nitrates has been researched along with Inflammation in 273 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anti-inflammatory effects of hydrofluoroalkane-beclomethasone are similar to those of fluticasone DPI in children with moderate persistent asthma." | 9.13 | Comparison of the anti-inflammatory effects of extra-fine hydrofluoroalkane-beclomethasone vs fluticasone dry powder inhaler on exhaled inflammatory markers in childhood asthma. ( Damoiseaux, JG; Dompeling, E; Hendriks, HJ; Jöbsis, Q; Kester, AD; Rijkers, GT; Robroeks, CM; van de Kant, KD; van Vliet, D; Wodzig, WK, 2008) |
| "Finally, this study illustrated that agmatine attenuates the allergic inflammation of airways caused by OVA by mitigating cytokines release, NO expression, and oxidative stress." | 8.12 | Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. ( Abdelaziz, RR; Elmahdi, HS; Suddek, GM; Еlmahdy, MK, 2022) |
| "The anti-inflammatory effect on contact dermatitis of the water solubilized 1'-Acetoxychavicol Acetate (ACA) by complexation with β-1,3-glucan isolated form Aureobasidium pullulans black yeast is reported." | 7.81 | Anti-inflammatory effect of water-soluble complex of 1'-acetoxychavicol acetate with highly branched β-1,3-glucan on contact dermatitis. ( Aizawa, Y; Azuma, H; Hiramoto, K; Ikeda, A; Kasahara, E; Li, J; Nagasaki, T; Suzuki, T; Tsuruta, D, 2015) |
| "The aim of this study was to evaluate the protective effect of the sulfated-polysaccharide (PLS) fraction extracted from the seaweed Gracilaria birdiae in rats with trinitrobenzenesulfonic acid (TNBS)-induced colitis." | 7.80 | Sulfated-polysaccharide fraction extracted from red algae Gracilaria birdiae ameliorates trinitrobenzenesulfonic acid-induced colitis in rats. ( Aragão, KS; Barbosa, AL; Batista, JA; Brito, TV; Chaves, LS; Franco, AX; Freitas, AL; Júnior, JS; Medeiros, JV; Neto, JP; Prudêncio, RS; Silva, RO; Soares, PM; Souza, MH, 2014) |
| " In this study, the anti-inflammatory properties of anethole in animal models of nonimmune acute inflammation such as croton oil-induced ear edema and carrageenan-induced pleurisy were investigated." | 7.79 | Inhibitory effect of anethole in nonimmune acute inflammation. ( Bersani-Amado, CA; Caparroz-Assef, SM; Cuman, RK; Dalalio, MM; Domiciano, TP; Estevão-Silva, CF; Ramos, FS; Ritter, AM; Silva, EL, 2013) |
| "Parenteral arginine administration at approximately 4% of total calories may alter PBLs and splenocytic immunity, and >6% of total calories might not be of benefit in rats with subacute peritonitis." | 7.78 | Appropriate dose of parenteral arginine enhances immunity of peripheral blood cells and splenocytes in rats with subacute peritonitis. ( Chen, YH; Hsiao, CC; Hsu, LS; Lee, CH; Lo, HC, 2012) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 7.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| "Effects of different doses of aspirin, compared to equimolar doses of nitric oxide (NO)-donating aspirin (NCX 4016), and of a single dose of paracetamol, compared to an equimolar dose of NO-donating paracetamol (NCX 701) were investigated in acute zymosan-induced air pouch inflammation in rats." | 7.74 | Effect of aspirin, paracetamol and their nitric oxide donating derivatives on exudate cytokine and PGE2 production in zymosan-induced air pouch inflammation in rats. ( Mamuk, S; Melli, M, 2007) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 7.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| "Nitrites/nitrates were significantly lower (P < 0." | 6.72 | Effect of doxazosin on C-reactive protein plasma levels and on nitric oxide in patients with hypertension. ( Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, R; Galli, S; Gravina, A; Montagna, L; Paniga, S; Piccinni, MN; Pricolo, F; Salvadeo, S; Tinelli, C, 2006) |
| "Importantly, the Pb-induced lung inflammation and apoptosis were associated with a proportional increase in the expression of NF-κB and AhR mRNAs and proteins." | 5.72 | Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways. ( Ahmad, SF; Al-Alallah, IA; Alanazi, FE; Aljarboa, SA; Attafi, IM; Bakheet, SA; Belali, OM; Korashy, HM, 2022) |
| "Sepsis is caused by a dysregulated host response to infection, often associated with acute central nervous system (CNS) dysfunction, which results in long-term cognitive impairment." | 5.48 | Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis. ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018) |
| "Ischemia was followed by a significant increase in muscle myeloperoxidase activity, as well as interleukin-6 and thiobarbituric acid reactive substances species levels." | 5.48 | N-acetylcysteine effects on a murine model of chronic critical limb ischemia. ( Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F, 2018) |
| "Asiatic acid is a triterpenoid isolated from Centella asiatica." | 5.40 | Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats. ( Bunbupha, S; Khrisanapant, W; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P, 2014) |
| "Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes." | 5.39 | Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. ( Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA, 2013) |
| "Inflammation is difficult to control when it spreads throughout the body and often progresses into multiple organ dysfunction, eventually leading to death." | 5.37 | Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation. ( Hagiwara, S; Hasegawa, A; Koga, H; Kudo, K; Kusaka, J; Noguchi, T, 2011) |
| "Cimetidine (CIM) is an H2-receptor antagonist that has been used in racehorses in an attempt to reduce the occurrence of stress-related gastric ulceration." | 5.30 | Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse. ( Dees, AA; Hunter, RP; Keowen, ML; Koch, CE; McClure, JR; Short, CR; VanSteenhouse, JL, 1999) |
| "Eleven steroid-naive adults with mild-to-moderate persistent asthma were treated with mometasone furoate dry powder inhaler, 400 microg/d, for 8 weeks, followed by a 4-week washout." | 5.14 | Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma. ( Berro, A; Casale, TB; Mehta, V; Romero, FA; Stokes, JR, 2009) |
| "The anti-inflammatory effects of hydrofluoroalkane-beclomethasone are similar to those of fluticasone DPI in children with moderate persistent asthma." | 5.13 | Comparison of the anti-inflammatory effects of extra-fine hydrofluoroalkane-beclomethasone vs fluticasone dry powder inhaler on exhaled inflammatory markers in childhood asthma. ( Damoiseaux, JG; Dompeling, E; Hendriks, HJ; Jöbsis, Q; Kester, AD; Rijkers, GT; Robroeks, CM; van de Kant, KD; van Vliet, D; Wodzig, WK, 2008) |
| "Finally, this study illustrated that agmatine attenuates the allergic inflammation of airways caused by OVA by mitigating cytokines release, NO expression, and oxidative stress." | 4.12 | Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. ( Abdelaziz, RR; Elmahdi, HS; Suddek, GM; Еlmahdy, MK, 2022) |
| " Accordingly, this study investigated the influence of the novel JAK inhibitor ruxolitinib (RXB) on concanavalin A (Con A)-induced hepatitis and systemic hyperinflammation in mice to simulate the context occurring in COVID-19 patients." | 4.12 | The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice. ( El-Mesery, M; Hazem, SH; Hendawy, OM; Shaker, ME, 2022) |
| "The similar functional and molecular responses to beetroot and sodium nitrate indicate that the nitrate content of beetroot reduced inflammation and improved cardiovascular, liver, and metabolic function in rats with metabolic syndrome, rather than betanin." | 3.85 | Beetroot and Sodium Nitrate Ameliorate Cardiometabolic Changes in Diet-Induced Obese Hypertensive Rats. ( Bhaswant, M; Brown, L; Mathai, ML; McAinch, AJ, 2017) |
| " Serum markers of inflammation (high-sensitivity C-reactive protein) and endothelial function (soluble intercell adhesion molecule-1, vascular cell adhesion molecule-1, E-selectin, endothelin-1 and total nitrite) were assessed using nephelometry, immunoassays and spectroscopy." | 3.81 | Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy. ( Jenkins, AJ; Nguyen, TT; Sasongko, MB; Shaw, JE; Wang, JJ; Wong, TY, 2015) |
| "The anti-inflammatory effect on contact dermatitis of the water solubilized 1'-Acetoxychavicol Acetate (ACA) by complexation with β-1,3-glucan isolated form Aureobasidium pullulans black yeast is reported." | 3.81 | Anti-inflammatory effect of water-soluble complex of 1'-acetoxychavicol acetate with highly branched β-1,3-glucan on contact dermatitis. ( Aizawa, Y; Azuma, H; Hiramoto, K; Ikeda, A; Kasahara, E; Li, J; Nagasaki, T; Suzuki, T; Tsuruta, D, 2015) |
| "The aim of this study was to evaluate the protective effect of the sulfated-polysaccharide (PLS) fraction extracted from the seaweed Gracilaria birdiae in rats with trinitrobenzenesulfonic acid (TNBS)-induced colitis." | 3.80 | Sulfated-polysaccharide fraction extracted from red algae Gracilaria birdiae ameliorates trinitrobenzenesulfonic acid-induced colitis in rats. ( Aragão, KS; Barbosa, AL; Batista, JA; Brito, TV; Chaves, LS; Franco, AX; Freitas, AL; Júnior, JS; Medeiros, JV; Neto, JP; Prudêncio, RS; Silva, RO; Soares, PM; Souza, MH, 2014) |
| " In this study, the anti-inflammatory properties of anethole in animal models of nonimmune acute inflammation such as croton oil-induced ear edema and carrageenan-induced pleurisy were investigated." | 3.79 | Inhibitory effect of anethole in nonimmune acute inflammation. ( Bersani-Amado, CA; Caparroz-Assef, SM; Cuman, RK; Dalalio, MM; Domiciano, TP; Estevão-Silva, CF; Ramos, FS; Ritter, AM; Silva, EL, 2013) |
| "Leukotrienes (LT), isoprostanes, and nitrites/nitrates are biomarkers of airway inflammation and oxidative stress that can be detected in exhaled breath condensate (EBC)." | 3.79 | Markers of airway inflammation in the exhaled breath condensate of preschool wheezers. ( Belda, J; Caballero, S; Escribano, A; Martorell, A, 2013) |
| "Parenteral arginine administration at approximately 4% of total calories may alter PBLs and splenocytic immunity, and >6% of total calories might not be of benefit in rats with subacute peritonitis." | 3.78 | Appropriate dose of parenteral arginine enhances immunity of peripheral blood cells and splenocytes in rats with subacute peritonitis. ( Chen, YH; Hsiao, CC; Hsu, LS; Lee, CH; Lo, HC, 2012) |
| " MRFs (serum lipid profile, insulin resistance indexes, blood pressure) in addition to uric acid, homocysteine, leptin, and inflammatory markers were measured." | 3.77 | Nitric oxide production is increased in severely obese children and related to markers of oxidative stress and inflammation. ( Alonso-Iglesias, E; Codoñer-Franch, P; Megías-Vericat, J; Murria-Estal, R; Tavárez-Alonso, S; Tortajada-Girbés, M, 2011) |
| " Previously, we reported an increase in protein tyrosine nitration (a marker of oxidative/nitrosative damage) and a decrease in the antioxidant enzyme extracellular superoxide dismutase (EC-SOD) in the lungs of young mice during endotoxemia-induced SIRS." | 3.77 | The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation. ( Evers, BM; Saito, H; Starr, ME; Ueda, J; Yamamoto, S, 2011) |
