Page last updated: 2024-10-19

nitrates and Disease Models, Animal

nitrates has been researched along with Disease Models, Animal in 476 studies

Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" This study evaluates the effects of agmatine on ovalbumin (OVA)-induced allergic inflammation of the airways."8.12Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. ( Abdelaziz, RR; Elmahdi, HS; Suddek, GM; Еlmahdy, MK, 2022)
" In this study, we hypothesized that treatment with inorganic nitrate could prevent the increase in sympathetic nerve activity in an experimental model of Ang II (angiotensin II)-induced hypertension."7.91Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II-Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity. ( Balarini, CM; Braga, VA; Carlström, M; Carvalho-Galvão, A; Cruz, JC; Guimarães, DD; Lundberg, JO; Marques, SM; Naves, LM; Pedrino, GR; Persson, AEG; Weitzberg, E; Zhuge, Z, 2019)
"The present study was designed to investigate the effect of ascorbic acid (AA) treatment on the anxiety related behavioral and neurochemical alterations."7.91Nitrergic signaling modulation by ascorbic acid treatment is responsible for anxiolysis in mouse model of anxiety. ( Garg, C; Garg, M; Walia, V, 2019)
"Curcumin has been reported to have anti-inflammatory, antioxidant and hypoglycaemic properties, besides reducing mortality in sepsis."7.85Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis. ( Catalão, CH; de Freitas, LA; Felippotti, TT; Oliveira-Pelegrin, GR; Petenusci, S; Rocha, MJ; Silva, LS, 2017)
"Compared with controls, sodium nitrite administered either pre-occlusion or pre-reperfusion markedly suppressed the number and severity of ventricular arrhythmias during occlusion and increased survival (0% vs."7.81Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? ( Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á, 2015)
"To investigate the effect of morphine on the reduced uteroplacental perfusion pressure (RUPP) model of pre-eclampsia in rats."7.79Effect of morphine on the reduced uteroplacental perfusion model of pre-eclampsia in rats. ( Dehpour, AR; Ejtemaei Mehr, S; Gharedaghi, MH; Javadi-Paydar, M; Javadian, P; Salmanian, B; Shamshirsaz, AA, 2013)
"Effects of nitrates NaNO(3), KNO(3), Mg(NO(3)) 2 on animals (Wistar rats) were studied on the basis of the experimental model of ischemic stroke induced by the occlusion of two carotid arteries."7.78[The effect of nitrates on the outcome of acute experimental ischemic stroke]. ( Krushinskiĭ, AL; Kuzenkov, VS; Reutov, VP, 2012)
"We designed the present study to evaluate the efficacy of melatonin (M) on the severity of necrotizing enterocolitis (NEC) in a neonatal rat model."7.77Melatonin ameliorates necrotizing enterocolitis in a neonatal rat model. ( Gundogdu, G; Guven, A; Korkmaz, A; Oztas, E; Ozturk, H; Uysal, B, 2011)
" Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1."7.76Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010)
"Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by autonomic failure, parkinsonism, cerebellar ataxia, and oligodendrocytic accumulation of alpha-synuclein (alphasyn)."7.75Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. ( Adame, A; Inglis, C; Lee, PH; Mante, M; Masliah, E; Rockenstein, E; Stefanova, N; Ubhi, K; Wenning, GK, 2009)
"Population studies indicate that moderate hyperbilirubinemia is associated with reduced incidence of cardiovascular diseases, including hypertension."7.75Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice. ( Granger, JP; Stec, DE; Vera, T, 2009)
"Study hemodynamic pattern and lipoperoxidation during methylene blue (MB) treatment on taurocholate - enterokinase induced acute pancreatitis (AP)."7.74Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model. ( Baldo, CF; Ceneviva, R; Evora, PR; Meirelles, RF; Viaro, F, 2008)
" The present study is aimed to investigate the effect of L-arginine (as a natural NO donor) supplementation on NO metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial NO production."7.74L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia. ( Haghjooy Javanmard, S; Monajemi, A; Nematbakhsh, M, 2008)
"These results suggest that pretreatment with atorvastatin attenuates APE-induced pulmonary hypertension and increases 24-hr survival rate by mechanisms that result in attenuated increases in lung activated MMP-9 after APE."7.74Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9. ( Alves-Filho, JC; Cunha, FQ; Figueiredo-Lopes, L; Gerlach, RF; Semprini, MC; Souza-Costa, DC; Tanus-Santos, JE, 2007)
"To evaluate the effect of topically administered ascorbic acid on experimentally induced corneal neovascularization in the rat model."7.74Inhibition of corneal angiogenesis by ascorbic acid in the rat model. ( Conway, MD; DellaCroce, JT; Kivilcim, M; Morales, AM; Peyman, GA, 2007)
"Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)."7.74The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008)
"To investigate the systemic, pulmonary, and hepatosplanchnic hemodynamic and metabolic effects of delayed treatment with ethyl pyruvate in a long-term porcine model of hyperdynamic endotoxemia."7.73Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia. ( Albicini, M; Asfar, P; Bracht, H; Brückner, UB; Ehrmann, U; Fink, MP; Hauser, B; Kick, J; Radermacher, P; Vogt, J; Wachter, U, 2005)
"To evaluate the potential of S-nitroso-N-acetylcysteine (SNAC) in inhibition of lipid peroxidation and the effect of oral SNAC administration in the prevention of nonalcoholic fatty liver disease (NAFLD) in an animal model."7.73Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats. ( Abdalla, DS; Alves, VA; Carrilho, FJ; de Lima, VM; de Oliveira, CP; de Oliveira, MG; Laurindo, FR; Lopasso, FP; Simplicio, FI; Yuahasi, K, 2006)
"To assess the antioxidant effects of atorvastatin (atorva) on dexamethasone (dex)-induced hypertension, 60 male Sprague-Dawley rats were treated with atorva 30 mg/kg/day or tap water for 15 days."7.73Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat. ( Huang, TG; Mondo, CK; Su, JZ; Yang, WS, 2006)
"To clarify the role of nitric oxide (NO) in the pathogenesis of seizures in susceptible EL mice, we investigated effects of three drugs potentially related to NO production, MK-801, dantrolene, and FK506, on convulsive seizures and brain NO metabolites (NOx)."7.71Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice. ( Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M, 2001)
" Here we investigated whether in vivo N-acetylcysteine treatment inhibits cellular injury in macrophages collected from rats subjected to zymosan-induced shock."7.70Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1999)
" The current study was designed to investigate the protective effect of melatonin, a radical scavenger and antioxidant, on non-septic shock induced by zymosan in the rat."7.70Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. ( Caputi, AP; Cuzzocrea, S; El-Sokkary, GH; Hassanein, AF; Reiter, RJ; Tan, DX, 1999)
"Hyperhomocysteinemia (HH) is an independent risk factor for atherosclerosis, including peripheral arterial occlusive disease (PAOD)."7.70Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. ( Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S, 2000)
"To investigate the role of carbon monoxide (CO) in the pathogenesis of asthma."7.70[Evidence of increased endogenous carbon monoxide production in asthma]. ( Jiang, D; Li, H; Shi, Y, 1999)
"Levosimendan was administered after ROSC with a loading dose of 10 μg/kg and then infused at 0."5.56Synergistic Effects of Moderate Therapeutic Hypothermia and Levosimendan on Cardiac Function and Survival After Asphyxia-Induced Cardiac Arrest in Rats. ( Chang, WT; Chen, WJ; Huang, CH; Tsai, MS; Wang, CH, 2020)
"Ischemia was followed by a significant increase in muscle myeloperoxidase activity, as well as interleukin-6 and thiobarbituric acid reactive substances species levels."5.48N-acetylcysteine effects on a murine model of chronic critical limb ischemia. ( Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F, 2018)
"Dimethyl fumarate (DMF) is an important agent against inflammatory response and reactive species in CNS disorders."5.48Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis. ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018)
" Further studies evaluating longer-duration nitrite therapy and/or additional nitrite dosing strategies are warranted to more fully evaluate the therapeutic potential of nitrite therapy in peripheral vascular disease."5.42Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome. ( Bradley, JM; Brewster, LP; Calvert, JW; Chang, CC; Goodchild, TT; Islam, KN; Lefer, DJ; Pipinos, II; Polhemus, DJ; Tao, YX, 2015)
"Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes."5.39Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. ( Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA, 2013)
"Acute lung injury is still a significant clinical problem with a high mortality rate and there are few effective therapies in clinic."5.38Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB. ( Chen, L; Gao, M; Jiang, W; Kou, J; Li, J; Shao, F; Sun, Q; Wang, J; Yu, B, 2012)
"Cepharanthine (CE) is a plant alkaloid that possesses bioactive properties, with various known actions."5.37Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation. ( Hagiwara, S; Hasegawa, A; Koga, H; Kudo, K; Kusaka, J; Noguchi, T, 2011)
"Lung, liver, and bone cancer mortality rate ratios in the MPA worker cohort were compared to those seen in beagle dogs, and models of the excess relative risk of lung, liver, and bone cancer mortality from the MPA worker cohort were applied to data from life-span studies of beagle dogs."5.36Lung, liver and bone cancer mortality after plutonium exposure in beagle dogs and nuclear workers. ( Frey, GD; Hoel, DG; Lackland, D; Mohr, LC; Wilson, DA, 2010)
"Post-treatment with magnolol significantly attenuated the deleterious haemodynamic changes (e."5.36Beneficial effects of magnolol in a rodent model of endotoxin shock. ( Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH, 2010)
"Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue."5.36Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model. ( Chen, W; Cheng, JT; Cheng, KC; Shen, KH; Wu, HT; Yeh, CH, 2010)
"Hypercholesterolemia is a major risk factor for the development and progression of cardiovascular diseases including atherosclerosis."5.35Suppression of diet-induced hypercholesterolemia by scutellarin in rats. ( Chan, SW; Chen, SL; Cheng, HL; Guo, DJ; Li, Q; Wu, JH, 2009)
"Ozone treatment significantly reduced the severity of NEC by modulating antioxidative defense and antiinflammatory protection in our experimental animal model."5.35Medical ozone therapy reduces oxidative stress and intestinal damage in an experimental model of necrotizing enterocolitis in neonatal rats. ( Gundogdu, G; Guven, A; Korkmaz, A; Oztas, E; Ozturk, H; Uysal, B; Vurucu, S, 2009)
" During this study we investigated the alterations in NO synthesis and bioavailability in a model for dietary modulations of insulin sensitivity."5.34Nitric oxide bioavailability and not production is first altered during the onset of insulin resistance in sucrose-fed rats. ( Blouet, C; Huneau, JF; Mariotti, F; Mathe, V; Tome, D, 2007)
"Proteinuria was significantly lower in L-arginine-treated animals from week 24 onward (p<0."5.32Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure. ( Albrecht, EW; Smit-van Oosten, A; Stegeman, CA; van Goor, H, 2003)
