nitrates has been researched along with Endotoxemia in 77 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
Excerpt | Relevance | Reference |
---|---|---|
"To investigate the systemic, pulmonary, and hepatosplanchnic hemodynamic and metabolic effects of delayed treatment with ethyl pyruvate in a long-term porcine model of hyperdynamic endotoxemia." | 7.73 | Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia. ( Albicini, M; Asfar, P; Bracht, H; Brückner, UB; Ehrmann, U; Fink, MP; Hauser, B; Kick, J; Radermacher, P; Vogt, J; Wachter, U, 2005) |
"Effect of ornithine which is known to inhibit L-arginine uptake via cationic amino acid transport system has been tested, and compared to aminoguanidine, an iNOS inhibitor in lypopolysaccharide (LPS)-induced endotoxemia in rats." | 7.72 | Effect of ornithine on the ileal histology, nitric oxide production and lipid peroxidation in LPS-induced endotoxemia. ( Aydin, S; Büyükafşar, K; Caglikülekçi, M; Cinel, I; Cinel, L; Dirlik, M; Oral, U; Tamer, L, 2003) |
"We studied the effects of administrating the nitric oxide synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME), or the nitric oxide precursor, L-arginine, on hemodynamic variables and serum nitrate concentrations in an anesthetized ovine model of endotoxemia to assess the effects on regional visceral blood flow and to determine whether L-arginine availability limits nitric oxide production." | 7.69 | L-arginine augments nitric oxide production and mesenteric blood flow in ovine endotoxemia. ( Allman, KG; Kennedy, MM; Stoddart, AP; Young, JD, 1996) |
"Endotoxemia was associated with renal dysfunctions as indicated by decreases in renal blood flow, urinary potassium excretion, and renal nitrate clearance." | 5.33 | N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia. ( Chiao, CW; Lee, SS; Su, MJ; Wu, CC, 2006) |
"Endotoxemia was induced in male rats by the intravenous injection of Salmonella typhosa lipopolysaccharide (LPS; 2 mg/kg/i." | 5.32 | Cloricromene in endotoxemia: role of NF-kappaB. ( Di Meglio, P; Di Rosa, M; di Villa Bianca, Rd; Grassia, G; Ialenti, A; Ianaro, A; Maffia, P; Sorrentino, R, 2004) |
"Terbutaline or dobutamine was administered to the rat at 30 min after LPS injection." | 5.31 | Comparison of terbutaline and dobutamine in rats with endotoxemia. ( Chen, SJ; Liaw, WJ; Tzao, C; Wang, JH; Wu, CC; Wu, JY, 2002) |
"Septic shock is characterized by a decrease in systemic vascular resistance." | 5.31 | Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia. ( Chen, A; Chen, SJ; Chou, TC; Liao, MH; Wu, CC; Yen, MH, 2000) |
" Previously, we reported an increase in protein tyrosine nitration (a marker of oxidative/nitrosative damage) and a decrease in the antioxidant enzyme extracellular superoxide dismutase (EC-SOD) in the lungs of young mice during endotoxemia-induced SIRS." | 3.77 | The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation. ( Evers, BM; Saito, H; Starr, ME; Ueda, J; Yamamoto, S, 2011) |
"To investigate the systemic, pulmonary, and hepatosplanchnic hemodynamic and metabolic effects of delayed treatment with ethyl pyruvate in a long-term porcine model of hyperdynamic endotoxemia." | 3.73 | Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia. ( Albicini, M; Asfar, P; Bracht, H; Brückner, UB; Ehrmann, U; Fink, MP; Hauser, B; Kick, J; Radermacher, P; Vogt, J; Wachter, U, 2005) |
