Page last updated: 2024-10-19

nitrates and Inflammatory Response Syndrome, Systemic

nitrates has been researched along with Inflammatory Response Syndrome, Systemic in 25 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"Hyperglycemia is frequently observed in nondiabetic patients during acute illness."1.35Hyperglycemia contributes to cardiac dysfunction in a lipopolysaccharide-induced systemic inflammation model. ( Asai, N; Hagiwara, S; Hasegawa, A; Iwasaka, H; Noguchi, T, 2009)
"Hypercalcemia was produced in the conscious rat and isolated perfused lungs."1.35The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs. ( Chen, HI; Kao, SJ; Yeh, DY, 2008)
"Nitric oxide overproduction in sepsis syndrome was suspected to be responsible for hemodynamic derangement and, by induction of lipid peroxidation, for tissue damage."1.32High and low response in relation to nitric oxide formation but not to lipid peroxidation in patients with sepsis. ( Kox, WJ; Kuppe, H; Petersson, AS; Richter, N; Rohr, U; Schimke, I; Wauer, H; Wennmalm, A, 2003)
"Infection is a microbial phenomenon characterized by an inflammatory response to the presence of microorganism."1.32Relationships of circulating nitrite/nitrate levels to severity and multiple organ dysfunction syndrome in systemic inflammatory response syndrome. ( Hirata, Y; Hirokawa, M; Imai, T; Mitaka, C; Nosaka, T; Wakimoto, H; Yokoyama, K, 2003)
" In conclusion, the chronic use of NAC inhibited MPO activity and lipid peroxidation, which resulted in reduction of apoptosis in lung in this CLP model."1.32The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. ( Avlan, D; Cinel, I; Cinel, L; Dikmengil, M; Koksel, O; Okcu, H; Oral, U; Ozdulger, A; Unlu, A, 2003)
"To determine in children with sepsis syndrome and septic shock the time course of nitric oxide metabolites: nitrate and nitrite (nitrogen oxides)."1.30Activation of the L-arginine nitric oxide pathway in severe sepsis. ( Duke, T; South, M; Stewart, A, 1997)
"Thirty-one children with the sepsis syndrome, 18 of whom were also hypotensive."1.29Increased serum nitrite and nitrate concentrations in children with the sepsis syndrome. ( Burckart, G; Carcillo, JA; Janosky, JE; Shah, N; Wong, HR, 1995)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (40.00)18.2507
2000's10 (40.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, SC1
Hsu, JS1
Li, CC1
Chen, KM1
Liu, CT1
Hagiwara, S1
Iwasaka, H1
Hasegawa, A1
Asai, N1
Noguchi, T1
Delbin, MA1
Davel, AP1
Rossoni, LV1
Antunes, E1
Zanesco, A1
Impellizzeri, D1
Mazzon, E1
Di Paola, R1
Paterniti, I1
Bramanti, P1
Cuzzocrea, S1
Osterbur, K1
Whitehead, Z1
Sharp, CR1
DeClue, AE1
Kothari, N1
Bogra, J1
Kohli, M1
Malik, A1
Kothari, D1
Srivastava, S1
Keshari, RS1
Singh, V1
Barthwal, MK1
Dikshit, M1
Alonso de Vega, JM1
Díaz, J1
Serrano, E1
Carbonell, LF1
Mitaka, C2
Yokoyama, K2
Morimoto, T1
Nosaka, T2
Sunamori, M1
Imai, T2
Schimke, I1
Richter, N1
Wauer, H1
Rohr, U1
Petersson, AS1
Wennmalm, A1
Kuppe, H1
Kox, WJ1
Hirata, Y1
Wakimoto, H1
Hirokawa, M1
Ozdulger, A1
Cinel, I1
Koksel, O1
Cinel, L1
Avlan, D1
Unlu, A1
Okcu, H1
Dikmengil, M1
Oral, U1
Noble, F1
Rubira, E1
Boulanouar, M1
Palmier, B1
Plotkine, M1
Warnet, JM1
Marchand-Leroux, C1
Massicot, F1
Chen, HI1
Yeh, DY1
Kao, SJ1
Wong, HR2
Carcillo, JA2
Burckart, G2
Shah, N1
Janosky, JE1
Wong, ML1
Rettori, V1
al-Shekhlee, A1
Bongiorno, PB1
Canteros, G1
McCann, SM1
Gold, PW1
Licinio, J1
Kaplan, SS1
Takano, H1
Yoshikawa, T1
Yamaguchi, T1
Hongo, H1
Fujii, T1
Boku, Y1
Yoshida, N1
Yamamoto, H1
Nakahashi, Y1
Yanagisawa, R1
Kondo, M1
Duke, T1
South, M1
Stewart, A1
Spack, L1
Havens, PL1
Griffith, OW1
Schwartz, D1
Mendonca, M1
Schwartz, I1
Xia, Y1
Satriano, J1
Wilson, CB1
Blantz, RC1
Harper, R1
Parkhouse, N1
Green, C1
Martin, R1
Takakuwa, T1
Endo, S1
Inada, K1
Kasai, T1
Yamada, Y1
Ogawa, M1
Torre, D1
Tambini, R1
Aristodemo, S1
Goglio, A1
Airoldi, M1
Papathanassoglou, ED1
Moynihan, JA1
Vermillion, DL1
McDermott, MP1
Ackerman, MH1
Liu, P1
Xu, B1
Hock, CE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oxidative Stress Related to 2 Different Oxygen Concentrations During General Anesthesia. Clinical Trial.[NCT02619214]Phase 460 participants (Anticipated)Interventional2013-05-31Recruiting
Impact of Early CRRT Intervention in Patients Receiving VA-ECMO Support on 30-day Mortality: A Randomized Controlled Trial[NCT03549923]Phase 4550 participants (Anticipated)Interventional2018-12-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for nitrates and Inflammatory Response Syndrome, Systemic