| "Specific dietary polyphenols, in particular quercetin and theaflavin, may attenuate atherosclerosis in ApoE(-/-) gene-knockout mice by alleviating inflammation, improving NO bioavailability, and inducing heme oxygenase-1." | 3.76 | Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction. ( Croft, KD; Hime, N; Hodgson, JM; Loke, WM; Magat, M; McKinley, AJ; Proudfoot, JM; Stocker, R, 2010) |
| " Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1." | 3.76 | Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010) |
| " After treatment with celecoxib, the hypertension was attenuated (MAP=126±2 mm Hg) in obese rats without changes in HR." | 3.76 | Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats. ( Cecchini, R; Cunha, NV; de Abreu, SB; Grassiolli, S; Guarnier, FA; Martins-Pinge, MC; Mazzuco, TL; Panis, C; Pinge-Filho, P, 2010) |
| " This study addressed whether rosiglitazone (ROSI), a PPARgamma agonist, attenuates salt-sensitive hypertension in intact (INT) and OVX DS rats, and if so, whether insulin resistance, nitric oxide (NO), oxidative stress, and/or renal inflammation were contributing mediators." | 3.76 | Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats. ( Jones, AV; Lamarca, BB; Racusen, LC; Reckelhoff, JF; Romero, DG; Ryan, MJ; Sartori-Valinotti, JC; Venegas-Pont, MR; Yanes, LL, 2010) |
| " Inflammation was analysed using the measurement of nitric oxide, pH and concentration of nitrites, nitrates and isoprostane in the exhaled air condensate." | 3.75 | [Inflammation markers in the exhaled air of patients with bronchiectasis unassociated with cystic fibrosis]. ( Cortijo, J; de Diego Damiá, A; Fullana, J; León, M; Martínez-Moragón, E; Palop-Cervera, M, 2009) |
| "Effects of different doses of aspirin, compared to equimolar doses of nitric oxide (NO)-donating aspirin (NCX 4016), and of a single dose of paracetamol, compared to an equimolar dose of NO-donating paracetamol (NCX 701) were investigated in acute zymosan-induced air pouch inflammation in rats." | 3.74 | Effect of aspirin, paracetamol and their nitric oxide donating derivatives on exudate cytokine and PGE2 production in zymosan-induced air pouch inflammation in rats. ( Mamuk, S; Melli, M, 2007) |
| " We evaluated the relationship between TNF-alpha and iNOS expression in indomethacin-induced jejunoileitis in male Sprague-Dawley rats." | 3.73 | Inhibition of TNF-alpha improves indomethacin-induced enteropathy in rats by modulating iNOS expression. ( Finocchiaro, S; Levine, RA; Nandi, J; Ong, G; Saud, B, 2005) |
| "Fifty-one consecutive children with sepsis and six critically ill children without sepsis were enrolled and given 18 mg/kg antipyrine per NG." | 3.72 | Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure. ( Burckart, GJ; Carcillo, JA; Doughty, L; Frye, RF; Kaplan, SS; Kofos, D; Sasser, H, 2003) |
| " Thus, the objective of this study was to assess the role of iNOS in modulating neutrophil (PMN) extravasation in an oyster glycogen-induced model of acute peritonitis in rats." | 3.70 | Role of inducible nitric oxide synthase in leukocyte extravasation in vivo. ( Cockrell, A; Gray, L; Grisham, MB; Jourd'heuil, D; Kawachi, S; Laroux, FS; Van der Heyde, H, 1999) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 3.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| " Chronic intestinal inflammation was induced in rats with indomethacin (7." | 3.70 | Antiinflammatory actions of cat's claw: the role of NF-kappaB. ( Charbonnet, RM; Clark, DA; Liu, X; Mannick, EE; Miller, MJ; Sadowska-Krowicka, H; Sandoval-Chacón, M; Thompson, JH; Zhang, XJ, 1998) |
| " The diclofenac derivative, 'nitrofenac', was examined in terms of its ability to induce acute gastric erosions and chronic-type gastric ulcers in rats and rabbits, respectively." | 3.69 | A diclofenac derivative without ulcerogenic properties. ( Cicala, C; Cirino, G; Grisham, M; McKnight, W; Reuter, B; Wallace, JL, 1994) |
| "Aging is associated with a vasoconstrictive, pro-coagulant, and pro-inflammatory profile of arteries and a decline in the bioavailability of the endothelium-derived molecule nitric oxide." | 2.84 | Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study. ( Allen, JD; Briskey, D; Fassett, R; Hickey, D; Kerr, G; Leveritt, M; Neubauer, O; Ortiz de Zevallos Munoz, J; Parker, TJ; Peake, JM; Pecheniuk, NM; Raubenheimer, K, 2017) |
| "Nitrites/nitrates were significantly lower (P < 0." | 2.72 | Effect of doxazosin on C-reactive protein plasma levels and on nitric oxide in patients with hypertension. ( Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, R; Galli, S; Gravina, A; Montagna, L; Paniga, S; Piccinni, MN; Pricolo, F; Salvadeo, S; Tinelli, C, 2006) |
| "The anti-inflammatory potential of azithromycin in chronic obstructive pulmonary disease (COPD) patients was explored following a standard oral dosing regimen." | 2.71 | Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment. ( Barisić, K; Bosnar, M; Brajsa, K; Cepelak, I; Culić, O; Cuzić, S; Eraković, V; Glojnarić, I; Manojlović, Z; Munić, V; Novak-Mircetić, R; Oresković, K; Parnham, MJ; Pavicić-Beljak, V; Popović-Grle, S; Radosević, S; Sucić, M, 2005) |
| " Relevant areas of interest include the search for safe and effective treatment strategies that combine neuroprotection reperfusion, better use of advanced brain imaging for patient selection, and wider implementation of prehospital conducted clinical trials." | 2.53 | Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation. ( Chamorro, Á; Dirnagl, U; Planas, AM; Urra, X, 2016) |
| "Obesity, type 2 diabetes and the metabolic syndrome are associated with a decrease in NO bioavailability." | 2.53 | Dietary inorganic nitrate: From villain to hero in metabolic disease? ( Griffin, JL; McNally, B; Roberts, LD, 2016) |
| "Myalgic encephalomyelitis (ME), chronic fatigue syndrome (CFS) and chronic fatigue (CF) are distinct diagnostic categories with regard to clinical symptoms, severity of illness and biomarkers." | 2.49 | Inflammatory and oxidative and nitrosative stress cascades as new drug targets in myalgic encephalomyelitis and chronic fatigue syndrome. ( Maes, M, 2013) |
| "Pancreatic cancer is the most deadly of all gastrointestinal malignancies with near zero five-year survival." | 2.43 | NF-kappaB, inflammation and pancreatic carcinogenesis: NF-kappaB as a chemoprevention target (review). ( Rigas, B; Zhang, Z, 2006) |
| "In influenza virus infection in mice, the level of xanthine oxidase (XO) at the infected sites was elevated to a great extent." | 2.40 | Nitric oxide and oxygen radicals in infection, inflammation, and cancer. ( Akaike, T; Maeda, H, 1998) |
| "Several human cancers are associated with chronic bacterial, viral and parasitic infections." | 2.39 | Potential genotoxicity of chronically elevated nitric oxide: a review. ( Hotchkiss, JH; Liu, RH, 1995) |
| "Importantly, the Pb-induced lung inflammation and apoptosis were associated with a proportional increase in the expression of NF-κB and AhR mRNAs and proteins." | 1.72 | Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways. ( Ahmad, SF; Al-Alallah, IA; Alanazi, FE; Aljarboa, SA; Attafi, IM; Bakheet, SA; Belali, OM; Korashy, HM, 2022) |
| "Ischemia was followed by a significant increase in muscle myeloperoxidase activity, as well as interleukin-6 and thiobarbituric acid reactive substances species levels." | 1.48 | N-acetylcysteine effects on a murine model of chronic critical limb ischemia. ( Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F, 2018) |
| "Sepsis is caused by a dysregulated host response to infection, often associated with acute central nervous system (CNS) dysfunction, which results in long-term cognitive impairment." | 1.48 | Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis. ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018) |
| "Chronic inflammation is currently recognized as a critical process in modern-era epidemics such as diabetes, obesity and neurodegeneration." | 1.43 | Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome. ( Laranjinha, J; Nunes, C; Rocha, BS, 2016) |
| "Aging and obesity are associated with raised oxidative stress and a reduction of nitric oxide (NO) bioavailability, with subsequent decline in insulin sensitivity and endothelial function." | 1.43 | Inorganic Nitrate Supplementation in Young and Old Obese Adults Does Not Affect Acute Glucose and Insulin Responses but Lowers Oxidative Stress. ( Ashor, AW; Brandt, K; Chowdhury, S; Ishaq, A; Mathers, JC; Oggioni, C; Qadir, O; Saretzki, G; Siervo, M, 2016) |
| "Obesity is a risk factor for the development of human colorectal cancer (CC)." | 1.43 | Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer. ( Amor, S; Barrios, V; Fernandez, N; Ferrero, E; García-Villalón, AL; García-Villar, O; Granado, M; Iglesias-de la Cruz, MC; Monge, L, 2016) |
| "The experimental model of pleurisy was induced in mice by a single intrapleural injection of carrageenan (1 %)." | 1.40 | Croton antisyphiliticus Mart. attenuates the inflammatory response to carrageenan-induced pleurisy in mice. ( de Carvalho, FK; Dos Reis, GO; Fröde, TS; Heller, M; Micke, GA; Pizzolatti, MG; Vicente, G, 2014) |
| "Asiatic acid is a triterpenoid isolated from Centella asiatica." | 1.40 | Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats. ( Bunbupha, S; Khrisanapant, W; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P, 2014) |
| "Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes." | 1.39 | Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. ( Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA, 2013) |
| "Endotoxic shock was induced by lipopolysaccharide (LPS) in male Balb/c mice." | 1.39 | Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock. ( Amezcua-Guerra, LM; Argueta, I; Bojalil, R; Bolaños, L; Camacho-Villegas, TA; García-Ubbelohde, WJ; Licea-Navarro, AF; Márquez-Velasco, R; Mata-González, MT; Paniagua-Solís, JF; Sánchez-Castrejón, E; Sánchez-Muñoz, F; Yee, Y, 2013) |
| " Our data showed that immunization with cardiac myosin combined with IFA led to inflammatory response in the rat myocardium." | 1.38 | [Dynamic of myocarditis development in rats after injection of cardiac myosine combined with IFA]. ( Chentsov, IuS; Gavrilova, SA; Morozova, MP; Pogodina, LS; Postnikov, AB; Zemtsova, LV, 2012) |
| "At baseline, COPD patients showed greater muscle oxidative stress and superoxide dismutase activity and circulating inflammatory cytokines than controls." | 1.38 | Muscle and blood redox status after exercise training in severe COPD patients. ( Barreiro, E; Cascante, M; Falciani, F; Gea, J; Kalko, S; Perez-Olabarría, M; Puig-Vilanova, E; Roca, J; Rodriguez, DA, 2012) |
| "Sepsis is a major health threat that remains refractory to treatment." | 1.37 | ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury. ( Goto, K; Hagiwara, S; Iwasaka, H; Koga, H; Kusaka, J; Noguchi, T; Uchida, T; Yokoi, I, 2011) |
