nitrates has been researched along with Hemorrhagic Shock in 28 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 7.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| "However, results in hemorrhagic shock (HS) were controversial." | 5.39 | Effect of N-acetylcysteine (NAC) on acute lung injury and acute kidney injury in hemorrhagic shock. ( Jo, YH; Kim, K; Kwon, WY; Lee, JH; Rhee, JE; Rim, KP; Suh, GJ, 2013) |
| "In endotoxic and hemorrhagic shock and splanchic ischemia-reperfusion, dihydrorhodamine oxidation rapidly increased, which was prevented by inhibition of endothelial nitric oxide (." | 5.29 | Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury. ( Ischiropoulos, H; Salzman, AL; Szabó, C, 1995) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 3.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| " This paper compares survival rates and hemodynamic and metabolic effects of hypertonic NaCl with sodium salts (acetate, bicarbonate, and nitrate), chlorides [lithium and tris(hydroxymethyl)aminomethane (Tris)], and nonelectrolytes (glucose, mannitol, and urea) after severe hemorrhage (44." | 3.67 | Hyperosmotic sodium salts reverse severe hemorrhagic shock: other solutes do not. ( Negraes, GA; Nogueira da Silva, RI; Oliveira, MA; Rocha e Silva, M; Velasco, IT, 1987) |
| "However, results in hemorrhagic shock (HS) were controversial." | 1.39 | Effect of N-acetylcysteine (NAC) on acute lung injury and acute kidney injury in hemorrhagic shock. ( Jo, YH; Kim, K; Kwon, WY; Lee, JH; Rhee, JE; Rim, KP; Suh, GJ, 2013) |
| "Acute lung injury was associated with a higher degree of pulmonary HIF-1α and iNOS expression as well as apoptosis in the lungs." | 1.38 | Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats. ( Hu, R; Huang, Y; Jiang, H; Li, QF; Xu, H, 2012) |
| "Although trauma-hemorrhage produces tissue hypoxia, systemic inflammatory response and organ dysfunction, the mechanisms responsible for these alterations are not clear." | 1.35 | Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury. ( Bland, KI; Chaudry, IH; Choudhry, MA; Hsu, JT; Kan, WH; Raju, R; Schwacha, MG, 2008) |
| "Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental." | 1.35 | An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage. ( Barclay, D; Billiar, TR; Clermont, G; Ghuma, A; Gomez, H; Gordon, L; Hermus, L; Kim, HK; Namas, R; Ochoa, J; Peitzman, A; Pinsky, MR; Polanco, P; Puyana, JC; Rosengart, MR; Torres, A; Vodovotz, Y; Zamora, R; Zenker, S, 2009) |
| "Realizing that hemorrhagic shock induces nitric oxide overproduction in intact animals, we sought to explore whether glucocorticoids attenuate hemorrhagic shock-induced increases in intrapulmonary nitric oxide formation and whether they might do so by inhibiting the formation of tetrahydrobiopterin, iNOS protein, and CAT-2." | 1.32 | Dexamethasone suppresses iNOS yet induces GTPCH and CAT-2 mRNA expression in rat lungs. ( Haque, IU; Huang, CJ; Nasiroglu, O; Sarcia, PJ; Scumpia, PO; Skimming, JW; Stevens, BR; Wood, CE, 2003) |
| "Hemorrhagic shock is associated with early vasomotor paralysis as well as with early derangements in the cellular metabolic status." | 1.30 | Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock. ( Szabó, C, 1998) |
| "In endotoxic and hemorrhagic shock and splanchic ischemia-reperfusion, dihydrorhodamine oxidation rapidly increased, which was prevented by inhibition of endothelial nitric oxide (." | 1.29 | Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury. ( Ischiropoulos, H; Salzman, AL; Szabó, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 15 (53.57) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 5 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 2 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
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| Zager, RA | 1 |
| Johnson, ACM | 1 |
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| Zhang, Y | 6 |
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| Wang, Y | 7 |
| Zhao, R | 1 |
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| Barrett, HE | 1 |
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| de Jong, M | 1 |
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| Wachter, H | 1 |
| Redl, H | 1 |
| Schlag, G | 1 |
| Pannen, BH | 1 |
| Nöldge-Schomburg, GF | 1 |
| Zhang, JX | 1 |
| Robotham, JL | 1 |
| Clemens, MG | 1 |
| Geiger, KK | 1 |
| Zingarelli, B | 2 |
| Rubanyi, GM | 1 |
| Hua, TC | 2 |
| Scott, GS | 1 |
| Hake, P | 1 |
| Zhao, KS | 1 |
| Yang, GY | 1 |
| Jin, C | 1 |
| Huang, Q | 1 |
| Rocha e Silva, M | 1 |
| Velasco, IT | 1 |
| Nogueira da Silva, RI | 1 |
| Oliveira, MA | 2 |
| Negraes, GA | 1 |
2 reviews available for nitrates and Hemorrhagic Shock
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Nitric oxide and circulatory shock.
