nitrates has been researched along with Hypotension in 77 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy." | 7.67 | Nifedipine-induced hypotension and mesenteric ischemia. ( Deppe, SA; Elliott, BM; Goglin, WK, 1989) |
| "Hypotension is one of the major complications in patients undergoing haemodialysis (HD), that is well evident in patients defined as "hypotension-prone." | 5.32 | Relationship of asymmetric dimethylarginine to haemodialysis hypotension. ( Albertazzi, A; Bellei, E; Bergamini, S; Iannone, A; Manfredini, P; Rota, C; Tomasi, A; Vandelli, L, 2004) |
| "A randomized single blind cross-over trial with placebo lead-in has been conducted in 71 anginal patients with arterial hypotension (group 1) and 38 ischemic heart disease patients with normal arterial pressure (group 2) to compare efficacy of therapy with isosorbide dinitrate (ID), sustac-forte (SF), isosorbide dinitrate retard (IDR) and trinitrolong (TN)." | 5.10 | [Nitrates in therapy of effort angina in hypotensive patients]. ( Borovkova, NV; Chernov, VI; Demochko, AV; Idrisova, EM; Karpov, RS; Kladieva, EA; Shishkina, AA; Vorob'eva, EV, 2003) |
| "Nitrates and nitrate-containing compounds are vasodilators used for the treatment of angina and heart failure." | 4.98 | A New Perspective on the Nitrate-Phosphodiesterase Type 5 Inhibitor Interaction. ( Goggin, P; Goldstein, I; Hackett, G; Kirby, MG; Kloner, RA; Osterloh, I; Parker, JD; Sadovsky, R, 2018) |
| "In previous studies we demonstrated that the administration of furosemide associated with L-arginine contributes to enhanced hypotension and induces greater water than electrolyte excretion, in both normal and expansion conditions." | 3.72 | Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion. ( Arranz, C; Balaszczuk, AM; Costa, MA; Elesgaray, R; Loria, A, 2004) |
| "We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy." | 3.67 | Nifedipine-induced hypotension and mesenteric ischemia. ( Deppe, SA; Elliott, BM; Goglin, WK, 1989) |
| "The effect of BRJ in ADPKD has not been previously tested." | 3.30 | Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial. ( Chau, K; Elhindi, J; Harris, DC; Lee, V; Munt, A; Nguyen, B; Rangan, GK; Sagar, PS; Saravanabavan, S; Sud, K; Vahedi, FA; Wong, N, 2023) |
| " After a 10- to 21-day washout period, subjects crossed over to either placebo or tadalafil, and nitrate dosing was repeated." | 2.71 | Time course of the interaction between tadalafil and nitrates. ( Denne, J; Emmick, JT; Hutter, AM; Jackson, G; Kloner, RA; Mitchell, MI, 2003) |
| "Patients with metastatic renal cell carcinoma receiving a 5-day continuous infusion of IL-2 (18 million IU/m2/d) who developed hypotension were treated with increasing doses of NMA, ranging from 3 to 36 mg/kg." | 2.69 | Strategies to reduce side effects of interleukin-2: evaluation of the antihypotensive agent NG-monomethyl-L-arginine. ( Fonseca, GA; Griffith, OW; Kilbourn, RG; Trissel, LA, 2000) |
| "Erectile dysfunction is a common problem affecting men." | 2.40 | Use of oral sildenafil (Viagra) in the treatment of erectile dysfunction. ( Licht, MR, 1999) |
| " We examined here whether ARG1 and ARG2 genotypes and haplotypes affect the changes in blood pressure and NO bioavailability in response to propofol." | 1.62 | Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability. ( Coeli-Lacchini, FB; Ferezin, LP; Ferreira, GC; Garcia, LV; Lacchini, R; Oliveira-Paula, GH; Paula-Garcia, WN; Pinheiro, LC; Tanus-Santos, JE, 2021) |
