Page last updated: 2024-10-19

nitrates and Ischemia

nitrates has been researched along with Ischemia in 80 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Since blood flow is mediated, in part, by nitric oxide (NO), we hypothesized that sodium nitrate provided before forearm grip exercise performed at a simulated altitude of 4300 m (hypobaric hypoxia (HH)) would increase forearm blood flow and oxygenation, and decrease the decrement in grip performance."7.85Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m). ( Fothergill, DM; Gasier, HG; Loiselle, AR; Reinhold, AR; Soutiere, SE, 2017)
" During limb ischemia, decreased NO bioavailability occurs secondary to increased oxidant stress, decreased L-arginine and tetrahydrobiopterin."7.78Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat. ( Messina, LM; Tie, G; Yan, J, 2012)
"The effect of nitroglycerine on some parameters of the prooxidant-antioxidant balance and functional state of the liver under conditions of ischemia/reperfusion was studied on rabbits."7.73Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion. ( Khodosovskii, MN; Zinchuk, VV, 2006)
"Decreased renal arginine production is observed with unilateral ischemia-reperfusion, and this change in arginine flux could contribute to or slow the recovery from the low plasma levels of arginine seen in conditions like trauma, shock, or after vascular procedures."7.71The flux of arginine after ischemia-reperfusion in the rat kidney. ( Gasselt, DV; Nijveldt, RJ; Prins, HA; Rauwerda, JA; Teerlink, T; van Kemenade, F; van Lambalgen, AA; van Leeuwen, PA, 2002)
"Preischemia or prereperfusion administration of trapidil (8 mg/kg) was evaluated in the rat sciatic nerve I/R injury model."7.71Effect of trapidil in ischemia/reperfusion injury of peripheral nerves. ( Bagdatoglu, C; Ozturk, H; Saray, A; Surucu, HS; Tamer, L, 2002)
"Hyperhomocysteinemia (HH) is an independent risk factor for atherosclerosis, including peripheral arterial occlusive disease (PAOD)."7.70Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. ( Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S, 2000)
"We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy."7.67Nifedipine-induced hypotension and mesenteric ischemia. ( Deppe, SA; Elliott, BM; Goglin, WK, 1989)
"Ischemia was followed by a significant increase in muscle myeloperoxidase activity, as well as interleukin-6 and thiobarbituric acid reactive substances species levels."5.48N-acetylcysteine effects on a murine model of chronic critical limb ischemia. ( Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F, 2018)
" Further studies evaluating longer-duration nitrite therapy and/or additional nitrite dosing strategies are warranted to more fully evaluate the therapeutic potential of nitrite therapy in peripheral vascular disease."5.42Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome. ( Bradley, JM; Brewster, LP; Calvert, JW; Chang, CC; Goodchild, TT; Islam, KN; Lefer, DJ; Pipinos, II; Polhemus, DJ; Tao, YX, 2015)
"To examine the antioxidant role of propofol in ischemia-reperfusion during carotid endarterectomy (CEA) and its influence on cognitive dysfunction after CEA."5.17Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia. ( Fragopoulou, E; Kakisis, J; Kalimeris, K; Kostopanagiotou, G; Kouni, S; Matsota, P; Nomikos, T; Pandazi, A; Vasdekis, S, 2013)
" Since blood flow is mediated, in part, by nitric oxide (NO), we hypothesized that sodium nitrate provided before forearm grip exercise performed at a simulated altitude of 4300 m (hypobaric hypoxia (HH)) would increase forearm blood flow and oxygenation, and decrease the decrement in grip performance."3.85Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m). ( Fothergill, DM; Gasier, HG; Loiselle, AR; Reinhold, AR; Soutiere, SE, 2017)
" Treatment with ixmyelocel-T in a rat model of hind limb ischemia resulted in significantly increased blood flow perfusion and capillary density, gene expression and plasma levels of the anti-inflammatory cytokine interleukin (IL)-10, plasma nitrates, plasma platelet-derived growth factor (PDGF)-BB, vascular endothelial growth factor (VEGF) expression, and significantly decreased plasma thiobarbituric acid reactive substances (TBARS)."3.81Therapeutic potential of ixmyelocel-T, an expanded autologous multicellular therapy for treatment of ischemic cardiovascular diseases. ( Bartel, RL; Ledford, KJ; Murphy, N; Tubo, R; Zeigler, F, 2015)
" During limb ischemia, decreased NO bioavailability occurs secondary to increased oxidant stress, decreased L-arginine and tetrahydrobiopterin."3.78Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat. ( Messina, LM; Tie, G; Yan, J, 2012)
"The effect of nitroglycerine on some parameters of the prooxidant-antioxidant balance and functional state of the liver under conditions of ischemia/reperfusion was studied on rabbits."3.73Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion. ( Khodosovskii, MN; Zinchuk, VV, 2006)
" ONO-1714 significantly attenuated apoptosis and necrosis, the expression of nitrotyrosine, and the increases of the plasma aspartate aminotransferase, lactate dehydrogenase, and NO(2)- + NO(3)- levels in the reperfusion phase."3.72Apoptosis and necrosis after warm ischemia-reperfusion injury of the pig liver and their inhibition by ONO-1714. ( Hirata, K; Isobe, M; Katsuramaki, T; Kimura, H; Kukita, K; Meguro, M; Nagayama, M; Nui, A, 2003)
"Preischemia or prereperfusion administration of trapidil (8 mg/kg) was evaluated in the rat sciatic nerve I/R injury model."3.71Effect of trapidil in ischemia/reperfusion injury of peripheral nerves. ( Bagdatoglu, C; Ozturk, H; Saray, A; Surucu, HS; Tamer, L, 2002)