"enalapril alone to enhance vascular effects, increase LV contractility and prevent unfavorable remodeling and are consistent with vascular delivery of exogenous NO."5.32A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. ( Condorelli, G; Del Soldato, P; Dieterle, T; Gu, Y; Iwanaga, Y; Ongini, E; Peterson, KL; Presotto, C; Ross, J, 2004)
" Uveitis, which is an inflammation of the highly vascular uveal tract in the eye, is a debilitating condition that can lead to visual impairment and blindness."4.80Nitric oxide and peroxynitrite production in ocular inflammation. ( Allen, JB; Keng, T; Privalle, C, 1998)
" This study evaluates the effects of agmatine on ovalbumin (OVA)-induced allergic inflammation of the airways."4.12Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study. ( Abdelaziz, RR; Elmahdi, HS; Suddek, GM; Еlmahdy, MK, 2022)
" In this study, we hypothesized that treatment with inorganic nitrate could prevent the increase in sympathetic nerve activity in an experimental model of Ang II (angiotensin II)-induced hypertension."3.91Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II-Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity. ( Balarini, CM; Braga, VA; Carlström, M; Carvalho-Galvão, A; Cruz, JC; Guimarães, DD; Lundberg, JO; Marques, SM; Naves, LM; Pedrino, GR; Persson, AEG; Weitzberg, E; Zhuge, Z, 2019)
"The present study was designed to investigate the effect of ascorbic acid (AA) treatment on the anxiety related behavioral and neurochemical alterations."3.91Nitrergic signaling modulation by ascorbic acid treatment is responsible for anxiolysis in mouse model of anxiety. ( Garg, C; Garg, M; Walia, V, 2019)
" Our aim was to examine local and remote consequences of ASA-Tris administration in 2-,4-,6-trinitrobenzene-sulfonic acid (TNBS)-induced colitis as compared to ASA or mesalamine (5-aminosalicylate) treatment."3.88Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. ( Boros, M; Érces, D; Ghyczy, M; Hartmann, P; Jász, DK; Lajkó, N; Molnár, R; Szűcs, S; Tóth, G; Ugocsai, M; Varga, G, 2018)
"The silver and potassium nitrate solution effectively induced corneal angiogenesis."3.85Corneal angiogenesis based on different protocols of alkaline cauterization in murine models. ( Aldrovani, M; Claros-Chacaltana, FDY; Kobashigawa, KK; Laus, JL; Padua, IRM; Valdetaro, GP, 2017)
"Curcumin has been reported to have anti-inflammatory, antioxidant and hypoglycaemic properties, besides reducing mortality in sepsis."3.85Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis. ( Catalão, CH; de Freitas, LA; Felippotti, TT; Oliveira-Pelegrin, GR; Petenusci, S; Rocha, MJ; Silva, LS, 2017)
" Substrates for endogenous nitric oxide (NO) production, including organic nitrates and dietary nitrate, may support NO production in age-related conditions, including osteoporosis."3.85Increasing dietary nitrate has no effect on cancellous bone loss or fecal microbiome in ovariectomized rats. ( Conley, MN; Hord, NG; Iwaniec, UT; Roberts, C; Sharpton, TJ, 2017)
" Treatment with ixmyelocel-T in a rat model of hind limb ischemia resulted in significantly increased blood flow perfusion and capillary density, gene expression and plasma levels of the anti-inflammatory cytokine interleukin (IL)-10, plasma nitrates, plasma platelet-derived growth factor (PDGF)-BB, vascular endothelial growth factor (VEGF) expression, and significantly decreased plasma thiobarbituric acid reactive substances (TBARS)."3.81Therapeutic potential of ixmyelocel-T, an expanded autologous multicellular therapy for treatment of ischemic cardiovascular diseases. ( Bartel, RL; Ledford, KJ; Murphy, N; Tubo, R; Zeigler, F, 2015)
"Compared with controls, sodium nitrite administered either pre-occlusion or pre-reperfusion markedly suppressed the number and severity of ventricular arrhythmias during occlusion and increased survival (0% vs."3.81Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved? ( Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á, 2015)
" The electrophilic lipid 10-nitro-oleic acid (NO2-OA) inhibited hydrolase activity and also lowered BP in an angiotensin II-induced hypertension model in wild-type (WT) but not KI mice."3.80Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. ( Charles, RL; Eaton, P; Freeman, BA; Hammock, BD; Kamynina, A; Morisseau, C; Prysyazhna, O; Rudyk, O; Yang, J, 2014)
"To investigate the effect of morphine on the reduced uteroplacental perfusion pressure (RUPP) model of pre-eclampsia in rats."3.79Effect of morphine on the reduced uteroplacental perfusion model of pre-eclampsia in rats. ( Dehpour, AR; Ejtemaei Mehr, S; Gharedaghi, MH; Javadi-Paydar, M; Javadian, P; Salmanian, B; Shamshirsaz, AA, 2013)
"The present study was aimed to evaluate the antihypertensive effect of diosmin in deoxycorticosterone acetate (DOCA)-salt induced hypertension in male Wistar rats."3.78Diosmin, a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats. ( Raja, B; Silambarasan, T, 2012)
" Ozone therapy (OT) is shown to reduce inflammation and necrosis in several entities."3.78The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury. ( Akgul, EO; Cakir, E; Cayci, T; Demirbag, S; Eyi, YE; Gul, H; Kaldirim, U; Korkmaz, A; Macit, E; Oter, S; Ozler, M; Oztas, E; Topal, T; Toygar, M; Uysal, B; Yaman, H; Yildirim, AO, 2012)
" In order to examine the involvement of nitric oxide (NO) on stress-induced neurobehavioral changes and the concomitant alterations of neuroendocrinological factors, we studied the effects of the nonselective NOS inhibitor, N(ω)-Nitro L-arginine methyl ester hydrochloride (L-NAME) and the specific neuronal NOS inhibitor, 7-nitroindazole (7-NI) on restraint stress-induced anxiety in the elevated plus maze (EPM) test and biochemical analysis."3.78The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat. ( Her, S; Joung, HY; Jung, EY; Kim, K; Lee, MS; Shim, I, 2012)
"Effects of nitrates NaNO(3), KNO(3), Mg(NO(3)) 2 on animals (Wistar rats) were studied on the basis of the experimental model of ischemic stroke induced by the occlusion of two carotid arteries."3.78[The effect of nitrates on the outcome of acute experimental ischemic stroke]. ( Krushinskiĭ, AL; Kuzenkov, VS; Reutov, VP, 2012)
"The IOP lowering effects of NCX 139, a new chemical entity comprising latanoprost amide and a NO-donating moiety, were compared to those of the respective des-nitro analog in in vitro assays and in rabbit and dog models of ocular hypertension."3.77A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs. ( Batugo, M; Borghi, V; Brambilla, S; Carreiro, ST; Chiroli, V; Chong, WK; Gale, DC; Guzzetta, M; Impagnatiello, F; Krauss, AH; Ongini, E; Prasanna, G, 2011)
"We designed the present study to evaluate the efficacy of melatonin (M) on the severity of necrotizing enterocolitis (NEC) in a neonatal rat model."3.77Melatonin ameliorates necrotizing enterocolitis in a neonatal rat model. ( Gundogdu, G; Guven, A; Korkmaz, A; Oztas, E; Ozturk, H; Uysal, B, 2011)
"Specific dietary polyphenols, in particular quercetin and theaflavin, may attenuate atherosclerosis in ApoE(-/-) gene-knockout mice by alleviating inflammation, improving NO bioavailability, and inducing heme oxygenase-1."3.76Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction. ( Croft, KD; Hime, N; Hodgson, JM; Loke, WM; Magat, M; McKinley, AJ; Proudfoot, JM; Stocker, R, 2010)
" To clarify the role of NO in inflammation, we studied carrageenin-induced pleurisy in rats treated with an NO donor (NOC-18), a substrate for NO formation (L-arginine), and/or an NO synthase inhibitor (S-(2-aminoethyl) isothiourea or N(G)-nitro-L-arginine)."3.76Involvement of nitric oxide in a rat model of carrageenin-induced pleurisy. ( Asai, Y; Inoue, T; Iwata, M; Suzuki, S; Takagi, K, 2010)
" Synthesized compounds shown significant anti-inflammatory activity comparable to that of Diclofenac sodium in the carrageenan-induced rat paw edema test and all of the compounds were found to be equipotent to Diclofenac sodium in the acetic acid induced writhing analgesic model."3.76Synthesis and pharmacological evaluation of novel 1-(2-(benzoyl-substituted-2-phenyl-1H-indol-5-carbony) hydrazinyloxy) vinyl nitrate derivatives as potent non-ulcerogenic, analgesic and anti-inflammatory agents. ( Bhandari, SV; Bothara, KG; Burange, PJ; Dhoot, NS; Mokale, VJ; Naik, JB; Raut, MK, 2010)
" Treatment with simvastatin attenuated goblet cell hyperplasia, arginase-1 protein expression, and total arginase enzyme activity, but it did not alter airway hydroxyproline content or transforming growth factor-β1."3.76Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? ( Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA, 2010)
"Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by autonomic failure, parkinsonism, cerebellar ataxia, and oligodendrocytic accumulation of alpha-synuclein (alphasyn)."3.75Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. ( Adame, A; Inglis, C; Lee, PH; Mante, M; Masliah, E; Rockenstein, E; Stefanova, N; Ubhi, K; Wenning, GK, 2009)
"Population studies indicate that moderate hyperbilirubinemia is associated with reduced incidence of cardiovascular diseases, including hypertension."3.75Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice. ( Granger, JP; Stec, DE; Vera, T, 2009)
"Study hemodynamic pattern and lipoperoxidation during methylene blue (MB) treatment on taurocholate - enterokinase induced acute pancreatitis (AP)."3.74Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model. ( Baldo, CF; Ceneviva, R; Evora, PR; Meirelles, RF; Viaro, F, 2008)
" The present study is aimed to investigate the effect of L-arginine (as a natural NO donor) supplementation on NO metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial NO production."3.74L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia. ( Haghjooy Javanmard, S; Monajemi, A; Nematbakhsh, M, 2008)
"These results suggest that pretreatment with atorvastatin attenuates APE-induced pulmonary hypertension and increases 24-hr survival rate by mechanisms that result in attenuated increases in lung activated MMP-9 after APE."3.74Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9. ( Alves-Filho, JC; Cunha, FQ; Figueiredo-Lopes, L; Gerlach, RF; Semprini, MC; Souza-Costa, DC; Tanus-Santos, JE, 2007)
"To evaluate the effect of topically administered ascorbic acid on experimentally induced corneal neovascularization in the rat model."3.74Inhibition of corneal angiogenesis by ascorbic acid in the rat model. ( Conway, MD; DellaCroce, JT; Kivilcim, M; Morales, AM; Peyman, GA, 2007)
"Previous studies indicate that adenosine supplementation or nitric oxide synthase (NOS) inhibition during reperfusion exert protective effects against myocardial ischemia-reperfusion (I/R) injury."3.74Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury. ( Bouhaddi, M; Davani, S; Kantelip, JP; Reyssie, H; Rochette, L; Royer, B; Vergely, C, 2007)
" The aim of this study was to assess the effects of simvastatin on rats with TAA-induced acute liver damage and hepatic encephalopathy."3.74Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy. ( Chan, CY; Chang, FY; Chen, YC; Chu, CJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Wang, SS, 2008)
"Sepsis is an arginine-deficient state and is associated with overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS)."3.74The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model. ( Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S, 2008)
