nitrates has been researched along with Glaucoma in 13 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of the L-arginine-nitric oxide (NO) pathway in aqueous humour dynamics by measuring nitrate, nitrite and cyclic (cGMP) levels in guanosine 3',5'-monophosphate the aqueous humour of glaucomatous and nonglaucomatous cataract patients." | 7.71 | Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients. ( Aine, E; Kotikoski, H; Moilanen, E; Vapaatalo, H, 2002) |
| "1) inhibitor dorzolamide (DRZ), a new sulfonamide CA inhibitor also incorporating NO-donating moieties, NCX250, and isosorbide mononitrate (ISMN) (an NO-donating compound with no CA inhibitory properties) were investigated for their intraocular pressure (IOP) lowering effects in rabbits with carbomer-induced glaucoma." | 3.78 | A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology. ( Fabrizi, F; Galassi, F; Impagnatiello, F; Masini, E; Mincione, F; Scozzafava, G; Somma, T; Supuran, CT, 2012) |
| "The IOP lowering effects of NCX 139, a new chemical entity comprising latanoprost amide and a NO-donating moiety, were compared to those of the respective des-nitro analog in in vitro assays and in rabbit and dog models of ocular hypertension." | 3.77 | A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs. ( Batugo, M; Borghi, V; Brambilla, S; Carreiro, ST; Chiroli, V; Chong, WK; Gale, DC; Guzzetta, M; Impagnatiello, F; Krauss, AH; Ongini, E; Prasanna, G, 2011) |
| "To study the role of the L-arginine-nitric oxide (NO) pathway in aqueous humour dynamics by measuring nitrate, nitrite and cyclic (cGMP) levels in guanosine 3',5'-monophosphate the aqueous humour of glaucomatous and nonglaucomatous cataract patients." | 3.71 | Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients. ( Aine, E; Kotikoski, H; Moilanen, E; Vapaatalo, H, 2002) |
| "Glaucoma is a progressive optic neuropathy and is the leading cause of blindness in the United States and other industrialized countries." | 2.44 | Oxidative and nitrative stress markers in glaucoma. ( Aslan, M; Cort, A; Yucel, I, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Impagnatiello, F | 2 |
| Borghi, V | 1 |
| Gale, DC | 1 |
| Batugo, M | 1 |
| Guzzetta, M | 1 |
| Brambilla, S | 1 |
| Carreiro, ST | 1 |
| Chong, WK | 1 |
| Prasanna, G | 1 |
| Chiroli, V | 1 |
| Ongini, E | 1 |
| Krauss, AH | 1 |
| Fabrizi, F | 1 |
| Mincione, F | 1 |
| Somma, T | 1 |
| Scozzafava, G | 1 |
| Galassi, F | 1 |
| Masini, E | 1 |
| Supuran, CT | 1 |
| WHITWORTH, CG | 1 |
| GRANT, WM | 1 |
| DAYTON, GO | 1 |
| Aslan, M | 1 |
| Cort, A | 1 |
| Yucel, I | 1 |
| Kotikoski, H | 1 |
| Moilanen, E | 1 |
| Vapaatalo, H | 1 |
| Aine, E | 1 |
| Robertson, D | 1 |
| Stevens, RM | 1 |
| Gol'dovskaia, IL | 1 |
| Fujie, S | 1 |
| Hirosawa, K | 1 |
| Wisznia, KI | 1 |
| Lazar, M | 1 |
| Leopold, IH | 1 |
| Alter, HG | 1 |
| Yamashita, S | 1 |
| Toyomasu, N | 1 |
1 review available for nitrates and Glaucoma
| Article | Year |
|---|---|
Oxidative and nitrative stress markers in glaucoma.
Topics: Biomarkers; Glaucoma; Humans; Nitrates; Oxidative Stress | 2008 |
1 trial available for nitrates and Glaucoma
| Article | Year |
|---|---|
[Clinical experiences with 70 per cent isosorbide].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Furans; Glaucoma; Glycerol; Humans; Intra | 1968 |
11 other studies available for nitrates and Glaucoma
| Article | Year |
|---|---|
Dietary nitrate may lower risk of glaucoma.
Topics: Diet; Glaucoma; Humans; Nitrates; Risk | 2016 |
A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs.
Topics: Amides; Animals; Antihypertensive Agents; Aorta; Bimatoprost; Chromatography, High Pressure Liquid; | 2011 |
A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology.
Topics: Acrylic Resins; Animals; Carbonic Anhydrases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glauc | 2012 |
USE OF NITRATE AND NITRITE VASODILATORS BY GLAUCOMATOUS PATIENTS.
Topics: Angina Pectoris; Glaucoma; Humans; Nitrates; Nitrites; Nitroglycerin; Toxicology; Vasodilator Agents | 1964 |
GLAUCOMA DUE TO CLOSURE OF THE ANGLE OF THE ANTERIOR CHAMBER.
Topics: Acetazolamide; Anterior Chamber; Aqueous Humor; Blindness; Diagnosis; Glaucoma; Gonioscopy; Humans; | 1964 |
Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients.
Topics: Aged; Aqueous Humor; Arginine; Biomarkers; Blood Pressure; Cataract; Cyclic GMP; Female; Glaucoma; H | 2002 |
Nitrates and glaucoma.
Topics: Glaucoma; Humans; Nitrates | 1977 |
[Use of nitrates in patients with glaucoma].
Topics: Adult; Glaucoma; Humans; Hypertension; Intraocular Pressure; Middle Aged; Nitrates | 1988 |
[Is nitrates contraindication for the angina pectoris patients complicated with glaucoma?].
Topics: Aged; Angina Pectoris; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Nitrates | 1987 |
Oral isosorbide and intraocular pressure.
Topics: Administration, Oral; Back Pain; Chromatography, Gas; Diarrhea; Diuretics; Furans; Glaucoma; Headach | 1970 |
[Which drugs can cause glaucoma?].
Topics: Caffeine; Central Nervous System Stimulants; Drug-Related Side Effects and Adverse Reactions; Epinep | 1970 |