" To determine the level of NO in the cochlea after 20 to 120 min of ischemia, nitrites/nitrates in the perilymph were measured."3.71Effects of nitric oxide on normal and ischemic cochlea of the guinea pig. ( Leong, SK; Ruan, RS; Yeoh, KH, 2001)
"Decreased renal arginine production is observed with unilateral ischemia-reperfusion, and this change in arginine flux could contribute to or slow the recovery from the low plasma levels of arginine seen in conditions like trauma, shock, or after vascular procedures."3.71The flux of arginine after ischemia-reperfusion in the rat kidney. ( Gasselt, DV; Nijveldt, RJ; Prins, HA; Rauwerda, JA; Teerlink, T; van Kemenade, F; van Lambalgen, AA; van Leeuwen, PA, 2002)
" We examined the hypothesis that HC may inhibit ischemia-induced angiogenesis by inhibition of EDNO in a rat model of unilateral hindlimb ischemia and that oral L-arginine supplementation, a substrate for NO synthase, may prevent HC-related impairment of angiogenesis."3.70Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. ( Duan, J; Ikeda, H; Imaizumi, T; Katoh, A; Kawata, H; Murohara, T; Sasaki, K; Shintani, S; Yamamoto, N, 2000)
"Hyperhomocysteinemia (HH) is an independent risk factor for atherosclerosis, including peripheral arterial occlusive disease (PAOD)."3.70Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. ( Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S, 2000)
" Nitrates clearly express the injury to the organs caused by warm ischemia-reperfusion."3.69[Role of nitric oxide in warm ischemia of the transplanted kidney]. ( Antolín Juárez, F; Correas Gómez, MA; de Diego Rodríguez, JE; del Valle Schaan, JI; Gutiérrez Baños, JL; Gutiérrez García, R; Hernández Rodríguez, R; Martín García, B; Portillo Martín, JA; Roca Edreira, A; Vega Vega, A; Villanueva Peña, A, 1997)
"We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy."3.67Nifedipine-induced hypotension and mesenteric ischemia. ( Deppe, SA; Elliott, BM; Goglin, WK, 1989)
"Ischemia was followed by a significant increase in muscle myeloperoxidase activity, as well as interleukin-6 and thiobarbituric acid reactive substances species levels."1.48N-acetylcysteine effects on a murine model of chronic critical limb ischemia. ( Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F, 2018)
" Further studies evaluating longer-duration nitrite therapy and/or additional nitrite dosing strategies are warranted to more fully evaluate the therapeutic potential of nitrite therapy in peripheral vascular disease."1.42Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome. ( Bradley, JM; Brewster, LP; Calvert, JW; Chang, CC; Goodchild, TT; Islam, KN; Lefer, DJ; Pipinos, II; Polhemus, DJ; Tao, YX, 2015)
" Nitrite significantly increased ischemic tissue NO bioavailability along with concomitant reduction of superoxide formation."1.40Nitrite anion therapy protects against chronic ischemic tissue injury in db/db diabetic mice in a NO/VEGF-dependent manner. ( Bir, SC; Giordano, T; Kevil, CG; Kolluru, GK; Pardue, S; Pattillo, CB; Shen, X, 2014)
"The delaying effects of remote reperfusion injury on the wound-healing process in colonic anastomoses have been previously shown."1.35Activated protein C prevents deleterious effects of remote reperfusion injury caused by intestinal ischemia on wound healing in the left colonic anastomoses: an experimental study in the murine model. ( Atalay, AO; Bicakci, T; Erdem, E; Sacar, M; Teke, Z; Yenisey, C, 2008)
" Control mice received an equimolar dosage of the parent statin compound, pravastatin."1.34Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice. ( Campesi, I; Emanueli, C; Gadau, S; Kraenkel, N; Madeddu, P; Meloni, M; Monopoli, A; Ongini, E, 2007)
"Whereas ischemia is often considered to be synonymous with an oxygen deficit, it is also associated with a concomitant local elevation of carbon dioxide (CO2)."1.33Hypercapnia prevents neovascularization via nitrative stress. ( Balazy, M; Brault, S; Checchin, D; Chemtob, S; Hardy, P; Kermorvant-Duchemin, E; Sennlaub, F; Sirinyan, M; Zhu, T, 2006)
"Lower-limb ischemia is a major health problem."1.33Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb. ( Botti, C; Byrns, RE; de Nigris, F; de Rosa, G; Farzati, B; Fiore, A; Ignarro, LJ; Lerman, LO; Matarazzo, A; Napoli, C; Sica, G; Sica, V; Sumi, D; Williams-Ignarro, S, 2005)
"The mechanism of gut injury in endotoxic shock seems unrelated to hypoxia and release of nitric oxide."1.32Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia. ( De Backer, D; Dimopoulos, G; Lobo, SM; Nagy, N; Preiser, JC; Sun, Q; Terzi, RG; Tu, Z; Vercruy, V; Vincent, JL; Vray, B, 2003)
"Ischemia-reperfusion injury was induced in the rat stomach."1.30Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats. ( Arai, M; Kaneko, T; Kondo, M; Matsuyama, K; Naito, Y; Nakamura, Y; Yagi, N; Yoshida, N; Yoshikawa, T, 1998)
"SAO shock was induced by clamping both the superior mesenteric artery and the celiac trunk, followed by release of the clamp."1.30IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock. ( Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Mazzon, E, 1999)
"The rats with diabetic acute renal failure had a much lower creatinine clearance (90 +/- 22 microliters."1.29Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats. ( Blum, M; Cabili, S; Chernihovsky, T; Goor, Y; Iaina, A; Peer, G; Silverberg, D; Wollman, Y, 1996)
"After treatment of ischemia and/or failure, specific antiarrhythmic agents, conventional and investigational, alone or in combination, are systematically selected."1.26Ventricular ectopy: etiology, evaluation, and therapy. ( Reid, PR; Vlay, SC, 1982)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19907 (8.75)18.7374
1990's19 (23.75)18.2507
2000's33 (41.25)29.6817
2010's17 (21.25)24.3611
2020's4 (5.00)2.80