" The evolution of systolic blood pressure was followed by weekly measurements, and morphological variables, proteinuria, plasma nitrates plus nitrites (NOx) and thiobarbituric acid reactive substances (TBARS), liver oxidative stress markers and endothelial function were determined at the end of the experimental period."3.73Effects of chronic quercetin treatment in experimental renovascular hypertension. ( Bermejo, A; Duarte, J; Galisteo, M; García-Saura, MF; Vargas, F; Villar, IC; Zarzuelo, A, 2005)
"To investigate the systemic, pulmonary, and hepatosplanchnic hemodynamic and metabolic effects of delayed treatment with ethyl pyruvate in a long-term porcine model of hyperdynamic endotoxemia."3.73Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia. ( Albicini, M; Asfar, P; Bracht, H; Brückner, UB; Ehrmann, U; Fink, MP; Hauser, B; Kick, J; Radermacher, P; Vogt, J; Wachter, U, 2005)
"To evaluate the potential of S-nitroso-N-acetylcysteine (SNAC) in inhibition of lipid peroxidation and the effect of oral SNAC administration in the prevention of nonalcoholic fatty liver disease (NAFLD) in an animal model."3.73Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats. ( Abdalla, DS; Alves, VA; Carrilho, FJ; de Lima, VM; de Oliveira, CP; de Oliveira, MG; Laurindo, FR; Lopasso, FP; Simplicio, FI; Yuahasi, K, 2006)
"To assess the antioxidant effects of atorvastatin (atorva) on dexamethasone (dex)-induced hypertension, 60 male Sprague-Dawley rats were treated with atorva 30 mg/kg/day or tap water for 15 days."3.73Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat. ( Huang, TG; Mondo, CK; Su, JZ; Yang, WS, 2006)
" Using the hypoxia marker pimonidazole, we now provide immunohistochemical evidence that in the most frequently used animal model system of inbred mice Mtb-induced granulomas, even after more than one year of aerogenic infection, are not severely hypoxic."3.73Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. ( Aly, S; Bange, FC; Brandau, S; Ehlers, S; Keller, C; Malm, S; Malzan, A; Wagner, K, 2006)
"This study, in a porcine model of renal ischaemia-reperfusion injury, shows the benefits of methylprednisolone pretreatment in enhancing urinary nitrate levels indicative of vascular eNOS activity and the reduction of urinary beta-NAG levels, which represent subclinical renal injury."3.73Methylprednisolone increases urinary nitrate concentrations and reduces subclinical renal injury during infrarenal aortic ischemia reperfusion. ( Armstrong, MA; Baker, RC; Campbell, FC; D'Sa, AA; McBride, WT; McClean, E; O'Rourke, D; Young, IS, 2006)
" Body weight, urinary pyridinoline (Pyr), deoxypyridinoline (DPyr) corrected for urinary creatinine, serum nitrite/nitrate concentrations and whole body and femoral bone mineral density (BMD) were measured."3.72The effects of hyaluronan on bone resorption and bone mineral density in a rat model of estrogen deficiency-induced osteopenia. ( Istok, R; Rovenský, J; Stancíková, M; Svík, K; Velebný, V, 2004)
"The expression of HO-1 and iNOS in aorta increased with the SBP elevation during the development of SHR and was attenuated when the hypertension was lowered with the vasodilator hydralazine."3.72The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats. ( Chen, JJ; Cheng, PY; Yen, MH, 2004)
"To clarify the role of nitric oxide (NO) in the pathogenesis of seizures in susceptible EL mice, we investigated effects of three drugs potentially related to NO production, MK-801, dantrolene, and FK506, on convulsive seizures and brain NO metabolites (NOx)."3.71Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice. ( Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M, 2001)
" The pharmacological profile of n-acetylcysteine (NAC), a free radical scavenger, was evaluated in an experimental model of lung injury (carrageenan-induced pleurisy)."3.71Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat. ( Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I, 2001)
"We conclude that hypoxia-induced HTN is associated with depressed NO production and can be mitigated by L-arginine supplementation."3.70Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension. ( Bemanian, S; Kivlighn, SD; Ni, Z; Vaziri, ND, 1998)
" Here we investigated whether in vivo N-acetylcysteine treatment inhibits cellular injury in macrophages collected from rats subjected to zymosan-induced shock."3.70Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S, 1999)
" Thus, the objective of this study was to assess the role of iNOS in modulating neutrophil (PMN) extravasation in an oyster glycogen-induced model of acute peritonitis in rats."3.70Role of inducible nitric oxide synthase in leukocyte extravasation in vivo. ( Cockrell, A; Gray, L; Grisham, MB; Jourd'heuil, D; Kawachi, S; Laroux, FS; Van der Heyde, H, 1999)
" In vivo treatment with ip administration of 3-aminobenzamide (10 mg/kg, 1 and 6 hrs after zymosan injection) or nicotinamide (50 mg/kg, 1 and 6 hrs after zymosan injection) significantly decreased mortality, inhibited the development of peritonitis, and reduced peroxynitrite formation."3.70Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S; Sottile, A; Teti, D; Zingarelli, B, 1999)
" The current study was designed to investigate the protective effect of melatonin, a radical scavenger and antioxidant, on non-septic shock induced by zymosan in the rat."3.70Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. ( Caputi, AP; Cuzzocrea, S; El-Sokkary, GH; Hassanein, AF; Reiter, RJ; Tan, DX, 1999)
"Hyperhomocysteinemia (HH) is an independent risk factor for atherosclerosis, including peripheral arterial occlusive disease (PAOD)."3.70Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia. ( Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S, 2000)
"To investigate the role of carbon monoxide (CO) in the pathogenesis of asthma."3.70[Evidence of increased endogenous carbon monoxide production in asthma]. ( Jiang, D; Li, H; Shi, Y, 1999)
" In order to evaluate the participation of nitric oxide and superoxide in such diseases, we examined the expression of nitric oxide synthase (NOS) and superoxide dismutase (SOD) as well as their activities in whole excised colons of rats with colitis induced by intralumenal administration of 2,4,6-trinitrobenzenesulfonic acid."3.69Induction of nitric oxide synthase and concomitant suppression of superoxide dismutases in experimental colitis in rats. ( Fujii, J; Nakamura, M; Seo, HG; Suzuki, K; Takata, I; Taniguchi, N; Tatsumi, H, 1995)
" A decrease in the production and bioavailability of NO is a hallmark of many major chronic diseases including hypertension, ischaemia-reperfusion injury, atherosclerosis and diabetes."2.53Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases. ( Lundberg, JO; Omar, SA; Webb, AJ; Weitzberg, E, 2016)
"Unhealthy dietary habits contribute to the increasing incidence of metabolic syndrome and type 2 diabetes (T2D), which is accompanied by oxidative stress, compromised nitric oxide (NO) bioavailability and increased cardiovascular risk."1.56Head-to-head comparison of inorganic nitrate and metformin in a mouse model of cardiometabolic disease. ( Andersson, DC; Carlström, M; Cordero-Herrera, I; Guimarães, DD; Han, H; Lundberg, JO; McCann Haworth, S; Moretti, C; Uribe Gonzalez, AE; Weitzberg, E; Zhuge, Z, 2020)
"Levosimendan was administered after ROSC with a loading dose of 10 μg/kg and then infused at 0."1.56Synergistic Effects of Moderate Therapeutic Hypothermia and Levosimendan on Cardiac Function and Survival After Asphyxia-Induced Cardiac Arrest in Rats. ( Chang, WT; Chen, WJ; Huang, CH; Tsai, MS; Wang, CH, 2020)
"Maternal undernutrition is known to reduce glomerular number but it may also affect tubulointerstitium, capillary density, and response to oxidative stress."1.51Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring. ( Abe, T; Awazu, M; Hashiguchi, A; Hida, M, 2019)
"Corneal neovascularization was evaluated at 3, 4, 6, 8, 10, and 35 days after injury using digital photography, fluorescein angiography, gelatin perfusion with fluorescence vascular imaging, immunofluorescence staining, and molecular analysis."1.51Protective Effect of TLR4 Ablation against Corneal Neovascularization following Chemical Burn in a Mouse Model. ( Azrad-Lebovitz, T; Brookman, M; Friedman, M; Goldenberg-Cohen, N; Hochhauser, E; Marianayagam, NJ; Michowiz, S; Morzaev, D; Nicholson, JD; Zahavi, A, 2019)
"Moreover, MN-08 also alleviated cerebral vasospasm in a cisterna magna single-injection model in rabbits."1.51The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models. ( Guo, B; Han, Y; Ju, J; Li, N; Li, S; Liu, Z; Luo, F; Mak, S; Sun, Y; Wang, Y; Wu, L; Yang, X; Zhang, G; Zhang, Z; Zhou, Q; Zhu, Z, 2019)
"Ischemia was followed by a significant increase in muscle myeloperoxidase activity, as well as interleukin-6 and thiobarbituric acid reactive substances species levels."1.48N-acetylcysteine effects on a murine model of chronic critical limb ischemia. ( Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F, 2018)
"Dimethyl fumarate (DMF) is an important agent against inflammatory response and reactive species in CNS disorders."1.48Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis. ( Barichello, T; da Rosa, N; Danielski, LG; de Oliveira Junior, AN; de Souza Goldim, MP; Florentino, D; Fortunato, JJ; Giustina, AD; Gomes, ML; Laurentino, AO; Mathias, K; Moreira, AP; Petronilho, F; Schuck, PF; Steckert, AV; Trombetta, T; Zarbato, GF, 2018)
"Background Periodontitis is an inflammatory disease accompanied by alveolar bone loss and progressive inflammation without pain."1.46CXCR4 signaling in macrophages contributes to periodontal mechanical hypersensitivity in Porphyromonas gingivalis-induced periodontitis in mice. ( Honda, K; Iwata, K; Kamio, N; Nagashima, H; Sato, S; Shinoda, M; Sugano, N; Suzuki, T; Watanabe, M, 2017)
"Ischaemia was induced by 90-minutes middle cerebral artery occlusion (MCAO) followed by 24 hours of reperfusion."1.46Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke. ( Darabi, S; Mohammadi, MT, 2017)
"Fragile X syndrome is the most common genetic cause of mental disability."1.43An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability. ( Calvo-Medina, R; de Diego-Otero, Y; el Bekay, R; Garcia-Guirado, F; Lima-Cabello, E; Perez-Costillas, L; Quintero-Navarro, C; Sanchez-Salido, L, 2016)
" Dosing of mice with ND8008 (127."1.43A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics. ( Cai, C; Gong, L; Gu, H; Guo, L; Li, H; Shi, Y; Song, Z; Sun, H; Tong, Y; Wei, C; Yang, L; Yang, Y; Zeng, H; Zou, Q, 2016)
"Acute kidney injury is usually associated with distant organ dysfunction."1.43Distant effects of unilateral renal ischemia/reperfusion on contralateral kidney but not lung in rats: the roles of ROS and iNOS. ( Fatemikia, H; Karimi, Z; Ketabchi, F; Moosavi, SM, 2016)
" A reduction in NO bioavailability in early life may contribute to the initiation of glomerular and tubular dysfunction that promotes development and progression of hypertension in offspring with a congenital nephron deficit, including those with a SFK."1.43Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney. ( Booth, LC; Denton, KM; Easton, LK; Head, GA; Moritz, KM; Schlaich, MP; Singh, RR, 2016)
"Reduction in nitric oxide (NO) production and bioavailability contribute to the pathogenesis of type 2 diabetes."1.42Dietary nitrate improves glucose tolerance and lipid profile in an animal model of hyperglycemia. ( Ghanbari, M; Ghasemi, A; Jeddi, S; Kazerouni, F; Khalifi, S; Rahimipour, A, 2015)