| "Inflammation is difficult to control when it spreads throughout the body and often progresses into multiple organ dysfunction, eventually leading to death." | 1.37 | Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation. ( Hagiwara, S; Hasegawa, A; Koga, H; Kudo, K; Kusaka, J; Noguchi, T, 2011) |
| "Heat stroke is a condition characterized by high body temperature that can lead to hemorrhage and necrosis in multiple organs." | 1.37 | Danaparoid sodium attenuates the effects of heat stress. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Mizunaga, S; Nishida, T; Noguchi, T; Saikawa, T; Shingu, C; Uchida, T, 2011) |
| "Nevertheless, as heat stroke is a severe inflammatory response disease, we hypothesized that AT III would inhibit inflammation and prevent heat stress-induced acute heat stroke." | 1.36 | High-dose antithrombin III prevents heat stroke by attenuating systemic inflammation in rats. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T; Shingu, C; Uchida, T, 2010) |
| "Cotreatment of paclitaxel with TNF-alpha markedly augmented the release of TF." | 1.36 | Paclitaxel potentiates inflammatory cytokine-induced prothrombotic molecules in endothelial cells. ( Tang, X; Tesfamariam, B; Wood, SC, 2010) |
| " Oral bioavailability of P2026 was estimated from plasma concentration of diclofenac and nitrate/nitrite (NOx)." | 1.36 | Oral bioavailability, efficacy and gastric tolerability of P2026, a novel nitric oxide-releasing diclofenac in rat. ( Desai, DC; Deshattiwar, JJ; Deshmukh, NJ; Dhiman, M; Gaikwad, PP; Karwa, M; Mali, SV; Nemmani, KV; Pamidiboina, V; Pathan, AR; Satyam, A; Sharma, SD; Thanga Mariappan, T, 2010) |
| "Patients in the early phase of acute pancreatitis (AP) have reduced serum levels of arginine and citrulline." | 1.35 | Serum amino acid profile in patients with acute pancreatitis. ( Gasslander, T; Sandstrom, P; Sundqvist, T; Svanvik, J; Trulsson, L; von Dobeln, U, 2008) |
| "Inflammation is a typical reaction to infection." | 1.35 | Hyperthermia amplifies brain cytokine and reactive oxygen species response in a model of perinatal inflammation. ( Dow, KE; Flavin, MP; Wang, W, 2008) |
| "Using a carrageenan-induced thermal hyperalgesia model, we evaluated the effect of C-PC on nociception by measuring paw withdrawal latency." | 1.35 | Antiinflammatory and antihyperalgesic activity of C-phycocyanin. ( Cheng, SN; Chou, TC; Kuo, YL; Shih, CM; Wong, CS, 2009) |
| "Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental." | 1.35 | An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage. ( Barclay, D; Billiar, TR; Clermont, G; Ghuma, A; Gomez, H; Gordon, L; Hermus, L; Kim, HK; Namas, R; Ochoa, J; Peitzman, A; Pinsky, MR; Polanco, P; Puyana, JC; Rosengart, MR; Torres, A; Vodovotz, Y; Zamora, R; Zenker, S, 2009) |
| "Reduced bioavailability of endothelium-derived nitric oxide associated with reperfusion could potentially exacerbate the inflammatory response during reperfusion." | 1.34 | Inhaled nitric oxide attenuates reperfusion inflammatory responses in humans. ( Hays, S; Huda, R; Lang, JD; Mathru, M; Solanki, DR, 2007) |
| "Patients with severe sepsis develop multiple organ failure, including acute lung injury (ALI), resulting from a deregulated inflammatory response." | 1.34 | Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis. ( Antonova, G; Cannon, J; Catravas, JD; Chatterjee, A; Dimitropoulou, C; Drakopanayiotakis, F; Snead, C; Venema, RC, 2007) |
| "Metabolic syndrome is a cluster of metabolic diseases that in essence greatly promotes progression of atherosclerosis." | 1.33 | Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome. ( Haginaka, J; Kagota, S; Kunitomo, M; Nakamura, K; Yamaguchi, Y; Yoshikawa, N, 2006) |
| "Pleurisy was induced by carrageenan (1%) treatment and the parameters were analyzed 4 and 48 h after." | 1.32 | Additional evidence of acute anti-inflammatory effects of cyclosporin A in a murine model of pleurisy. ( Fröde, TS; Medeiros, YS; Monguilhott Dalmarco, E, 2004) |
| " Thus, bioavailability of NO scavengers at sites of inflammation may play an essential role in up-regulation of the catalytic activity of iNOS, by preventing the catalytic activity inhibition that is attributed to nitrosyl complex formation." | 1.32 | Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition. ( Abu-Soud, HM; Diamond, MP; Galijasevic, S; Saed, GM, 2003) |
| "Titanium has been used successfully for decades in orthopaedic and dental implants, but the mechanism mediating its biocompatible properties has not been elucidated." | 1.31 | Inhibition of inflammatory species by titanium surfaces. ( Frangos, JA; Suzuki, R, 2000) |
| "Acute lung injury is an important feature of sepsis and increased iNOS expression and NO production contribute to the pathogenesis of this syndrome." | 1.31 | Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia. ( Joseph, M; McCormack, DG; Mehta, S; Razavi, HM; Scott, JA; Wang, LF; Weicker, S, 2001) |
| "Sixty-seven patients with severe trauma were enrolled in the study." | 1.31 | Serum levels of Hsp 72 measured early after trauma correlate with survival. ( Howard, MB; Lee, H; Mackersie, RC; Morabito, D; Pittet, JF; Welch, WJ, 2002) |
| "MI/R induced severe arrhythmias, indicated by a significantly elevated arrhythmia score in the MI/R group compared with that in the sham control group." | 1.30 | Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats. ( Hock, CE; Liu, P; Nagele, R; Wong, PY, 1997) |
| "Alzheimer's disease is characterized by the development of a degenerative condition in the elderly, associated with dementia." | 1.30 | The possible role of peroxynitrite in Alzheimer's disease: a simple hypothesis that could be tested more thoroughly. ( Van Dyke, K, 1997) |
| "Cimetidine (CIM) is an H2-receptor antagonist that has been used in racehorses in an attempt to reduce the occurrence of stress-related gastric ulceration." | 1.30 | Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse. ( Dees, AA; Hunter, RP; Keowen, ML; Koch, CE; McClure, JR; Short, CR; VanSteenhouse, JL, 1999) |
| " Ten days after infection, mice treated with MMLA at dosage of 100 mg/kg, given intraperitoneally in a single dose or for 5 consecutive days, showed at histopathologic examination, a significant decrease of intensity of inflammation (scores, 0." | 1.30 | Regulation of inflammatory responses to Bordetella pertussis by N(G)-monomethyl-L-arginine in mice intranasally infected. ( Airoldi, M; Banfi, MG; Fassina, G; Osculati, A; Perversi, L; Pugliese, A; Speranza, F; Torre, D, 1999) |
| "In control specimens with no overt pulmonary disease, there was only slight staining of the alveolar septum." | 1.29 | Evidence for in vivo peroxynitrite production in human acute lung injury. ( Beckman, JS; Kelly, DR; Kooy, NW; Royall, JA; Ye, YZ, 1995) |
| "Thirty-nine critically ill trauma and septic patients were studied to determine the relationship between ." | 1.28 | Nitrogen oxide levels in patients after trauma and during sepsis. ( Billiar, TR; Cerra, FB; Curran, RD; Ochoa, JB; Peitzman, AB; Simmons, RL; Udekwu, AO, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.10) | 18.7374 |
| 1990's | 44 (16.12) | 18.2507 |
| 2000's | 104 (38.10) | 29.6817 |
| 2010's | 101 (37.00) | 24.3611 |
| 2020's | 21 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Shaker, ME | 1 |
| Hendawy, OM | 1 |
| El-Mesery, M | 1 |
| Hazem, SH | 1 |
| Miller, AL | 1 |
| Nicastro, LK | 1 |
| Bessho, S | 1 |
| Grando, K | 1 |
| White, AP | 1 |
| Zhang, Y | 8 |
| Queisser, G | 1 |
| Buttaro, BA | 1 |
| Tükel, Ç | 1 |
| Ishaq, A | 2 |
| Tchkonia, T | 1 |
| Kirkland, JL | 1 |
| Siervo, M | 2 |
| Saretzki, G | 2 |
| Attafi, IM | 1 |
| Bakheet, SA | 1 |
| Ahmad, SF | 1 |
| Belali, OM | 1 |
| Alanazi, FE | 1 |
| Aljarboa, SA | 1 |
| Al-Alallah, IA | 1 |
| Korashy, HM | 1 |
| Еlmahdy, MK | 1 |
| Abdelaziz, RR | 1 |
| Elmahdi, HS | 1 |
| Suddek, GM | 1 |
| Mota, MRL | 1 |
| do Carmo Filho, JRL | 1 |
| Martins, TV | 1 |
| Soares, DQ | 1 |
| de Sousa, MP | 1 |
| de Barros Silva, PG | 1 |
| Alves, APNN | 1 |
| Pereira, MG | 1 |
| Assreuy, AMS | 1 |
| Unger, ES | 1 |
| Grabowski, DC | 1 |
| Chen, JT | 1 |
| Berkman, LF | 1 |
| Ashoori, R | 1 |
| Samaei, MR | 1 |
| Yousefinejad, S | 1 |
| Azhdarpoor, A | 1 |
| Emadi, Z | 1 |
| Mohammadpour, A | 1 |
| Lari, AR | 1 |
| Mousavi Khaneghah, A | 1 |
| Smaali, A | 1 |
| Berkani, M | 1 |
| Benmatti, H | 1 |
| Lakhdari, N | 2 |
| Al Obaid, S | 1 |
| Alharbi, SA | 1 |
| Fakhreddine, B | 1 |
| Ines, A | 1 |
| Marouane, F | 1 |
| Rezania, S | 1 |
| Napolitano, A | 1 |
| Di Napoli, M | 1 |
| Castagliuolo, G | 1 |
| Badalamenti, N | 1 |
| Cicio, A | 1 |
| Bruno, M | 1 |
| Piacente, S | 1 |
| Maresca, V | 1 |
| Cianciullo, P | 1 |
| Capasso, L | 1 |
| Bontempo, P | 1 |
| Varcamonti, M | 1 |
| Basile, A | 1 |
| Zanfardino, A | 1 |
| Zhu, M | 1 |
| Perkins, MG | 1 |
| Lennertz, R | 1 |
| Abdulzahir, A | 1 |
| Pearce, RA | 1 |
| Awuah, KF | 1 |
| Jegede, O | 1 |
| Cousins, M | 1 |
| Renaud, M | 1 |
| Hale, B | 1 |
| Siciliano, SD | 1 |
| Cha, JS | 1 |
| Kim, YM | 1 |
| Lee, IH | 1 |
| Choi, YJ | 1 |
| Rhee, GH | 1 |
| Song, H | 1 |
| Jeon, BH | 1 |
| Lam, SS | 1 |
| Khan, MA | 1 |
| Andrew Lin, KY | 1 |
| Chen, WH | 1 |
| Park, YK | 1 |
| Soltani, NS | 1 |
| Taylor, MP | 1 |
| Wilson, SP | 1 |
| Moyo, KM | 1 |
| Choi, J | 2 |
| Chang, J | 1 |
| Soedono, S | 1 |
| Nguyet, DVH | 1 |
| Song, YR | 1 |
| Park, SJ | 1 |
| Go, GW | 1 |
| Lee, DY | 1 |
| Cho, KW | 1 |
| Rojas-Tapias, DF | 1 |
| Brown, EM | 1 |
| Temple, ER | 1 |
| Onyekaba, MA | 1 |
| Mohamed, AMT | 1 |
| Duncan, K | 1 |
| Schirmer, M | 1 |
| Walker, RL | 1 |
| Mayassi, T | 1 |
| Pierce, KA | 1 |
| Ávila-Pacheco, J | 1 |
| Clish, CB | 1 |
| Vlamakis, H | 1 |
| Xavier, RJ | 1 |
| Liu, K | 1 |
| Yang, L | 1 |
| Wang, X | 7 |
| Huang, Q | 1 |
| Tuerhong, K | 1 |
| Yang, M | 3 |
| Zhang, R | 1 |
| Li, Y | 5 |
| Yang, S | 2 |
| Bryan, NS | 2 |
| Ahmed, S | 1 |
| Lefer, DJ | 1 |
| Hord, N | 1 |
| von Schwarz, ER | 1 |
| Eglin, CM | 1 |
| Wright, J | 1 |
| Shepherd, AI | 1 |
| Massey, H | 1 |
| Hollis, S | 1 |
| Towse, J | 1 |
| Young, JS | 1 |
| Maley, MJ | 1 |
| Bailey, SJ | 1 |
| Wilkinson, C | 1 |
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| Tipton, MJ | 1 |
| Petrick, HL | 1 |
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| Brunetta, HS | 1 |
| Robinson, A | 1 |
| Kirsh, AJ | 1 |
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| van Loon, LJC | 1 |
| Chabowski, A | 1 |
| Schertzer, JD | 1 |
| Allen-Vercoe, E | 1 |
| Simpson, JA | 1 |
| Holloway, GP | 1 |
| Yang, Y | 5 |
| Li, S | 3 |
| Qu, Y | 1 |
| An, W | 1 |
| Li, Z | 3 |
| Han, Z | 2 |
| Qin, L | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
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| Dabbous, S | 1 |
| Fontaine, O | 1 |
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| Popoff, MR | 1 |