Authors

AuthorsStudies
Olejnik, A1
Banaszkiewicz, M1
Krzywonos-Zawadzka, A1
Bil-Lula, I1
Meng, Z1
Gai, W1
Song, D1
Travis, OK1
Baik, C1
Tardo, GA1
Amaral, L1
Jackson, C1
Greer, M1
Giachelli, C1
Ibrahim, T1
Herrock, OT1
Williams, JM1
Cornelius, DC1
Zhang, G1
Han, H1
Zhuge, Z1
Dong, F1
Jiang, S1
Wang, W1
Guimarães, DD1
Schiffer, TA1
Lai, EY1
Ribeiro Antonino Carvalho, LR1
Lucena, RB1
Braga, VA1
Weitzberg, E2
Lundberg, JO2
Carlstrom, M1
Kolb, L1
Orbegozo, D1
Creteur, J1
Preiser, JC2
Vincent, JL2
De Backer, D2
Gasier, HG1
Reinhold, AR1
Loiselle, AR1
Soutiere, SE1
Fothergill, DM1
de Medeiros, WA1
da Silva, LA1
Dall'Igna, DM1
Michels, M1
Manfredini, A1
Dos Santos Cardoso, J1
Constantino, L1
Scaini, G1
Vuolo, F1
Streck, EL1
Ritter, C1
Dal-Pizzol, F1
Sertorio, JT1
Tanus-Santos, JE1
Cui, H1
Wang, Y2
Feng, Y1
Li, X1
Bu, L1
Pang, B1
Jia, M1
Iltar, S1
Kılınç, CY1
Alemdaroğlu, KB1
Ozcan, S1
Aydoğan, NH1
Sürer, H1
Kılınç, AŞ1
Kalimeris, K1
Kouni, S1
Kostopanagiotou, G1
Nomikos, T1
Fragopoulou, E1
Kakisis, J1
Vasdekis, S1
Matsota, P1
Pandazi, A1
Bir, SC1
Pattillo, CB1
Pardue, S1
Kolluru, GK2
Shen, X1
Giordano, T1
Kevil, CG2
Lo, HC1
Yang, RB1
Lee, CH1
Yasmeen, G1
Dawani, ML1
Mahboob, T1
Ledford, KJ1
Murphy, N1
Zeigler, F1
Bartel, RL1
Tubo, R1
Polhemus, DJ1
Bradley, JM1
Islam, KN1
Brewster, LP1
Calvert, JW1
Tao, YX1
Chang, CC1
Pipinos, II1
Goodchild, TT1
Lefer, DJ1
Nelson, MD1
Rosenberry, R1
Barresi, R1
Tsimerinov, EI1
Rader, F1
Tang, X1
Mason, O1
Schwartz, A1
Stabler, T1
Shidban, S1
Mobaligh, N1
Hogan, S1
Elashoff, R1
Allen, JD1
Victor, RG1
Feelisch, M1
Fernandez, BO1
Bryan, NS1
Garcia-Saura, MF1
Bauer, S1
Whitlock, DR1
Ford, PC1
Janero, DR1
Rodriguez, J1
Ashrafian, H1
Raat, NJ1
Noguchi, AC1
Liu, VB1
Raghavachari, N1
Liu, D1
Xu, X1
Shiva, S1
Munson, PJ1
Gladwin, MT1
Tao, RR1
Huang, JY1
Shao, XJ1
Ye, WF1
Tian, Y1
Liao, MH1
Fukunaga, K1
Lou, YJ1
Han, F1
Lu, YM1
Hendgen-Cotta, UB1
Luedike, P1
Totzeck, M1
Kropp, M1
Schicho, A1
Stock, P1
Rammos, C1
Niessen, M1
Heiss, C1
Kelm, M1
Rassaf, T1
Yan, J1
Tie, G1
Messina, LM1
Bagdatoglu, C1
Saray, A1
Surucu, HS1
Ozturk, H1
Tamer, L1
Meguro, M2
Katsuramaki, T2
Kimura, H2
Isobe, M2
Nagayama, M2
Kukita, K1
Nui, A2
Hirata, K2
Lobo, SM1
Sun, Q1
Tu, Z2
Dimopoulos, G1
Nagy, N1
Vray, B1
Vercruy, V1
Terzi, RG1
Shimada, T2
Takeshita, Y1
Murohara, T3
Sasaki, K3
Egami, K1
Shintani, S3
Katsuda, Y1
Ikeda, H3
Nabeshima, Y1
Imaizumi, T3
Jacobi, J1
Sydow, K1
von Degenfeld, G1
Zhang, Y1
Dayoub, H1
Wang, B1
Patterson, AJ1
Kimoto, M1
Blau, HM1
Cooke, JP1
Meadows, GE1
Kotajima, F1
Vazir, A1
Kostikas, K1
Simonds, AK1
Morrell, MJ1
Corfield, DR1
Napoli, C1
Williams-Ignarro, S1
de Nigris, F1
de Rosa, G1
Lerman, LO1
Farzati, B1
Matarazzo, A1
Sica, G1
Botti, C1
Fiore, A1
Byrns, RE1
Sumi, D1
Sica, V1
Ignarro, LJ1
Checchin, D1
Sennlaub, F1
Sirinyan, M1
Brault, S1
Zhu, T1
Kermorvant-Duchemin, E1
Hardy, P2
Balazy, M1
Chemtob, S2
Unno, N1
Uchiyama, T1
Yamamoto, N2
Inuzuka, K1
Sagara, D1
Konno, H1
Emanueli, C1
Monopoli, A1
Kraenkel, N1
Meloni, M1
Gadau, S1
Campesi, I1
Ongini, E1
Madeddu, P1
Stefanutti, G1
Pierro, A1
Smith, VV1
Klein, NJ1
Eaton, S1
Kim, HW1
Lin, A1
Guldberg, RE1
Ushio-Fukai, M1
Fukai, T1
Khodosovskii, MN1
Zinchuk, VV1
Joviliano, EE1
Piccinato, CE1
Cherri, J1
Viaro, F1
Moryia, T1
Celotto, AC1
Bonaventura, D1
Evora, PR1
Lauer, S1
Daudel, F1
Traber, DL2
Nofer, JR1
Ertmer, C1
Morelli, A1