| "Metabolic acidosis has profound effects on vascular tone." | 1.43 | Acute but not chronic metabolic acidosis potentiates the acetylcholine-induced reduction in blood pressure: an endothelium-dependent effect. ( Albuquerque, AA; Capellini, VK; Celotto, AC; Evora, PR; Ferreira, LG; Rodrigues, AJ, 2016) |
| " In this clinical study, we investigated whether PD-mediated impairment of nitric oxide (NO) bioavailability and signaling, in patients with persistently low systolic blood pressure (SBP), can explain the occurrence of cerebral ischemia." | 1.43 | Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia. ( Bárány, P; Békássy, Z; Cananau, C; Carlström, M; Checa, A; Hansson, S; Krmar, RT; Lundberg, JO; Sartz, L; Svensson, A; Weitzberg, E; Westphal, S; Wheelock, CE; Wide, K, 2016) |
| ") significantly restored the hypotensive effect of bolus injection of GTN in rats made tolerants to organic nitrates via chronic administration of isosorbide-5-mononitrate (IS-5-MN), thus confirming the role of peroxynitrite overproduction in the development of tolerance to vascular responses induced by organic nitrates." | 1.40 | The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance. ( Carresi, C; Dagostino, C; Giancotti, LA; Gliozzi, M; Gratteri, S; Malara, N; Mollace, V; Muscoli, C; Muscoli, S; Musolino, V; Palma, E; Romeo, F; Sacco, I; Salvemini, D; Visalli, V; Vitale, C, 2014) |
| "Hypotension was not associated with increased postprocedural strokes (0." | 1.35 | Predictors of clinically significant postprocedural hypotension after carotid endarterectomy and carotid angioplasty with stenting. ( Dahn, MS; Divinagracia, T; Madej, O; McPhelimy, C; Menzoian, JO; Park, BD; Piccirillo, B; Ruby, S, 2009) |
| "Treatment with ibuprofen, either before or after ETX, partly restored the elevated levels of nitrite/nitrate." | 1.33 | Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock. ( Akbulut, H; Ayar, A; Canbaz, M; Celik, I; Vural, P, 2005) |
| "Patients with septic shock have a shortage in the availability of arginine associated with a slower production." | 1.33 | In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis. ( Balasubramanyam, A; Bandi, VP; Gopal, J; Guntupalli, K; Jahoor, F; Villalpando, S, 2006) |
| "In the modern era of pharmacologic treatment of erectile dysfunction, men with heart disease increasingly approach their physicians regarding the possibility of restoring sexual activity." | 1.33 | Sex, the heart, and heart failure. ( Brunner, H; Kiowski, W; Schalcher, C, 2006) |
| "Prazosin treatment prolonged the duration of NTG-induced MAP response by about 4-fold for all NTG doses examined (P < 0." | 1.32 | Prazosin potentiates the acute hypotensive effects of nitroglycerin but does not attenuate nitrate tolerance in normal conscious rats. ( Fung, HL; Wang, EQ, 2004) |
| "Hypotension is one of the major complications in patients undergoing haemodialysis (HD), that is well evident in patients defined as "hypotension-prone." | 1.32 | Relationship of asymmetric dimethylarginine to haemodialysis hypotension. ( Albertazzi, A; Bellei, E; Bergamini, S; Iannone, A; Manfredini, P; Rota, C; Tomasi, A; Vandelli, L, 2004) |
| "To elucidate the role of NO in RDS and low blood pressure, we determined the endogenous NO production in infants with and without RDS by measuring urinary nitrite and nitrate excretions and plasma cGMP levels." | 1.31 | Nitric oxide production and plasma cyclic guanosine monophosphate in premature infants with respiratory distress syndrome. ( Egberts, J; Hempenius, I; Krediet, TG; Valk, L; van Bel, F, 2002) |
