Page last updated: 2024-10-19

nitrates and Fetal Growth Restriction

nitrates has been researched along with Fetal Growth Restriction in 13 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
" Exposure to drinking-water atrazine metabolites/nitrate mixture was divided into 6 classes according to the presence or absence of atrazine metabolites and to terciles of nitrate concentrations in each trimester of pregnancy."3.79Drinking-water exposure to a mixture of nitrate and low-dose atrazine metabolites and small-for-gestational age (SGA) babies: a historic cohort study. ( Albouy-Llaty, M; Carles, C; Dupuis, A; Limousi, F; Migeot, V; Rabouan, S; Strezlec, S, 2013)
" Whilst mechanisms underpinning impaired uteroplacental vascular function are not fully understood, interventions aimed at enhancing nitric oxide (NO) bioavailability remain a key area of interest in obstetric research."2.55Dietary interventions for fetal growth restriction - therapeutic potential of dietary nitrate supplementation in pregnancy. ( Cottrell, E; Greenwood, S; Johnstone, E; Myers, J; Ormesher, L; Sibley, C; Tropea, T; Wareing, M, 2017)
"Research on the pathogenesis of preeclampsia in several studies has established the involvement of the NO-system in preeclampsia and fetal intrauterine growth restriction (IUGR)."1.33Plasma- and urine concentrations of nitrite/nitrate and cyclic Guanosinemonophosphate in intrauterine growth restricted and preeclamptic pregnancies. ( Bidlingmaier, M; Friese, K; Jeschke, U; Kainer, F; Mylonas, I; Schiessl, B; Strasburger, C, 2006)
" The higher nitrate exposure categories were positively associated with intrauterine growth restriction and prematurity, and significant dose-response trends were seen, even after adjustment for several important covariates."1.31Agricultural contamination of groundwater as a possible risk factor for growth restriction or prematurity. ( Bryanton, J; Bukowski, J; Somers, G, 2001)
"In contrast, in preeclampsia and/or intrauterine growth restriction, moderate to intense nitrotyrosine immunostaining was seen in villous vascular endothelium, and immunostaining was also seen in surrounding vascular smooth muscle and villous stroma."1.29Nitrotyrosine residues in placenta. Evidence of peroxynitrite formation and action. ( Brockman, DE; Eis, AL; Greer, I; Lyall, F; Myatt, L; Rosenfield, RB, 1996)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Jensen, AS2
Coffman, VR2
Schullehner, J2
Trabjerg, BB2
Pedersen, CB2
Hansen, B2
Olsen, J2
Pedersen, M2
Stayner, LT2
Sigsgaard, T2
Ramos Gonzalez, M1
DeConne, TM1
Travis, OK1
Baik, C1
Tardo, GA1
Amaral, L1
Jackson, C1
Greer, M1
Giachelli, C1
Ibrahim, T1
Herrock, OT1
Williams, JM1
Cornelius, DC1
Schaumburg, I1
Tsikas, D1
Bollenbach, A1
Savvidou, MD1
Cottrell, E1
Tropea, T1
Ormesher, L1
Greenwood, S1
Wareing, M1
Johnstone, E1
Myers, J1
Sibley, C1
Migeot, V1
Albouy-Llaty, M1
Carles, C1
Limousi, F1
Strezlec, S1
Dupuis, A1
Rabouan, S1
Schiessl, B1
Strasburger, C1
Bidlingmaier, M1
Mylonas, I1
Jeschke, U1
Kainer, F1
Friese, K1
Myatt, L1
Rosenfield, RB1
Eis, AL1
Brockman, DE1
Greer, I1
Lyall, F1
Miller, MJ1
Voelker, CA1
Olister, S1
Thompson, JH1
Zhang, XJ1
Rivera, D1
Eloby-Childress, S1
Liu, X1
Clark, DA1
Pierce, MR1
Greenberg, SS1
Lancaster, JR1
Xie, J1
Sarphie, TG1
Zhao, X1
Hua, L1
Freeman, T1
Kapusta, DR1
Giles, TD1
Powers, DR1
Bukowski, J1
Somers, G1
Bryanton, J1
Litvinov, NN1
Kazachkov, VI1
Astakhova, LF1
Gasimova, ZM1
Zhurkov, VS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy L-arginine + L-citrulline as a Dietary Supplement vs Placebo for Weight Gain in Fetus With a Decrease in Their Growth Curve in the Third Trimester of Pregnancy[NCT05029778]Phase 441 participants (Anticipated)Interventional2021-10-20Not yet recruiting
First-trimester Placental Ultrasound Study (First PLUS): an Observational Cohort Study to Assess the Clinical Utility of the OxNNet Toolkit for the Prediction of Adverse Pregnancy Outcomes.[NCT05326191]4,000 participants (Actual)Observational2022-03-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nitrates and Fetal Growth Restriction

