Page last updated: 2024-10-19

nitrates and Esophageal Varices

nitrates has been researched along with Esophageal Varices in 20 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Research Excerpts

ExcerptRelevanceReference
"Based on low-certainty evidence, beta-blockers, variceal band ligation, sclerotherapy, and beta-blockers plus nitrates may decrease mortality compared to no intervention in people with high-risk oesophageal varices in people with cirrhosis and no previous history of bleeding."5.12Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta-analysis. ( Arunan, S; Begum, T; Benmassaoud, A; Best, LM; Cooper, NJ; Csenar, M; Davidson, BR; Freeman, SC; Gurusamy, KS; Iogna Prat, L; Milne, EJ; Pavlov, CS; Plaz Torres, MC; Roberts, D; Roccarina, D; Sutton, AJ; Tapp, M; Tsochatzis, E; Williams, NR, 2021)
"About 15% to 20% of oesophageal varices bleed in about one to three years of diagnosis."2.72Secondary prevention of variceal bleeding in adults with previous oesophageal variceal bleeding due to decompensated liver cirrhosis: a network meta-analysis. ( Arunan, S; Begum, T; Benmassaoud, A; Best, LM; Cooper, NJ; Csenar, M; Davidson, BR; Freeman, SC; Fritche, D; Gurusamy, KS; Iogna Prat, L; Milne, EJ; Pavlov, CS; Plaz Torres, MC; Roberts, D; Roccarina, D; Sutton, AJ; Tapp, M; Tsochatzis, E; Williams, NR, 2021)
"About 15% to 20% of oesophageal varices bleed within about one to three years after diagnosis."2.72Treatment for bleeding oesophageal varices in people with decompensated liver cirrhosis: a network meta-analysis. ( Arunan, S; Begum, T; Best, LM; Cooper, NJ; Csenar, M; Davidson, BR; Freeman, SC; Gurusamy, KS; Milne, EJ; Pavlov, CS; Roberts, D; Sutton, AJ; Tapp, M; Tsochatzis, E; Walshaw, D; Williams, NR, 2021)
"Recent advances in the pharmacologic treatment of portal hypertension have mainly focused on modifying an increased intrahepatic resistance through nitric oxide and/or modulation of vasoactive substances."2.61Pharmacologic Management of Portal Hypertension. ( Bunchorntavakul, C; Reddy, KR, 2019)
"In conclusion, chronic administration of organic nitrates, allowing for a nitrate-free interval each day, to cirrhotic patients reduces portal pressure with a variable, dose-dependent effect on azygos blood flow."2.39Organic nitrates in portal hypertension. ( Hayes, PC; Jones, AL, 1994)
"The prevalence of large esophageal varices was 20%."1.30Predictors of large esophageal varices in patients with cirrhosis. ( Boyer, TD; Carey, M; Chalasani, N; Imperiale, TF; Ismail, A; Kwo, PY; Madichetty, H; Sood, G; Wilcox, CM, 1999)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's4 (20.00)18.2507
2000's9 (45.00)29.6817
2010's3 (15.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Bunchorntavakul, C1
Reddy, KR1
Plaz Torres, MC2
Best, LM3
Freeman, SC3
Roberts, D3
Cooper, NJ3
Sutton, AJ3
Roccarina, D2
Benmassaoud, A2
Iogna Prat, L2
Williams, NR3
Csenar, M3
Fritche, D1
Begum, T3
Arunan, S3
Tapp, M3
Milne, EJ3
Pavlov, CS3
Davidson, BR3
Tsochatzis, E3
Gurusamy, KS3
Walshaw, D1
Mustafa, MZ1
Stanley, A1
Augustin, S1
González, A1
Badia, L1
Millán, L1
Gelabert, A1
Romero, A1
Segarra, A1
Martell, M1
Esteban, R1
Guardia, J1
Genescà, J1
Groszmann, RJ1
Garcia-Tsao, G1
Arkenau, HT1
Stichtenoth, DO1
Frölich, JC1
Manns, MP1
Böker, KH1
Imperiale, TF2
Chalasani, N2
Klein, RW1
Targownik, LE1
Spiegel, BM1
Dulai, GS1
Karsan, HA1
Gralnek, IM1
Rockey, DC1
Jones, AL1
Hayes, PC1
El-Newihi, HM1
Kanji, VK1
Mihas, AA1
Lebrec, D1
Ismail, A1
Sood, G1
Carey, M1
Wilcox, CM1
Madichetty, H1
Kwo, PY1
Boyer, TD1
Sanyal, AJ1
Angelico, M1
Lionetti, R1
Lowe, RC1
Grace, ND1
Vogt, W1
Fleig, WE1