| "Hypotension is a major cardiovascular complication of hemodialysis, and enhanced production of nitric oxide (NO) may be involved in hemodialysis hypotension." | 1.31 | Association of human hepatocyte growth factor with hemodialysis hypotension. ( Mabuchi, H; Maruyama, Y; Nishimura, M; Takahashi, H; Ushiyama, M; Yoshimura, M, 2000) |
| "The hypotension was also inhibited when APC was administered 30 minutes after ET administration." | 1.31 | Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide. ( Harada, N; Isobe, H; Mizutani, A; Nagasaki, A; Okabe, K; Okajima, K; Uchiba, M, 2001) |
| "Children with the sepsis syndrome, particularly those patients with hypotension, have increased total serum nitrite and nitrate concentrations that likely reflect increased endogenous production of nitric oxide." | 1.29 | Increased serum nitrite and nitrate concentrations in children with the sepsis syndrome. ( Burckart, G; Carcillo, JA; Janosky, JE; Shah, N; Wong, HR, 1995) |
| "Recurrent dialysis hypotension is common in long-term dialysis patients." | 1.29 | Failure of arginine-vasopressin and other pressor hormones to increase in severe recurrent dialysis hypotension. ( Friess, U; Gross, P; Rascher, W; Ritz, E, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (7.79) | 18.7374 |
| 1990's | 19 (24.68) | 18.2507 |
| 2000's | 38 (49.35) | 29.6817 |
| 2010's | 10 (12.99) | 24.3611 |
| 2020's | 4 (5.19) | 2.80 |
| Authors | Studies |
|---|---|
| Sagar, PS | 1 |
| Munt, A | 1 |
| Saravanabavan, S | 1 |
| Vahedi, FA | 1 |
| Elhindi, J | 1 |
| Nguyen, B | 1 |
| Chau, K | 1 |
| Harris, DC | 1 |
| Lee, V | 1 |
| Sud, K | 1 |
| Wong, N | 1 |
| Rangan, GK | 1 |
| Knuuti, J | 1 |
| Wijns, W | 1 |
| Funck-Brentano, C | 1 |
| Kallistratos, MS | 1 |
| Poulimenos, LE | 1 |
| Manolis, AJ | 1 |
| Oliveira-Paula, GH | 1 |
| Coeli-Lacchini, FB | 1 |
| Ferezin, LP | 1 |
| Ferreira, GC | 1 |
| Pinheiro, LC | 1 |
| Paula-Garcia, WN | 1 |
| Garcia, LV | 1 |
| Tanus-Santos, JE | 1 |
| Lacchini, R | 1 |
| Kloner, RA | 2 |
| Goggin, P | 1 |
| Goldstein, I | 1 |
| Hackett, G | 1 |
| Kirby, MG | 1 |
| Osterloh, I | 1 |
| Parker, JD | 1 |
| Sadovsky, R | 1 |
| Michalski, T | 1 |
| Franz, A | 1 |
| Queiroz, TM | 2 |
| Mendes-Júnior, LG | 1 |
| Guimarães, DD | 1 |
| França-Silva, MS | 1 |
| Nalivaiko, E | 1 |
| Braga, VA | 1 |
| Chang, CT | 1 |
| Chien, MH | 1 |
| Yang, KL | 1 |
| Yu, CC | 1 |
| Hsu, JF | 1 |
| Wang, IK | 1 |
| Lim, PS | 1 |
| Huang, CC | 1 |
| Machado, NT | 1 |
| Maciel, PM | 1 |
| Alustau, MC | 1 |
| Furtado, FF | 1 |
| Assis, VL | 1 |
| Veras, RC | 1 |
| Araújo, IG | 1 |
| Athayde-Filho, PF | 1 |
| Medeiros, IA | 1 |
| Mollace, V | 1 |
| Muscoli, C | 1 |
| Dagostino, C | 1 |
| Giancotti, LA | 1 |
| Gliozzi, M | 1 |
| Sacco, I | 1 |
| Visalli, V | 1 |
| Gratteri, S | 1 |
| Palma, E | 1 |
| Malara, N | 1 |
| Musolino, V | 1 |
| Carresi, C | 1 |
| Muscoli, S | 1 |
| Vitale, C | 1 |
| Salvemini, D | 1 |
| Romeo, F | 1 |
| Celotto, AC | 1 |
| Ferreira, LG | 1 |
| Capellini, VK | 1 |
| Albuquerque, AA | 1 |
| Rodrigues, AJ | 1 |
| Evora, PR | 2 |
| Carlström, M | 1 |
| Cananau, C | 1 |
| Checa, A | 1 |
| Wide, K | 1 |
| Sartz, L | 1 |
| Svensson, A | 1 |
| Wheelock, CE | 1 |
| Westphal, S | 1 |
| Békássy, Z | 1 |
| Bárány, P | 1 |
| Lundberg, JO | 1 |
| Hansson, S | 1 |
| Weitzberg, E | 1 |
| Krmar, RT | 1 |
| Park, BD | 1 |
| Divinagracia, T | 1 |