"Effect of ornithine which is known to inhibit L-arginine uptake via cationic amino acid transport system has been tested, and compared to aminoguanidine, an iNOS inhibitor in lypopolysaccharide (LPS)-induced endotoxemia in rats." | 3.72 | Effect of ornithine on the ileal histology, nitric oxide production and lipid peroxidation in LPS-induced endotoxemia. ( Aydin, S; Büyükafşar, K; Caglikülekçi, M; Cinel, I; Cinel, L; Dirlik, M; Oral, U; Tamer, L, 2003) |
"In this lipopolysaccharide (LPS)-induced endotoxemia model, the effects of 3-aminobenzamide (3-AB), a poly(ADP-ribose) synthetase (PARS) inhibitor, on ileal apoptosis were evaluated by light microscopy and M30 cell death staining." | 3.71 | The role of poly(ADP-ribose) synthetase inhibition in preventing endotoxemia-induced intestinal epithelial apoptosis. ( Atici, S; Buyukafsar, K; Cinel, I; Cinel, L; Oral, U; Polat, A; Tamer, L, 2002) |
"The effect of 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (cPTIO), a nitric oxide (NO) scavenger that yields nitrogen dioxide (NO(2)) in a rat endotoxemia model was investigated." | 3.71 | Effect of an imidazolineoxyl nitric oxide on prostaglandin synthesis in experimental shock: possible role of nitrogen dioxide in prostacyclin synthase inactivation. ( Camacho, M; Molins-Pujol, AM; Soler, M; Vila, L, 2001) |
"Although the kidney has very important functions in the excretion of waste products and in interorgan metabolism, this study suggests that the kidney has a limited role in glutamine, arginine, and NO metabolism during late endotoxemia in rats." | 3.70 | Renal amino acid metabolism during endotoxemia in the rat. ( Cobben, DC; Dejong, CH; Deutz, NE; Hallemeesch, MM; Soeters, PB, 2000) |
"We studied the effects of administrating the nitric oxide synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME), or the nitric oxide precursor, L-arginine, on hemodynamic variables and serum nitrate concentrations in an anesthetized ovine model of endotoxemia to assess the effects on regional visceral blood flow and to determine whether L-arginine availability limits nitric oxide production." | 3.69 | L-arginine augments nitric oxide production and mesenteric blood flow in ovine endotoxemia. ( Allman, KG; Kennedy, MM; Stoddart, AP; Young, JD, 1996) |
"The effect of endotoxemia on the levels of amino acids, nitrates, nitrites and guanidino compounds was investigated." | 3.69 | Effect of endotoxemia on plasma and tissue levels of nitric oxide metabolites and guanidino compounds. ( De Deyn, PP; Deshmukh, DR; Ghole, VS; Marescau, B, 1997) |
"Arginine deficiency may underlie the cellular immune depression after surgery in obstructive jaundice, which is associated with gut-derived endotoxemia." | 3.69 | Arginine deficiency in bile duct-ligated rats after surgery: the role of plasma arginase and gut endotoxin restriction. ( Houdijk, AP; Teerlink, T; van Lambalgen, AA; van Leeuwen, PA; Visser, JJ, 1997) |
"Endotoxemia was achieved by continuous intravenous infusion of Escherichia coli lipopolysaccharide." | 2.70 | Adenosine triphosphate-magnesium dichloride during hyperdynamic porcine endotoxemia: effects on hepatosplanchnic oxygen exchange and metabolism. ( Asfar, P; Brückner, UB; Froeba, G; Georgieff, M; Ichai, C; Ince, C; Leverve, XM; Nalos, M; Pittner, A; Ploner, F; Radermacher, P; Theisen, M, 2002) |
"Endotoxemia was induced by an infusion of lipopolysac-charide (LPS) after HDL or LDL administration." | 1.34 | High-density lipoprotein prevents organ damage in endotoxemia. ( Chao, YF; Chen, HI; Harn, HJ; Lee, RP; Lin, CC; Lin, NT, 2007) |