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| Gabilan, JC | 1 |
| Andremont, A | 1 |
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| Andrés, S | 1 |
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| Alonso, JM | 1 |
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| López, F | 1 |
| Jiménez, A | 1 |
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| Zhao, Y | 3 |
| Wang, J | 7 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 5 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 4 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 2 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 5 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
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| Hayton, TW | 1 |
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| Shi, J | 2 |
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| Kim, EH | 1 |
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| Venkatesh, R | 1 |
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| Saad, NES | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Dietary Nitrate on Vascular Function, Blood Pressure, the Oral Microbiome, and Biomarkers of Systemic Inflammation in Hypertensive Older Adults: a Randomized, Placebo-controlled Crossover Study[NCT04584372] | 20 participants (Actual) | Interventional | 2021-01-01 | Completed | |||
| Evaluation of Renal Sodium Excretion After Salt Loading in Heart Failure With Preserved Ejection Fraction[NCT03837470] | Early Phase 1 | 14 participants (Actual) | Interventional | 2019-05-06 | Completed | ||
| Erythrocytes and Skeletal-muscle Unsaturated and Omega-6 Fatty Acids Are Positively Correlated After Caloric Restriction and Exercise[NCT02533479] | 11 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| The Feasibility, Safety and Efficacy of Y-3 Injection Through Skull Bone Marrow Bypassing Blood-brain Barrier in the Treatment of Acute Malignant Middle Cerebral Artery Infarction(SOLUTION)[NCT05849805] | 20 participants (Anticipated) | Interventional | 2023-04-17 | Recruiting | |||
| NITRATE-OCT-CIN Trial: A Randomised, Double-blind, Placebo-controlled Study Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina (Sub-study of the NITRATE-OCT Trial)[NCT05544981] | 300 participants (Actual) | Interventional | 2016-01-02 | Completed | |||
| A Randomised, Double-blind, Placebo-controlled Study Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina[NCT02529189] | Phase 2 | 300 participants (Anticipated) | Interventional | 2015-11-30 | Active, not recruiting | ||
| A Prospective, Randomized, Double-blind, Parallel, Placebo-controlled, Multi-center Study to Investigate the Efficacy and Safety of Apomivir® in Relieving Influenza Symptoms[NCT01677689] | Phase 2 | 196 participants (Anticipated) | Interventional | 2018-09-01 | Not yet recruiting | ||
| The Effects of Mometasone on Markers of Airway Inflammation[NCT00711165] | Phase 4 | 12 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| Phenotyping Responses to Systemic Corticosteroids in the Management of Asthma Attacks (PRISMA): Clinical and Translational Correlation to Point-Of-Care Biomarkers[NCT05870215] | 62 participants (Anticipated) | Observational | 2022-09-01 | Recruiting | |||
| Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Patients With Anorexia Associated With Advanced Lung Cancer: Randomized Double Blind Clinical Trial[NCT02802540] | Phase 2/Phase 3 | 78 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | ||
| A Randomized, Double - Blind, Placebo - Controlled Trial to Investigate the Effect of Dapagliflozin on Ischemia Reperfusion Induced Endothelial Dysfunction of the Forearm Vasculature in Healthy Male Subjects[NCT05217654] | Phase 1 | 32 participants (Anticipated) | Interventional | 2022-02-18 | Recruiting | ||
| Exhaled Breath Condensate (EBC) Collection and Analysis in Mechanically Ventilated ICU Patients: Monitoring of the Influence of Various Tidal Volumes on Lung Inflammatory Biomarkers[NCT00910026] | 20 participants (Anticipated) | Interventional | 2009-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
35 reviews available for nitrates and Inflammation
| Article | Year |
|---|---|
Dietary nitrate biochemistry and physiology. An update on clinical benefits and mechanisms of action.
Topics: Cardiovascular Diseases; Humans; Inflammation; Nitrates; Nitric Oxide; Nitrites | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Electrophilic nitrated fatty acids are potential therapeutic candidates for inflammatory and fibrotic lung diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Fatty Acids; Humans; Inflammation; L | 2020 |
Hypoxia in Obesity and Diabetes: Potential Therapeutic Effects of Hyperoxia and Nitrate.
Topics: Cell Hypoxia; Diabetes Mellitus, Type 2; Hyperoxia; Inflammation; Nitrates; Obesity; Oxidative Stres | 2017 |
Heart Failure with Preserved Ejection Fraction.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Agents; D | 2018 |
Diminishing Inflammation by Reducing Oxidant Generation: Nitrated Fatty Acid-Mediated Inactivation of Xanthine Oxidoreductase.
Topics: Fatty Acids; Humans; Inflammation; Nitrates; Oxidants; Xanthine Dehydrogenase | 2019 |
Red meat, dietary heme iron, and risk of type 2 diabetes: the involvement of advanced lipoxidation endproducts.
Topics: Animals; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Female; Ferritins; Food Handling; Glycatio | 2013 |
Inflammatory and oxidative and nitrosative stress cascades as new drug targets in myalgic encephalomyelitis and chronic fatigue syndrome.
Topics: Animals; Fatigue Syndrome, Chronic; Humans; Inflammation; Nitrates; Oxidative Stress; Risk Factors | 2013 |
Childhood asthma biomarkers: present knowledge and future steps.
Topics: Aldehydes; Asthma; Biomarkers; Breath Tests; Child; Dinoprost; Humans; Hydrogen Peroxide; Hydrogen-I | 2015 |
Nitrate/Nitrite as Critical Mediators to Limit Oxidative Injury and Inflammation.
Topics: Animals; Humans; Inflammation; Nitrates; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidation-Reduc | 2015 |
Dietary inorganic nitrate: From villain to hero in metabolic disease?
Topics: Adipose Tissue; Biological Availability; Diabetes Mellitus, Type 2; Diet; Heart; Humans; Hypertensio | 2016 |
Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation.
Topics: Animals; Humans; Inflammation; Neuroprotective Agents; Neurotoxins; Nitrates; Oxidative Stress; Stro | 2016 |
Ischemic Heart Disease in HIV: An In-depth Look at Cardiovascular Risk.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-HIV Agents; Anticholesteremic Agents; Anticoagulants; | 2016 |
[New mechanisms by which physical exercise improves insulin resistance in the skeletal muscle].
Topics: Exercise; Glucose; Humans; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Mu | 2009 |
Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease.
Topics: Amino Acids; Arthritis, Rheumatoid; Autoantibodies; Autoimmunity; Biomarkers; Epitopes; Humans; Infl | 2011 |
The role of mitochondrial nitric oxide synthase in inflammation and septic shock.
Topics: Animals; Humans; Inflammation; Lipopolysaccharides; Mitochondria; Nitrates; Nitric Oxide; Nitric Oxi | 2002 |
Roles of nitric oxide and superoxide in inflammation.
Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte | 2003 |
Analysis of nitrite and nitrate in the study of inflammation.
Topics: Animals; Calibration; Cells, Cultured; Cytokines; Electrophoresis, Capillary; Fibroblasts; Gene Expr | 2003 |
Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis.
Topics: Animals; Carnitine O-Palmitoyltransferase; Inflammation; Myocardium; Nitrates; Oxidation-Reduction; | 2003 |
NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response?
Topics: Animals; Free Radicals; Humans; Inflammation; Models, Biological; Nitrates; Nitric Oxide; Nitrogen D | 2003 |
Nitric oxide and inflammation.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Drug Evaluation | 2006 |
NF-kappaB, inflammation and pancreatic carcinogenesis: NF-kappaB as a chemoprevention target (review).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Cell Pr | 2006 |
Potential genotoxicity of chronically elevated nitric oxide: a review.
Topics: Animals; Cell Transformation, Neoplastic; Deamination; DNA Adducts; DNA Damage; Humans; Hydroxyl Rad | 1995 |
The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.
Topics: Animals; Humans; Hydroxyl Radical; Inflammation; Ischemia; Nitrates; Nitric Oxide; Nitric Oxide Synt | 1996 |
Role of poly(ADP-ribose) synthetase activation in the suppression of cellular energetics in response to nitric oxide and peroxynitrite.
Topics: Animals; Diabetes Mellitus; DNA Damage; Energy Metabolism; Enzyme Activation; Humans; Hydroxyl Radic | 1997 |
DNA damage induced by peroxynitrite: subsequent biological effects.
Topics: Animals; Apoptosis; Cell Transformation, Neoplastic; DNA; DNA Damage; Guanine; Humans; Inflammation; | 1997 |
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion.
Topics: Animals; Cell Death; DNA Damage; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; | 1998 |
Nitric oxide and oxygen radicals in infection, inflammation, and cancer.
Topics: Animals; Bacterial Infections; Free Radicals; Humans; Infections; Inflammation; Mice; Neoplasms; Nit | 1998 |
Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice.
Topics: Animals; Arthritis; Autoimmune Diseases; Autoimmunity; Disease Models, Animal; Humans; Inflammation; | 1998 |
The nonspecific inflammatory response to injury.
Topics: Cell Adhesion Molecules; Cytokines; Endothelium, Vascular; Free Radical Scavengers; Humans; Inflamma | 1998 |
Demyelination: the role of reactive oxygen and nitrogen species.
Topics: Animals; Antioxidants; Demyelinating Diseases; Humans; Inflammation; Lipid Peroxidation; Nervous Sys | 1999 |
Nitric Oxide. III. A molecular prelude to intestinal inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Female; Humans; Inflammation; Intestin | 1999 |
Biological aspects of reactive nitrogen species.
Topics: Animals; Apoptosis; Inflammation; Lipoproteins; Membranes; Nitrates; Nitric Oxide; Nitric Oxide Dono | 1999 |
Neurodegenerative disorders: the role of peroxynitrite.
Topics: Alzheimer Disease; Animals; Central Nervous System; Humans; Inflammation; Motor Neuron Disease; Mult | 1999 |
Implications of inducible nitric oxide synthase expression and enzyme activity.
Topics: Apoptosis; Humans; Inflammation; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Synthase; | 2000 |
13 trials available for nitrates and Inflammation
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study.
Topics: Aged; Aging; Beta vulgaris; Biomarkers; Blood Platelets; Blood Pressure; Cardiovascular Diseases; CD | 2017 |
Topics: Adult; Aged; Animals; Astrocytes; Bariatric Surgery; Beta vulgaris; Bioreactors; Biotechnology; Bloo | 2018 |
Effects of docosahexaenoic supplementation and in vitro vitamin C on the oxidative and inflammatory neutrophil response to activation.