| Madej, O | 1 |
| McPhelimy, C | 1 |
| Piccirillo, B | 1 |
| Dahn, MS | 1 |
| Ruby, S | 1 |
| Menzoian, JO | 1 |
| Kapil, V | 1 |
| Milsom, AB | 1 |
| Okorie, M | 1 |
| Maleki-Toyserkani, S | 1 |
| Akram, F | 1 |
| Rehman, F | 1 |
| Arghandawi, S | 1 |
| Pearl, V | 1 |
| Benjamin, N | 1 |
| Loukogeorgakis, S | 1 |
| Macallister, R | 1 |
| Hobbs, AJ | 1 |
| Webb, AJ | 1 |
| Ahluwalia, A | 1 |
| Gómez, H | 1 |
| Mesquida, J | 1 |
| Hermus, L | 1 |
| Polanco, P | 1 |
| Kim, HK | 1 |
| Zenker, S | 1 |
| Torres, A | 1 |
| Namas, R | 1 |
| Vodovotz, Y | 1 |
| Clermont, G | 1 |
| Puyana, JC | 1 |
| Pinsky, MR | 1 |
| Krediet, TG | 1 |
| Valk, L | 1 |
| Hempenius, I | 1 |
| Egberts, J | 1 |
| van Bel, F | 1 |
| RICCI, GC | 1 |
| RICORDATI, M | 1 |
| Hutter, AM | 1 |
| Emmick, JT | 1 |
| Mitchell, MI | 1 |
| Denne, J | 1 |
| Jackson, G | 1 |
| Idrisova, EM | 1 |
| Borovkova, NV | 1 |
| Kladieva, EA | 1 |
| Chernov, VI | 1 |
| Demochko, AV | 1 |
| Shishkina, AA | 1 |
| Vorob'eva, EV | 1 |
| Karpov, RS | 1 |
| Silvani, S | 1 |
| Padoan, G | 1 |
| Guidi, AR | 1 |
| Bianchedi, G | 1 |
| Maresta, A | 1 |
| Wang, EQ | 1 |
| Fung, HL | 1 |
| Costa, MA | 1 |
| Loria, A | 1 |
| Elesgaray, R | 1 |
| Balaszczuk, AM | 1 |
| Arranz, C | 1 |
| Molor-Erdene, P | 1 |
| Okajima, K | 5 |
| Isobe, H | 5 |
| Uchiba, M | 5 |
| Harada, N | 4 |
| Okabe, H | 3 |
| Bergamini, S | 1 |
| Vandelli, L | 1 |
| Bellei, E | 1 |
| Rota, C | 1 |
| Manfredini, P | 1 |
| Tomasi, A | 1 |
| Albertazzi, A | 1 |
| Iannone, A | 1 |
| Buzato, MA | 1 |
| Viaro, F | 1 |
| Piccinato, CE | 1 |
| Akbulut, H | 1 |
| Celik, I | 1 |
| Ayar, A | 1 |
| Vural, P | 1 |
| Canbaz, M | 1 |
| Aguiar-Souto, P | 1 |
| Silva-Melchor, L | 1 |
| Ortigosa-Aso, FJ | 1 |
| Villalpando, S | 1 |
| Gopal, J | 1 |
| Balasubramanyam, A | 1 |
| Bandi, VP | 1 |
| Guntupalli, K | 1 |
| Jahoor, F | 1 |
| Kiowski, W | 1 |
| Brunner, H | 1 |
| Schalcher, C | 1 |
| El-Mas, MM | 1 |
| Fan, M | 1 |
| Abdel-Rahman, AA | 1 |
| Lauer, S | 1 |
| Daudel, F | 1 |
| Traber, DL | 1 |
| Nofer, JR | 1 |
| Ertmer, C | 1 |
| Morelli, A | 1 |
| Van Aken, H | 1 |
| Lange, M | 1 |
| Rehberg, S | 1 |
| Ellger, B | 1 |
| Stubbe, HD | 1 |
| Kruse, C | 1 |
| Bone, HG | 1 |
| Westphal, M | 1 |
| Preiser, JC | 1 |
| Zhang, H | 1 |
| Wachel, D | 1 |
| Boeynaems, JM | 1 |
| Buurman, W | 1 |
| Vincent, JL | 1 |
| Wong, HR | 1 |
| Carcillo, JA | 1 |
| Burckart, G | 1 |
| Shah, N | 1 |
| Janosky, JE | 1 |
| Yokokawa, K | 1 |
| Mankus, R | 1 |
| Saklayen, MG | 1 |
| Kohno, M | 1 |
| Yasunari, K | 1 |
| Minami, M | 1 |
| Kano, H | 1 |
| Horio, T | 1 |
| Takeda, T | 1 |
| Mandel, AK | 1 |
| Benedini, F | 1 |
| Bertolini, G | 1 |
| Cereda, R | 1 |
| Donà, G | 1 |
| Gromo, G | 1 |
| Levi, S | 1 |
| Mizrahi, J | 1 |
| Sala, A | 1 |
| Evans, T | 1 |
| Carpenter, A | 1 |
| Kinderman, H | 1 |
| Cohen, J | 1 |
| Friess, U | 1 |
| Rascher, W | 1 |
| Ritz, E | 1 |
| Gross, P | 1 |
| Kang, ES | 2 |
| Acchiardo, SR | 2 |
| Wang, YB | 1 |
| Tevlin, MT | 2 |
| Hughes, T | 1 |
| Cardoso, S | 1 |
| Hattori, Y | 1 |
| Akimoto, K | 1 |
| Nakanishi, N | 1 |
| Kasai, K | 1 |
| Wu, CC | 2 |
| Yen, MH | 2 |
| Liao, MH | 1 |
| Nishimura, M | 3 |
| Takahashi, H | 3 |
| Maruyama, K | 1 |
| Ohtsuka, K | 1 |
| Nanbu, A | 1 |
| Hara, K | 1 |
| Yoshimura, M | 3 |
| Leach, M | 1 |
| Hamilton, LC | 1 |
| Olbrich, A | 1 |
| Wray, GM | 2 |
| Thiemermann, C | 2 |
| Hinds, CJ | 1 |
| Hashimoto, M | 1 |
| Shinozuka, K | 1 |
| Tanabe, Y | 1 |
| Gamoh, S | 1 |
| Hara, T | 1 |