"LPS induced cytotoxic brain swelling and maintained anatomical integrity of the blood-brain barrier." | 1.34 | Endotoxemia produces coma and brain swelling in bile duct ligated rats. ( Brooks, HF; Davies, C; Davies, NA; Harry, D; Hodges, SJ; Jalan, R; Mani, AR; Moore, KP; Shawcross, DL; Stadlbauer, V; Williams, R; Wright, G; Zou, Z; Zwingmann, C, 2007) |
"Endotoxemia was associated with renal dysfunctions as indicated by decreases in renal blood flow, urinary potassium excretion, and renal nitrate clearance." | 1.33 | N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia. ( Chiao, CW; Lee, SS; Su, MJ; Wu, CC, 2006) |
"Endotoxemia was induced in male rats by the intravenous injection of Salmonella typhosa lipopolysaccharide (LPS; 2 mg/kg/i." | 1.32 | Cloricromene in endotoxemia: role of NF-kappaB. ( Di Meglio, P; Di Rosa, M; di Villa Bianca, Rd; Grassia, G; Ialenti, A; Ianaro, A; Maffia, P; Sorrentino, R, 2004) |
"Terbutaline or dobutamine was administered to the rat at 30 min after LPS injection." | 1.31 | Comparison of terbutaline and dobutamine in rats with endotoxemia. ( Chen, SJ; Liaw, WJ; Tzao, C; Wang, JH; Wu, CC; Wu, JY, 2002) |
"Septic shock is characterized by a decrease in systemic vascular resistance." | 1.31 | Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia. ( Chen, A; Chen, SJ; Chou, TC; Liao, MH; Wu, CC; Yen, MH, 2000) |
"Acute lung injury is an important feature of sepsis and increased iNOS expression and NO production contribute to the pathogenesis of this syndrome." | 1.31 | Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia. ( Joseph, M; McCormack, DG; Mehta, S; Razavi, HM; Scott, JA; Wang, LF; Weicker, S, 2001) |
"L-lysine (500 mg kg-1) were compared with those of a known inhibitor of nitric oxide synthase, NG-nitro-L-arginine-methyl ester, L-NAME (25 mg kg-1) and with control animals (n = 6 per group)." | 1.30 | Effect of L-lysine on nitric oxide production in ovine endotoxaemia. ( Allman, KG; Stoddart, AP; Young, JD, 1998) |
"Midazolam sleep time was prolonged by lipopolysaccharide." | 1.30 | Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia. ( Funae, Y; Hirohashi, K; Imaoka, S; Inoue, M; Kinoshita, H; Minamiyama, Y; Takemura, S, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 28 (36.36) | 18.2507 |
2000's | 41 (53.25) | 29.6817 |
2010's | 8 (10.39) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Soriano, RN | 1 |
Ravanelli, MI | 1 |
Batalhao, ME | 2 |
Carnio, EC | 3 |
Branco, LG | 1 |
Chiu, CH | 1 |
Chyau, CC | 1 |
Chen, CC | 1 |
Lin, CH | 1 |
Cheng, CH | 1 |
Mong, MC | 1 |
Shen, HH | 1 |
Lam, KK | 1 |
Cheng, PY | 2 |
Kung, CW | 1 |
Chen, SY | 1 |
Lin, PC | 1 |
Chung, MT | 1 |
Lee, YM | 2 |
Tsai, WH | 1 |
Chiu, MC | 1 |
Jiau, SS | 1 |
Wu, ES | 1 |
Yen, MH | 5 |
Feng, SY | 1 |
Samarasinghe, T | 1 |
Phillips, DJ | 1 |
Alexiou, T | 1 |
Hollis, JH | 1 |
Yu, VY | 1 |
Walker, AM | 1 |
Starr, ME | 1 |
Ueda, J | 1 |
Yamamoto, S | 1 |
Evers, BM | 1 |
Saito, H | 1 |
Soriano, FG | 1 |
Lorigados, CB | 1 |
Pacher, P | 1 |
Szabó, C | 2 |
Jakob, SM | 1 |
Bracht, H | 2 |
Porta, F | 1 |
Balsiger, BM | 1 |
Brander, L | 1 |
Knuesel, R | 1 |
Feng, HQ | 1 |
Kolarova, A | 1 |
Ma, Y | 1 |
Takala, J | 1 |
Malardo, T | 1 |
Panunto-Castelo, A | 1 |
Almeida, LP | 1 |
Padilha, E | 1 |
Fontoura, IC | 1 |
Silva, CL | 1 |
Coelho-Castelo, AA | 1 |
Asfar, P | 2 |
Nalos, M | 1 |