Van Aken, H1
Lange, M1
Rehberg, S1
Ellger, B1
Stubbe, HD1
Kruse, C1
Bone, HG1
Westphal, M1
Teke, Z1
Sacar, M1
Yenisey, C1
Atalay, AO1
Bicakci, T1
Erdem, E1
Vlay, SC1
Reid, PR1
Grisham, MB1
Ischiropoulos, H1
al-Mehdi, AB1
Fisher, AB1
Esteban, F1
Gómez-Jiménez, J1
Martín, MC1
Ruíz, JC1
Nuvials, X1
García-Allut, JL1
Sauri, R1
Murio, JE1
Mourelle, M1
Segura, RM1
Benedini, F1
Bertolini, G1
Cereda, R1
Donà, G1
Gromo, G1
Levi, S1
Mizrahi, J1
Sala, A1
Beckman, JS1
Crow, JP1
Szabó, C3
Goor, Y1
Peer, G1
Iaina, A1
Blum, M1
Wollman, Y1
Chernihovsky, T1
Silverberg, D1
Cabili, S1
Correas Gómez, MA1
Martín García, B1
Antolín Juárez, F1
Hernández Rodríguez, R1
Portillo Martín, JA1
Gutiérrez Baños, JL1
del Valle Schaan, JI1
Roca Edreira, A1
Vega Vega, A1
Villanueva Peña, A1
Gutiérrez García, R1
de Diego Rodríguez, JE1
Millar, TM1
Stevens, CR1
Blake, DR1
Naito, Y1
Yoshikawa, T1
Matsuyama, K1
Yagi, N1
Arai, M1
Nakamura, Y1
Kaneko, T1
Yoshida, N1
Kondo, M1
Liu, P3
Yin, K1
Nagele, R2
Wong, PY3
Wada, K1
Kamisaki, Y1
Ohkura, T1
Kanda, G1
Nakamoto, K1
Kishimoto, Y1
Ashida, K1
Itoh, T1
Lawson, JA1
Jaeschke, H1
Endres, M1
Scott, GS1
Salzman, AL2
Kun, E1
Moskowitz, MA1
Xu, B2
Hock, CE1
Sun, FF1
Mazzone, A1
Cusa, C1
Bucci, L1
Vezzoli, M1
Ghio, S1
Buggia, I1
Regazzi, MB1
Fossati, G1
Mazzucchelli, I1
Gritti, D1
Lapane, KL1
Barbour, MM1
Van Haaren, A1
Gambassi, G1
Cuzzocrea, S1
De Sarro, G1
Costantino, G1
Ciliberto, G1
Mazzon, E1
De Sarro, A1
Caputi, AP1
Spokas, E1
Lai, PS1
Prior, DL1
Chin-Dusting, JP1
Liaudet, L1
Szabó, A1
Soriano, FG1
Zingarelli, B1
Huk, I1
Brovkovych, V1
Nanobashvili, J1
Neumayer, C1
Polterauer, P1
Prager, M1
Patton, S1
Malinski, T1
Dumont, I1
Bhattacharya, M1
Hou, X1
Lachapelle, P1
Varma, DR1
Walker, LM1
Walker, PD1
Imam, SZ1
Ali, SF1
Mayeux, PR1
Duan, J2
Katoh, A1
Kawata, H1
Akita, T1
Osanai, H1
Okumura, K1
Hayakawa, M1
Harada, M1
Numaguchi, Y1
Mokuno, S1
Murase, K1
Matsui, H1
Toki, Y1
Ito, T1
Hayakawa, T1
Ruan, RS1
Leong, SK1
Yeoh, KH1
Ogawa, T1
Nussler, AK1
Tuzuner, E1
Mimura, Y1
Kaminishi, M1
Beger, HG1
Tokuyama, H1
Hayashi, K1
Matsuda, H1
Kubota, E1
Honda, M1
Okubo, K1
Ozawa, Y1
Saruta, T1
Kimura, Y1
Matsuno, T1
Prins, HA1
Nijveldt, RJ1
Gasselt, DV1
van Kemenade, F1
Teerlink, T1
van Lambalgen, AA1
Rauwerda, JA1
van Leeuwen, PA1
Duprat, R1
Meneghelo, RS1
Batlouni, M1
Hoxter, G1
Wennmalm, A1
Lanne, B1
Petersson, AS1
Goglin, WK1
Elliott, BM1
Deppe, SA1
Flamenbaum, W1
Huddleston, ML1
McNeil, JS1
Hamburger, RJ1
Russek, HI1
Goldbarg, AN1
Moran, JF1
Butterfield, TK1
Nemickas, R1
Bermudez, GA1
Tapp, E1
Lowe, MB1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Protective Effect of Melatonin in Patients Under Carotid Endarterectomy[NCT03115034]Phase 460 participants (Actual)Interventional2016-06-01Completed
Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Incidence of Postoperative Delirium in Elderly Patients After Cancer Surgery: An Open-label, Randomized Controlled Trial[NCT02662257]1,228 participants (Actual)Interventional2015-04-01Completed
A Randomized, Double - Blind, Placebo - Controlled Trial to Investigate the Effect of Dapagliflozin on Ischemia Reperfusion Induced Endothelial Dysfunction of the Forearm Vasculature in Healthy Male Subjects[NCT05217654]Phase 132 participants (Anticipated)Interventional2022-02-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for nitrates and Ischemia