ArticleYear
Dietary interventions for fetal growth restriction - therapeutic potential of dietary nitrate supplementation in pregnancy.
    The Journal of physiology, 2017, 08-01, Volume: 595, Issue:15

    Topics: Animals; Diet; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Maternal Nutritional P

2017
Dietary interventions for fetal growth restriction - therapeutic potential of dietary nitrate supplementation in pregnancy.
    The Journal of physiology, 2017, 08-01, Volume: 595, Issue:15

    Topics: Animals; Diet; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Maternal Nutritional P

2017
Dietary interventions for fetal growth restriction - therapeutic potential of dietary nitrate supplementation in pregnancy.
    The Journal of physiology, 2017, 08-01, Volume: 595, Issue:15

    Topics: Animals; Diet; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Maternal Nutritional P

2017
Dietary interventions for fetal growth restriction - therapeutic potential of dietary nitrate supplementation in pregnancy.
    The Journal of physiology, 2017, 08-01, Volume: 595, Issue:15

    Topics: Animals; Diet; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Maternal Nutritional P

2017

Other Studies

12 other studies available for nitrates and Fetal Growth Restriction

ArticleYear
Prenatal exposure to tap water containing nitrate and the risk of small-for-gestational-age: A nationwide register-based study of Danish births, 1991-2015.
    Environment international, 2023, Volume: 174

    Topics: Child; Denmark; Drinking Water; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Maternal

2023
Saying NO to fetal growth restriction: Implications for beetroot juice and melatonin.
    The Journal of physiology, 2020, Volume: 598, Issue:24

    Topics: Animals; Beta vulgaris; Blood Pressure; Female; Fetal Growth Retardation; Melatonin; Mice; Nitrates;

2020
Adoptive transfer of placental ischemia-stimulated natural killer cells causes a preeclampsia-like phenotype in pregnant rats.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2021, Volume: 85, Issue:6

    Topics: Adoptive Transfer; Animals; Cyclic GMP; Cytokines; Female; Fetal Growth Retardation; Ischemia; Kille

2021
Prenatal Exposure to Nitrate from Drinking Water and Markers of Fetal Growth Restriction: A Population-Based Study of Nearly One Million Danish-Born Children.
    Environmental health perspectives, 2021, Volume: 129, Issue:2

    Topics: Birth Weight; Child; Denmark; Drinking Water; Female; Fetal Growth Retardation; Humans; Nitrates; Pr

2021
Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
    Amino acids, 2018, Volume: 50, Issue:2

    Topics: Adult; Arginine; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Fetus; Gestational Age;

2018
Drinking-water exposure to a mixture of nitrate and low-dose atrazine metabolites and small-for-gestational age (SGA) babies: a historic cohort study.
    Environmental research, 2013, Volume: 122

    Topics: Adult; Atrazine; Cohort Studies; Drinking Water; Environmental Exposure; Female; Fetal Growth Retard

2013
Plasma- and urine concentrations of nitrite/nitrate and cyclic Guanosinemonophosphate in intrauterine growth restricted and preeclamptic pregnancies.
    Archives of gynecology and obstetrics, 2006, Volume: 274, Issue:3

    Topics: Birth Weight; Cyclic GMP; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Nitrates; Nitri

2006
Nitrotyrosine residues in placenta. Evidence of peroxynitrite formation and action.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:3

    Topics: Adult; Drug Residues; Female; Fetal Growth Retardation; Humans; Immunohistochemistry; Nitrates; Plac

1996
Fetal growth retardation in rats may result from apoptosis: role of peroxynitrite.
    Free radical biology & medicine, 1996, Volume: 21, Issue:5

    Topics: Animals; Apoptosis; Base Sequence; DNA Primers; Endotoxins; Enzyme Inhibitors; Female; Fetal Growth

1996
Effects of NO synthase inhibitors, arginine-deficient diet, and amiloride in pregnant rats.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2

    Topics: Abnormalities, Drug-Induced; Amiloride; Analysis of Variance; Animals; Arginine; Female; Fetal Death

1997
Agricultural contamination of groundwater as a possible risk factor for growth restriction or prematurity.
    Journal of occupational and environmental medicine, 2001, Volume: 43, Issue:4

    Topics: Agriculture; Case-Control Studies; Dose-Response Relationship, Drug; Female; Fetal Growth Retardatio

2001
[Benzol and lead nitrate as modifiers of the embryotoxic effect of cadmium chloride].
    Gigiena i sanitariia, 1991, Issue:1

    Topics: Animals; Benzene; Cadmium; Cadmium Chloride; Dose-Response Relationship, Drug; Drug Synergism; Femal

1991