Pittner, A | 1 |
Theisen, M | 1 |
Ichai, C | 1 |
Ploner, F | 1 |
Georgieff, M | 1 |
Ince, C | 1 |
Brückner, UB | 2 |
Leverve, XM | 1 |
Radermacher, P | 2 |
Froeba, G | 1 |
Khadour, FH | 1 |
Panas, D | 1 |
Ferdinandy, P | 1 |
Schulze, C | 1 |
Csont, T | 1 |
Lalu, MM | 2 |
Wildhirt, SM | 1 |
Schulz, R | 2 |
Cinel, I | 2 |
Buyukafsar, K | 2 |
Cinel, L | 2 |
Polat, A | 1 |
Atici, S | 1 |
Tamer, L | 2 |
Oral, U | 2 |
Levy, B | 1 |
Mansart, A | 1 |
Bollaert, PE | 1 |
Franck, P | 1 |
Mallie, JP | 1 |
Scharte, M | 1 |
Nofer, JR | 2 |
Aken, HV | 1 |
Waurick, R | 1 |
Meyer, J | 1 |
Bone, HG | 2 |
Bachetti, T | 1 |
Pasini, E | 1 |
Suzuki, H | 1 |
Ferrari, R | 1 |
Wu, JY | 1 |
Liaw, WJ | 1 |
Tzao, C | 1 |
Chen, SJ | 3 |
Wang, JH | 2 |
Wu, CC | 9 |
Heller, AR | 1 |
Heller, SC | 1 |
Borkenstein, A | 1 |
Stehr, SN | 1 |
Koch, T | 1 |
Dirlik, M | 1 |
Caglikülekçi, M | 1 |
Aydin, S | 1 |
Ogasawara, H | 1 |
Koizumi, T | 1 |
Yamamoto, H | 1 |
Kubo, K | 1 |
Tsao, CM | 1 |
Ho, ST | 1 |
Chen, A | 2 |
Wang, JJ | 1 |
Li, CY | 1 |
Tsai, SK | 1 |
Ianaro, A | 1 |
Maffia, P | 1 |
Grassia, G | 1 |
Di Meglio, P | 1 |
Sorrentino, R | 1 |
di Villa Bianca, Rd | 1 |
Di Rosa, M | 1 |
Ialenti, A | 1 |
Davies, NA | 2 |
Brealey, DA | 1 |
Stidwill, R | 1 |
Singer, M | 1 |
Svistunenko, DA | 1 |
Cooper, CE | 1 |
Chiao, CW | 3 |
Lee, SS | 2 |
Su, MJ | 2 |
Chen, KH | 1 |
Dong, HP | 1 |
Chen, HW | 1 |
Hsu, C | 1 |
Chiu, HY | 1 |
Lin, LC | 1 |
Yang, RC | 1 |
Hauser, B | 1 |
Kick, J | 1 |
Ehrmann, U | 1 |
Albicini, M | 1 |
Vogt, J | 1 |
Wachter, U | 1 |
Fink, MP | 1 |
Saia, RS | 1 |
Cena, J | 1 |
Chowdhury, R | 1 |
Lam, A | 1 |
Unno, N | 1 |
Uchiyama, T | 1 |
Yamamoto, N | 1 |
Inuzuka, K | 1 |
Sagara, D | 1 |
Konno, H | 1 |
Marshall, M | 1 |
Keeble, J | 1 |
Moore, PK | 1 |
Payabvash, S | 1 |
Ghahremani, MH | 1 |
Goliaei, A | 1 |
Mandegary, A | 1 |
Shafaroodi, H | 1 |
Amanlou, M | 1 |
Dehpour, AR | 1 |
Su, CF | 1 |
Yang, FL | 1 |
Chen, HI | 2 |
Lee, RP | 1 |
Lin, NT | 1 |
Chao, YF | 1 |
Lin, CC | 1 |
Harn, HJ | 1 |
Wright, G | 1 |
Shawcross, DL | 1 |
Hodges, SJ | 1 |
Zwingmann, C | 1 |
Brooks, HF | 1 |
Mani, AR | 1 |
Harry, D | 2 |
Stadlbauer, V | 1 |
Zou, Z | 2 |
Williams, R | 1 |
Davies, C | 1 |
Moore, KP | 1 |
Jalan, R | 1 |
El-Mas, MM | 1 |
Fan, M | 1 |
Abdel-Rahman, AA | 1 |
Granado, M | 1 |
Martín, AI | 1 |
López-Menduiña, M | 1 |
López-Calderón, A | 1 |
Villanúa, MA | 1 |
Lauer, S | 1 |
Daudel, F | 1 |
Traber, DL | 1 |
Ertmer, C | 1 |
Morelli, A | 1 |
Van Aken, H | 1 |
Lange, M | 1 |
Rehberg, S | 1 |
Ellger, B | 1 |
Stubbe, HD | 1 |
Kruse, C | 1 |
Westphal, M | 1 |
Bopp, C | 1 |
Hofer, S | 1 |
Busch, C | 1 |
Spöhr, F | 1 |
Weigand, MA | 1 |
Martin, E | 1 |
Klein, A | 1 |
Allman, KG | 2 |
Stoddart, AP | 2 |
Kennedy, MM | 1 |
Young, JD | 2 |
Campillo, B | 1 |
Bories, PN | 1 |
Benvenuti, C | 1 |
Dupeyron, C | 1 |
Milano, S | 2 |
Arcoleo, F | 2 |
D'Agostino, P | 2 |
Cillari, E | 2 |
Hock, CE | 2 |
Yin, K | 2 |
Yue, G | 1 |
Wong, PY | 2 |
Deshmukh, DR | 1 |
Ghole, VS | 1 |
Marescau, B | 1 |
De Deyn, PP | 1 |
Vos, TA | 1 |
Gouw, AS | 1 |
Klok, PA | 1 |
Havinga, R | 1 |
van Goor, H | 1 |
Huitema, S | 1 |
Roelofsen, H | 1 |
Kuipers, F | 1 |
Jansen, PL | 1 |
Moshage, H | 1 |
Houdijk, AP | 2 |
Teerlink, T | 2 |
Visser, JJ | 1 |
van Lambalgen, AA | 2 |
van Leeuwen, PA | 2 |
Kim, ND | 1 |
Kang, KW | 1 |
Kim, SG | 1 |
Schini-Kerth, VB | 1 |
Ou, J | 1 |
Carlos, TM | 1 |
Watkins, SC | 1 |
Saavedra, JE | 1 |
Keefer, LK | 1 |
Kim, YM | 1 |