Reviews

13 reviews available for nitrates and Esophageal Varices

ArticleYear
Pharmacologic Management of Portal Hypertension.
    Clinics in liver disease, 2019, Volume: 23, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anticoagulants; Antihypertensi

2019
Secondary prevention of variceal bleeding in adults with previous oesophageal variceal bleeding due to decompensated liver cirrhosis: a network meta-analysis.
    The Cochrane database of systematic reviews, 2021, 03-30, Volume: 3

    Topics: Adrenergic beta-2 Receptor Antagonists; Adult; Bias; Esophageal and Gastric Varices; Gastrointestina

2021
Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta-analysis.
    The Cochrane database of systematic reviews, 2021, 04-06, Volume: 4

    Topics: Adrenergic beta-Antagonists; Bias; Combined Modality Therapy; Drug Therapy, Combination; Esophageal

2021
Treatment for bleeding oesophageal varices in people with decompensated liver cirrhosis: a network meta-analysis.
    The Cochrane database of systematic reviews, 2021, 04-10, Volume: 4

    Topics: Adult; Bayes Theorem; Bias; Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointesti

2021
Variceal rebleeding: use of drug therapy and endoscopic band ligation.
    Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:2

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Drug Therapy, Combination; Endoscopy, Gastro

2014
Endoscopic variceal banding vs. pharmacological therapy for the prevention of recurrent variceal hemorrhage: what makes the difference?
    Gastroenterology, 2002, Volume: 123, Issue:4

    Topics: Adrenergic beta-Antagonists; Endoscopy; Esophageal and Gastric Varices; Humans; Nitrates; Secondary

2002
Pharmacologic therapy for gastrointestinal bleeding due to portal hypertension and esophageal varices.
    Current gastroenterology reports, 2006, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Algorithms; Antihypertensive Agents; Cardiovascular Agents; Esophageal

2006
Organic nitrates in portal hypertension.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:1

    Topics: Animals; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans

1994
Review: pharmacotherapeutic agents in the treatment of portal hypertension.
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:2

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Forecasting; Gastrointestinal Hemorrhag

1997
Long-acting nitrates in portal hypertension: to be or not to be?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:3

    Topics: Adrenergic beta-Antagonists; Delayed-Action Preparations; Esophageal and Gastric Varices; Female; Ga

2001
Primary prophylaxis of variceal hemorrhage.
    Clinics in liver disease, 2001, Volume: 5, Issue:3

    Topics: Adrenergic beta-Antagonists; Endoscopy; Esophageal and Gastric Varices; Hemorrhage; Humans; Hyperten

2001
[The patient with hematemesis. What to do?].
    Praxis, 2002, Mar-20, Volume: 91, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Electrocoagulation; Emergencies; Endos

2002
Pharmacological methods for the prevention of first and recurrent bleeding from esophagogastric varices.
    Zeitschrift fur Gastroenterologie, 1988, Volume: 26 Suppl 2

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Esophageal and Gastric Varices; Gastrointesti

1988

Other Studies

7 other studies available for nitrates and Esophageal Varices

ArticleYear
Long-term follow-up of hemodynamic responders to pharmacological therapy after variceal bleeding.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Esophageal and Gastric Varices; Female; Follow-Up Studies;

2012
Elevated nitric oxide levels in patients with chronic liver disease and cirrhosis correlate with disease stage and parameters of hyperdynamic circulation.
    Zeitschrift fur Gastroenterologie, 2002, Volume: 40, Issue:11

    Topics: Ascites; Data Interpretation, Statistical; Esophageal and Gastric Varices; Hemodynamics; Hepatitis,

2002
Measuring the hemodynamic response to primary pharmacoprophylaxis of variceal bleeding: a cost-effectiveness analysis.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:12

    Topics: Adrenergic beta-Antagonists; Cost-Benefit Analysis; Decision Trees; Esophageal and Gastric Varices;

2003
The cost-effectiveness of hepatic venous pressure gradient monitoring in the prevention of recurrent variceal hemorrhage.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:7

    Topics: Adrenergic beta-Antagonists; Blood Pressure Determination; Cost-Benefit Analysis; Endoscopy, Digesti

2004
Activity of gastric mucosal nitric oxide synthase in portal hypertensive gastropathy.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:3

    Topics: Adult; Aged; Esophageal and Gastric Varices; Gastric Mucosa; Humans; Hypertension, Portal; Liver Cir

1996
Predictors of large esophageal varices in patients with cirrhosis.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Adrenergic beta-Antagonists; Cohort Studies; Confidence Intervals; Cost-Benefit Analysis; Costs and

1999
Hepatic venous pressure gradient: to measure or not to measure, that is the question.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:5

    Topics: Adrenergic beta-Antagonists; Drug Synergism; Esophageal and Gastric Varices; Hemorrhage; Hepatic Vei

2000