Topics: Ascorbic Acid; Catalase; Dietary Supplements; Docosahexaenoic Acids; Erythrocytes; Gene Expression R | 2015 |
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat | 2016 |
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat | 2016 |
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat | 2016 |
Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study.
Topics: Adolescent; Adult; Angina, Stable; Beta vulgaris; Blood Platelets; Blood Vessel Prosthesis Implantat | 2016 |
Comparison of the anti-inflammatory effects of extra-fine hydrofluoroalkane-beclomethasone vs fluticasone dry powder inhaler on exhaled inflammatory markers in childhood asthma.
Topics: Administration, Inhalation; Androstadienes; Anti-Inflammatory Agents; Asthma; Beclomethasone; Biomar | 2008 |
Time-dependent effects of inhaled corticosteroids on lung function, bronchial hyperresponsiveness, and airway inflammation in asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Allergic Agents; Anti-Inflammatory | 2009 |
Measurements of canine aqueous humor inflammatory mediators and the effect of carprofen following anterior chamber paracentesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Carbazoles; Cyclooxygenase 2; Dinop | 2011 |
Effects of phospholipid-coated extracorporeal circuits on clinical outcome parameters and systemic inflammatory response in coronary artery bypass graft patients.
Topics: Aged; Analysis of Variance; Biomarkers; Coated Materials, Biocompatible; Coronary Artery Bypass; Cre | 2002 |
Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment.
Topics: Adult; Aged; Anti-Inflammatory Agents; Azithromycin; Biomarkers; Blood Cell Count; C-Reactive Protei | 2005 |
Inflammatory response in children after laparoscopic vs open Nissen fundoplication: randomized controlled trial.
Topics: Child; Cytokines; Fundoplication; Genes, MHC Class II; Humans; Inflammation; Interleukin 1 Receptor | 2005 |
Effect of doxazosin on C-reactive protein plasma levels and on nitric oxide in patients with hypertension.
Topics: Adult; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Doxazosin; Female; H | 2006 |
Relation of pro- and anti-inflammatory cytokines and the production of nitric oxide in patients receiving high-dose immunotherapy with interleukin-2.
Topics: Adult; Antigens, CD; Biomarkers; Cytokines; Female; Humans; Immunotherapy; Inflammation; Infusions, | 2000 |
226 other studies available for nitrates and Inflammation
| Article | Year |
|---|---|
The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice.
Topics: Aldehydes; Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokine Release Syndrom | 2022 |
Nitrate Is an Environmental Cue in the Gut for Salmonella enterica Serovar Typhimurium Biofilm Dispersal through Curli Repression and Flagellum Activation via Cyclic-di-GMP Signaling.
Topics: Bacterial Proteins; Biofilms; Cues; Cyclic GMP; Flagella; Gene Expression Regulation, Bacterial; Hum | 2021 |
Palmitate induces DNA damage and senescence in human adipocytes in vitro that can be alleviated by oleic acid but not inorganic nitrate.
Topics: Adipocytes; DNA Damage; Humans; Hypertrophy; Inflammation; Nitrates; Oleic Acid; Palmitates | 2022 |
Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways.
Topics: Animals; Apoptosis; Inflammation; Lead; Lung; Male; NF-kappa B; Nitrates; Pneumonia; Rats; Rats, Wis | 2022 |
Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study.
Topics: Agmatine; Animals; Anti-Asthmatic Agents; Beclomethasone; Cytokines; Disease Models, Animal; Inflamm | 2022 |
Polysaccharide extract of Caesalpinia ferrea (Mart) pods attenuates inflammation and enhances the proliferative phase of rat cutaneous wounds.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Caesalpinia; Inflammation; Malondialdehyde; Nitrates; | 2022 |
Topics: Activities of Daily Living; Adult; Air Pollution, Indoor; Animals; Anti-Bacterial Agents; Anti-Infec | 2021 |
Inflammation-associated nitrate facilitates ectopic colonization of oral bacterium Veillonella parvula in the intestine.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Carbon; Inflammation; Inflammatory Bowel Diseases; Int | 2022 |
Electroacupuncture regulates macrophage, neutrophil, and oral microbiota to alleviate alveolar bone loss and inflammation in experimental ligature-induced periodontitis.
Topics: Alveolar Bone Loss; Animals; Cytokines; Electroacupuncture; Inflammation; Macrophages; Mice; Microbi | 2023 |
Plasma biomarkers of endothelial function, inflammation and oxidative stress in individuals with non-freezing cold injury.
Topics: Biomarkers; Cold Injury; Cold Temperature; Endothelin-1; Humans; Inflammation; Interleukin-10; Inter | 2023 |
Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.
Topics: Animals; Diet, High-Fat; Dysbiosis; Fibrosis; Gastrointestinal Microbiome; Glucose Intolerance; Hear | 2023 |
Nitrate partially inhibits lipopolysaccharide-induced inflammation by maintaining mitochondrial function.
Topics: Animals; Benzimidazoles; Carbocyanines; Fluorescent Dyes; Gene Expression Regulation; Inflammation; | 2020 |
Immune-Inflammatory, Metabolic, Oxidative, and Nitrosative Stress Biomarkers Predict Acute Ischemic Stroke and Short-Term Outcome.
Topics: Aged; Biomarkers; Blood Glucose; Blood Sedimentation; C-Reactive Protein; Case-Control Studies; Chol | 2020 |
A designed whole-cell biosensor for live diagnosis of gut inflammation through nitrate sensing.
Topics: Animals; Bacterial Proteins; Biosensing Techniques; DNA-Binding Proteins; Escherichia coli; Escheric | 2020 |
Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure.
Topics: Animals; Blood Pressure; Body Weight; Cardiomyopathy, Dilated; Cationic Amino Acid Transporter 1; En | 2020 |
Electrochemical evidence of nitrate release from the nitrooxy compound 4-((nitrooxy) methyl)-3-nitrobenzoic acid and its antinociceptive and anti-inflammatory activities in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Elect | 2021 |
WAT do you NO? Addressing obesity-related cardiometabolic dysfunction.
Topics: Adipose Tissue; Cardiovascular Diseases; Diet, High-Fat; Glucose Intolerance; Humans; Inflammation; | 2021 |
Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension | 2021 |
High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine
Topics: Animals; Cell Hypoxia; Choline; Colon; Diet, High-Fat; Energy Metabolism; Epithelial Cells; Escheric | 2021 |
Potential anti-inflammatory effect of LQFM-021 in carrageenan-induced inflammation: The role of nitric oxide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2 In | 2017 |
Beetroot and Sodium Nitrate Ameliorate Cardiometabolic Changes in Diet-Induced Obese Hypertensive Rats.
Topics: Animals; Beta vulgaris; Betacyanins; Body Composition; Cardiovascular Diseases; Diet, High-Fat; Gene | 2017 |
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alph | 2018 |
Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift.
Topics: Animals; Anti-Inflammatory Agents; Cell Respiration; Fibroblasts; Humans; Hypoxia-Inducible Factor 1 | 2017 |
Effects of long-term nitrate supplementation on carbohydrate metabolism, lipid profiles, oxidative stress, and inflammation in male obese type 2 diabetic rats.
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, | 2018 |
Oxidative stress, NOx/l-arginine ratio and glutathione/glutathione S-transferase ratio as predictors of 'sterile inflammation' in patients with alcoholic cirrhosis and hepatorenal syndrome type II.
Topics: Adult; Aged; Arginine; Biomarkers; Female; Glutathione; Glutathione Transferase; Hepatorenal Syndrom | 2018 |
Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis.
Topics: Animals; Catalase; Cognition Disorders; Cytokines; Dimethyl Fumarate; Disease Models, Animal; Explor | 2018 |
Can nonalcoholic beer, silicon and hops reduce the brain damage and behavioral changes induced by aluminum nitrate in young male Wistar rats?
Topics: Acetylcholinesterase; Aluminum Compounds; Animals; Antioxidants; Behavior, Animal; Beverages; Brain; | 2018 |
Pomegranate prevents binge alcohol-induced gut leakiness and hepatic inflammation by suppressing oxidative and nitrative stress.
Topics: Animals; Antioxidants; Apoptosis; Binge Drinking; Female; Inflammation; Intestinal Mucosa; Intestine | 2018 |
Oxidative Imbalance, Nitrative Stress, and Inflammation in C6 Glial Cells Exposed to Hexacosanoic Acid: Protective Effect of N-acetyl-L-cysteine, Trolox, and Rosuvastatin.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Chromans; Cytoplasmic Vesicles; DNA | 2018 |
Royal Jelly Abrogates Cadmium-Induced Oxidative Challenge in Mouse Testes: Involvement of the Nrf2 Pathway.
Topics: Animals; Apoptosis; Cadmium; Fatty Acids; Follicle Stimulating Hormone; Glutathione; Inflammation; L | 2018 |
Inorganic nitrate prevents the loss of tight junction proteins and modulates inflammatory events induced by broad-spectrum antibiotics: A role for intestinal microbiota?
Topics: Animals; Anti-Bacterial Agents; Base Sequence; Cecum; Claudin-5; Dysbiosis; Feces; Gastric Mucosa; G | 2019 |
Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.
Topics: Adolescent; Adult; Animals; Asthma; Disease Models, Animal; Eflornithine; Female; Humans; Hypersensi | 2013 |
Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock.
Topics: Animals; Biomarkers; Disease Models, Animal; Humans; Inflammation; Interleukin-10; Interleukin-6; Li | 2013 |
Salmonella uses energy taxis to benefit from intestinal inflammation.
Topics: Animals; Bacterial Proteins; Carrier Proteins; Chemotaxis; Colitis; Electron Transport; Energy Metab | 2013 |
Markers of airway inflammation in the exhaled breath condensate of preschool wheezers.
Topics: Biomarkers; Breath Tests; Child, Preschool; Dinoprost; Exhalation; Female; Humans; Infant; Inflammat | 2013 |
Smoking attenuates the age-related decrease in IgE levels and maintains eosinophilic inflammation.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Asthma; Cross-Sectional Studies; Cytokines; | 2013 |
The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.
Topics: Animals; Body Weight; C-Reactive Protein; Caspase 3; Chemokine CCL2; Cysteine; Cytochromes c; Diabet | 2013 |
Croton antisyphiliticus Mart. attenuates the inflammatory response to carrageenan-induced pleurisy in mice.
Topics: Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Carrageenan; Croton; Disease Models, Animal; | 2014 |
Systemic administration of Rosmarinus officinalis attenuates the inflammatory response induced by carrageenan in the mouse model of pleurisy.
Topics: Abietanes; Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Carrageenan; Cinnamates; Cytokine | 2013 |
Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diet; Diet, High-Fat; Gene Expressio | 2014 |
Sulfated-polysaccharide fraction extracted from red algae Gracilaria birdiae ameliorates trinitrobenzenesulfonic acid-induced colitis in rats.
Topics: Animals; Colitis; Colon; Cytokines; Dexamethasone; Glutathione; Gracilaria; Inflammation; Lipid Pero | 2014 |
In vitro inflammatory/anti-inflammatory effects of nitrate esters of purines.
Topics: Anti-Inflammatory Agents; Caspase 1; Cell Line; Cell Survival; Esters; Humans; Inflammation; Interle | 2014 |
Anti-inflammatory effects of Allium schoenoprasum L. leaves.
Topics: Animals; Anti-Inflammatory Agents; Chive; Inflammation; Leukocytes; Male; Nitrates; Nitrites; Oxidat | 2014 |
Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion.