Harbrecht, BG | 1 |
Billiar, TR | 1 |
Brovkovych, V | 2 |
Patton, S | 1 |
Brovkovych, S | 2 |
Kiechle, F | 2 |
Huk, I | 1 |
Maliński, T | 2 |
La Rosa, M | 1 |
Barbera, C | 1 |
Di Bella, G | 1 |
Vodovotz, Y | 1 |
Kopp, JB | 1 |
Takeguchi, H | 1 |
Shrivastav, S | 1 |
Coffin, D | 1 |
Lucia, MS | 1 |
Mitchell, JB | 1 |
Webber, R | 1 |
Letterio, J | 1 |
Wink, D | 1 |
Roberts, AB | 1 |
Liao, MH | 2 |
Demiryürek, AT | 1 |
Cakici, I | 1 |
Kanzik, I | 1 |
Tahamont, M | 1 |
Leach, M | 1 |
Hamilton, LC | 1 |
Olbrich, A | 1 |
Wray, GM | 2 |
Thiemermann, C | 2 |
Hinds, CJ | 1 |
Wang, Y | 1 |
Lawson, JA | 1 |
Jaeschke, H | 1 |
Németh, ZH | 2 |
Haskó, G | 2 |
Vizi, ES | 2 |
Salzman, AL | 1 |
Mehta, S | 2 |
Javeshghani, D | 1 |
Datta, P | 1 |
Levy, RD | 1 |
Magder, S | 1 |
Prins, HA | 1 |
Wiezer, MJ | 1 |
Thijs, LG | 1 |
Takemura, S | 1 |
Minamiyama, Y | 1 |
Imaoka, S | 1 |
Funae, Y | 1 |
Hirohashi, K | 1 |
Inoue, M | 1 |
Kinoshita, H | 1 |
Boczkowski, J | 1 |
Lisdero, CL | 1 |
Lanone, S | 1 |
Samb, A | 1 |
Carreras, MC | 1 |
Boveris, A | 1 |
Aubier, M | 1 |
Poderoso, JJ | 1 |
Anand, R | 1 |
Holt, S | 1 |
Davies, S | 1 |
Marley, R | 1 |
Fernando, B | 1 |
Goodier, D | 1 |
Moore, K | 1 |
Hallemeesch, MM | 2 |
Cobben, DC | 1 |
Dejong, CH | 1 |
Soeters, PB | 2 |
Deutz, NE | 2 |
Chou, TC | 1 |
Soler, M | 1 |
Camacho, M | 1 |
Molins-Pujol, AM | 1 |
Vila, L | 1 |
Wang, LF | 1 |
Weicker, S | 1 |
Scott, JA | 1 |
Joseph, M | 1 |
Razavi, HM | 1 |
McCormack, DG | 1 |
Iwase, M | 1 |
Yokota, M | 1 |
Kitaichi, K | 1 |
Wang, L | 1 |
Takagi, K | 1 |
Nagasaka, T | 1 |
Izawa, H | 1 |
Hasegawa, T | 1 |
Dobrucki, LW | 1 |
Dobrucki, I | 1 |
Kalinowski, L | 1 |
Metcalf, K | 1 |
Jungersten, L | 1 |
Lisander, B | 1 |
Yang, F | 1 |
Comtois, AS | 1 |
Fang, L | 1 |
Hartman, NG | 1 |
Blaise, G | 1 |
Vona-Davis, L | 1 |
Wearden, P | 1 |
Hill, J | 1 |
Hill, R | 1 |
1 review available for nitrates and Endotoxemia
Article | Year |
---|---|
Peroxynitrite: a putative cytotoxin.
Topics: Animals; Arteriosclerosis; Endotoxemia; Humans; Nitrates; Nitric Oxide; Oxidants; Reperfusion Injury | 1998 |
1 trial available for nitrates and Endotoxemia
Article | Year |
---|---|
Adenosine triphosphate-magnesium dichloride during hyperdynamic porcine endotoxemia: effects on hepatosplanchnic oxygen exchange and metabolism.
Topics: Adenosine Triphosphate; Animals; Endotoxemia; Hemodynamics; Interleukin-10; Liver; Liver Circulation | 2002 |
75 other studies available for nitrates and Endotoxemia
Article | Year |
---|---|
Glucocorticoids downregulate systemic nitric oxide synthesis and counteract overexpression of hepatic heme oxygenase-1 during endotoxin tolerance.
Topics: Adrenalectomy; Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Down-Regulation; Endo | 2013 |
Polysaccharide extract of Cordyceps sobolifera attenuates renal injury in endotoxemic rats.
Topics: Animals; Antioxidants; Cordyceps; Endotoxemia; Enzymes; Interleukin-6; Kidney; Lipopolysaccharides; | 2014 |
Alpha-lipoic acid prevents endotoxic shock and multiple organ dysfunction syndrome induced by endotoxemia in rats.
Topics: Animals; Antioxidants; Antithrombins; Aorta; Caspase 3; Disulfides; Endotoxemia; Enzyme Activation; | 2015 |
Anti-inflammatory effects of LK-3, on LPS-induced sepsis in rats.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Dextromethorphan; Endotoxemia; Heart Rate; Lipopo | 2008 |
Acute and chronic effects of endotoxin on cerebral circulation in lambs.