ArticleYear
Postconditioning with Nitrates Protects Against Myocardial Reperfusion Injury: A New Use for an Old Pharmacological Agent.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, Jun-09, Volume: 26

    Topics: Animals; Humans; Ischemia; Ischemic Postconditioning; Myocardial Infarction; Myocardial Reperfusion;

2020
Pathological implications of nitric oxide, superoxide and peroxynitrite formation.
    Biochemical Society transactions, 1993, Volume: 21, Issue:2

    Topics: Animals; Ischemia; Macrophages; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides

1993
The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.
    Shock (Augusta, Ga.), 1996, Volume: 6, Issue:2

    Topics: Animals; Humans; Hydroxyl Radical; Inflammation; Ischemia; Nitrates; Nitric Oxide; Nitric Oxide Synt

1996
Oxidants, nitric oxide and prostanoids in the developing ocular vasculature: a basis for ischemic retinopathy.
    Cardiovascular research, 2000, Aug-18, Volume: 47, Issue:3

    Topics: Choroid; Dinoprost; Endothelial Growth Factors; Free Radicals; Humans; Infant, Newborn; Infant, Prem

2000

Trials

7 trials available for nitrates and Ischemia

ArticleYear
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Cognitive function and oxidative stress after carotid endarterectomy: comparison of propofol to sevoflurane anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Association of high-density lipoprotein cholesterol with improvement of endothelial dysfunction recovery in renovascular disease.
    Iranian journal of kidney diseases, 2015, Volume: 9, Issue:1

    Topics: Adult; Atorvastatin; Biomarkers; Cholesterol, HDL; Delayed-Action Preparations; Drug Therapy, Combin

2015
Sodium nitrate alleviates functional muscle ischaemia in patients with Becker muscular dystrophy.
    The Journal of physiology, 2015, Dec-01, Volume: 593, Issue:23

    Topics: Administration, Oral; Adolescent; Adult; Humans; Ischemia; Male; Middle Aged; Muscle, Skeletal; Musc

2015
The effects of iloprost infusion on microcirculation is independent of nitric oxide metabolites and endothelin-1 in chronic peripheral ischaemia.
    European journal of clinical investigation, 1999, Volume: 29, Issue:1

    Topics: Adult; Aged; Arterial Occlusive Diseases; Chronic Disease; Endothelin-1; Endothelium, Vascular; Fema

1999
Transient improvement of acetylcholine responses after short-term oral L-arginine in forearms of human heart failure.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:1

    Topics: Acetylcholine; Administration, Oral; Adult; Analysis of Variance; Arginine; Blood Pressure; Cross-Ov

2000
New dimension in angina pectoris therapy.
    Geriatrics, 1969, Volume: 24, Issue:3

    Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Drug Synergism; Electrocar

1969
Therapy of angina pectoris with propranolol and long-acting nitrates.
    Circulation, 1969, Volume: 40, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Exercis

1969

Other Studies

69 other studies available for nitrates and Ischemia

ArticleYear
The Klotho protein supports redox balance and metabolic functions of cardiomyocytes during ischemia/reperfusion injury.
    Cardiology journal, 2022, Volume: 29, Issue:5

    Topics: Deoxyglucose; Glucose; Humans; Hydrogen Peroxide; Ischemia; Lactates; Myocytes, Cardiac; NADP; NADPH

2022
Adoptive transfer of placental ischemia-stimulated natural killer cells causes a preeclampsia-like phenotype in pregnant rats.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2021, Volume: 85, Issue:6

    Topics: Adoptive Transfer; Animals; Cyclic GMP; Cytokines; Female; Fetal Growth Retardation; Ischemia; Kille

2021
Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney.
    Redox biology, 2021, Volume: 39

    Topics: Animals; Endothelial Cells; Ischemia; Kidney; Male; Mice; Mice, Inbred C57BL; Nitrates; Oxidative St

2021
Oral Nitrate Increases Microvascular Reactivity and the Number of Visible Perfused Microvessels in Healthy Volunteers.
    Journal of vascular research, 2017, Volume: 54, Issue:4

    Topics: Administration, Oral; Adult; Biomarkers; Blood Flow Velocity; Diffusion; Female; Healthy Volunteers;