Topics: Animals; Apoptosis; I-kappa B Proteins; Inflammation; Interleukin-6; Ischemia; Jejunum; JNK Mitogen- | 2014 |
5-Aminosalicylic acid attenuates allergen-induced airway inflammation and oxidative stress in asthma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Inflammation | 2014 |
Indium and indium tin oxide induce endoplasmic reticulum stress and oxidative stress in zebrafish (Danio rerio).
Topics: Animals; Apoptosis; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Pr | 2014 |
Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice.
Topics: Aging; Animals; Cytokines; Dietary Supplements; Drug Evaluation, Preclinical; Inflammation; Male; Mi | 2015 |
Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy.
Topics: Adolescent; Adult; Aged; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Diabetes Mellitus, | 2015 |
Alpha-lipoic acid prevents endotoxic shock and multiple organ dysfunction syndrome induced by endotoxemia in rats.
Topics: Animals; Antioxidants; Antithrombins; Aorta; Caspase 3; Disulfides; Endotoxemia; Enzyme Activation; | 2015 |
Anti-inflammatory effect of water-soluble complex of 1'-acetoxychavicol acetate with highly branched β-1,3-glucan on contact dermatitis.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Alcohols; beta-Glucans; Cell Line; Cytokines; Dermatitis, | 2015 |
The nitric oxide donor cis-[Ru(bpy)2(SO3)NO](PF6) increases gastric mucosa protection in mice--involvement of the soluble guanylate cyclase/K(ATP) pathway.
Topics: 2,2'-Dipyridyl; Animals; Cytokines; Ethanol; Gastric Mucosa; Guanylate Cyclase; Inflammation; KATP C | 2015 |
Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride.
Topics: Animals; Cell Line; Glutathione; Hydrogen-Ion Concentration; Inflammation; Kinetics; Linoleic Acids, | 2015 |
Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Body Mass Index; Colorectal Neoplasms; Cyclooxygenase 2 Inh | 2016 |
Biomarkers of oxidative-stress and inflammation in exhaled breath condensate from hospital cleaners.
Topics: Adult; Aldehydes; Ammonium Compounds; Biomarkers; Breath Tests; C-Reactive Protein; Cross-Sectional | 2016 |
Comment on Lee et al. Diabetes 2015;64:2836-2846. Comment on Roberts et al. Diabetes 2015;64:471-484.
Topics: Adipose Tissue, White; Animals; Cell Polarity; Endothelium, Vascular; Inflammation; Macrophages; Mal | 2016 |
Response to Comment on Lee et al. Diabetes 2015;64:2836-2846. Comment on Roberts et al. Diabetes 2015;64:471-484.
Topics: Adipose Tissue, White; Animals; Cell Polarity; Endothelium, Vascular; Inflammation; Macrophages; Mal | 2016 |
Nitrated Fatty Acids Reverse Cigarette Smoke-Induced Alveolar Macrophage Activation and Inhibit Protease Activity via Electrophilic S-Alkylation.
Topics: Alkylation; Animals; Anti-Inflammatory Agents; Biomarkers; Cathepsins; Down-Regulation; Fatty Acids; | 2016 |
An exaggerated blood pressure response to exercise is associated with nitric oxide bioavailability and inflammatory markers in normotensive females.
Topics: Adult; Biomarkers; Blood Pressure; Exercise; Exercise Test; Female; Humans; Inflammation; Middle Age | 2016 |
Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case.
Topics: Arginine; Child; Cystic Fibrosis; Diet; Exhalation; Humans; Inflammation; Iron; Male; Nitrates; Nitr | 2016 |
Magnetic resonance imaging biomarkers of exercise-induced improvement of oxidative stress and inflammation in the brain of old high-fat-fed ApoE
Topics: Aging; Animals; Aorta; Apolipoproteins E; Biomarkers; Brain; Catalase; Cholesterol; Diet, High-Fat; | 2016 |
Inorganic Nitrate Supplementation in Young and Old Obese Adults Does Not Affect Acute Glucose and Insulin Responses but Lowers Oxidative Stress.
Topics: Adolescent; Adult; Aged; Aging; Biomarkers; Blood Glucose; Female; Humans; Inflammation; Insulin; Ma | 2016 |
Anti-inflammatory effect of selenium nanoparticles on the inflammation induced in irradiated rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Dinoprostone; Inflammation; Leukocyte Count; Male; Na | 2017 |
Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome.
Topics: Diet; Gastrointestinal Tract; Humans; Inflammation; Microbiota; Models, Biological; Nitrates; Polyph | 2016 |
Silicic Acid and Beer Consumption Reverses the Metal Imbalance and the Prooxidant Status Induced by Aluminum Nitrate in Mouse Brain.
Topics: Aluminum; Aluminum Compounds; Animals; Beer; Brain; Cations; Copper; Gene Expression; Inflammation; | 2017 |
Inhibition of matrix metalloproteinase-9 by a barbiturate-nitrate hybrid ameliorates dextran sulphate sodium-induced colitis: effect on inflammation-related genes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Colitis; Dextran Sulfate; Disease Mo | 2017 |
Plasma levels of nitrite/nitrate and inflammation markers in elderly individuals.
Topics: Aged; Aged, 80 and over; C-Reactive Protein; Female; Humans; Inflammation; Inflammation Mediators; M | 2008 |
Hyperthermia amplifies brain cytokine and reactive oxygen species response in a model of perinatal inflammation.
Topics: Animals; Brain; Cytokines; Disease Models, Animal; Female; Hyperthermia, Induced; Hypoxia; Inflammat | 2008 |
Nitric oxide metabolites (nitrite and nitrate) in young patients with recent acute myocardial infarction.
Topics: Adult; Female; Humans; Inflammation; Male; Myocardial Infarction; Nitrates; Nitric Oxide; Nitrites; | 2008 |
An alpha4beta1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice.
Topics: Animals; Biological Availability; Biomarkers; Bronchoalveolar Lavage; Dipeptides; Exhalation; Goblet | 2009 |
Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice.
Topics: Animals; Arginine; Colon; Colonic Neoplasms; DNA-Binding Proteins; Enzyme Inhibitors; Helicobacter h | 2009 |
Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide.
Topics: Amidines; Animals; Benzylamines; E-Selectin; Enzyme Inhibitors; Epithelial Cells; Hindlimb; Inflamma | 2009 |
Antiinflammatory and antihyperalgesic activity of C-phycocyanin.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Dinoprostone; Disease | 2009 |
Cardiovascular prevention by dietary nitrate and nitrite.
Topics: Animals; Anti-Inflammatory Agents; Cardiovascular Diseases; Diet; Endothelium, Vascular; Humans; Hyp | 2009 |
Pre-emptive anti-hyperalgesic effect of electroacupuncture in carrageenan-induced inflammation: role of nitric oxide.
Topics: Animals; Carrageenan; Electroacupuncture; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hot | 2009 |
Inflammation but not endothelial dysfunction is associated with the severity of coronary artery disease in dyslipidemic subjects.
Topics: Adult; Aged; C-Reactive Protein; Coronary Artery Disease; Dyslipidemias; Endothelium, Vascular; Huma | 2009 |
Effects of dietary glycine supplementation and fish meal on inflammatory responses in broiler chicks.
Topics: Animals; Ceruloplasmin; Chickens; Diet; Fish Products; Glycine; Inflammation; Interleukin-1beta; Mal | 2009 |
Effects of apple juice on risk factors of lipid profile, inflammation and coagulation, endothelial markers and atherosclerotic lesions in high cholesterolemic rabbits.
Topics: Animals; Atherosclerosis; Beverages; C-Reactive Protein; Cholesterol; Fibrinogen; Inflammation; Lipi | 2009 |
[Inflammation markers in the exhaled air of patients with bronchiectasis unassociated with cystic fibrosis].
Topics: Biomarkers; Breath Tests; Bronchiectasis; C-Reactive Protein; Cystic Fibrosis; Dinoprost; Female; Hu | 2009 |
Rosiglitazone reduces blood pressure in female Dahl salt-sensitive rats.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; Chemokine CCL2; Choles | 2010 |
Prostaglandin E2 and cysteinyl leukotriene concentrations in sputum: association with asthma severity and eosinophilic inflammation.
Topics: Adult; Aged; Asthma; Biomarkers; Cysteine; Dinoprostone; Disease Progression; Eosinophils; Female; H | 2010 |
An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.
Topics: Animals; Disease Models, Animal; Female; Humans; Inflammation; Male; Middle Aged; Nitrates; Nitrites | 2009 |
High-dose antithrombin III prevents heat stroke by attenuating systemic inflammation in rats.
Topics: Animals; Anticoagulants; Antithrombin III; Cytokines; Heat Stroke; HMGB1 Protein; Inflammation; Inte | 2010 |
Redox balance and cellular inflammation in the diaphragm, limb muscles, and lungs of mechanically ventilated rats.
Topics: Animals; Antioxidants; Biomarkers; Catalase; Diaphragm; Immunohistochemistry; Inflammation; Lung; Ma | 2010 |
Paclitaxel potentiates inflammatory cytokine-induced prothrombotic molecules in endothelial cells.
Topics: Cells, Cultured; Cytokines; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Gene Expressi | 2010 |
Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Bifla | 2010 |
Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Cell Line; Disease Models, An | 2011 |
Impact of serum estradiol on postprandial lipemia, oxidative stress, and inflammation across a single menstrual cycle.
Topics: Adolescent; Adult; Analysis of Variance; Antioxidants; Area Under Curve; C-Reactive Protein; Chroman | 2010 |
Oral bioavailability, efficacy and gastric tolerability of P2026, a novel nitric oxide-releasing diclofenac in rat.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bio | 2010 |
ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury.
Topics: Acute Lung Injury; Animals; Antioxidants; Cell Line; Chemical and Drug Induced Liver Injury; Disease | 2011 |
Insulin treatment of diabetic rats reduces cardiac function in a lipopolysaccharide-induced systemic inflammation model.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Heart Diseases; Hea | 2011 |
Danaparoid sodium attenuates the effects of heat stress.
Topics: Acute Disease; Animals; Anticoagulants; Antithrombin III; Chondroitin Sulfates; Cytokines; Dermatan | 2011 |
Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats.
Topics: Adipose Tissue; Animals; Blood; Blood Pressure; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi | 2010 |
Biocompatibility of accelerated mineral trioxide aggregate in a rat model.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Calcium Chloride; Calcium Compounds; Coloring | 2010 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, A | 2010 |
The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation.
Topics: Aging; Animals; Blotting, Western; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Endotoxem | 2011 |
Appetite-regulating hormones in chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Appetite; Body Mass Index; Cross-Sectional Studies; Enzyme-Linked Immunosor | 2011 |
Nitric oxide production is increased in severely obese children and related to markers of oxidative stress and inflammation.
Topics: Adolescent; Biomarkers; Child; Female; Humans; Inflammation; Insulin Resistance; Male; Nitrates; Nit | 2011 |
High fat feeding impairs endothelin-1 mediated vasoconstriction through increased iNOS-derived nitric oxide.
Topics: Adiposity; Animals; Blood Pressure; Dietary Fats; Endothelin-1; Feeding Behavior; In Vitro Technique | 2011 |
A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks.
Topics: Animals; Cluster Analysis; Inflammation; Interleukin-10; Interleukin-6; Male; Mice; Mice, Inbred C57 | 2011 |
Protective effects of tryptophan on neuro-inflammation in rats after administering lipopolysaccharide.
Topics: Animals; Antioxidants; Cerebral Cortex; Drug Interactions; Female; Free Radical Scavengers; Hippocam | 2011 |
Tyrosine nitration limits stretch-induced CD40 expression and disconnects CD40 signaling in human endothelial cells.
