nitrates has been researched along with Down Syndrome in 7 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to evaluate the role of plasma endothelin-1 (ET-1) and nitrate levels in DS children with complete AVSD-associated pulmonary hypertension (PH) and compare this to ND patients." | 7.75 | Plasma endothelin-1 and nitrate levels in Down's syndrome with complete atrioventricular septal defect-associated pulmonary hypertension: a comparison with non-Down's syndrome children. ( Karademir, S; Karakurt, C; Ocal, B; Oğuz, D; Senocak, F; Sungur, M, 2009) |
| " Thus, we aimed to assess a set of urinary oxidative/nitrosative stress biomarkers in children with DS, with and without hypothyroidism, which comprise: 8-hydroxy-2'-deoxyguanosine (8-OHdG), isoprostane 15-F(2t)-IsoP, thiobarbituric acid-reacting substances (TBARS), advanced glycation end products (AGEs), dityrosine (diTyr), hydrogen peroxide (H(2)O(2)) and nitrite/nitrate (NOx)." | 3.77 | Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome. ( Campos, C; Casado, A; Guzmán, R; López-Fernández, E, 2011) |
| " We aimed to evaluate the role of plasma endothelin-1 (ET-1) and nitrate levels in DS children with complete AVSD-associated pulmonary hypertension (PH) and compare this to ND patients." | 3.75 | Plasma endothelin-1 and nitrate levels in Down's syndrome with complete atrioventricular septal defect-associated pulmonary hypertension: a comparison with non-Down's syndrome children. ( Karademir, S; Karakurt, C; Ocal, B; Oğuz, D; Senocak, F; Sungur, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ripoll, C | 1 |
| Dairou, J | 1 |
| Stora, S | 1 |
| Delabar, JM | 1 |
| Janel, N | 1 |
| Sungur, M | 1 |
| Ocal, B | 1 |
| Oğuz, D | 1 |
| Karademir, S | 1 |
| Karakurt, C | 1 |
| Senocak, F | 1 |
| Cua, CL | 1 |
| Rogers, LK | 1 |
| Chicoine, LG | 1 |
| Augustine, M | 1 |
| Jin, Y | 1 |
| Nash, PL | 1 |
| Nelin, LD | 1 |
| Campos, C | 1 |
| Guzmán, R | 1 |
| López-Fernández, E | 1 |
| Casado, A | 1 |
| Horiguchi, T | 1 |
| Uryu, K | 1 |
| Giasson, BI | 1 |
| Ischiropoulos, H | 1 |
| LightFoot, R | 1 |
| Bellmann, C | 1 |
| Richter-Landsberg, C | 1 |
| Lee, VM | 1 |
| Trojanowski, JQ | 1 |
| Colas, D | 1 |
| London, J | 1 |
| Gharib, A | 1 |
| Cespuglio, R | 1 |
| Sarda, N | 1 |
| Mirochnitchenko, O | 1 |
| Inouye, M | 1 |
7 other studies available for nitrates and Down Syndrome
| Article | Year |
|---|---|
Plasma nitrate levels are increased in adult Down syndrome patients.
Topics: Adult; Biomarkers; Down Syndrome; Humans; Nitrates | 2013 |
Plasma endothelin-1 and nitrate levels in Down's syndrome with complete atrioventricular septal defect-associated pulmonary hypertension: a comparison with non-Down's syndrome children.
Topics: Child; Child, Preschool; Down Syndrome; Endothelin-1; Female; Heart Septal Defects, Atrial; Heart Se | 2009 |
Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.
Topics: Arginine; Biomarkers; Down Syndrome; Female; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates | 2011 |
Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Biomarkers; Child; Child, Preschool; Deoxyguanosine; Dinopr | 2011 |
Nitration of tau protein is linked to neurodegeneration in tauopathies.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Corte | 2003 |
Sleep-wake architecture in mouse models for Down syndrome.
Topics: Animals; Brain Stem; Cerebral Cortex; Disease Models, Animal; Down Syndrome; Mice; Mice, Transgenic; | 2004 |
Effect of overexpression of human Cu,Zn superoxide dismutase in transgenic mice on macrophage functions.
Topics: Animals; Base Sequence; Blood Bactericidal Activity; Cell Nucleus; DNA Primers; Down Syndrome; Human | 1996 |