| Hossain, MS | 1 |
| Kwon, YM | 1 |
| Kunitomo, M | 1 |
| Masumura, S | 1 |
| Licht, MR | 1 |
| Halpern, NA | 1 |
| Akinola, AB | 1 |
| Land, JM | 1 |
| Mathias, CJ | 1 |
| Giovannoni, G | 1 |
| Magnifico, F | 1 |
| Puvi-Rajasingham, S | 1 |
| Smith, GD | 1 |
| Watson, L | 1 |
| Cases, A | 1 |
| Esforzado, N | 1 |
| Lario, S | 1 |
| Vera, M | 1 |
| Lopez-Pedret, J | 1 |
| Rivera-Fillat, F | 1 |
| Jimenez, W | 1 |
| Kilbourn, RG | 1 |
| Fonseca, GA | 1 |
| Trissel, LA | 1 |
| Griffith, OW | 1 |
| Yamashita, T | 1 |
| Kawashima, S | 1 |
| Ohashi, Y | 1 |
| Ozaki, M | 1 |
| Ueyama, T | 1 |
| Ishida, T | 1 |
| Inoue, N | 1 |
| Hirata, K | 1 |
| Akita, H | 1 |
| Yokoyama, M | 1 |
| Jamil, KM | 1 |
| Yokoyama, K | 1 |
| Takemoto, F | 1 |
| Hara, S | 1 |
| Yamada, A | 1 |
| Biron, CR | 1 |
| Khoury, V | 1 |
| Kritharides, L | 1 |
| Ushiyama, M | 1 |
| Maruyama, Y | 1 |
| Mabuchi, H | 1 |
| Bian, Z | 1 |
| Yan, ZQ | 1 |
| Hansson, GK | 1 |
| Thorén, P | 1 |
| Normark, S | 1 |
| Miles, DE | 1 |
| Cates, TB | 1 |
| Matsuo, I | 1 |
| Hirooka, Y | 1 |
| Hironaga, K | 1 |
| Eshima, K | 1 |
| Shigematsu, H | 1 |
| Shihara, M | 1 |
| Sakai, K | 1 |
| Takeshita, A | 1 |
| DeWitt, DS | 1 |
| Mathew, BP | 1 |
| Chaisson, JM | 1 |
| Prough, DS | 1 |
| Mailman, D | 1 |
| Guntuku, S | 1 |
| Bhuiyan, MB | 1 |
| Murad, F | 1 |
| Mizutani, T | 1 |
| Takahashi, S | 1 |
| Kihara, S | 1 |
| Toyooka, H | 1 |
| Peer, G | 1 |
| Itzhakov, E | 1 |
| Wollman, Y | 1 |
| Chernihovsky, T | 1 |
| Grosskopf, I | 1 |
| Segev, D | 1 |
| Silverberg, D | 1 |
| Blum, M | 1 |
| Schwartz, D | 1 |
| Iaina, A | 1 |
| Schwemmer, M | 1 |
| Bassenge, E | 1 |
| Stoeter, M | 1 |
| Hartmann, B | 1 |
| Hess, U | 1 |
| Fink, B | 1 |
| Howes, L | 1 |
| Mizutani, A | 1 |
| Nagasaki, A | 1 |
| Okabe, K | 1 |
| Enkhbaatar, P | 1 |
| Metcalf, K | 1 |
| Jungersten, L | 1 |
| Lisander, B | 1 |
| Goglin, WK | 1 |
| Elliott, BM | 1 |
| Deppe, SA | 1 |
| Judge, TG | 1 |
| Olesch, K | 1 |
| Belz, GG | 1 |
| Heesemann, E | 1 |
| Andersen, ME | 1 |
| Mehl, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris: Randomised, Double Blind, Placebo Controlled Trial[NCT04270071] | Phase 4 | 80 participants (Anticipated) | Interventional | 2020-12-31 | Not yet recruiting | ||
| [NCT02442232] | 65 participants (Actual) | Observational | 2015-08-31 | Completed | |||
| Investigation of the Sex Differences in Oral Microbiota and Their Effect on Circulating Nitrite Levels[NCT01583803] | 24 participants (Anticipated) | Observational | 2012-06-30 | Active, not recruiting | |||
| The Acute Effect of Beetroot Juice on Circulating Nitrate and Nitrite Levels and Blood Pressure in Normotensives and Hypertensives[NCT01236872] | 15 participants (Actual) | Interventional | 2009-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nitrates and Hypotension
| Article | Year |
|---|---|
A New Perspective on the Nitrate-Phosphodiesterase Type 5 Inhibitor Interaction.
Topics: Angina Pectoris; Animals; Blood Pressure; Contraindications, Drug; Drug Interactions; Erectile Dysfu | 2018 |
Use of oral sildenafil (Viagra) in the treatment of erectile dysfunction.
Topics: Clinical Trials as Topic; Contraindications; Drug Synergism; Erectile Dysfunction; Humans; Hypotensi | 1999 |
Today's strategies for treating postoperative hypertension. Immediate evaluation and targeted treatment are required.
Topics: Adrenergic beta-Antagonists; Algorithms; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 1995 |
Vasodilators..