Topics: CD40 Antigens; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Hemodynamics; Humans; | 2011 |
Effects of combined levosimendan and vasopressin on pulmonary function in porcine septic shock.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Drug Therapy, Combination; Female; Hemodynamics; HMG- | 2012 |
Muscle and blood redox status after exercise training in severe COPD patients.
Topics: Aged; Case-Control Studies; Catalase; Cytokines; Exercise; Female; Glutathione; Humans; Inflammation | 2012 |
Decreased leukocyte recruitment by inorganic nitrate and nitrite in microvascular inflammation and NSAID-induced intestinal injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Movement; Cells, Cultured; Che | 2012 |
Appropriate dose of parenteral arginine enhances immunity of peripheral blood cells and splenocytes in rats with subacute peritonitis.
Topics: Animals; Arginine; Chronic Disease; Concanavalin A; Cytokines; Deficiency Diseases; Dietary Suppleme | 2012 |
Prevention of bleomycin-induced lung fibrosis in mice by a novel approach of parallel inhibition of cyclooxygenase and nitric-oxide donation using NCX 466, a prototype cyclooxygenase inhibitor and nitric-oxide donor.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomyc | 2012 |
Amelioration of renal injury and oxidative stress by the nNOS inhibitor L-VNIO in the salt-sensitive mRen2.Lewis congenic rat.
Topics: Animals; Biopterins; Blood Pressure; Female; Gene Expression Regulation; Hypertension; Inflammation; | 2012 |
Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Female; Fibrin Fibrinogen Degradation Products; Fibri | 2012 |
Beneficial effects of the ethanol extract of Caesalpinia pyramidalis on the inflammatory response and abdominal hyperalgesia in rats with acute pancreatitis.
Topics: Abdominal Pain; Acute Disease; Amylases; Analgesics; Animals; Anti-Inflammatory Agents; Brazil; Caes | 2012 |
[Dynamic of myocarditis development in rats after injection of cardiac myosine combined with IFA].
Topics: Animals; Apoptosis; Autoimmune Diseases; Cardiac Myosins; Cytokines; Freund's Adjuvant; Inflammation | 2012 |
Association between exhaled breath condensate nitrate + nitrite levels with ambient coarse particle exposure in subjects with airways disease.
Topics: Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Asthma; Biomarkers; Cities; Environmenta | 2012 |
Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.
Topics: Adamantane; Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus, Experimental; Dipeptidyl-Pept | 2012 |
Anti-inflammatory effect of certain dihydroxy flavones and the mechanisms involved.
Topics: Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines | 2012 |
Stevioside protects LPS-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cell Count; Cycl | 2013 |
Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats.
Topics: Animals; Arginine; Dietary Carbohydrates; Energy Metabolism; Humans; Inflammation; Liver; Male; Mito | 2013 |
INF-β1b therapy modulates L-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis.
Topics: Adult; Arginase; Arginine; Biomarkers; Drug Monitoring; Female; Follow-Up Studies; Humans; Inflammat | 2012 |
Inhibitory effect of anethole in nonimmune acute inflammation.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Anti-Inflammatory Agents; Carrageenan; Croton Oil; Dino | 2013 |
Inhibition of hypochlorous acid-induced cellular toxicity by nitrite.
Topics: Adenosine Triphosphate; Cell Line; Cell Survival; Chondrocytes; Glutathione; Humans; Hypochlorous Ac | 2002 |
Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis.
Topics: Adult; Biomarkers; Central Nervous System; Female; Humans; Inflammation; Male; Middle Aged; Multiple | 2003 |
Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure.
Topics: Adolescent; Age Factors; Analysis of Variance; Antipyrine; Case-Control Studies; Child; Child, Presc | 2003 |
Gamma-tocopherol, but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Carrageenan; Chromans; Dinoprostone; Dose-Response Relation | 2003 |
Differential mononuclear cell activity and endothelial inflammation in coronary artery disease and cardiac syndrome X.
Topics: Analysis of Variance; Biomarkers; Case-Control Studies; Cell Adhesion Molecules; Chi-Square Distribu | 2003 |
Nicotinamide increases systemic vascular resistance in ovine endotoxemia.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Disease Mode | 2003 |
[A study on cytokine levels and nitric oxide content in rabbit aqueous humor after lens extraction and intraocular lens implantation].
Topics: Animals; Aqueous Humor; Cataract Extraction; Cytokines; Female; Inflammation; Interleukin-2; Lens Ca | 2003 |
Cytokine induction of prolactin receptors mediates prolactin inhibition of nitric oxide synthesis in pulmonary fibroblasts.
Topics: Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Cytokines; Dimerization; Dose-Respo | 2003 |
Nitric oxide metabolites, eosinophils, and eosinophilic cationic protein in patients with asthma: sputum versus blood.
Topics: Adult; Area Under Curve; Asthma; Blood Proteins; Eosinophil Granule Proteins; Eosinophils; Female; F | 2003 |
INHIBITORY SYNAPSES AND INFLAMMATION.
Topics: Brain; Cats; Cerebral Cortex; Electrophysiology; Inflammation; Injections, Intravenous; Motor Neuron | 1965 |
Protective effects of anthocyanins from blackberry in a rat model of acute lung inflammation.
Topics: Acute Disease; Animals; Anthocyanins; Carrageenan; Dinoprostone; Exudates and Transudates; Fruit; Gl | 2003 |
Sputum peroxynitrite inhibitory activity is stimulating.
Topics: Administration, Inhalation; Antioxidants; Asthma; Beclomethasone; Glucocorticoids; Humans; Inflammat | 2003 |
Neutrophil myeloperoxidase chlorinates and nitrates soy isoflavones and enhances their antioxidant properties.
Topics: Antioxidants; Cell Differentiation; Cells, Cultured; Chlorine; Chromatography, High Pressure Liquid; | 2003 |
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Es | 2003 |
Dynamics of protein nitration in cells and mitochondria.
Topics: Cell Hypoxia; Cell Line; Cells; Humans; Inflammation; Mitochondria; Nitrates; Oxygen; Oxygen Consump | 2004 |
Successful treatment of refractory vasospastic angina with corticosteroids: coronary arterial hyperactivity caused by local inflammation?
Topics: Adrenal Cortex Hormones; Adult; Angina Pectoris; Anti-Inflammatory Agents; Asthma; Calcium Channel B | 2004 |
Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats.
Topics: Animals; Blood Pressure; Cholesterol; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydro | 2004 |
Enhanced inflammatory responses in alpha-tocopherol transfer protein null mice.
Topics: Animals; Carrier Proteins; Female; Gene Deletion; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; In | 2004 |
Additional evidence of acute anti-inflammatory effects of cyclosporin A in a murine model of pleurisy.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chemotaxis, Leukocyte; Cyclosporine; Disease Models, | 2004 |
Calpain inhibitors improve myocardial dysfunction and inflammation induced by endotoxin in rats.
Topics: Animals; Cardiomyopathies; Endotoxins; Glycoproteins; Heart; In Vitro Techniques; Inflammation; Inje | 2004 |
Nuclear factor-kappaB regulates inflammatory cell apoptosis and phagocytosis in rat carrageenin-sponge implant model.
Topics: Animals; Apoptosis; Blotting, Western; Carrageenan; Cell Movement; Disease Models, Animal; Enzyme-Li | 2004 |
Peroxynitrite, a product between nitric oxide and superoxide anion, plays a cytotoxic role in the development of post-bypass systemic inflammatory response.
Topics: Animals; Cardiopulmonary Bypass; Free Radical Scavengers; Inflammation; Interleukin-6; Interleukin-8 | 2004 |
Inhibitory effects of proanthocyanidins from Ribes nigrum leaves on carrageenin acute inflammatory reactions induced in rats.
Topics: Animals; Carrageenan; Cytokines; Disease Models, Animal; Edema; Inflammation; Male; Nitrates; Nitrit | 2004 |
Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experiment | 2005 |
Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.
Topics: Animals; Aorta; Blood Pressure; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Chromones; Cy | 2005 |
Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production.
Topics: Algorithms; Animals; Blotting, Northern; Blotting, Western; Cyclooxygenase 2; Cytokines; Cytosol; En | 2005 |
Local nitric oxide levels reflect the degree of allergic airway inflammation after segmental allergen challenge in asthmatics.
Topics: Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Case-Control Studies; Humans; Hyp | 2005 |
The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation.
Topics: Animals; Brain; Central Nervous System; CREB-Binding Protein; Cytochrome P-450 Enzyme System; Diseas | 2005 |
Formation of 8-nitroguanine in blood of patients with inflammatory gouty arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Gouty; C-Reactive Protein; Chromatography, Hi | 2005 |
Vitamin A deficiency induces prooxidant environment and inflammation in rat aorta.
Topics: Animals; Antioxidants; Aorta; Body Weight; Inflammation; Lipid Peroxidation; Male; NF-kappa B; Nitra | 2005 |
Differential contribution of hepatitis C virus NS5A and core proteins to the induction of oxidative and nitrosative stress in human hepatocyte-derived cells.
Topics: Cell Line; Flow Cytometry; Genes, Reporter; Hepacivirus; Hepatocytes; Humans; Inflammation; Lucifera | 2005 |
Inhibition of TNF-alpha improves indomethacin-induced enteropathy in rats by modulating iNOS expression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Down-Regulation; Ileitis; | 2005 |
Anti-inflammatory evaluation of gardenia extract, geniposide and genipin.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fru | 2006 |
Suppression of angioplasty-related inflammation by pre-procedural treatment with trimetazidine.
Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; C-Reactive Protein; Coronary Disease; Female; Huma | 2006 |
Respiratory syncytial virus infection in a murine model of cystic fibrosis.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Inflammation; Lung; Lymph | 2006 |
Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxan
Topics: Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein | 2006 |
One-electron oxidation of DNA and inflammation processes.
Topics: Carbonates; DNA; DNA Damage; Electrons; Guanine; Inflammation; Nitrates; Oxidation-Reduction | 2006 |
Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome.
Topics: Animals; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Chromatography, | 2006 |
Exhaled breath condensate nitrite/nitrate and pH in relation to pediatric asthma control and exhaled nitric oxide.
Topics: Asthma; Breath Tests; Child; Cross-Sectional Studies; Exhalation; Female; Humans; Hydrogen-Ion Conce | 2006 |
The effect of substance P on nitric oxide release in a rheumatoid arthritis model.
Topics: Aged; Animals; Arthritis, Rheumatoid; Cells, Cultured; Disease Models, Animal; Female; Gene Expressi | 2006 |
Pro-inflammatory effects of early non-enzymatic glycated proteins in human mesothelial cells vary with cell donor's age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cells, Cultured; Cyclooxygenase 2; Cytokines; Epithelium; Gen | 2006 |
[A study on the relevance of airway inflammatory indices in induced sputum and airway hyperresponsiveness in asthmatics].
Topics: Adolescent; Adult; Asthma; Case-Control Studies; Eosinophils; Female; Humans; Inflammation; Male; Mi | 2006 |
Inhaled nitric oxide attenuates reperfusion inflammatory responses in humans.
Topics: Administration, Inhalation; Adult; Female; Humans; Inflammation; Lipid Peroxides; Lower Extremity; M | 2007 |
Effect of aspirin, paracetamol and their nitric oxide donating derivatives on exudate cytokine and PGE2 production in zymosan-induced air pouch inflammation in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2007 |
Measurement of IL-13-induced iNOS-derived gas phase nitric oxide in human bronchial epithelial cells.
Topics: Air; Asthma; Bronchi; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Humans; H | 2007 |
Caveolae nitration of Janus kinase-2 at the 1007Y-1008Y site: coordinating inflammatory response and metabolic hormone readjustment within the somatotropic axis.