"Portal hypertension is a common complication of liver cirrhosis and significantly increases mortality and morbidity."1.42Thalidomide ameliorates portal hypertension via nitric oxide synthase independent reduced systolic blood pressure. ( Korshunov, VA; Maluccio, MA; Skill, NJ; Theodorakis, NG; Wang, YN, 2015)
" Further studies evaluating longer-duration nitrite therapy and/or additional nitrite dosing strategies are warranted to more fully evaluate the therapeutic potential of nitrite therapy in peripheral vascular disease."1.42Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome. ( Bradley, JM; Brewster, LP; Calvert, JW; Chang, CC; Goodchild, TT; Islam, KN; Lefer, DJ; Pipinos, II; Polhemus, DJ; Tao, YX, 2015)
"The experimental model of pleurisy was induced in mice by a single intrapleural injection of carrageenan (1 %)."1.40Croton antisyphiliticus Mart. attenuates the inflammatory response to carrageenan-induced pleurisy in mice. ( de Carvalho, FK; Dos Reis, GO; Fröde, TS; Heller, M; Micke, GA; Pizzolatti, MG; Vicente, G, 2014)
"Colitis was induced in mice by administrating dextran sulfate sodium (DSS) with concurrent administration of nitrite (1 mM) or nitrate (10 mM) in the drinking water for 7 days."1.40Preventive and therapeutic effects of nitrite supplementation in experimental inflammatory bowel disease. ( Borniquel, S; Holm, L; Jädert, C; Lundberg, JO; Phillipson, M, 2014)
"Procarbazine (P) is an effective chemotherapeutic drug especially used in lymphoma treatment; however testicular toxicity is a limiting factor."1.40The effect of melatonin on procarbazine induced testicular toxicity on rats. ( Akgül, EÖ; Alp, BF; Babacan, O; Erdem, O; Gulgun, M; Kesik, V; Korkmazer, N; Malkoç, E; Poyrazoglu, Y; Saldır, M; Yiğit, N, 2014)
"Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes."1.39Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. ( Gauvreau, GM; Grasemann, H; Inman, MD; Khanna, N; North, ML; Scott, JA, 2013)
"Endotoxic shock was induced by lipopolysaccharide (LPS) in male Balb/c mice."1.39Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock. ( Amezcua-Guerra, LM; Argueta, I; Bojalil, R; Bolaños, L; Camacho-Villegas, TA; García-Ubbelohde, WJ; Licea-Navarro, AF; Márquez-Velasco, R; Mata-González, MT; Paniagua-Solís, JF; Sánchez-Castrejón, E; Sánchez-Muñoz, F; Yee, Y, 2013)
"Mortality of patients with acute liver failure (ALF) is still unacceptably high."1.39Evaluation of the Hepa Wash® treatment in pigs with acute liver failure. ( Al-Chalabi, A; Huber, W; Kreymann, B; Luppa, P; Matevossian, E; Nairz, E; Neiss, A; Perren, A; Radermacher, P; Schimmel, P; Schmid, RM; Schreiber, C; Schuster, T; V Thaden, AK; Yang, Z, 2013)
"Muscimol was administered twice on d14 and twice on d15 (1 h prior to each lipopolysaccharide injection; 0."1.39Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide. ( Dehpour, AR; Fakhraei, N; Gharedaghi, MH; Javadi-Paydar, M; Javadian, P; Salehi-Sadaghiani, M; Tavangar, SM; Yousefzadeh-Fard, Y, 2013)
"Vancomycin was treated to VSSA and VRSA infected mice at similar dose, respectively, for 10 days."1.38Staphylococcus aureus infection induced redox signaling and DNA fragmentation in T-lymphocytes: possible ameliorative role of nanoconjugated vancomycin. ( Chakraborty, SP; Chattopadhyay, S; Das, S; Dash, SK; Pramanik, P; Roy, S; Tripathy, S, 2012)
"Acute lung injury is still a significant clinical problem with a high mortality rate and there are few effective therapies in clinic."1.38Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB. ( Chen, L; Gao, M; Jiang, W; Kou, J; Li, J; Shao, F; Sun, Q; Wang, J; Yu, B, 2012)
"Sodium nitrite treatment reduced SBP in 2K1C rats (P < 0."1.38Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension. ( Amaral, JH; Costa-Filho, AJ; Marçal, DM; Montenegro, MF; Palei, AC; Pinheiro, LC; Tanus-Santos, JE, 2012)
"Acute lung injury was associated with a higher degree of pulmonary HIF-1α and iNOS expression as well as apoptosis in the lungs."1.38Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats. ( Hu, R; Huang, Y; Jiang, H; Li, QF; Xu, H, 2012)
"Cepharanthine (CE) is a plant alkaloid that possesses bioactive properties, with various known actions."1.37Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation. ( Hagiwara, S; Hasegawa, A; Koga, H; Kudo, K; Kusaka, J; Noguchi, T, 2011)
"Sepsis is a major health threat that remains refractory to treatment."1.37ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury. ( Goto, K; Hagiwara, S; Iwasaka, H; Koga, H; Kusaka, J; Noguchi, T; Uchida, T; Yokoi, I, 2011)
"Heat stroke is a condition characterized by high body temperature that can lead to hemorrhage and necrosis in multiple organs."1.37Danaparoid sodium attenuates the effects of heat stress. ( Hagiwara, S; Iwasaka, H; Matsumoto, S; Mizunaga, S; Nishida, T; Noguchi, T; Saikawa, T; Shingu, C; Uchida, T, 2011)
"Reduced bioavailability of endogenous nitric oxide (NO) is a central pathophysiological event in hypertension and other cardiovascular diseases."1.37Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension. ( Carlström, M; Hezel, M; Larsson, E; Lundberg, JO; Persson, AE; Scheffer, PG; Teerlink, T; Weitzberg, E, 2011)
"We used a murine model of arrhythmogenic right ventricular cardiomyopathy (ARVC) to test whether reducing ventricular load prevents or slows development of this cardiomyopathy."1.37Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice. ( Breithardt, G; Coronel, R; de Bakker, JM; Ebnet, K; Fabritz, L; Fortmueller, L; Franke, WW; Hoogendijk, MG; Kirchhof, P; Kreienkamp, N; Laakmann, S; Levkau, B; Noppinger, PR; Piccini, I; Pieperhoff, S; Scicluna, BP; van Amersfoorth, SC; Wichter, T; Witt, H; Wolf, S, 2011)
"Ocular hypertension was induced by unilaterally cauterizing three episcleral vessels and the unoperated eye served as control."1.37Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. ( Aslan, M; Batinic-Haberle, I; Cort, A; Dogan, S; Ozturk, N; Spasojevic, I; Unal, M; Yargicoglu, P, 2011)
" Nevertheless, vasopressin (AVP) release decreased in a dose-response manner in the early phase of sepsis."1.37Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis. ( Faccioli, LH; Martins, TF; Rocha, MJ; Sorgi, CA, 2011)
"The pathogenesis of nonalcoholic steatohepatitis (NASH) is still unclear."1.36Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model. ( Fujita, K; Inamori, M; Iwasaki, T; Kirikoshi, H; Maeyama, S; Nakajima, A; Nozaki, Y; Saito, S; Takahashi, H; Terauchi, Y; Wada, K; Yoneda, M, 2010)
" Our data suggest that the effect of the sex of the animal on NOS activity and expression is different in the three regions of the SHR kidney and supports the hypothesis that male SHR have lower NO bioavailability compared with females."1.36Renal NOS activity, expression, and localization in male and female spontaneously hypertensive rats. ( Hyndman, KA; Pardieck, JL; Pollock, JS; Sullivan, JC, 2010)
"Astaxanthine treatment significantly decreased hepatic conversion of XDH to XO and tissue protein carbonyl levels following IR injury."1.36Effect of astaxanthin on hepatocellular injury following ischemia/reperfusion. ( Aslan, M; Cort, A; Curek, GD; Demir, N; Elpek, GO; Ozturk, S; Savas, B; Yucel, G, 2010)
"Lung, liver, and bone cancer mortality rate ratios in the MPA worker cohort were compared to those seen in beagle dogs, and models of the excess relative risk of lung, liver, and bone cancer mortality from the MPA worker cohort were applied to data from life-span studies of beagle dogs."1.36Lung, liver and bone cancer mortality after plutonium exposure in beagle dogs and nuclear workers. ( Frey, GD; Hoel, DG; Lackland, D; Mohr, LC; Wilson, DA, 2010)
"Post-treatment with magnolol significantly attenuated the deleterious haemodynamic changes (e."1.36Beneficial effects of magnolol in a rodent model of endotoxin shock. ( Cheng, PY; Ke, TH; Kung, CW; Peng, YJ; Tsai, YC; Wang, JJ; Yen, MH, 2010)
"Indomethacin treatment significantly decreased cotton pellet implantation induced white blood cell count elevation and immune cells infiltration in epididymal white adipose tissue."1.36Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model. ( Chen, W; Cheng, JT; Cheng, KC; Shen, KH; Wu, HT; Yeh, CH, 2010)
"Although trauma-hemorrhage produces tissue hypoxia, systemic inflammatory response and organ dysfunction, the mechanisms responsible for these alterations are not clear."1.35Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury. ( Bland, KI; Chaudry, IH; Choudhry, MA; Hsu, JT; Kan, WH; Raju, R; Schwacha, MG, 2008)
" Because we have previously described that arginase affects NOx content and interferes with the activation of NF-kappaB in lung epithelial cells, the goal of this study was to investigate the impact of arginase inhibition on the bioavailability of NO and the implications for NF-kappaB activation and inflammation in a mouse model of allergic airway disease."1.35Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. ( Ckless, K; Irvin, CG; Janssen-Heininger, YM; Kasahara, D; Lampert, A; Lundblad, LK; Norton, R; Poynter, ME; Reiss, J; van der Vliet, A, 2008)
"Inflammation is a typical reaction to infection."1.35Hyperthermia amplifies brain cytokine and reactive oxygen species response in a model of perinatal inflammation. ( Dow, KE; Flavin, MP; Wang, W, 2008)
"Smoke inhalation injury is often complicated with pneumonia, which frequently leads to subsequent development of sepsis."1.35Role of neuronal nitric oxide synthase in ovine sepsis model. ( Enkhbaatar, P; Hamahata, A; Herndon, D; Jaroch, S; Jonkam, C; Lange, M; Nakano, Y; Traber, D; Traber, L; Wang, J, 2009)
"Using a carrageenan-induced thermal hyperalgesia model, we evaluated the effect of C-PC on nociception by measuring paw withdrawal latency."1.35Antiinflammatory and antihyperalgesic activity of C-phycocyanin. ( Cheng, SN; Chou, TC; Kuo, YL; Shih, CM; Wong, CS, 2009)
"Hypercholesterolemia is a major risk factor for the development and progression of cardiovascular diseases including atherosclerosis."1.35Suppression of diet-induced hypercholesterolemia by scutellarin in rats. ( Chan, SW; Chen, SL; Cheng, HL; Guo, DJ; Li, Q; Wu, JH, 2009)
"Hyperglycemia is frequently observed in nondiabetic patients during acute illness."1.35Hyperglycemia contributes to cardiac dysfunction in a lipopolysaccharide-induced systemic inflammation model. ( Asai, N; Hagiwara, S; Hasegawa, A; Iwasaka, H; Noguchi, T, 2009)
"gabapentin was studied by isobolographic analysis."1.35Antinociceptive effects of NCX-701 (nitro-paracetamol) in neuropathic rats: enhancement of antinociception by co-administration with gabapentin. ( Curros-Criado, MM; Herrero, JF, 2009)
"Melatonin (MT) has direct and indirect free radical detoxifying activity."1.35Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia. ( Fu, JH; Pan, L; Wei, B; Xu, W; Xue, XD; Zhou, P, 2009)
"Ozone treatment significantly reduced the severity of NEC by modulating antioxidative defense and antiinflammatory protection in our experimental animal model."1.35Medical ozone therapy reduces oxidative stress and intestinal damage in an experimental model of necrotizing enterocolitis in neonatal rats. ( Gundogdu, G; Guven, A; Korkmaz, A; Oztas, E; Ozturk, H; Uysal, B; Vurucu, S, 2009)
"Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental."1.35An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage. ( Barclay, D; Billiar, TR; Clermont, G; Ghuma, A; Gomez, H; Gordon, L; Hermus, L; Kim, HK; Namas, R; Ochoa, J; Peitzman, A; Pinsky, MR; Polanco, P; Puyana, JC; Rosengart, MR; Torres, A; Vodovotz, Y; Zamora, R; Zenker, S, 2009)
"Pendred syndrome is due to loss-of-function mutations of Slc26a4, which codes for the HCO(3)(-) transporter pendrin."1.35Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model. ( Singh, R; Wangemann, P, 2008)
" The present study investigated the importance of endogenous prostaglandin production and nitric oxide (NO) in the renal haemodynamic and excretory responses to ischaemia-reperfusion both normally and in the hypertensive state by chronic administration of cyclo-oxygenase (COX) inhibitors."1.35Renal functional responses to ischaemia-reperfusion injury in normotensive and hypertensive rats following non-selective and selective cyclo-oxygenase inhibition with nitric oxide donation. ( Johns, EJ; Knight, S, 2008)
"Melatonin-treated animals had better neurologic function than those of the I/R group."1.35Effects of melatonin on ischemic spinal cord injury caused by aortic cross clamping in rabbits. ( Kardeş, O; Korkmaz, A; Omeroğlu, S; Oyar, EO, 2008)
"Atherosclerosis is enhanced in arterial segments exposed to disturbed flow."1.35Beneficial effects of low doses of red wine consumption on perturbed shear stress-induced atherogenesis. ( Balestrieri, ML; Crimi, E; D'Armiento, FP; De Rosa, G; Lerman, LO; Napoli, C; Schiano, C; Servillo, L; Sica, V, 2008)
"Biliary cirrhosis was accompanied with a decrease in baseline perfusion pressure in mesenteric vascular bed (P < 0."1.35Opioid receptor blockade improves mesenteric responsiveness in biliary cirrhosis. ( Dehpour, AR; Ebrahimkhani, MR; Kiani, S; Merat, S; Moezi, L, 2008)
"Endotoxemia was induced by an infusion of lipopolysac-charide (LPS) after HDL or LDL administration."1.34High-density lipoprotein prevents organ damage in endotoxemia. ( Chao, YF; Chen, HI; Harn, HJ; Lee, RP; Lin, CC; Lin, NT, 2007)
"LPS induced cytotoxic brain swelling and maintained anatomical integrity of the blood-brain barrier."1.34Endotoxemia produces coma and brain swelling in bile duct ligated rats. ( Brooks, HF; Davies, C; Davies, NA; Harry, D; Hodges, SJ; Jalan, R; Mani, AR; Moore, KP; Shawcross, DL; Stadlbauer, V; Williams, R; Wright, G; Zou, Z; Zwingmann, C, 2007)
"Pyrrolidine dithiocarbamate treatment significantly reduced the MDA and NO levels, and increased the GSH levels in the lung parenchyma, biochemically (p < 0."1.34Pyrrolidine dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model. ( Aytekin, FO; Bir, F; Erdem, E; Kabay, B; Ozden, A; Sacar, M; Teke, Z; Yenisey, C, 2007)
"Melatonin was administered intraperitoneally with two different doses (20mg/kg or 40mg/kg) beginning 1h before HN2 application and continued every 12h for six replications."1.34Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. ( Korkmaz, A; Kurt, B; Oter, S; Reiter, RJ; Topal, T; Ucar, M; Yaren, H, 2007)
" During this study we investigated the alterations in NO synthesis and bioavailability in a model for dietary modulations of insulin sensitivity."1.34Nitric oxide bioavailability and not production is first altered during the onset of insulin resistance in sucrose-fed rats. ( Blouet, C; Huneau, JF; Mariotti, F; Mathe, V; Tome, D, 2007)
" Intraperitoneal injection of 20% water solution of L-arginine in dosage 200 mg per 100 g of an animal body mass have had aggravated an acute pancreatitis course; intravenous injection of 1% water solution of methylene blue in dosage 1 mg per 100 g of an animal body mass caused pancreatoprotective effect."1.33[Role of nitric oxide and lipid peroxidation in pathogenesis of acute experimental pancreatitis]. ( Fedorovich, AA; Krivoruchko, IA, 2005)
"Rosiglitazone or 15d-PGJ2 were administered to rats 10 mins or 2 h after permanent middle cerebral artery occlusion (MCAO)."1.33Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms. ( Boscá, L; Cárdenas, A; Castillo, J; Dávalos, A; Hurtado, O; Lizasoain, I; Lorenzo, P; Moro, MA; Pereira, MP; Serena, J; Vivancos, J, 2006)
"Treatment with ibuprofen, either before or after ETX, partly restored the elevated levels of nitrite/nitrate."1.33Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock. ( Akbulut, H; Ayar, A; Canbaz, M; Celik, I; Vural, P, 2005)
"Luteolin was found histologically to suppress inflammation in lung tissue, the development of C."1.33In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model. ( Leinonen, M; Saario, E; Saikku, P; Törmäkangas, L; Vuorela, H; Vuorela, P, 2005)
"CBDL rats show hypoxemia with intrapulmonary vasodilatation (IPVD), and are recognized as a model of hepatopulmonary syndrome (HPS), while PVL rats are normoxemic."1.33Arterial hypoxemia and intrapulmonary vasodilatation in rat models of portal hypertension. ( Akimoto, T; Kato, Y; Katsuta, Y; Komeichi, H; Miyamoto, A; Ohsuga, M; Satomura, K; Shimizu, S; Takano, T; Zhang, XJ, 2005)
"In a mouse model of platelet pulmonary thromboembolism, induced by the i."1.33A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression. ( Caracchini, R; Colucci, M; Giannini, S; Gresele, P; Guglielmini, G; Momi, S; Monopoli, A; Ongini, E; Rossiello, MR; Semeraro, N, 2005)
"Lower-limb ischemia is a major health problem."1.33Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb. ( Botti, C; Byrns, RE; de Nigris, F; de Rosa, G; Farzati, B; Fiore, A; Ignarro, LJ; Lerman, LO; Matarazzo, A; Napoli, C; Sica, G; Sica, V; Sumi, D; Williams-Ignarro, S, 2005)
"Sildenafil attenuates acute pulmonary embolism (APE)-induced pulmonary hypertension."1.33Hemodynamic effects of sildenafil interaction with a nitric oxide donor compound in a dog model of acute pulmonary embolism. ( Dias-Junior, CA; Tanus-Santos, JE, 2006)
"Metabolic syndrome is a cluster of metabolic diseases that in essence greatly promotes progression of atherosclerosis."1.33Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome. ( Haginaka, J; Kagota, S; Kunitomo, M; Nakamura, K; Yamaguchi, Y; Yoshikawa, N, 2006)
"In vehicle-treated rats, Trypanosoma cruzi infection increased the cardiac levels of TNF-alpha, IFN-gamma and IL-10, at day 9 post inoculation, and the TNF-alpha remained elevated until day 13."1.33Blockade of endothelin ET(A)/ET(B) receptors favors a role for endothelin during acute Trypanosoma cruzi infection in rats. ( Barcellos, L; Camargos, ER; Chiari, E; Huang, H; Machado, CR; Marques, CA; Rachid, MA; Tanowitz, HB; Teixeira, MM, 2006)
"Proteinuria was significantly lower in L-arginine-treated animals from week 24 onward (p<0."1.32Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure. ( Albrecht, EW; Smit-van Oosten, A; Stegeman, CA; van Goor, H, 2003)
" In conclusion, the chronic use of NAC inhibited MPO activity and lipid peroxidation, which resulted in reduction of apoptosis in lung in this CLP model."1.32The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. ( Avlan, D; Cinel, I; Cinel, L; Dikmengil, M; Koksel, O; Okcu, H; Oral, U; Ozdulger, A; Unlu, A, 2003)
"Four surrogate studies were performed in this assessment including fluoride uptake in sound enamel, enamel solubility reduction, fluoride bioavailability and animal caries."1.32Anticaries efficacy of a new dentifrice for hypersensitivity. ( Fisher, SW; Gambogi, RJ; Joziak, M; Tavss, EA, 2003)
"Treatment with rosiglitazone enhanced PPARgamma expression, improved endothelium-dependent vasodilatation, preserved P-VASP, suppressed gp91phox and iNOS expression, reduced superoxide and total NOx production, and inhibited nitrotyrosine formation."1.32Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. ( Batinic-Haberle, I; Christopher, TA; Gao, E; Liu, HR; Lopez, BL; Ma, XL; Ohlstein, EH; Tao, L; Teng, ZP; Willette, RN; Yue, TL, 2003)
"enalapril alone to enhance vascular effects, increase LV contractility and prevent unfavorable remodeling and are consistent with vascular delivery of exogenous NO."1.32A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. ( Condorelli, G; Del Soldato, P; Dieterle, T; Gu, Y; Iwanaga, Y; Ongini, E; Peterson, KL; Presotto, C; Ross, J, 2004)
"Pleurisy was induced by carrageenan (1%) treatment and the parameters were analyzed 4 and 48 h after."1.32Additional evidence of acute anti-inflammatory effects of cyclosporin A in a murine model of pleurisy. ( Fröde, TS; Medeiros, YS; Monguilhott Dalmarco, E, 2004)
"Pleurisy was induced by intrapleural injection of carrageenan in mice pre-treated or not with PK11195."1.32Involvement of steroids in anti-inflammatory effects of PK11195 in a murine model of pleurisy. ( da Silva, MB; Farges, RC; Fröde, TS, 2004)
"Agmatine is a primary amine formed by the decarboxylation of L-arginine synthesized in mammalian brain."1.32Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury. ( Cho, SW; Giffard, RG; Kim, JH; Lee, JE; Park, KA; Yenari, MA, 2004)
"Uric acid (UA) is a natural scavenger of ONOO(-) that is present at high levels in the sera of humans and other higher order primates relative to most lower mammals."1.31Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid. ( Hooper, DC; Kean, RB; Mikheeva, T; Scott, GS; Spitsin, SV, 2000)
"Both abdominal aortic aneurysms (AAAs) and inducible nitric oxide synthase (iNOS) are associated with inflammatory states, yet the relationship between NO production by iNOS and AAA development is unknown."1.31Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion. ( Carey, DJ; Elmore, JR; Franklin, DP; Han, DC; Johanning, JM, 2001)
"Tamoxifen has several potential mechanisms of action including inhibition of the release of excitatory amino acids (EAA) and nitric oxide synthase (NOS) activity."1.31Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat. ( Feustel, PJ; Kimelberg, HK; Mongin, AA; Osuka, K; Tranmer, BI, 2001)
"Cholestasis is associated with NO overproduction."1.31The role of the interaction between endogenous opioids and nitric oxide in the pathophysiology of ethanol-induced gastric damage in cholestatic rats. ( Akbari, MR; Dehpour, AR; Homayounfar, H; Mani, AR; Nahavandi, A, 2001)
"After 5 weeks, MRI showed right ventricular hypertrophy in MCT(+)/ACEI(-) rats."1.31Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats. ( Billiar, TR; Ho, C; Kanno, S; Lee, PC; Wu, YJ, 2001)
"Endotoxic shock was induced by administration of Escherichia coli endotoxin in rats."1.31Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents. ( Hake, PW; Malhotra, V; O'Connor, M; Sheehan, M; Wong, HR; Zingarelli, B, 2002)
" Chronic administration of L-NAME to rats induced reduced NO production and hypertension in both strains of rats."1.31Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats. ( Ishimura, N; Nakaya, Y; Takahashi, A; Takishita, E, 2002)
" Long-term administration (2 mo) of the selective NOS II inhibitor S-methylisothiourea (SMT) to rats with MI significantly improved cardiac function."1.31Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure. ( Fahas, L; Giaid, A; Hu, F; Saito, T; Shennib, H; Tayara, L, 2002)
"Hemorrhagic shock is associated with early vasomotor paralysis as well as with early derangements in the cellular metabolic status."1.30Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock. ( Szabó, C, 1998)
"Ventricular arrhythmia incidence during ischaemia and during reperfusion were related to the size of the involved region."1.28A modified model of global ischaemia: application to the study of syncytial mechanisms of arrhythmogenesis. ( Curtis, MJ; Ridley, PD; Yacoub, MH, 1992)