Topics: Adrenergic alpha-Antagonists; Aminophylline; Angina Pectoris; Bradycardia; Bronchial Diseases; Cereb | 1974 |
7 trials available for nitrates and Hypotension
| Article | Year |
|---|---|
Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial.
Topics: Adult; Antioxidants; Beta vulgaris; Blood Pressure; Dietary Supplements; Double-Blind Method; Humans | 2023 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Time course of the interaction between tadalafil and nitrates.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Carbolines; Contraindications; Cross-Over Studies; | 2003 |
[Nitrates in therapy of effort angina in hypotensive patients].
Topics: Angina Pectoris; Cross-Over Studies; Exercise Test; Humans; Hypotension; Isosorbide Dinitrate; Male; | 2003 |
Increased nitric oxide production in patients with hypotension during hemodialysis.
Topics: Aged; Cyclic GMP; Endothelins; Female; Heparin; Humans; Hypotension; Male; Middle Aged; Nitrates; Ni | 1995 |
Strategies to reduce side effects of interleukin-2: evaluation of the antihypotensive agent NG-monomethyl-L-arginine.
Topics: Adult; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hypote | 2000 |
Methylene blue, a nitric oxide inhibitor, prevents haemodialysis hypotension.
Topics: Adult; Aged; Blood Platelets; Blood Pressure; Diastole; Enzyme Inhibitors; Humans; Hypotension; Kidn | 2001 |
66 other studies available for nitrates and Hypotension
| Article | Year |
|---|---|
Anti-ischaemic medication must be adapted to each patient's characteristics and preferences in patients with chronic coronary syndromes.
Topics: Angina, Stable; Calcium Channel Blockers; Humans; Hypotension; Nitrates; Syndrome | 2020 |
Beta blockers, calcium channel blockers, and long-acting nitrates for patients with stable angina and low blood pressure levels: should this recommendation be reconsidered?
Topics: Adrenergic beta-Antagonists; Angina, Stable; Calcium Channel Blockers; Humans; Hypotension; Nitrates | 2020 |
Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability.
Topics: Adult; Aged; Anesthetics, Intravenous; Arginase; Female; Genotype; Haplotypes; Humans; Hypotension; | 2021 |
[53-year-old patient with hypotension].
Topics: Administration, Oral; Cyanosis; Diagnosis, Differential; Humans; Hypotension; Male; Methemoglobinemi | 2013 |
Cardiorespiratory effects induced by 2-nitrate-1,3-dibuthoxypropan are reduced by nitric oxide scavenger in rats.
Topics: Animals; Arterial Pressure; Bradycardia; Cardiovascular Agents; Consciousness; Dose-Response Relatio | 2014 |
Nitric oxide production and blood pressure reduction during haemodialysis.
Topics: Aged; Blood Pressure; Case-Control Studies; Dialysis Solutions; Female; Humans; Hypotension; Male; M | 2014 |
Nitric oxide as a target for the hypotensive and vasorelaxing effects induced by (Z)-ethyl 12-nitrooxy-octadec-9-enoate in rats.
Topics: Animals; Aorta; Bradycardia; Cell Survival; Cells, Cultured; Hypotension; In Vitro Techniques; Male; | 2014 |
The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance.
Topics: Aldehyde Dehydrogenase; Animals; Aorta; Blood Platelets; Cyclic GMP; Drug Tolerance; Endothelium, Va | 2014 |
Acute but not chronic metabolic acidosis potentiates the acetylcholine-induced reduction in blood pressure: an endothelium-dependent effect.
Topics: Acetylcholine; Acid-Base Imbalance; Acidosis; Acute Disease; Animals; Bicarbonates; Blood Pressure; | 2016 |
Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia.
Topics: Arginine; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclic GMP; Female; Ho | 2016 |
Predictors of clinically significant postprocedural hypotension after carotid endarterectomy and carotid angioplasty with stenting.
Topics: Aged; Angioplasty; Carotid Stenosis; Connecticut; Endarterectomy, Carotid; Female; Humans; Hypotensi | 2009 |
Physiologic responses to severe hemorrhagic shock and the genesis of cardiovascular collapse: can irreversibility be anticipated?
Topics: Animals; Autonomic Nervous System; Blood Pressure; Catecholamines; Cytokines; Disease Models, Animal | 2012 |
Nitric oxide production and plasma cyclic guanosine monophosphate in premature infants with respiratory distress syndrome.
Topics: Blood Pressure; Cyclic GMP; Gestational Age; Humans; Hypotension; Infant, Newborn; Infant, Premature | 2002 |
[Clinical experiences with a new hypotensive drug].