Topics: Acute Disease; Animals; Animals, Newborn; Body Temperature; Bradykinin; Brain; Cerebrovascular Circu | 2010 |
The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation.
Topics: Aging; Animals; Blotting, Western; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Endotoxem | 2011 |
Effects of a potent peroxynitrite decomposition catalyst in murine models of endotoxemia and sepsis.
Topics: Animals; Endotoxemia; Lipopolysaccharides; Malondialdehyde; Metalloporphyrins; Mice; Nitrates; Nitri | 2011 |
Effects of cardiac preload reduction and dobutamine on hepatosplanchnic blood flow regulation in porcine endotoxemia.
Topics: Acidosis; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Carotid Arter | 2012 |
Low-dose plasmid DNA treatment increases plasma vasopressin and regulates blood pressure in experimental endotoxemia.
Topics: Animals; Blood Pressure; Body Temperature; Cell Line; DNA; Endotoxemia; Heart Rate; Interleukin-6; L | 2012 |
Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats.
Topics: Animals; Endotoxemia; Heart Diseases; Hydrogen Peroxide; Lipopolysaccharides; Male; Myocardial Contr | 2002 |
The role of poly(ADP-ribose) synthetase inhibition in preventing endotoxemia-induced intestinal epithelial apoptosis.
Topics: Animals; Apoptosis; Benzamides; Endotoxemia; Epithelium; Escherichia coli Infections; Immunohistoche | 2002 |
Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats.
Topics: Acidosis, Lactic; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Gas Analysis; Diseas | 2003 |
Nicotinamide increases systemic vascular resistance in ovine endotoxemia.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Disease Mode | 2003 |
Species-specific modulation of the nitric oxide pathway after acute experimentally induced endotoxemia.
Topics: Amidines; Animals; Benzylamines; Blood Pressure; Breath Tests; Disease Models, Animal; Drug Evaluati | 2003 |
Comparison of terbutaline and dobutamine in rats with endotoxemia.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Blood Pressure; Dobutamine; Endotoxemia; Heart Rate; Lipop | 2002 |
Modulation of host defense by hydrocortisone in stress doses during endotoxemia.
Topics: Animals; Biomarkers; Blood Pressure; Colony Count, Microbial; Dose-Response Relationship, Drug; Endo | 2003 |
Effect of ornithine on the ileal histology, nitric oxide production and lipid peroxidation in LPS-induced endotoxemia.
Topics: Animals; Dose-Response Relationship, Drug; Endotoxemia; Enzyme Inhibitors; Female; Guanidines; Ileum | 2003 |
Effects of a selective nitric oxide synthase inhibitor on endotoxin-induced alteration in hypoxic pulmonary vasoconstriction in sheep.
Topics: Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Hemodynamics | 2003 |
Low-dose dexamethasone ameliorates circulatory failure and renal dysfunction in conscious rats with endotoxemia.
Topics: Animals; Arteries; Blood Pressure; Blotting, Western; Calcium; Dexamethasone; Endotoxemia; Escherich | 2004 |
Cloricromene in endotoxemia: role of NF-kappaB.
Topics: Animals; Aorta, Thoracic; Chromonar; Electrophoretic Mobility Shift Assay; Endotoxemia; In Vitro Tec | 2004 |
Nitrosyl heme production compared in endotoxemic and hemorrhagic shock.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Electr | 2005 |
Thaliporphine increases survival rate and attenuates multiple organ injury in LPS-induced endotoxaemia.
Topics: Animals; Aorta; Aporphines; Blood Glucose; Endotoxemia; Hemodynamics; In Vitro Techniques; Interleuk | 2005 |
Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.
Topics: Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug; | 2005 |
Previous heat shock treatment attenuates lipopolysaccharide-induced hyporesponsiveness of platelets in rats.
Topics: Animals; Blood Platelets; Catalase; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Hot T | 2005 |
Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia.
Topics: Acidosis; Animals; Blood Pressure; Disease Models, Animal; Diuresis; Endotoxemia; Hemodynamics; Lipi | 2005 |
N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia.
Topics: Acute Kidney Injury; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; | 2006 |
Thermoregulatory role of inducible nitric oxide synthase in lipopolysaccharide-induced hypothermia.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Body Temperature Regulatio | 2006 |
Matrix metalloproteinases contribute to endotoxin and interleukin-1beta induced vascular dysfunction.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Collagenases; Endotoxemia; Endotoxins; Gelatinases; In | 2006 |
Portal triad occlusion induces endotoxin tolerance: role of portal congestion.
Topics: Animals; Constriction; Cytokines; Endotoxemia; Endotoxins; Hemostasis, Surgical; Interleukin-6; Isch | 2006 |
Effect of a nitric oxide releasing derivative of paracetamol in a rat model of endotoxaemia.