2017
Effects of oral sodium nitrate on forearm blood flow, oxygenation and exercise performance during acute exposure to hypobaric hypoxia (4300 m).
    Nitric oxide : biology and chemistry, 2017, Sep-30, Volume: 69

    Topics: Adult; Athletic Performance; Blood Pressure; Exercise; Female; Forearm; Heart Rate; Humans; Hypoxia;

2017
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:2

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alph

2018
Mechanisms involved in proton pump inhibitors-induced increases in ischemic events.
    Atherosclerosis, 2019, Volume: 280

    Topics: Humans; Ischemia; Nitrates; Nitrites; Proton Pump Inhibitors

2019
Dietary nitrate protects skin flap against ischemia injury in rats via enhancing blood perfusion.
    Biochemical and biophysical research communications, 2019, 07-12, Volume: 515, Issue:1

    Topics: Animals; Cytokines; Dermatologic Surgical Procedures; Diet; Inflammation Mediators; Ischemia; Male;

2019
Does the method of expression of venous blood affect ischaemia/reperfusion damage in tourniquet use? An experimental study on rabbits.
    Injury, 2013, Volume: 44, Issue:11

    Topics: Acidosis; Animals; Biomarkers; Ischemia; Malondialdehyde; Muscle, Skeletal; Nitrates; Nitrites; Orth

2013
Nitrite anion therapy protects against chronic ischemic tissue injury in db/db diabetic mice in a NO/VEGF-dependent manner.
    Diabetes, 2014, Volume: 63, Issue:1

    Topics: Animals; Diabetes Mellitus, Type 2; Femoral Artery; Hindlimb; Ischemia; Mice; Neovascularization, Pa

2014
Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Animals; Apoptosis; I-kappa B Proteins; Inflammation; Interleukin-6; Ischemia; Jejunum; JNK Mitogen-

2014
Therapeutic potential of ixmyelocel-T, an expanded autologous multicellular therapy for treatment of ischemic cardiovascular diseases.
    Stem cell research & therapy, 2015, Mar-13, Volume: 6

    Topics: Animals; Apoptosis; Becaplermin; Bone Marrow Cells; Bone Marrow Transplantation; Cell Proliferation;

2015
Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome.
    American journal of physiology. Heart and circulatory physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Angiogenesis Inducing Agents; Animals; Delayed-Action Preparations; Disease Models, Animal; Hindlimb

2015
Tissue processing of nitrite in hypoxia: an intricate interplay of nitric oxide-generating and -scavenging systems.
    The Journal of biological chemistry, 2008, Dec-05, Volume: 283, Issue:49

    Topics: Animals; Heme; Hypoxia; Iron-Sulfur Proteins; Ischemia; Liver; Male; Mitochondria; Models, Theoretic

2008
Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response.
    Free radical biology & medicine, 2009, Sep-01, Volume: 47, Issue:5

    Topics: Animal Structures; Animals; Cytoprotection; Diet; Gastric Mucosa; Gene Expression Profiling; Heart;

2009
Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin.
    Journal of pineal research, 2013, Volume: 54, Issue:3

    Topics: Analysis of Variance; Antioxidants; Cell Line; Endothelial Cells; Glucose; Histocytochemistry; Human

2013
Dietary nitrate supplementation improves revascularization in chronic ischemia.
    Circulation, 2012, Oct-16, Volume: 126, Issue:16

    Topics: Animal Feed; Animals; Bone Marrow Transplantation; Cell Movement; Chronic Disease; Cyclic GMP; Dieta

2012
Beets, bacteria, and blood flow: a lesson of three Bs.
    Circulation, 2012, Oct-16, Volume: 126, Issue:16

    Topics: Animals; Dietary Supplements; Hindlimb; Ischemia; Nitrates

2012
Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat.
    Molecular medicine (Cambridge, Mass.), 2012, Oct-24, Volume: 18

    Topics: Administration, Oral; Animals; Arginine; Ascorbic Acid; Biopterins; Calcium; Drug Synergism; Hindlim

2012
Effect of trapidil in ischemia/reperfusion injury of peripheral nerves.
    Neurosurgery, 2002, Volume: 51, Issue:1

    Topics: Animals; Ischemia; Male; Malondialdehyde; Microscopy, Electron; Myelin Sheath; Nitrates; Nitrites; P

2002
Apoptosis and necrosis after warm ischemia-reperfusion injury of the pig liver and their inhibition by ONO-1714.
    Transplantation, 2003, Mar-15, Volume: 75, Issue:5

    Topics: Amidines; Animals; Apoptosis; Aspartate Aminotransferases; DNA; Enzyme Inhibitors; Female; Hepatocyt

2003
Gut mucosal damage during endotoxic shock is due to mechanisms other than gut ischemia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:5

    Topics: Animals; Blood Pressure; Carbon Dioxide; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Lipopolysa

2003
Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse.
    Circulation, 2004, Aug-31, Volume: 110, Issue:9

    Topics: Aging, Premature; Animals; Aorta, Thoracic; Bone Marrow Transplantation; Collateral Circulation; Cyc

2004
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis.
    Circulation, 2005, Mar-22, Volume: 111, Issue:11

    Topics: Amidohydrolases; Animals; Arginine; Enzyme Induction; Female; Hindlimb; Humans; Ischemia; Laser-Dopp

2005
Overnight changes in the cerebral vascular response to isocapnic hypoxia and hypercapnia in healthy humans: protection against stroke.
    Stroke, 2005, Volume: 36, Issue:11