Research

Studies (476)

TimeframeStudies, this research(%)All Research%
pre-19904 (0.84)18.7374
1990's68 (14.29)18.2507
2000's223 (46.85)29.6817
2010's159 (33.40)24.3611
2020's22 (4.62)2.80

Authors

AuthorsStudies
Kaviani, A1
Khansari Nejad, N1
Akour, A1
AlMuhaissen, SA1
Nusair, MB1
Al-Tammemi, AB1
Mahmoud, NN1
Jalouqa, S1
Alrawashdeh, MN1
Shanahan, JP1
Moore, CM1
Kampf, JW1
Szymczak, NK1
Guo, J1
Wang, H6
Luo, Y2
An, H1
Zhang, Z6
Liu, G1
Li, J12
Metcalfe, GD1
Smith, TW1
Hippler, M1
Ayala Izurieta, JE1
Márquez, CO1
García, VJ1
Jara Santillán, CA1
Sisti, JM1
Pasqualotto, N1
Van Wittenberghe, S1
Delegido, J1
Kubo, Y2
Kitagawa, Y1
Miyazaki, T1
Sohda, M1
Yamaji, T1
Sakai, M1
Saeki, H1
Nemoto, K1
Oyama, T2
Muto, M1
Takeuchi, H1
Toh, Y1
Matsubara, H1
Mano, M1
Kono, K1
Kato, K2
Yoshida, M1
Kawakubo, H1
Booka, E1
Yamatsuji, T1
Kato, H2
Ito, Y1
Ishikawa, H1
Ishihara, R1
Tsushima, T1
Kawachi, H1
Kojima, T1
Kuribayashi, S1
Makino, T1
Matsuda, S1
Doki, Y1
Ma, P1
Tang, X1
Zhang, L7
Wang, X8
Wang, W8
Zhang, X8
Wang, S5
Zhou, N1
Dodd, J1
Jordan, R1
Makhlina, M1
Pesco Koplowitz, L1
Koplowitz, B1
Barnett, K1
Yang, WH1
Spana, C1
Buchanan, SW1
Mafa-Attoye, T1
Dunfield, K1
Thevathasan, NV1
Isaac, ME1
Wu, X4
Huang, JW1
Su, BK1
Yuan, L1
Zheng, WQ1
Zhang, H7
Zheng, YX1
Zhu, W1
Chou, PT1
Manso, AP1
De Morais, DC1
Yamamoto, K1
Owen, G1
de Carvalho, RM1
Palma-Dibb, RG1
Brown, JC1
Yang, S3
Mire, EF1
Miele, L1
Ochoa, A1
Zabaleta, J1
Katzmarzyk, PT1
Moi, CT1
Bhowmick, S1
Qureshi, M1
Wang, K2
Feng, B1
Yang, Y7
Chen, Y2
Wang, Y11
Yang, L3
Jiang, K2
James, TD1
Chaturvedi, V1
Postiglione, WM1
Chakraborty, RD1
Yu, B4
Tabiś, W1
Hameed, S1
Biniskos, N1
Jacobson, A1
Zhou, H4
Greven, M1
Ferry, VE1
Leighton, C1
Wu, F2
Lei, H2
Chen, G1
Chen, C3
Song, Y3
Cao, Z1
Zhang, C9
Zhou, J1
Lu, Y2
Pappone, C1
Santinelli, V1
Mecarocci, V1
Tondi, L1
Ciconte, G1
Manguso, F1
Sturla, F1
Vicedomini, G1
Micaglio, E1
Anastasia, L1
Pica, S1
Camporeale, A1
Lombardi, M1
Shieh, PB1
Elfring, G1
Trifillis, P1
Santos, C1
Peltz, SW1
Parsons, JA1
Apkon, S1
Darras, BT1
Campbell, C1
McDonald, CM1
Galaviz, KI1
Shah, NS1
Gutierrez, M1
Collins, LF1
Lahiri, CD1
Moran, CA1
Szabo, B1
Sumitani, J1
Rhodes, J1
Marconi, VC1
Nguyen, ML1
Cantos, VD1
Armstrong, WS1
Colasanti, JA1
Еlmahdy, MK1
Abdelaziz, RR1
Elmahdi, HS1
Suddek, GM1
Hu, J2
Tong, Y2
Shen, Z1
Li, Y7
Cheng, C1
Au, R1
Xu, F2
Liu, Y8
Zhu, L2
Shen, H2
Xue, K1
Chen, S2
Chai, J1
Yan, W2
Zhu, X2
Ji, D1
Wu, Y6
Liu, H6
Qutob, HMH1
Saad, RA1
Bali, H1
Osailan, A1
Jaber, J1
Alzahrani, E1
Alyami, J1
Elsayed, H1
Alserihi, R1
Shaikhomar, OA1
Divya, KM1
Savitha, DP1
Krishna, GA1
Dhanya, TM1
Mohanan, PV1
Shah, SF1
Jafry, AT1
Hussain, G1
Kazim, AH1
Ali, M1
Rivani, E1
Endraswari, PD1
Widodo, ADW1
Khalil, MR1
Guldberg, R1
Nørgård, BM1
Uldbjerg, N1
Wehberg, S1
Fowobaje, KR1
Mashood, LO1
Ekholuenetale, M1
Ibidoja, OJ1
Romagnoli, A1
D'Agostino, M1
Pavoni, E1
Ardiccioni, C1
Motta, S1
Crippa, P1
Biagetti, G1
Notarstefano, V1
Rexha, J1
Perta, N1
Barocci, S1
Costabile, BK1
Colasurdo, G1
Caucci, S1
Mencarelli, D1
Turchetti, C1
Farina, M1
Pierantoni, L1
La Teana, A1
Al Hadi, R1
Cicconardi, F1
Chinappi, M1
Trucchi, E1
Mancia, F1
Menzo, S1
Morozzo Della Rocca, B1
D'Annessa, I1
Di Marino, D1
Choya, A1
de Rivas, B1
Gutiérrez-Ortiz, JI1
López-Fonseca, R1
Xu, S2
Cheng, B1
Huang, Z3
Liu, T3
Jiang, L1
Guo, W2
Xiong, J1
Amirazodi, M1
Daryanoosh, F1
Mehrabi, A1
Gaeini, A1
Koushkie Jahromi, M1
Salesi, M1
Zarifkar, AH1
Studeny, P1
Netukova, M1
Nemcokova, M1
Klimesova, YM1
Krizova, D1
Kang, H1
Tao, Y1
Zhang, Q5
Sha, D1
Yao, J1
Gao, Y2
Liu, J5
Ji, L1
Shi, P1
Shi, C1
Wu, YL1
Wright, AI1
M El-Metwaly, N1
A Katouah, H1
El-Desouky, MG1
El-Bindary, AA1
El-Bindary, MA1
Kostakis, ID1
Raptis, DA1
Davidson, BR1
Iype, S1
Nasralla, D1
Imber, C1
Sharma, D1
Pissanou, T1
Pollok, JM1
Hughes, AM1
Sanderson, E1
Morris, T1
Ayorech, Z1
Tesli, M1
Ask, H1
Reichborn-Kjennerud, T1
Andreassen, OA1
Magnus, P1
Helgeland, Ø1
Johansson, S1
Njølstad, P1
Davey Smith, G1
Havdahl, A1
Howe, LD1
Davies, NM1
Amrillah, T1
Prasetio, A1
Supandi, AR1
Sidiq, DH1
Putra, FS1
Nugroho, MA1
Salsabilla, Z1
Azmi, R1
Grammatikopoulos, P1
Bouloumis, T1
Steinhauer, S1
Mironov, VS2
Bazhenova, TA2
Manakin, YV2
Yagubskii, EB2
Yakushev, IA1
Gilmutdinov, IF1
Simonov, SV1
Lan, K1
Yang, H2
Zheng, J2
Hu, H2
Zhu, T1
Zou, X1
Hu, B2
Olokede, O1
Wu, H1
Holtzapple, M1
Gungor, O1
Kose, M1
Ghaemi, R1
Acker, M1
Stosic, A1
Jacobs, R1
Selvaganapathy, PR1
Ludwig, N1
Yerneni, SS1
Azambuja, JH1
Pietrowska, M1
Widłak, P1
Hinck, CS1
Głuszko, A1
Szczepański, MJ1
Kärmer, T1
Kallinger, I1
Schulz, D1
Bauer, RJ1
Spanier, G1
Spoerl, S1
Meier, JK1
Ettl, T1
Razzo, BM1
Reichert, TE1
Hinck, AP1
Whiteside, TL1
Wei, ZL1
Juan, W1
Tong, D1
Juan, LX1
Sa, LY1
Jie, HFM1
Xiao, G1
Xiang, LG1
Jie, HM1
Xu, C2
Yu, DN1
Yao, ZX1
Bigdeli, F1
Gao, XM1
Cheng, X2
Li, JZ1
Zhang, JW1
Guan, ZJ1
Bu, Y1
Liu, KG1
Morsali, A1
Das, R1
Paul, R1
Parui, A1
Shrotri, A1
Atzori, C1
Lomachenko, KA1
Singh, AK1
Mondal, J1
Peter, SC1
Florimbio, AR1
Coughlin, LN1
Bauermeister, JA1
Young, SD1
Zimmerman, MA1
Walton, MA1
Bonar, EE1
Demir, D1
Balci, AB1
Kahraman, N1
Sunbul, SA1
Gucu, A1
Seker, IB1
Badem, S1
Yuksel, A1
Ozyazicioglu, AF1
Goncu, MT1
Deng, Z2
Luo, L2
Ong, SP1
Wang, C4
Xin, H1
Whittingham, MS1
Zhou, G1
Maemura, R1
Wakamatsu, M1
Matsumoto, K1
Sakaguchi, H1
Yoshida, N2
Hama, A1
Yoshida, T1
Miwata, S1
Kitazawa, H1
Narita, K1
Kataoka, S1
Ichikawa, D1
Hamada, M1
Taniguchi, R1
Suzuki, K2
Kawashima, N1
Nishikawa, E1
Narita, A1
Okuno, Y1
Nishio, N1
Kojima, S1
Morita, K1
Muramatsu, H1
Takahashi, Y1
Yirgu, A1
Mekonnen, Y1
Eyado, A1
Staropoli, A1
Vinale, F1
Zac, J1
Zac, S1
Pérez-Padilla, R1
Remigio-Luna, A1
Guzmán-Boulloud, N1
Gochicoa-Rangel, L1
Guzmán-Valderrábano, C1
Thirión-Romero, I1
Statsenko, ME1
Turkina, SV1
Barantsevich, ER1
Karakulova, YV1
Baranova, NS1
Morzhukhina, MV1
Wang, Q3
Gu, Y2
Qiao, L2
Pan, F1
Song, C1
Canetto, SS1
Entilli, L1
Cerbo, I1
Cipolletta, S1
Zhu, P1
Jiang, Y1
Wang, Z4
Xie, B1
Song, T1
Zhang, F1
Luo, A1
Li, S4
Xiong, X3
Han, J3
Peng, X2
Li, M1
Huang, L4
Chen, Q2
Fang, W1
Hou, Y2
Zhu, Y2
Ye, J2
Liu, L1
Islam, MR1
Sanderson, P1
Johansen, MP1
Payne, TE1
Naidu, R1
Cao, J1
Yang, J5
Niu, X1
Liu, X5
Zhai, Y1
Qiang, C1
Niu, Y1
Li, Z3
Dong, N1
Wen, B1
Ouyang, Z1
Zhang, Y8
Zhao, M2
Zhao, J2
Morici, P1
Rizzato, C1
Ghelardi, E1
Rossolini, GM1
Lupetti, A1
Gözüküçük, R1
Cakiroglu, B1
He, X1
Li, R1
Zhao, D2
Ji, X1
Fan, X1
Chen, J5
Zheng, D1
Xie, L1
Sun, S1
Cai, Z1
Liu, Q3
Ma, K1
Sun, X2
Drinkwater, JJ1
Davis, TME1
Turner, AW1
Davis, WA1
Suzuki, Y1
Mizuta, Y1
Mikagi, A1
Misawa-Suzuki, T1
Tsuchido, Y1
Sugaya, T1
Hashimoto, T1
Ema, K1
Hayashita, T1
Pan, W1
Gu, J1
Wang, J11
Xu, J4
Liang, D1
Xie, T1
Qiang, J1
Sun, Q3
Noguchi, K1
Sugaya, K1
Nishijima, S1
Sakanashi, M1
Kadekawa, K1
Ashitomi, K1
Okitsu, S1
Yamamoto, H2
Malikova, E1
Carlström, M6
Kmecova, Z1
Marusakova, M1
Zsigmondova, B1
Krenek, P1
Klimas, J1
Henrohn, D1
Awazu, M1
Abe, T1
Hashiguchi, A1
Hida, M1
Peleli, M2
Ferreira, DMS1
Tarnawski, L1
McCann Haworth, S2
Xuechen, L1
Zhuge, Z3
Newton, PT1
Massart, J1
Chagin, AS1
Olofsson, PS1
Ruas, JL1
Weitzberg, E8
Lundberg, JO9
Kosutova, P2
Mikolka, P2
Balentova, S2
Adamkov, M2
Mokra, D2
Cordero-Herrera, I1
Guimarães, DD2
Moretti, C1
Han, H1
Uribe Gonzalez, AE1
Andersson, DC1
Koka, S1
Xi, L1
Kukreja, RC1
Sanches-Lopes, JM1
Ferreira, GC2
Pinheiro, LC3
Kemp, R1
Tanus-Santos, JE7
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
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Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Remote Ischemic Preconditioning on the Postoperative Liver Function in Living Donor Hepatectomy: a Randomized Clinical Trial[NCT03386435]160 participants (Actual)Interventional2016-08-22Completed
Dietary Nitrate on Salivary Flow for Nasopharyngeal Carcinoma Patients Pre and Post Concurrent Chemo-radiation Therapy[NCT02854410]30 participants (Anticipated)Interventional2016-08-31Not yet recruiting
Phase 1 Study of the Safety and Pharmacokinetics of Perioperative IV L-carnitine Administration in Patients With Congenital Heart Disease With Increased Pulmonary Blood Flow[NCT01825369]Phase 10 participants (Actual)Interventional2014-12-31Withdrawn (stopped due to Changes to cardiac surgery program)
A Prospective, Randomized, Double-blind, Parallel, Placebo-controlled, Multi-center Study to Investigate the Efficacy and Safety of Apomivir® in Relieving Influenza Symptoms[NCT01677689]Phase 2196 participants (Anticipated)Interventional2018-09-01Not yet recruiting
Production of Fortified Biscuit With Chickpea and Crushed Peanut and Evaluating Its Effectiveness in Terms of Its Acceptability and Cognitive Performance: a Pilot Study Among Egyptian Primary School-aged Children[NCT05281146]80 participants (Actual)Interventional2018-11-26Completed
A Phase 2a Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura[NCT00877838]Phase 240 participants (Anticipated)Interventional2009-05-31Recruiting
NITRATE-OCT-CIN Trial: A Randomised, Double-blind, Placebo-controlled Study Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina (Sub-study of the NITRATE-OCT Trial)[NCT05544981]300 participants (Actual)Interventional2016-01-02Completed
Treatment of Multiple Sclerosis Using Over the Counter Inosine[NCT00067327]Phase 230 participants Interventional2002-02-28Completed
Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation: A Randomized, Double-blind, Controlled Trial[NCT05450328]Phase 2141 participants (Anticipated)Interventional2022-09-01Not yet recruiting
Effect of Combined Antihypertensive Therapy on Blood Pressure and Sexual Function in Patients With Essential Hypertension[NCT01238705]Phase 4280 participants (Anticipated)Interventional2008-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Delayed Recovery of Liver Function