ArticleYear
Serum levels of nitrite and nitrate in patients with systemic inflammatory response syndrome.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:3

    Topics: Adult; Aged; Bacterial Infections; Biomarkers; Female; Humans; Male; Middle Aged; Nitrates; Nitrites

1999

Other Studies

24 other studies available for nitrates and Inflammatory Response Syndrome, Systemic

ArticleYear
Protective effect of leaf essential oil from Cinnamomum osmophloeum Kanehira on endotoxin-induced intestinal injury in mice associated with suppressed local expression of molecules in the signaling pathways of TLR4 and NLRP3.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Carrier Proteins; Cinnamomum; Cytokines; Disease Mod

2015
Hyperglycemia contributes to cardiac dysfunction in a lipopolysaccharide-induced systemic inflammation model.
    Critical care medicine, 2009, Volume: 37, Issue:7

    Topics: Animals; Cytokines; Disease Models, Animal; HMGB1 Protein; Hyperglycemia; Hypoglycemic Agents; Insul

2009
Beneficial effects of physical training on the cardio-inflammatory disorder induced by lung ischemia/reperfusion in rats.
    Inflammation, 2011, Volume: 34, Issue:5

    Topics: Animals; Interleukin-6; Lung Injury; Male; Mesenteric Arteries; NADPH Oxidases; Nitrates; Nitrites;

2011
Effect of NADPH-oxidase inhibitors in the experimental model of zymosan-induced shock in mice.
    Free radical research, 2011, Volume: 45, Issue:7

    Topics: Acetophenones; Animals; Apoptosis; Cytokines; Enzyme Inhibitors; Male; Mice; Multiple Organ Failure;

2011
Plasma nitrate/nitrite concentrations in dogs with naturally developing sepsis and non-infectious forms of the systemic inflammatory response syndrome.
    The Veterinary record, 2011, Nov-19, Volume: 169, Issue:21

    Topics: Animals; Dog Diseases; Dogs; Female; Male; Nitrates; Nitrites; Predictive Value of Tests; Prospectiv

2011
Role of active nitrogen molecules in progression of septic shock.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:3

    Topics: Adult; APACHE; Creatinine; Critical Care; Critical Illness; Disease Progression; Enzyme-Linked Immun

2012
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
Oxidative stress in critically ill patients with systemic inflammatory response syndrome.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Cohort Studies; Critical Illness; Female; Humans