    Topics: Adult; Brain; Cerebrovascular Circulation; Humans; Hypercapnia; Hypoxia; Ischemia; Male; Middle Cere

2005
Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-22, Volume: 102, Issue:47

    Topics: Animals; Antioxidants; Arginine; Bone Marrow Transplantation; Disease Models, Animal; Fluorescent An

2005
Hypercapnia prevents neovascularization via nitrative stress.
    Free radical biology & medicine, 2006, Feb-01, Volume: 40, Issue:3

    Topics: Animals; Astrocytes; Cell Death; Endothelium, Vascular; Hypercapnia; Ischemia; Neovascularization, P

2006
Portal triad occlusion induces endotoxin tolerance: role of portal congestion.
    The Journal of surgical research, 2006, Volume: 135, Issue:2

    Topics: Animals; Constriction; Cytokines; Endotoxemia; Endotoxins; Hemostasis, Surgical; Interleukin-6; Isch

2006
Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice.
    British journal of pharmacology, 2007, Volume: 150, Issue:7

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hindlimb; Hydroxymethylglutaryl

2007
Peroxynitrite decomposition catalyst FeTMPyP provides partial protection against intestinal ischemia and reperfusion injury in infant rats.
    Pediatric research, 2007, Volume: 62, Issue:1

    Topics: Animals; Animals, Suckling; Endothelial Cells; Glutathione; Intercellular Adhesion Molecule-1; Intes

2007
Essential role of extracellular SOD in reparative neovascularization induced by hindlimb ischemia.
    Circulation research, 2007, Aug-17, Volume: 101, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiati

2007
Effect of nitroglycerin on some parameters of the prooxidant-antioxidant balance and functional state of the liver during ischemia/reperfusion.
    Bulletin of experimental biology and medicine, 2006, Volume: 142, Issue:6

    Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Antioxidants; Aspartate Aminotransferases; Ischemia

2006
In vitro pharmacological study of femoral artery vascular reactivity after inferior canine hindlimb ischemia/reperfusion: effects of in vivo nitric oxide blocker infusion.
    Annals of vascular surgery, 2007, Volume: 21, Issue:5

    Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Endothelium-Dependent Relaxing Factors; Endothelium, Vascu

2007
Somatostatin infusion increases intestinal ischemia and does not improve vasoconstrictor response to norepinephrine in ovine endotoxemia.
    Shock (Augusta, Ga.), 2008, Volume: 30, Issue:5

    Topics: Animals; Endotoxemia; Female; Hemodynamics; Hypotension; Ischemia; Nitrates; Nitrites; Norepinephrin

2008
Activated protein C prevents deleterious effects of remote reperfusion injury caused by intestinal ischemia on wound healing in the left colonic anastomoses: an experimental study in the murine model.
    American journal of surgery, 2008, Volume: 196, Issue:5

    Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Chi-Square Distribution; Glutathione; Glutathi

2008
Ventricular ectopy: etiology, evaluation, and therapy.
    The American journal of medicine, 1982, Volume: 73, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhyth

1982
Interaction between nitric oxide and superoxide: role in modulating leukocyte adhesion in the postischemic microvasculature.
    Transplantation proceedings, 1995, Volume: 27, Issue:5

    Topics: Animals; Cell Adhesion; Endothelium, Vascular; Free Radicals; Humans; Intestine, Small; Ischemia; Le

1995
Reactive species in ischemic rat lung injury: contribution of peroxynitrite.
    The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 1

    Topics: Animals; Arginine; Immunohistochemistry; Ischemia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrat

1995
Nitric oxide and hepatic ischemic injury in human orthotopic liver transplantation.
    Transplantation proceedings, 1995, Volume: 27, Issue:4

    Topics: Cardiac Output; Endotoxins; Female; Humans; Ischemia; Lipopolysaccharides; Liver; Liver Transplantat

1995
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones.
    Journal of medicinal chemistry, 1995, Jan-06, Volume: 38, Issue:1

    Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniqu

1995
Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats.
    Diabetologia, 1996, Volume: 39, Issue:9

    Topics: Acute Kidney Injury; Analysis of Variance; Animals; Arginine; Creatinine; Diabetes Mellitus, Experim

1996
[Role of nitric oxide in warm ischemia of the transplanted kidney].
    Archivos espanoles de urologia, 1997, Volume: 50, Issue:5

    Topics: Animals; Biomarkers; Creatinine; Dogs; Graft Survival; Ischemia; Kidney; Kidney Transplantation; Nep

1997
Xanthine oxidase can generate nitric oxide from nitrate in ischaemia.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Anaerobiosis; Humans; Ischemia; Kinetics; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitric Ox

1997
Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats.
    Free radical biology & medicine, 1998, Volume: 24, Issue:3

    Topics: Animals; Enzyme Inhibitors; Gastric Mucosa; Immune Sera; Ischemia; Leukotriene B4; Lipid Peroxidatio

1998
Inhibition of nitric oxide synthase attenuates peroxynitrite generation, but augments neutrophil accumulation in hepatic ischemia-reperfusion in rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:3

    Topics: Alanine Transaminase; Animals; Enzyme Inhibitors; Intercellular Adhesion Molecule-1; Ischemia; Liver

1998
Direct measurement of nitric oxide release in gastric mucosa during ischemia-reperfusion in rats.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Animals; Electrodes; Enzyme Inhibitors; Gastric Mucosa; Ischemia; Male; NG-Nitroarginine Methyl Este