The incidence of delayed recovery of hepatic function (DRHF) were used as surrogate parameters indicating the possible benefits of RIPC. DRHF was defined based on a proposal by the International Study Group of Liver Surgery, as follows: an impaired ability of the liver to maintain its synthetic, excretory, and detoxifying functions, which are characterized by an increased PT INR and concomitant hyperbilirubinemia (considering the normal limits of the local laboratory) on or after postoperative day 5. The normal upper limits of PT and bilirubin in our institutional laboratory were 1.30 INR and 1.2 mg/dL, respectively. If either the PT INR or serum bilirubin concentration was preoperatively elevated, DRHF was defined by an increasing PT INR and increasing serum bilirubin concentration on or after postoperative day 5 (compared with the values of the previous day). (NCT03386435)
Timeframe: postoperative 7 days

InterventionParticipants (Count of Participants)
RIPC5
Control0

Postopera The Maximal Aspartate Aminotransferase Level Within 7 Postoperative Days

The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal aspartate aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy. (NCT03386435)
Timeframe: within 7 days after operation

InterventionIU/L (Mean)
RIPC145
Control152

Postoperative Liver Regeneration

The postoperative liver regeneration index (LRI) at postoperative 1 month ) was used as surrogate parameters indicating the possible benefits of RIPC. The LRI was defined as [(VLR - VFLR)/VFLR)] × 100, where VLR is the volume of the liver remnant and VFLR is the volume of the future liver remnant. Liver volume was calculated by CT volumetry using 3-mm-thick dynamic CT images. The graft weight was subtracted from the total liver volume to define the future liver remnant. (NCT03386435)
Timeframe: 1 month

Interventionpercentage of liver volume (Mean)
RIPC83.3
Control94.9

The Maximal Alanine Aminotransferase Level Within 7 Postoperative Days

The serial assessments of routine laboratory values were used as early markers for postoperative liver function. The maximal alanine aminotransferase level within 7 postoperative days were assessed following RIPC in living donor hepatectomy (NCT03386435)
Timeframe: within 7 days after operation

InterventionIU/L (Mean)
RIPC148
Control152

Reviews

16 reviews available for nitrates and Disease Models, Animal

ArticleYear
    Biomaterial investigations in dentistry, 2021, Volume: 8, Issue:1

    Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes

2021
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
    Medicina clinica (English ed.), 2022, Dec-23, Volume: 159, Issue:12

    Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter

2022
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
[INVOLVEMENT OF NITRIC OXIDE CYNTHASE IN THE EARLY PHASE OF THE HEART ISCHEMIC PRECONDITIONING].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2016, Volume: 102, Issue:7

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Isc

2016
Nitrate and nitrite in the diet: how to assess their benefit and risk for human health.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:1

    Topics: Animals; Biomarkers; Diet; Disease Models, Animal; Humans; Meat Products; Neoplasms; Nitrates; Nitri

2015
NO-Rich Diet for Lifestyle-Related Diseases.
    Nutrients, 2015, Jun-17, Volume: 7, Issue:6

    Topics: Animals; Biological Availability; Chronic Disease; Diet; Disease Models, Animal; Fruit; Humans; Life

2015
Inorganic nitrite and nitrate: evidence to support consideration as dietary nutrients.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:8

    Topics: Animals; Cardiovascular Diseases; Cardiovascular System; Consumer Product Safety; Diet; Disease Mode

2015
Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases.
    Journal of internal medicine, 2016, Volume: 279, Issue:4

    Topics: Animals; Biological Availability; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Di

2016
    Obesity science & practice, 2016, Volume: 2, Issue:1

    Topics: Absorptiometry, Photon; Adult; Air Pollutants; Alkynes; Alleles; Animals; Anthracenes; Anthraquinone

2016
Nitric oxide releasing acetaminophen (nitroacetaminophen).
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35 Suppl 2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease M

2003
Drinking water and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Animals; Arsenic; Asbestos; Carcinogens; Chlorine Compounds; Disease Models, Animal; Disinfectants;

1997
Role of nitric oxide in endotoxic shock. An overview of recent advances.
    Annals of the New York Academy of Sciences, 1998, Jun-30, Volume: 851

    Topics: Anti-Inflammatory Agents; Disease Models, Animal; Enzyme Inhibitors; Gene Deletion; Humans; Nitrates

1998
Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species.
    Archives of biochemistry and biophysics, 1998, Aug-01, Volume: 356, Issue:1

    Topics: Animals; Disease Models, Animal; Humans; Nitrates; Nitric Oxide; Oxidative Stress; Reactive Oxygen S

1998
Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice.
    Environmental health perspectives, 1998, Volume: 106 Suppl 5

    Topics: Animals; Arthritis; Autoimmune Diseases; Autoimmunity; Disease Models, Animal; Humans; Inflammation;

1998
Nitric oxide and peroxynitrite production in ocular inflammation.
    Environmental health perspectives, 1998, Volume: 106 Suppl 5

    Topics: Animals; Disease Models, Animal; Eye; Humans; Inflammation Mediators; Mice; Nitrates; Nitric Oxide;

1998
Oxidative stress and vascular damage in hypertension.
    Current opinion in nephrology and hypertension, 2001, Volume: 10, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Vessels; Cardiovascular Diseases; Diseas

2001

Trials

5 trials available for nitrates and Disease Models, Animal

ArticleYear
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
    Medicina clinica (English ed.), 2022, Dec-23, Volume: 159, Issue:12

    Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter

2022
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
An engineered
    Science translational medicine, 2019, 01-16, Volume: 11, Issue:475

    Topics: Ammonia; Animals; Arginine; Biosynthetic Pathways; Disease Models, Animal; Escherichia coli; Feces;

2019
    Obesity science & practice, 2016, Volume: 2, Issue:1

    Topics: Absorptiometry, Photon; Adult; Air Pollutants; Alkynes; Alleles; Animals; Anthracenes; Anthraquinone

2016
N(G)-monomethyl-L-arginine improves survival in a pig model of abdominal sepsis.
    Critical care medicine, 1998, Volume: 26, Issue:9

    Topics: Animals; Bacteremia; Critical Care; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Nitrate

1998

Other Studies

458 other studies available for nitrates and Disease Models, Animal

ArticleYear
Effect of Agmatine on a mouse model of allergic airway inflammation: A comparative study.
    Autoimmunity, 2022, Volume: 55, Issue:8

    Topics: Agmatine; Animals; Anti-Asthmatic Agents; Beclomethasone; Cytokines; Disease Models, Animal; Inflamm

2022
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 154

    Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Drugs, Chines

2022
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis
    Antioxidants & redox signaling, 2023, Volume: 38, Issue:10-12

    Topics: Animals; Chemokine CXCL12; Collagen Type I; Cyclic AMP Receptor Protein; Disease Models, Animal; Fib

2023
Dietary nitrate improves jaw bone remodelling in zoledronate-treated mice.
    Cell proliferation, 2023, Volume: 56, Issue:7

    Topics: Animals; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone

2023
Nicorandil Exerts Anticonvulsant Effects in Pentylenetetrazol-Induced Seizures and Maximal-Electroshock-Induced Seizures by Downregulating Excitability in Hippocampal Pyramidal Neurons.
    Neurochemical research, 2023, Volume: 48, Issue:9

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Hippocampus;

2023
Evaluation of a rat model of functional urinary bladder outlet obstruction produced by chronic inhibition of nitric oxide synthase.
    Life sciences, 2019, Oct-01, Volume: 234

    Topics: Animals; Disease Models, Animal; Female; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synth

2019
Effects of inorganic nitrate in a rat model of monocrotaline-induced pulmonary arterial hypertension.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 126, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Lung; Male; Monocro

2020
Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring.
    PloS one, 2019, Volume: 14, Issue:9

    Topics: Animals; Disease Models, Animal; Female; Fibrosis; Kidney; Kidney Tubular Necrosis, Acute; Male; Mal

2019
Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status.
    Redox biology, 2020, Volume: 28

    Topics: Adipocytes; Animals; Blood Glucose; Cell Respiration; Diet, High-Fat; Disease Models, Animal; Gene E

2020
Effects of nitric oxide donor on the lung functions in a saline lavage-induced model of ARDS.
    Physiological research, 2019, 12-20, Volume: 68, Issue:Suppl 3

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Lung; Male; Nitrates; Nitric

2019
Head-to-head comparison of inorganic nitrate and metformin in a mouse model of cardiometabolic disease.
    Nitric oxide : biology and chemistry, 2020, 04-01, Volume: 97

    Topics: Administration, Oral; Animals; Cardiovascular Diseases; Diet, High-Fat; Disease Models, Animal; Enzy

2020
Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide.
    Molecular and cellular biochemistry, 2020, Volume: 468, Issue:1-2

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dyslipidemias; Heart; Insulin Resistance; Male;

2020
Consistent gastric pH-dependent effects of suppressors of gastric acid secretion on the antihypertensive responses to oral nitrite.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Gast

2020
Synergistic Effects of Moderate Therapeutic Hypothermia and Levosimendan on Cardiac Function and Survival After Asphyxia-Induced Cardiac Arrest in Rats.
    Journal of the American Heart Association, 2020, 06-16, Volume: 9, Issue:12

    Topics: Animals; Asphyxia; Biomarkers; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy; Diseas

2020
Intra-Articular Route for the System of Molecules 14G1862 from
    Nutrients, 2020, May-31, Volume: 12, Issue:6

    Topics: Analgesics; Animals; Arthritis, Experimental; Cell Survival; Centella; Disease Models, Animal; Hyper

2020
Protective effect of dietary nitrate on stress-induced gastric mucosal injury via enhancing blood perfusion in Mongolian gerbils.
    Chinese medical journal, 2020, Sep-05, Volume: 133, Issue:17

    Topics: Animals; Disease Models, Animal; Gastric Mucosa; Gerbillinae; Helicobacter Infections; Helicobacter

2020
Sodium nitrate co-supplementation does not exacerbate low dose metronomic doxorubicin-induced cachexia in healthy mice.
    Scientific reports, 2020, 09-24, Volume: 10, Issue:1

    Topics: Administration, Metronomic; Animals; Antibiotics, Antineoplastic; Body Composition; Cachexia; Calori

2020
Electrochemical evidence of nitrate release from the nitrooxy compound 4-((nitrooxy) methyl)-3-nitrobenzoic acid and its antinociceptive and anti-inflammatory activities in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Elect