Topics: Animals; Humans; Microcirculation; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synth | 1998 |
1 trial available for nitrates and Hemorrhagic Shock
26 other studies available for nitrates and Hemorrhagic Shock
| Article | Year |
|---|---|
Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.
Topics: Amidines; Animals; Benzylamines; Blood Pressure; Chemokines; Cytokines; Disease Models, Animal; Enzy | 2008 |
An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.
Topics: Animals; Disease Models, Animal; Female; Humans; Inflammation; Male; Middle Aged; Nitrates; Nitrites | 2009 |
A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks.
Topics: Animals; Cluster Analysis; Inflammation; Interleukin-10; Interleukin-6; Male; Mice; Mice, Inbred C57 | 2011 |
Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats.
Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cytoprotection; Disease Models, Animal; | 2012 |
Physiologic responses to severe hemorrhagic shock and the genesis of cardiovascular collapse: can irreversibility be anticipated?
Topics: Animals; Autonomic Nervous System; Blood Pressure; Catecholamines; Cytokines; Disease Models, Animal | 2012 |
Effect of N-acetylcysteine (NAC) on acute lung injury and acute kidney injury in hemorrhagic shock.
Topics: Acetylcysteine; Acute Kidney Injury; Acute Lung Injury; Animals; Arterial Pressure; Glucose; I-kappa | 2013 |
Dexamethasone suppresses iNOS yet induces GTPCH and CAT-2 mRNA expression in rat lungs.
Topics: Administration, Inhalation; Animals; Base Sequence; Blood Pressure; Cationic Amino Acid Transporter | 2003 |
The role of inducible nitric oxide synthase inhibitor on the arteriolar hyporesponsiveness in hemorrhagic-shocked rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; | 2003 |
Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage.
Topics: Anabolic Agents; Androstenediol; Animals; Cardiac Output; Interleukin-6; Laparotomy; Male; Nitrates; | 2004 |
Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; | 2004 |
Hemorrhagic shock in swine: nitric oxide and potassium sensitive adenosine triphosphate channel activation.
Topics: Animals; Aorta, Thoracic; ATP-Binding Cassette Transporters; Carotid Arteries; Hemodynamics; In Vitr | 2004 |
Nitrosyl heme production compared in endotoxemic and hemorrhagic shock.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Electr | 2005 |
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.
Topics: Acetophenones; Alanine Transaminase; Animals; Creatinine; DNA; Enzyme Inhibitors; Humans; Intestinal | 2005 |
The role of selective nitric oxide synthase inhibitor on nitric oxide and PGE2 levels in refractory hemorrhagic-shocked rats.
Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Brain; Creatinine; Cyclooxygenase 2; Cyclooxyg | 2005 |
Methemoglobinemia misdiagnosed as ruptured ectopic pregnancy.
Topics: Adult; Antidotes; Antioxidants; Ascorbic Acid; Blood Gas Analysis; Diagnosis, Differential; Female; | 2005 |
p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
Topics: Abdomen; Animals; Calmodulin; Cardiotonic Agents; Caveolin 1; Chemokine CXCL1; Chemokine CXCL2; Dise | 2008 |
Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury.
Topics: Animals; Male; Nitrates; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury; Rhodamines; Sh | 1995 |
Pteridine and nitrite/nitrate formation in experimental septic and traumatic shock.
Topics: Animals; Arteries; Cardiac Output; Creatinine; Disease Models, Animal; Escherichia coli Infections; | 1996 |
Regulation of hepatic blood flow during resuscitation from hemorrhagic shock: role of NO and endothelins.
Topics: Animals; Bosentan; Endothelins; Hemodynamics; Liver Circulation; Male; Nitrates; Nitric Oxide; Nitri | 1997 |
Amelioration by mercaptoethylguanidine of the vascular and energetic failure in haemorrhagic shock in the anesthetised rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Guanidine; Isotonic Solutions; Male; Models, Biological; Nitr | 1997 |
Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock.
Topics: Animals; Blood Pressure; Cell Nucleus; Death; Disease Models, Animal; DNA Damage; Male; Models, Biol | 1998 |
Influence of L-arginine, aminoguanidine, and NG-nitro-L-arginine methyl ester (L-name) on the survival rate in a rat model of hemorrhagic shock.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Creatinine; Dinoprostone; Disease Mo | 1999 |
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Topics: Animals; Antioxidants; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema | 2000 |
Role of nitric oxide in hemorrhagic shock-induced bacterial translocation.
Topics: Animals; Bacterial Translocation; Blood Pressure; Enzyme Inhibitors; Guanidines; Male; NG-Nitroargin | 2000 |
Peroxynitrite leads to arteriolar smooth muscle cell membrane hyperpolarization and low vasoreactivity in severe shock.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Arterioles; Charybdotoxin | 2000 |
Hyperosmotic sodium salts reverse severe hemorrhagic shock: other solutes do not.
Topics: Acetates; Acetic Acid; Animals; Bicarbonates; Blood Gas Analysis; Blood Pressure; Cardiac Output; Ch | 1987 |