Topics: Antihypertensive Agents; Hypotension; Nitrates; Urethane | 1957 |
Cerebral vasoconstriction in neurally mediated syncope: relationship with type of head-up tilt test response.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Bradycardia; Cerebrovascular Circulation; Diastole; Elec | 2003 |
Prazosin potentiates the acute hypotensive effects of nitroglycerin but does not attenuate nitrate tolerance in normal conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Drug Synergism; Drug Tolerance; Hypotension; | 2004 |
Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion.
Topics: Animals; Blood Pressure; Blood Volume; Carbon Radioisotopes; Citrulline; Diuresis; Diuretics; Extrac | 2004 |
Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression.
Topics: Animals; Drug Interactions; Glycoproteins; Humans; Hypotension; In Vitro Techniques; Insulin-Like Gr | 2005 |
Relationship of asymmetric dimethylarginine to haemodialysis hypotension.
Topics: Aged; Arginine; Female; Humans; Hypotension; Male; Nitrates; Nitrites; Renal Dialysis; Tumor Necrosi | 2004 |
The use of methylene blue in the treatment of anaphylactic shock induced by compound 48/80: experimental studies in rabbits.
Topics: Adrenal Cortex Hormones; Anaphylaxis; Animals; Arteries; Blood Pressure; Dose-Response Relationship, | 2005 |
Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypotension; Ibuprofen; | 2005 |
Chronic stable angina.
Topics: Acetanilides; Angina Pectoris; Chronic Disease; Drug Interactions; Enzyme Inhibitors; Humans; Hypote | 2005 |
Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats.
Topics: Animals; Antithrombins; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Calciton | 2006 |
In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis.
Topics: Adult; Aged; Arginine; Case-Control Studies; Critical Illness; Female; Glomerular Filtration Rate; H | 2006 |
Sex, the heart, and heart failure.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Cardiovascular Diseases; Contraindications; Erectile Dysfunctio | 2006 |
Endotoxemia-mediated induction of cardiac inducible nitric-oxide synthase expression accounts for the hypotensive effect of ethanol in female rats.
Topics: Amidines; Ampicillin; Animals; Anti-Bacterial Agents; Benzylamines; Blood Pressure; Cardiac Output; | 2008 |
Somatostatin infusion increases intestinal ischemia and does not improve vasoconstrictor response to norepinephrine in ovine endotoxemia.
Topics: Animals; Endotoxemia; Female; Hemodynamics; Hypotension; Ischemia; Nitrates; Nitrites; Norepinephrin | 2008 |
Is endotoxin-induced hypotension related to nitric oxide formation?
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Dogs; Endotoxins; Hemodynamics; Hypotension; Nitrates | 1994 |
Increased serum nitrite and nitrate concentrations in children with the sepsis syndrome.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Hypotension; Infant; Infant, Newborn; Male; Nit | 1995 |
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones.
Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniqu | 1995 |
Evidence of increased nitric oxide production in patients with the sepsis syndrome.
Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Female; Humans; Hypotension; Male; Middle Aged; | 1993 |
Failure of arginine-vasopressin and other pressor hormones to increase in severe recurrent dialysis hypotension.
Topics: Acute Disease; Administration, Inhalation; Adult; Aged; Arginine Vasopressin; Baroreflex; Blood Pres | 1995 |
Hypotension during hemodialysis: role for nitric oxide.
Topics: Adult; Aged; Humans; Hypotension; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Renal Dialysis; Ski | 1997 |
Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of endotoxic shock.
Topics: Adrenalectomy; Animals; Biopterins; Dexamethasone; Disease Models, Animal; Enzyme Induction; Escheri | 1997 |
Combined effects of dexamethasone and aminoguanidine on rats with endotoxemia.
Topics: Animals; Blood Pressure; Dexamethasone; Drug Interactions; Endotoxemia; Enzyme Inhibitors; Guanidine | 1998 |
Beneficial effects of tetramethylpyrazine, an active constituent of Chinese herbs, on rats with endotoxemia.
Topics: Animals; Blood Pressure; Endotoxemia; Heart Rate; Hypotension; In Vitro Techniques; Male; Medicine, | 1998 |
Enhanced production of nitric oxide may be involved in acute hypotension during maintenance hemodialysis.
Topics: Acute Disease; Anions; Blood Pressure; Cyclic GMP; Endothelin-1; Female; Heart Rate; Humans; Hypoten | 1998 |
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc | 1998 |
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidne | 1998 |
Viagra: beyond the jokes.
Topics: Cyclic GMP; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Nitrates; Phosphodie | 1998 |
Hypotension induced by exercise is associated with enhanced release of adenyl purines from aged rat artery.
Topics: Adenine Nucleotides; Adenosine; Aging; Animals; Arteries; Blood Pressure; Cholesterol; Fatty Acids; | 1999 |
Contribution of nitric oxide to exercise-induced hypotension in human sympathetic denervation.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Denervation; Exercise Test; Female; Heart Rate; H | 1999 |
Increased plasma adrenomedullin levels in hemodialysis patients with sustained hypotension.
