nitrates has been researched along with Glaucoma, Suspect in 5 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The IOP lowering effects of NCX 139, a new chemical entity comprising latanoprost amide and a NO-donating moiety, were compared to those of the respective des-nitro analog in in vitro assays and in rabbit and dog models of ocular hypertension." | 3.77 | A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs. ( Batugo, M; Borghi, V; Brambilla, S; Carreiro, ST; Chiroli, V; Chong, WK; Gale, DC; Guzzetta, M; Impagnatiello, F; Krauss, AH; Ongini, E; Prasanna, G, 2011) |
| " Its Phase 3 pivotal clinical trials failed at the wrong dose and dosing regimen because of the misinterpretation of the complex IOP results from the Phase 2 monotherapy and combination studies." | 2.72 | Trabodenoson on trabecular meshwork rejuvenation: a comprehensive review of clinical data. ( Qiu, TG, 2021) |
| "Ocular hypertension was induced by unilaterally cauterizing three episcleral vessels and the unoperated eye served as control." | 1.37 | Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. ( Aslan, M; Batinic-Haberle, I; Cort, A; Dogan, S; Ozturk, N; Spasojevic, I; Unal, M; Yargicoglu, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qiu, TG | 1 |
| Khawaja, AP | 1 |
| Chan, MP | 1 |
| Broadway, DC | 1 |
| Garway-Heath, DF | 1 |
| Luben, R | 1 |
| Yip, JL | 1 |
| Hayat, S | 1 |
| Wareham, NJ | 1 |
| Khaw, KT | 1 |
| Foster, PJ | 1 |
| Myers, JS | 1 |
| Sall, KN | 1 |
| DuBiner, H | 1 |
| Slomowitz, N | 1 |
| McVicar, W | 1 |
| Rich, CC | 1 |
| Baumgartner, RA | 1 |
| Impagnatiello, F | 1 |
| Borghi, V | 1 |
| Gale, DC | 1 |
| Batugo, M | 1 |
| Guzzetta, M | 1 |
| Brambilla, S | 1 |
| Carreiro, ST | 1 |
| Chong, WK | 1 |
| Prasanna, G | 1 |
| Chiroli, V | 1 |
| Ongini, E | 1 |
| Krauss, AH | 1 |
| Dogan, S | 1 |
| Unal, M | 1 |
| Ozturk, N | 1 |
| Yargicoglu, P | 1 |
| Cort, A | 1 |
| Spasojevic, I | 1 |
| Batinic-Haberle, I | 1 |
| Aslan, M | 1 |
1 review available for nitrates and Glaucoma, Suspect
| Article | Year |
|---|---|
Trabodenoson on trabecular meshwork rejuvenation: a comprehensive review of clinical data.
Topics: Animals; Drug Delivery Systems; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Nitrates; Ocular | 2021 |
1 trial available for nitrates and Glaucoma, Suspect
| Article | Year |
|---|---|
A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Fema | 2016 |
3 other studies available for nitrates and Glaucoma, Suspect
| Article | Year |
|---|---|
Systemic medication and intraocular pressure in a British population: the EPIC-Norfolk Eye Study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aspirin; Biguanides; Blood Pressure; Body Mass | 2014 |
A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs.
Topics: Amides; Animals; Antihypertensive Agents; Aorta; Bimatoprost; Chromatography, High Pressure Liquid; | 2011 |
Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats.
Topics: Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Electrophoresis, Polyacrylamide Ge | 2011 |