Topics: Acetaminophen; Acetylcholine; Animals; Aspartate Aminotransferases; Blood Pressure; Creatinine; Cycl | 2006 |
Nitric oxide modulates glutathione synthesis during endotoxemia.
Topics: Animals; Body Weight; Catalase; Cysteine; Disease Models, Animal; Eating; Endotoxemia; Glutamate-Cys | 2006 |
Inhibition of inducible nitric oxide synthase attenuates acute endotoxin-induced lung injury in rats.
Topics: Animals; Endotoxemia; Endotoxins; Enzyme Inhibitors; Infusions, Intravenous; Interleukin-1beta; Isot | 2007 |
High-density lipoprotein prevents organ damage in endotoxemia.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Blood Pressure; Bl | 2007 |
Endotoxemia produces coma and brain swelling in bile duct ligated rats.
Topics: Ammonia; Animals; Brain; Brain Edema; Capillaries; Cholestasis, Extrahepatic; Coma; Consciousness; C | 2007 |
Endotoxemia-mediated induction of cardiac inducible nitric-oxide synthase expression accounts for the hypotensive effect of ethanol in female rats.
Topics: Amidines; Ampicillin; Animals; Anti-Bacterial Agents; Benzylamines; Blood Pressure; Cardiac Output; | 2008 |
GH-releasing peptide-2 administration prevents liver inflammatory response in endotoxemia.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Cells, Culture | 2008 |
Somatostatin infusion increases intestinal ischemia and does not improve vasoconstrictor response to norepinephrine in ovine endotoxemia.
Topics: Animals; Endotoxemia; Female; Hemodynamics; Hypotension; Ischemia; Nitrates; Nitrites; Norepinephrin | 2008 |
Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cyclic GMP; Dose-Respon | 2008 |
L-arginine augments nitric oxide production and mesenteric blood flow in ovine endotoxemia.
Topics: Animals; Arginine; Blood; Cardiovascular System; Diuresis; Endotoxemia; Enzyme Inhibitors; NG-Nitroa | 1996 |
Serum and urinary nitrate levels in liver cirrhosis: endotoxemia, renal function and hyperdynamic circulation.
Topics: Analysis of Variance; Cardiac Output, High; Case-Control Studies; Echocardiography, Doppler; Endotox | 1996 |
Intraperitoneal injection of tetracyclines protects mice from lethal endotoxemia downregulating inducible nitric oxide synthase in various organs and cytokine and nitrate secretion in blood.
Topics: Animals; Anti-Bacterial Agents; Cytokines; Down-Regulation; Doxycycline; Endotoxemia; Enzyme Inducti | 1997 |
Effects of inhibition of nitric oxide synthase by aminoguanidine in acute endotoxemia.
Topics: Acute Disease; Animals; Endotoxemia; Enzyme Inhibitors; Guanidines; Hemodynamics; Lipopolysaccharide | 1997 |
Effect of endotoxemia on plasma and tissue levels of nitric oxide metabolites and guanidino compounds.
Topics: Amino Acids; Animals; Endotoxemia; Guanidines; Kidney; Lipopolysaccharides; Liver; Lung; Male; Nitra | 1997 |
Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats.
Topics: Amino Acid Sequence; Animals; Antibodies; Bile; Bile Canaliculi; Bile Ducts; Endotoxemia; Endotoxins | 1997 |
Arginine deficiency in bile duct-ligated rats after surgery: the role of plasma arginase and gut endotoxin restriction.
Topics: Animals; Arginase; Arginine; Cholestasis; Cholestyramine Resin; Common Bile Duct; Endotoxemia; Hemat | 1997 |
Inhibition of inducible nitric oxide synthase expression and stimulation of the endothelial formation of nitric oxide most likely accounts for the protective effect of 2-(allylthio)pyrazine in a murine model of endotoxemia.
Topics: Animals; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Enzyme Inhibitors; | 1997 |
Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia.
Topics: Animals; Apoptosis; DNA Fragmentation; Endotoxemia; Intercellular Adhesion Molecule-1; Liver; Male; | 1997 |
In situ measurement of nitric oxide, superoxide and peroxynitrite during endotoxemia.
Topics: Animals; Aorta; Endothelium, Vascular; Endotoxemia; Escherichia coli; Lipopolysaccharides; Nitrates; | 1997 |
Doxycycline reduces mortality to lethal endotoxemia by reducing nitric oxide synthesis via an interleukin-10-independent mechanism.
Topics: Animals; Anti-Bacterial Agents; Doxycycline; Endotoxemia; Female; Interleukin-10; Lipopolysaccharide | 1998 |
Increased mortality, blunted production of nitric oxide, and increased production of TNF-alpha in endotoxemic TGF-beta1 transgenic mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Adhesion; Edema; Endotoxemia; Gene | 1998 |
Combined effects of dexamethasone and aminoguanidine on rats with endotoxemia.