Topics: Amino Acid Sequence; Animals; Antibodies; Antioxidants; Aspartic Acid; Binding Sites; Cattle; Caveol | 2007 |
Serum amino acid profile in patients with acute pancreatitis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amino Acids; Arginase; Female; Humans; Inflammation; | 2008 |
Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.
Topics: Adipose Tissue; Adiposity; Animals; Blood Pressure; Catecholamines; Dietary Fats; Drug Administratio | 2007 |
Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.
Topics: Animals; Benzoquinones; Chemokines; Cytokines; HSP90 Heat-Shock Proteins; Inflammation; Inflammation | 2007 |
Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo.
Topics: Animals; Apoptosis; Azoxymethane; Cell Count; Cell Line, Tumor; Cell Proliferation; Chemoprevention; | 2007 |
Effects of PM2.5 collected from Cache Valley Utah on genes associated with the inflammatory response in human lung cells.
Topics: Caspase 3; Cells, Cultured; Cytotoxicity Tests, Immunologic; Humans; Inflammation; Interleukins; Lun | 2007 |
Pro-inflammatory cytokines and oxidative stress/antioxidant parameters characterize the bio-humoral profile of early cachexia in lung cancer patients.
Topics: Aged; Anorexia; Antioxidants; Cachexia; Cytokines; Female; Glutathione; Humans; Inflammation; Interl | 2007 |
Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteries; Atherosclerosis; Cell Adhesion; Chlo | 2008 |
Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.
Topics: Animals; Colitis; Cyclic GMP; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Guanylate | 2008 |
Source apportionment of particulate matter in the U.S. and associations with lung inflammatory markers.
Topics: Air Pollutants; Biomarkers; Cells, Cultured; Cities; Cyclooxygenase 2; Epithelial Cells; Heme Oxygen | 2008 |
Effects of dietary nitrite and nitrate on experimentally-induced inflammation in the rat.
Topics: Animals; Body Weight; Collagen; Diet; Glycosaminoglycans; Granuloma; Inflammation; Nitrates; Nitrite | 1983 |
Mammalian nitrate biochemistry: metabolism and endogenous synthesis.
Topics: Acetates; Animals; Carrageenan; Humans; Inflammation; Lipopolysaccharides; Nitrates; Rats; Turpentin | 1984 |
Evidence for in vivo peroxynitrite production in human acute lung injury.
Topics: Cadaver; Child; Humans; Immunohistochemistry; Inflammation; Lung; Lung Diseases; Nitrates | 1995 |
The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence.
Topics: Administration, Inhalation; Animals; Arginine; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease | 1994 |
A diclofenac derivative without ulcerogenic properties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Diclofenac; Gastric Mucosa; Inflam | 1994 |
Nitration of tyrosine by hydrogen peroxide and nitrite.
Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxylation; Inflammation; Iron; Nitrates; Oxidativ | 1995 |
Amelioration of chronic inflammation by ingestion of elemental diet in a rat model of granulomatous enteritis.
Topics: Amino Acids; Animals; Crohn Disease; Food, Formulated; Immunohistochemistry; Inflammation; Intestina | 1997 |
Relation between pro- and anti-inflammatory cytokines and the production of nitric oxide (NO) in severe sepsis.
Topics: Antigens, CD; Female; Humans; Inflammation; Interleukin-10; Interleukin-6; Interleukin-8; Interleuki | 1997 |
Inflammation and NO(X)-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection.
Topics: Animals; Blood Proteins; Cell Line; Chromatography, High Pressure Liquid; Electrochemistry; Gas Chro | 1997 |
Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats.
Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Inflammation; Lung; Male; Myocardial Ischemia; Myoca | 1997 |
The possible role of peroxynitrite in Alzheimer's disease: a simple hypothesis that could be tested more thoroughly.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Anti-Inflammatory Agents; Antioxidants; Humans; I | 1997 |
Peroxynitrite. An apoptotic agent in HL-60 cells.
Topics: Apoptosis; Cell Division; DNA Fragmentation; Glutathione; HL-60 Cells; Humans; Inflammation; Nitrate | 1997 |
Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats.
Topics: Amino Acid Sequence; Animals; Antibodies; Bile; Bile Canaliculi; Bile Ducts; Endotoxemia; Endotoxins | 1997 |
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Topics: Animals; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; | 1997 |
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation.
Topics: Animals; Carrageenan; Disease Models, Animal; Edema; Enzyme Inhibitors; Free Radical Scavengers; Gua | 1998 |
Peroxynitrite-induced apoptosis in epithelial (T84) and macrophage (RAW 264.7) cell lines: effect of legume-derived polyphenols (phytolens).
Topics: Animals; Antioxidants; Apoptosis; Bepridil; Biphenyl Compounds; Cell Division; Cell Line; Cell Survi | 1997 |
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation.
Topics: Animals; Anti-Inflammatory Agents; Benzamides; Carrageenan; Enzyme Inhibitors; Exudates and Transuda | 1998 |
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart; | 1998 |
Characterization of the cytoprotective action of peroxynitrite decomposition catalysts.
Topics: Animals; Catalysis; Cell Death; Ferric Compounds; Humans; Inflammation; Metalloporphyrins; Nitrates; | 1998 |
Peroxynitrite formation within the central nervous system in active multiple sclerosis.
Topics: Central Nervous System; Humans; Immunohistochemistry; Inflammation; Multiple Sclerosis; Nervous Syst | 1998 |
Nitric oxide and peroxynitrite in lipid peroxidation.
Topics: Animals; Antioxidants; Humans; Inflammation; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; | 1998 |
Antiinflammatory actions of cat's claw: the role of NF-kappaB.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Cells, Cultured; Electrophoresis; Enzym | 1998 |
Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response.
Topics: Antioxidants; Blood Proteins; Calcium; Cells, Cultured; Humans; Inflammation; N-Formylmethionine Leu | 1999 |
The cytochrome P450 suicide inhibitor, 1-aminobenzotriazole, sensitizes rats to zymosan-induced toxicity.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Inflamm | 1998 |
Oral spermine administration inhibits nitric oxide-mediated intestinal damage and levels of systemic inflammatory mediators in a mouse endotoxin model.
Topics: Administration, Oral; Animals; Disease Models, Animal; Escherichia coli; Female; Immunohistochemistr | 1999 |
Role of inducible nitric oxide synthase in leukocyte extravasation in vivo.
Topics: Acute Disease; Animals; Ascitic Fluid; Blotting, Western; Cell Movement; Disease Models, Animal; Enz | 1999 |
Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia.
Topics: Animals; Azides; Cell Survival; Cells, Cultured; Enzyme Activation; Glutamate Dehydrogenase; Inflamm | 1999 |
Enhanced benzene-induced DNA damage in PMA-stimulated cells in vitro and in LPS-treated animals.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Benzene; Bone Marrow Cells; Cells, Cultured; Deoxyguanosine; D | 1999 |
Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse.
Topics: Animals; Anti-Ulcer Agents; Blood Proteins; Carrageenan; Chromatography, High Pressure Liquid; Cimet | 1999 |
Nitric oxide metabolites in induced sputum: a marker of airway inflammation in asthmatic subjects.
Topics: Adolescent; Adult; Aged; Asthma; Biomarkers; Eosinophils; Female; Humans; Inflammation; Interleukin- | 1999 |
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Topics: Animals; Benzamides; Complement Activation; Dose-Response Relationship, Drug; Edema; Enzyme Inhibito | 1999 |
Role of peroxynitrite as a mediator of pathophysiological alterations in experimental pneumococcal meningitis.
Topics: Animals; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Free Radical Scavengers; Inflammation; Int | 1999 |
Mercaptoethylguanidine inhibits the inflammatory response in a murine model of chronic infection with Pseudomonas aeruginosa.
Topics: Anesthesia; Animals; Biomarkers; Body Weight; Cytokines; Enzyme Inhibitors; Female; Guanidines; Infl | 2000 |
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Topics: Animals; Antioxidants; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema | 2000 |
Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Collagen; Cyclooxygenase 1 | 2000 |
Different roles for nitrogen monoxide and peroxynitrite in lipid peroxidation induced by activated neutrophils.
Topics: Animals; Arginine; Carrageenan; Deferoxamine; Exudates and Transudates; Granuloma; Inflammation; Lip | 2000 |
Regulation of inflammatory responses to Bordetella pertussis by N(G)-monomethyl-L-arginine in mice intranasally infected.
Topics: Animals; Bordetella pertussis; Bronchoalveolar Lavage Fluid; Female; Inflammation; Interferon-gamma; | 1999 |
Inhibition of inflammatory species by titanium surfaces.
Topics: Biocompatible Materials; Implants, Experimental; Inflammation; Inflammation Mediators; Nitrates; Rea | 2000 |
Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation.
Topics: Animals; Cells, Cultured; Dopamine; Immunohistochemistry; Inflammation; Interleukin-1; Lipopolysacch | 2000 |
Elevation of nitrotyrosine and nitrate concentrations in cystic fibrosis sputum.
Topics: Adolescent; Adult; Cystic Fibrosis; Female; Free Radicals; Humans; Inflammation; Male; Nitrates; Nit | 2000 |
Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Electron Spin Resonance Spectroscop | 2000 |
P-selectin participates in cardiopulmonary bypass-induced inflammatory response in association with nitric oxide and peroxynitrite production.
Topics: Animals; Antibodies, Monoclonal; Cardiopulmonary Bypass; Inflammation; Interleukin-6; Male; Nitrates | 2000 |
Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxynitrite.
Topics: Blotting, Western; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electron Spin Resonance S | 2000 |
Lipopolysaccharide binding protein potentiates airway reactivity in a murine model of allergic asthma.
Topics: Acute-Phase Proteins; Adjuvants, Immunologic; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperr | 2001 |
Acidic fibroblast growth factor attenuates the cytotoxic effects of peroxynitrite in primary human osteoblast precursors.
Topics: Apoptosis; Cell Differentiation; Cell Division; Cells, Cultured; Cytotoxicity, Immunologic; Drug Eva | 2001 |
Association of reactive nitrogen species metabolites, myeloperoxidase, and airway inflammation in lung transplants.
Topics: Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Enzyme-Linked Immunosorbent Assay; Female; Hu | 2001 |
Inflammatory macrophage nuclear factor-kappaB and proteasome activity are inhibited following exposure to inhaled isobutyl nitrite.
Topics: Administration, Inhalation; Animals; Butanes; Cysteine Endopeptidases; Cytotoxicity, Immunologic; De | 2001 |
Cyclooxygenase-2 protein and prostaglandin E(2) production are up-regulated in a rat bladder inflammation model.
Topics: Administration, Intravesical; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo | 2001 |
Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Chimera; Endotoxemia; In Vitro Techniques; | 2001 |
Aminoethyl-isothiourea inhibits leukocyte production of reactive oxygen species and proinflammatory cytokines induced by streptococcal cell wall components in human whole blood.
Topics: Cell Survival; Cell Wall; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; In | 2001 |
Peripheral nitric oxide in carrageenan-induced inflammation.
Topics: Animals; Carrageenan; Drug Interactions; Edema; Enzyme Inhibitors; Guanidines; Hyperalgesia; Inflamm | 2001 |
Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Cytokines; Disease Models, Anima | 2002 |
Serum levels of Hsp 72 measured early after trauma correlate with survival.
Topics: Analysis of Variance; Craniocerebral Trauma; Female; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; | 2002 |
Nitrogen oxide levels in patients after trauma and during sepsis.
Topics: Adult; Aged; Endotoxins; Female; Humans; Infections; Inflammation; Male; Middle Aged; Nitrates; Nitr | 1991 |