2002
An increase in urinary nitrite/nitrate excretion is associated with the hyperdynamic state after cardiovascular surgery.
    Intensive care medicine, 2002, Volume: 28, Issue:8

    Topics: Aged; Aged, 80 and over; Cardiopulmonary Bypass; Cardiovascular Agents; Cardiovascular Diseases; Chr

2002
High and low response in relation to nitric oxide formation but not to lipid peroxidation in patients with sepsis.
    Critical care medicine, 2003, Volume: 31, Issue:1

    Topics: Adult; Aged; Arginine; Case-Control Studies; Female; Gas Chromatography-Mass Spectrometry; Humans; L

2003
Relationships of circulating nitrite/nitrate levels to severity and multiple organ dysfunction syndrome in systemic inflammatory response syndrome.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Aged; Aged, 80 and over; APACHE; Female; Humans; Infections; Male; Middle Aged; Multiple Organ Failu

2003
The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; Cecum; Disease Models, Animal; Intestinal Perforation; Ligation;

2003
Acute systemic inflammation induces central mitochondrial damage and mnesic deficit in adult Swiss mice.
    Neuroscience letters, 2007, Sep-07, Volume: 424, Issue:2

    Topics: Animals; Behavior, Animal; Cognition Disorders; Cyclooxygenase 2; Disease Models, Animal; Glutathion

2007
The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs.
    Journal of biomedical science, 2008, Volume: 15, Issue:2

    Topics: Animals; Calcitonin; Capillary Permeability; Cytokines; Hypercalcemia; Lysine; Male; Methylguanidine

2008
Increased serum nitrite and nitrate concentrations in children with the sepsis syndrome.
    Critical care medicine, 1995, Volume: 23, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Hypotension; Infant; Infant, Newborn; Male; Nit

1995
Inducible nitric oxide synthase gene expression in the brain during systemic inflammation.
    Nature medicine, 1996, Volume: 2, Issue:5

    Topics: Animals; Brain; Citrulline; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hypothalamus,

1996
Nitric oxide production in critically ill patients.
    Archives of disease in childhood, 1996, Volume: 74, Issue:6

    Topics: Child; Critical Illness; Graft Rejection; Humans; Infections; Nitrates; Nitric Oxide; Nitrites; Orga

1996
Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats.
    European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1

    Topics: Animals; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Injections, Intrav

1997
Activation of the L-arginine nitric oxide pathway in severe sepsis.
    Archives of disease in childhood, 1997, Volume: 76, Issue:3

    Topics: Adolescent; Arginine; Biomarkers; Child; Child, Preschool; Female; Humans; Infant; Male; Multiple Or

1997
Measurements of total plasma nitrite and nitrate in pediatric patients with the systemic inflammatory response syndrome.
    Critical care medicine, 1997, Volume: 25, Issue:6

    Topics: Child, Preschool; Cohort Studies; Humans; Infant; Infant, Newborn; Nitrates; Nitrites; Predictive Va

1997
Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats.
    The Journal of clinical investigation, 1997, Jul-15, Volume: 100, Issue:2

    Topics: Animals; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Glomerular Filtration Rate; GTP Cyclohydrola

1997
Nitric oxide production in burns: plasma nitrate levels are not increased in patients with minor thermal injuries.
    The Journal of trauma, 1997, Volume: 43, Issue:3

    Topics: Adult; Aged; Burns; Case-Control Studies; Female; Humans; Male; Middle Aged; Multiple Organ Failure;

1997
Assessment of inflammatory cytokines, nitrate/nitrite, type II phospholipase A2, and soluble adhesion molecules in systemic inflammatory response syndrome.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:1

    Topics: Adult; Aged; Cell Adhesion Molecules; Cytokines; Endotoxins; Enzyme-Linked Immunosorbent Assay; Fema

1997
Soluble fas levels correlate with multiple organ dysfunction severity, survival and nitrate levels, but not with cellular apoptotic markers in critically ill patients.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Biomarkers; Critical Illness; Diagnosis-Related Groups; F

2000
Inhibition of nitric oxide synthesis by L-name exacerbates acute lung injury induced by hepatic ischemia-reperfusion.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:3

    Topics: Alanine Transaminase; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibito

2001