Topics: Animals; Blood Pressure; Dexamethasone; Drug Interactions; Endotoxemia; Enzyme Inhibitors; Guanidine | 1998 |
Beneficial effects of tetramethylpyrazine, an active constituent of Chinese herbs, on rats with endotoxemia.
Topics: Animals; Blood Pressure; Endotoxemia; Heart Rate; Hypotension; In Vitro Techniques; Male; Medicine, | 1998 |
Time-dependent cardiovascular and inflammatory changes in acute endotoxemia.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cardiovascular System; Endotoxemia; Free Radic | 1998 |
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc | 1998 |
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidne | 1998 |
Differential effect of 2-aminoethyl-isothiourea, an inhibitor of the inducible nitric oxide synthase, on microvascular blood flow and organ injury in models of hepatic ischemia-reperfusion and endotoxemia.
Topics: Alanine Transaminase; Animals; beta-Aminoethyl Isothiourea; Blood Circulation; Blood Pressure; Endot | 1998 |
Pyrrolidine dithiocarbamate augments IL-10, inhibits TNF-alpha, MIP-1alpha, IL-12, and nitric oxide production and protects from the lethal effect of endotoxin.
Topics: Animals; Antioxidants; Chemokine CCL3; Chemokine CCL4; Endotoxemia; Interferon-gamma; Interleukin-1; | 1998 |
Effect of L-lysine on nitric oxide production in ovine endotoxaemia.
Topics: Animals; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Lysine; NG-Nitroarginine Methyl Ester; Nitrat | 1998 |
An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice.
Topics: Adenosine; Animals; Corticosterone; Endotoxemia; Endotoxins; Interferon-gamma; Interleukin-1; Interl | 1998 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Mod | 1999 |
Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat.
Topics: Animals; Arginase; Arginine; Blood Chemical Analysis; Cattle; Citrulline; Digestive System; Endotoxe | 1999 |
Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endotoxemia; Hydroxylat | 1999 |
Endogenous peroxynitrite mediates mitochondrial dysfunction in rat diaphragm during endotoxemia.
Topics: Animals; Diaphragm; Endotoxemia; Escherichia coli; Hydrogen Peroxide; Kinetics; Lipopolysaccharides; | 1999 |
Increased sensitivity to endotoxemia in the bile duct-ligated cirrhotic Rat.
Topics: Animals; Bile Ducts; Cell Nucleus; Dinoprost; Disease Susceptibility; Endotoxemia; Kidney Function T | 1999 |
Comparison between effects of dantrolene and nifedipine on lipopolysaccharide-induced endotoxemia in the anesthetized rats.
Topics: Anesthesia; Animals; Blood Glucose; Blood Pressure; Body Temperature; Dantrolene; Endotoxemia; Lipop | 1999 |
Renal amino acid metabolism during endotoxemia in the rat.
Topics: Amino Acids; Animals; Carbon Dioxide; Citrulline; Endotoxemia; Endotoxins; Escherichia coli; Glutami | 2000 |
Terbutaline prevents circulatory failure and mitigates mortality in rodents with endotoxemia.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Drug Interactions | 2000 |
Effect of an imidazolineoxyl nitric oxide on prostaglandin synthesis in experimental shock: possible role of nitrogen dioxide in prostacyclin synthase inactivation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Benzoates; Culture Techniques; Cytochrome P-450 Enzyme | 2001 |
Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Chimera; Endotoxemia; In Vitro Techniques; | 2001 |
Cardiac functional and structural alterations induced by endotoxin in rats: importance of platelet-activating factor.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Echocardiography; Electrocardiography | 2001 |
Nitric oxide measurements during endotoxemia.
Topics: Animals; Endotoxemia; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred WKY; Superoxides | 2001 |
Renal arginine and protein synthesis are increased during early endotoxemia in mice.
Topics: Amino Acids; Ammonia; Animals; Arginine; Citrulline; Endotoxemia; Female; Kidney; Lipopolysaccharide | 2002 |
Effective inhibition of nitric oxide production by aminoguanidine does not reverse hypotension in endotoxaemic rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Endotoxemia; Guanidines; Hypotension; Mal | 2002 |
Nitric oxide-derived nitrate anion contributes to endotoxic shock and multiple organ injury/dysfunction.
Topics: Analysis of Variance; Animals; Cell Membrane Permeability; Endotoxemia; Hemodynamics; Lipopolysaccha | 2002 |
Cardiac response to nitric oxide synthase inhibition using aminoguanidine in a rat model of endotoxemia.
Topics: Animals; Disease Models, Animal; Endotoxemia; Endotoxins; Enzyme Inhibitors; Guanidines; Heart; In V | 2002 |