Topics: Adrenomedullin; Adult; Blood Pressure; Blood Volume; Female; Humans; Hypotension; Interleukin-1; Iod | 2000 |
Managing sexual dysfunction. Using sildenafil for patients with cardiovascular disease. Heart and Stroke Foundation of Canada. Canadian Cardiovascular Society.
Topics: Cardiovascular Diseases; Contraindications; Erectile Dysfunction; Humans; Hypotension; Male; Nitrate | 2000 |
Role of nitric oxide in haemodialysis hypotension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; Middle Aged | 2000 |
Resistance to endotoxin shock in transgenic mice overexpressing endothelial nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Cyclic GMP; Edema; Female; Granulocytes; Hypotension; Immunity, Inna | 2000 |
Low temperature hemodialysis prevents hypote nsive episodes by reducingnitric oxide synthesis.
Topics: Aged; Body Weight; Female; Humans; Hypotension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; | 2000 |
Viagra presents special concerns for the hygienist and the dental team.
Topics: Chest Pain; Contraindications; Dental Care; Drug Interactions; Erectile Dysfunction; Humans; Hypoten | 1998 |
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
Topics: Aged; Angina Pectoris; Coronary Angiography; Diltiazem; Humans; Hypotension; Male; Nitrates; Phospho | 2000 |
Association of human hepatocyte growth factor with hemodialysis hypotension.
Topics: Blood Pressure; Female; Hepatocyte Growth Factor; Humans; Hypotension; Male; Middle Aged; Nitrates; | 2000 |
Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice.
Topics: Animals; Aorta, Thoracic; Bacterial Proteins; Blood Pressure; Body Temperature; Cells, Cultured; Esc | 2001 |
Reversible sequestration of nitric oxide by hemoglobin during hemodialysis in end-stage renal disease.
Topics: Anemia; Arginine; Erythropoietin; Hematocrit; Hemoglobins; Humans; Hypotension; Kidney Failure, Chro | 2001 |
Glutamate release via NO production evoked by NMDA in the NTS enhances hypotension and bradycardia in vivo.
Topics: Animals; Blood Pressure; Bradycardia; Calcium; Glutamic Acid; Heart Rate; Hypotension; Infusions, Pa | 2001 |
Peroxynitrite reduces vasodilatory responses to reduced intravascular pressure, calcitonin gene-related peptide, and cromakalim in isolated middle cerebral arteries.
Topics: Animals; Calcitonin Gene-Related Peptide; Cromakalim; Free Radicals; Hypotension; Male; Middle Cereb | 2001 |
Organ sites of lipopolysaccharide-induced nitric oxide production in the anesthetized rat.
Topics: Anesthesia, General; Animals; Blood Pressure; Female; Hypotension; Ileum; Intestinal Mucosa; Kinetic | 2001 |
Repeated administration of protamine does not attenuate circulatory changes caused by protamine reversal of heparin in dogs.
Topics: Animals; Anticoagulants; Dogs; Hemodynamics; Heparin; Heparin Antagonists; Hypertension, Pulmonary; | 2001 |
Potentiation of sildenafil-induced hypotension is minimal with nitrates generating a radical intermediate.
Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Free Radica | 2001 |
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
Topics: Aged; Cardiac Catheterization; Cardiovascular Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzym | 2001 |
Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies; Blood Pressure; Dansyl Compounds; Endotoxins; | 2001 |
Recombinant tissue factor pathway inhibitor prevents lipopolysaccharide-induced systemic hypotension in rats by inhibiting excessive production of nitric oxide.
Topics: Animals; Dansyl Compounds; Enzyme Induction; Enzyme Inhibitors; Factor VIIa; Factor Xa Inhibitors; G | 2001 |
Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats.
Topics: Animals; Antithrombin III; Disease Models, Animal; Endotoxins; Enzyme Induction; Epoprostenol; Human | 2002 |
Effective inhibition of nitric oxide production by aminoguanidine does not reverse hypotension in endotoxaemic rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Endotoxemia; Guanidines; Hypotension; Mal | 2002 |
Nifedipine-induced hypotension and mesenteric ischemia.
Topics: Adrenergic beta-Antagonists; Calcium Chloride; Drug Therapy, Combination; Hemodynamics; Humans; Hypo | 1989 |
Nitrate therapy in stable angina pectoris.
Topics: Angina Pectoris; Bradycardia; Humans; Hypotension; Nitrates; Nitroglycerin; Substance Withdrawal Syn | 1988 |
[The effect of isosorbide-dinitrate on pulmonary artery pressure in chronic pulmonary heart disease].
Topics: Administration, Oral; Aerosols; Aged; Blood Pressure; Brachial Artery; Catheterization; Chronic Dise | 1972 |
A comparison of the toxicology of triethylene glycol dinitrate and propylene glycol dinitrate.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Weight; Creatine Kinase; Diaphragm; | 1973 |