1998
Differential effect of 2-aminoethyl-isothiourea, an inhibitor of the inducible nitric oxide synthase, on microvascular blood flow and organ injury in models of hepatic ischemia-reperfusion and endotoxemia.
    Shock (Augusta, Ga.), 1998, Volume: 10, Issue:1

    Topics: Alanine Transaminase; Animals; beta-Aminoethyl Isothiourea; Blood Circulation; Blood Pressure; Endot

1998
Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development.
    European journal of pharmacology, 1998, Jun-26, Volume: 351, Issue:3

    Topics: Animals; Cell Death; Cerebral Infarction; Coumarins; Enzyme Inhibitors; Ischemia; L-Lactate Dehydrog

1998
NO modulates P-selectin and ICAM-1 mRNA expression and hemodynamic alterations in hepatic I/R.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Alanine Transaminase; Animals; Cell Adhesion Molecules; Hemodynamics; Intercellular Adhesion Molecul

1998
Antiischemic therapy in patients with coronary heart disease living in long-term care. Systematic Assessment of Geriatric Drug Use by Epidemiology (SAGE) Group.
    Pharmacotherapy, 1999, Volume: 19, Issue:5

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Calcium Channel Blockers; Cardiovascular Diseases; C

1999
IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Celiac Artery; Constriction; Cytokines

1999
Role of endogenous nitric oxide in TNF-alpha and IL-1beta generation in hepatic ischemia-repefusion.
    Shock (Augusta, Ga.), 2000, Volume: 13, Issue:3

    Topics: Alanine Transaminase; Animals; Down-Regulation; Enzyme Inhibitors; Interleukin-1; Ischemia; Leukocyt

2000
Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Animals; Arterial Occlusive Diseases; Chemotaxis, Leukocyte; DNA Damage; Energy Metabolism; Enzyme I

2000
Prostaglandin E1 reduces ischemia/reperfusion injury by normalizing nitric oxide and superoxide release.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Acetylcholine; Alprostadil; Animals; Drug Evaluation, Preclinical; Hindlimb; Ischemia; Male; Muscle,

2000
Nitric oxide synthase and tissue injury.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Alprostadil; Animals; Arginine; Burns; Enzyme Inhibitors; Humans; Ischemia; Luminescent Measurements

2000
Evidence for peroxynitrite formation in renal ischemia-reperfusion injury: studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-Iminoethyl)lysine.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Animals; Enzyme Inhibitors; Ischemia; Kidney; Lysine; Male; Nitrates; Nitric Oxide; Nitric Oxide Syn

2000
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation;

2000
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:12

    Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Dis

2000
Ascorbic acid improves postischemic vasodilatation impaired by infusion of soybean oil into canine iliac artery.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:6

    Topics: Animals; Ascorbic Acid; Cholesterol; Coronary Circulation; Dogs; Enzyme Inhibitors; Fat Emulsions, I

2000
Effects of nitric oxide on normal and ischemic cochlea of the guinea pig.
    Experimental neurology, 2001, Volume: 169, Issue:1

    Topics: Animals; Catalase; Cell Count; Cochlea; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitor

2001
Inhibition of nitric oxide synthase does not influence urinary nitrite plus nitrate excretion after renal ischemic injury.
    Langenbeck's archives of surgery, 2002, Volume: 386, Issue:7

    Topics: Animals; Disease Models, Animal; Ischemia; Kidney; Kidney Tubules; Male; NG-Nitroarginine Methyl Est

2002
Stenosis-dependent role of nitric oxide and prostaglandins in chronic renal ischemia.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Chronic Disease; Dinoprostone

2002
A novel inhibitor of inducible nitric oxide synthase (ONO-1714) prevents critical warm ischemia-reperfusion injury in the pig liver.
    Transplantation, 2002, May-15, Volume: 73, Issue:9

    Topics: Amidines; Animals; Aspartate Aminotransferases; Enzyme Inhibitors; Female; Heterocyclic Compounds, 2

2002
The flux of arginine after ischemia-reperfusion in the rat kidney.
    Kidney international, 2002, Volume: 62, Issue:1

    Topics: Amino Acids; Animals; Arginase; Arginine; Ischemia; Kidney; Male; Nitrates; Nitric Oxide; Rats; Rats

2002
[Effects of isosorbide dinitrate of prolonged action on the prevention of myocardial ischemia induced by exercise: correlation with nitrate blood levels].
    Arquivos brasileiros de cardiologia, 1975, Volume: 28, Issue:3

    Topics: Adult; Aged; Coronary Disease; Delayed-Action Preparations; Drug Evaluation; Female; Heart Function

1975
Detection of endothelial-derived relaxing factor in human plasma in the basal state and following ischemia using electron paramagnetic resonance spectrometry.
    Analytical biochemistry, 1990, Volume: 187, Issue:2

    Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Hemoglobins; Humans; Ischemia; Nitrates; Nitric

1990
Nifedipine-induced hypotension and mesenteric ischemia.
    Southern medical journal, 1989, Volume: 82, Issue:2

    Topics: Adrenergic beta-Antagonists; Calcium Chloride; Drug Therapy, Combination; Hemodynamics; Humans; Hypo

1989
Uranyl nitrate-induced acute renal failure in the rat: micropuncture and renal hemodynamic studies.
    Kidney international, 1974, Volume: 6, Issue:6

    Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Blood Urea Nitrogen; Coloring Agents; Glomerular

1974
Tetracycline toxicity.
    Experientia, 1966, Aug-15, Volume: 22, Issue:8

    Topics: Acute Kidney Injury; Animals; Chromates; Female; Glomerular Filtration Rate; Ischemia; Nitrates; Rat

1966