nitrates has been researched along with Hyperammonemia in 9 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Hyperammonemia: Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatic encephalopathy is seen as a clinical manifestation of a chronic low grade cerebral edema, which is thought to trigger disturbances of astrocyte function, glioneuronal communication, and finally HE symptoms." | 6.43 | Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy. ( Görg, B; Häussinger, D; Reinehr, R; Schliess, F, 2005) |
| "Hyperammonemia is a common finding in children with methylmalonic acidemia and propionic acidemia, but its contribution to the development of the neurological symptoms in the affected patients is poorly known." | 3.80 | Disruption of redox homeostasis and brain damage caused in vivo by methylmalonic acid and ammonia in cerebral cortex and striatum of developing rats. ( de Oliveira, FH; Grings, M; Hickmann, FH; Leipnitz, G; Monteiro, WO; Sitta, Â; Soares, LE; Viegas, CM; Wajner, M; Zanatta, Â, 2014) |
| "Cerebellar ataxia is commonly observed in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, an inherited metabolic disorder biochemically characterized by ornithine (Orn), homocitrulline (Hcit) and ammonia accumulation." | 3.79 | Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome. ( Busanello, EN; Grings, M; Leipnitz, G; Moura, AP; Tonin, AM; Viegas, CM; Wajner, M; Zanatta, A, 2013) |
| "Minimal hepatic encephalopathy (MHE) is common in cirrhosis but its pathophysiologic basis remains undefined." | 2.73 | Role of ammonia and inflammation in minimal hepatic encephalopathy. ( Jalan, R; Olde Damink, SW; Shawcross, DL; Wright, G, 2007) |
| "Hepatic encephalopathy is seen as a clinical manifestation of a chronic low grade cerebral edema, which is thought to trigger disturbances of astrocyte function, glioneuronal communication, and finally HE symptoms." | 2.43 | Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy. ( Görg, B; Häussinger, D; Reinehr, R; Schliess, F, 2005) |
| "LPS induced cytotoxic brain swelling and maintained anatomical integrity of the blood-brain barrier." | 1.34 | Endotoxemia produces coma and brain swelling in bile duct ligated rats. ( Brooks, HF; Davies, C; Davies, NA; Harry, D; Hodges, SJ; Jalan, R; Mani, AR; Moore, KP; Shawcross, DL; Stadlbauer, V; Williams, R; Wright, G; Zou, Z; Zwingmann, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurtz, CB | 1 |
| Millet, YA | 1 |
| Puurunen, MK | 1 |
| Perreault, M | 1 |
| Charbonneau, MR | 1 |
| Isabella, VM | 1 |
| Kotula, JW | 1 |
| Antipov, E | 1 |
| Dagon, Y | 1 |
| Denney, WS | 1 |
| Wagner, DA | 1 |
| West, KA | 1 |
| Degar, AJ | 1 |
| Brennan, AM | 1 |
| Miller, PF | 1 |
| Zanatta, A | 2 |
| Viegas, CM | 2 |
| Tonin, AM | 1 |
| Busanello, EN | 1 |
| Grings, M | 2 |
| Moura, AP | 1 |
| Leipnitz, G | 2 |
| Wajner, M | 2 |
| Hickmann, FH | 1 |
| Monteiro, WO | 1 |
| Soares, LE | 1 |
| Sitta, Â | 1 |
| de Oliveira, FH | 1 |
| ElMlili, N | 1 |
| Boix, J | 1 |
| Ahabrach, H | 1 |
| Rodrigo, R | 1 |
| Errami, M | 1 |
| Felipo, V | 1 |
| Bemeur, C | 1 |
| Desjardins, P | 1 |
| Butterworth, RF | 1 |
| Schliess, F | 2 |
| Foster, N | 1 |
| Görg, B | 2 |
| Reinehr, R | 2 |
| Häussinger, D | 2 |
| Shawcross, DL | 2 |
| Wright, G | 2 |
| Olde Damink, SW | 1 |
| Jalan, R | 2 |
| Davies, NA | 1 |
| Hodges, SJ | 1 |
| Zwingmann, C | 1 |
| Brooks, HF | 1 |
| Mani, AR | 1 |
| Harry, D | 1 |
| Stadlbauer, V | 1 |
| Zou, Z | 2 |
| Williams, R | 1 |
| Davies, C | 1 |
| Moore, KP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Therapeutic Effect of Rifaximin on Covert Hepatic Encephalopathy With Underlying Small Intestinal Bacterial Overgrowth and Gastrointestinal Dysmotility in Liver Cirrhosis Patients[NCT04244877] | Phase 3 | 0 participants (Actual) | Interventional | 2021-09-15 | Withdrawn (stopped due to Study was unable to recruit participants..) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nitrates and Hyperammonemia
| Article | Year |
|---|---|
Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy.
Topics: Animals; Brain; Cytokines; Free Radical Scavengers; Free Radicals; Hepatic Encephalopathy; Humans; H | 2010 |
Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy.
Topics: Animals; Astrocytes; Brain Chemistry; Hepatic Encephalopathy; Humans; Hyperammonemia; Nerve Tissue P | 2005 |
2 trials available for nitrates and Hyperammonemia
| Article | Year |
|---|---|
An engineered
Topics: Ammonia; Animals; Arginine; Biosynthetic Pathways; Disease Models, Animal; Escherichia coli; Feces; | 2019 |
Role of ammonia and inflammation in minimal hepatic encephalopathy.
Topics: Adult; Aged; Amino Acids; Ammonia; Biomarkers; C-Reactive Protein; Female; Hepatic Encephalopathy; H | 2007 |
5 other studies available for nitrates and Hyperammonemia
| Article | Year |
|---|---|
Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome.
Topics: Aconitate Hydratase; Animals; Cerebellum; Citrulline; Creatine Kinase; Electron Transport; Glutathio | 2013 |
Disruption of redox homeostasis and brain damage caused in vivo by methylmalonic acid and ammonia in cerebral cortex and striatum of developing rats.
Topics: Ammonia; Animals; Antioxidants; Catalase; Cerebral Cortex; Corpus Striatum; Fluoresceins; Glutathion | 2014 |
Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models, | 2010 |
Hypoosmotic swelling increases protein tyrosine nitration in cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Edema; Calcium Signaling; Calmodulin; Cell Size; Cells, | 2004 |
Endotoxemia produces coma and brain swelling in bile duct ligated rats.
Topics: Ammonia; Animals; Brain; Brain Edema; Capillaries; Cholestasis, Extrahepatic; Coma; Consciousness; C | 2007 |