; Brain Injuries; Gerbillinae; Ischemic

1998
Application of a novel technique for clinical evaluation of nitric oxide-induced free radical reactions in ICU patients.
    Cellular and molecular neurobiology, 1999, Volume: 19, Issue:1

    Topics: Adult; Brain; Critical Care; Female; Free Radicals; Humans; Hypothermia, Induced; Ischemic Attack, T

1999
Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-15, Volume: 19, Issue:14

    Topics: Animals; Brain; Cerebral Infarction; Citrulline; Corpus Striatum; Enzyme Activation; Functional Late

1999
Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion.
    Brain research, 2000, Jan-10, Volume: 852, Issue:2

    Topics: Acidosis; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Cerebrovascular C

2000
Neuroprotective effects of Ginkgo biloba extract in brain ischemia are mediated by inhibition of nitric oxide synthesis.
    Life sciences, 2000, Oct-20, Volume: 67, Issue:22

    Topics: Administration, Oral; Animals; Brain; Brain Edema; Cell Death; Dose-Response Relationship, Drug; Ger

2000
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.
    Journal of neurochemistry, 2001, Volume: 76, Issue:6

    Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Ischemic Atta

2001