2021
Site-specific identification and validation of hepatic histone nitration in vivo: Implications for alcohol-induced liver injury.
    Journal of mass spectrometry : JMS, 2021, Volume: 56, Issue:6

    Topics: Amino Acid Sequence; Animals; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Anima

2021
Sex-Dependent Effects of Nephron Ift88 Disruption on BP, Renal Function, and Cystogenesis.
    Journal of the American Society of Nephrology : JASN, 2021, Volume: 32, Issue:9

    Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Male; Mice; Mice, Knockout; Natriuresis; Ne

2021
The Roles of Dominance of the Nitric Oxide Fractions Nitrate and Nitrite in the Epilepsy-Prone EL Mouse Brain.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2021, Volume: 88, Issue:3

    Topics: Animals; Disease Models, Animal; Epilepsy; Hippocampus; Mice, Inbred Strains; Nerve Net; Nitrates; N

2021
Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery.
    Nature communications, 2021, 07-23, Volume: 12, Issue:1

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Drug Implants; Heart; Macrophage Activation; Ma

2021
Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide.
    British journal of pharmacology, 2022, Volume: 179, Issue:20

    Topics: Animals; Cardiomegaly; Case-Control Studies; Clinical Studies as Topic; Disease Models, Animal; Fibr

2022
CXCR4 signaling in macrophages contributes to periodontal mechanical hypersensitivity in Porphyromonas gingivalis-induced periodontitis in mice.
    Molecular pain, 2017, Volume: 13

    Topics: Animals; Antibodies; Antigens, Differentiation; Bacteroidaceae Infections; Disease Models, Animal; H

2017
Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis.
    Inflammopharmacology, 2018, Volume: 26, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis; Colon; Disease Models, Animal; I

2018
Fullerenol nanoparticles decrease ischaemia-induced brain injury and oedema through inhibition of oxidative damage and aquaporin-1 expression in ischaemic stroke.
    Brain injury, 2017, Volume: 31, Issue:8

    Topics: Animals; Aquaporin 1; Brain Edema; Brain Infarction; Brain Injuries; Cerebrovascular Circulation; Di

2017
Identification and quantification of protein
    The Journal of biological chemistry, 2017, 09-01, Volume: 292, Issue:35

    Topics: Affinity Labels; Animals; Cardiotonic Agents; Cell Membrane Permeability; Cysteine; Disease Models,

2017
Effects of supplementation with spray-dried porcine plasma on blood variables on piglets feed with diet contaminated by mycotoxins.
    Microbial pathogenesis, 2017, Volume: 110

    Topics: Aflatoxins; Animals; Blood Chemical Analysis; Body Weight; C-Reactive Protein; Dietary Supplements;

2017
Corneal angiogenesis based on different protocols of alkaline cauterization in murine models.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:8

    Topics: Animals; Cautery; Cornea; Corneal Neovascularization; Disease Models, Animal; Male; Neovascularizati

2017
Metformin influences on respiratory system in obese mice induced by postnatal overnutrition.
    Respiratory physiology & neurobiology, 2018, Volume: 247

    Topics: Animals; Bronchoalveolar Lavage Fluid; Diet; Disease Models, Animal; Hypoglycemic Agents; Lung; Male

2018
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:2

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alph

2018
Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Mar-15, Volume: 51, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cannabidiol; Disease Models, Animal; Enteritis; Female; Fetal Dis

2018
Chronic Intermittent Hypobaric Hypoxia (4600 M) Attenuates Pulmonary Vasodilation Induced by Acetylcholine or Sodium Nitroprusside.
    High altitude medicine & biology, 2018, Volume: 19, Issue:2

    Topics: Acetylcholine; Altitude; Altitude Sickness; Animals; Blood Pressure; Body Weight; Chronic Disease; D

2018
Inhibition of Fatty Acid Amide Hydrolase by PF-3845 Alleviates the Nitrergic and Proinflammatory Response in Rat Hippocampus Following Acute Stress.
    The international journal of neuropsychopharmacology, 2018, 08-01, Volume: 21, Issue:8

    Topics: Amidohydrolases; Animals; Corticosterone; Cytokines; Disease Models, Animal; Endocannabinoids; Enzym

2018
Effect of pioglitazone and simvastatin in lipopolysaccharide-induced amyloidogenesis and cognitive impairment in mice: possible role of glutamatergic pathway and oxidative stress.
    Behavioural pharmacology, 2019, Volume: 30, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Dose

2019
Dimethyl Fumarate Limits Neuroinflammation and Oxidative Stress and Improves Cognitive Impairment After Polymicrobial Sepsis.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Animals; Catalase; Cognition Disorders; Cytokines; Dimethyl Fumarate; Disease Models, Animal; Explor

2018
Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome.
    Investigative ophthalmology & visual science, 2018, 06-01, Volume: 59, Issue:7

    Topics: Administration, Ophthalmic; Animals; Conjunctiva; Disease Models, Animal; Dry Eye Syndromes; Goblet

2018
Anaerobic nitrate reduction divergently governs population expansion of the enteropathogen Vibrio cholerae.
    Nature microbiology, 2018, Volume: 3, Issue:12

    Topics: Anaerobiosis; Animals; Bacteria; Cholera; Disease Models, Animal; Fermentation; Hydrogen-Ion Concent

2018
Comparison of the Effects of Subconjunctival Injections of Bevacizumab and Interferon Alpha-2a on Corneal Angiogenesis in a Rat Model.
    Medicina (Kaunas, Lithuania), 2018, Apr-16, Volume: 54, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Conjunctiva; Corneal Neovascularization; Disease Mode

2018
Dietary Nitrite Attenuates Elastase-Induced Pulmonary Emphysema in a Mouse Model.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:12

    Topics: Animals; Diet; Disease Models, Animal; Female; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitrites;

2018
Protective Effect of TLR4 Ablation against Corneal Neovascularization following Chemical Burn in a Mouse Model.
    Current eye research, 2019, Volume: 44, Issue:5

    Topics: Animals; Burns, Chemical; Cornea; Corneal Neovascularization; Disease Models, Animal; Drug Combinati

2019
Effects of phosphodiesterase 5 inhibitor sildenafil on the respiratory parameters, inflammation and apoptosis in a saline lavage-induced model of acute lung injury.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018, Volume: 69, Issue:5

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Bronchoalveolar Lavage; Cytokines;

2018
Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II-Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:4

    Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Dietary Supplements; Disease Models, Animal; Hy

2019
Nitrergic signaling modulation by ascorbic acid treatment is responsible for anxiolysis in mouse model of anxiety.
    Behavioural brain research, 2019, 05-17, Volume: 364

    Topics: Affect; Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Ascorbic Acid; Behavior, Animal; B

2019
Small Amounts of Inorganic Nitrate or Beetroot Provide Substantial Protection From Salt-Induced Increases in Blood Pressure.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:5

    Topics: Animals; Beta vulgaris; Blood Pressure; Diet; Disease Models, Animal; Hypertension; Male; Nitrates;

2019
The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models.
    British journal of pharmacology, 2019, Volume: 176, Issue:17

    Topics: Animals; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Hum

2019
Pneumonia-induced sepsis in mice: temporal study of inflammatory and cardiovascular parameters.
    International journal of experimental pathology, 2013, Volume: 94, Issue:2

    Topics: Animals; Bacterial Load; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Humans; Kl

2013
Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Animals; Asthma; Disease Models, Animal; Eflornithine; Female; Humans; Hypersensi

2013
[Combined effects of aluminium and immobilization stress on the reproductive system of male rats].
    Meditsina truda i promyshlennaia ekologiia, 2012, Issue:11

    Topics: Aluminum Compounds; Animals; Disease Models, Animal; Female; Injections, Intraperitoneal; Male; Nitr

2012
Cleaved caspase-3 expression in hypothalamic magnocellular neurons may affect vasopressin secretion during experimental polymicrobial sepsis.
    Journal of neuroimmunology, 2013, May-15, Volume: 258, Issue:1-2

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cytokines; Disease Models, Animal; Enzyme-Linked I

2013
Activation of cGMP/protein kinase G pathway in postconditioned myocardium depends on reduced oxidative stress and preserved endothelial nitric oxide synthase coupling.
    Journal of the American Heart Association, 2013, Jan-02, Volume: 2, Issue:1

    Topics: Animals; Biopterins; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, A

2013
Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock.
    BMC immunology, 2013, Apr-02, Volume: 14

    Topics: Animals; Biomarkers; Disease Models, Animal; Humans; Inflammation; Interleukin-10; Interleukin-6; Li

2013
Evaluation of the Hepa Wash® treatment in pigs with acute liver failure.
    BMC gastroenterology, 2013, May-13, Volume: 13

    Topics: Ammonia; Animals; Blood Pressure; Cardiac Output; Creatinine; Dialysis; Disease Models, Animal; Fema

2013
The effect of calorie restriction on acute ethanol-induced oxidative and nitrosative liver injury in rats.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2

    Topics: Acute Disease; Animals; Caloric Restriction; Disease Models, Animal; Ethanol; Glutathione; Liver; Li

2013
Caloric restriction reduces edema and prolongs survival in a mouse glioma model.
    Journal of neuro-oncology, 2013, Volume: 114, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Brain Edema; Brain Neoplasms; Caloric Restriction; Cell Line, Tumor;

2013
Croton antisyphiliticus Mart. attenuates the inflammatory response to carrageenan-induced pleurisy in mice.
    Inflammopharmacology, 2014, Volume: 22, Issue:2

    Topics: Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Carrageenan; Croton; Disease Models, Animal;

2014
Dynamics of oxidative/nitrosative stress in mice with methionine-choline-deficient diet-induced nonalcoholic fatty liver disease.
    Human & experimental toxicology, 2014, Volume: 33, Issue:7

    Topics: Animals; Antioxidants; C-Reactive Protein; Catalase; Choline Deficiency; Disease Models, Animal; Fer

2014
Glucocorticoids downregulate systemic nitric oxide synthesis and counteract overexpression of hepatic heme oxygenase-1 during endotoxin tolerance.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:10

    Topics: Adrenalectomy; Animals; Corticosterone; Dexamethasone; Disease Models, Animal; Down-Regulation; Endo

2013
Interactive effects of mechanical ventilation, inhaled nitric oxide and oxidative stress in acute lung injury.
    Respiratory physiology & neurobiology, 2014, Jan-01, Volume: 190

    Topics: Acute Lung Injury; Administration, Inhalation; Animals; Bronchodilator Agents; Cell Count; Disease M

2014
Aldehyde dehydrogenase 2 partly mediates hypotensive effect of nitrite on L-NAME-induced hypertension in normoxic rat.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:6

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antihypertensive Agents; Blo

2014
Systemic administration of Rosmarinus officinalis attenuates the inflammatory response induced by carrageenan in the mouse model of pleurisy.
    Planta medica, 2013, Volume: 79, Issue:17

    Topics: Abietanes; Adenosine Deaminase; Animals; Anti-Inflammatory Agents; Carrageenan; Cinnamates; Cytokine

2013
Alpha-lipoic acid restores tear production in an animal model of dry eye.
    Experimental eye research, 2014, Volume: 120

    Topics: Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Conjunctiva; Cornea; Die

2014
Preventive and therapeutic effects of nitrite supplementation in experimental inflammatory bowel disease.
    Redox biology, 2014, Volume: 2

    Topics: Animals; Cell Line; Colitis; Colon; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Dr

2014
Agmatine attenuates silica-induced pulmonary fibrosis.
    Human & experimental toxicology, 2014, Volume: 33, Issue:6

    Topics: Agmatine; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cytoprotection; Disease Models, Animal;

2014
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jun-03, Volume: 111, Issue:22

    Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cellulase; Diet, Mediterranean; Disease Model

2014
Silymarin ameliorates memory deficits and neuropathological changes in mouse model of high-fat-diet-induced experimental dementia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:8

    Topics: Acetylcholinesterase; Animals; Body Weight; Brain; Cholesterol; Dementia; Diet, High-Fat; Disease Mo

2014
Increased aortic stiffness elevates pulse and mean pressure and compromises endothelial function in Wistar rats.
    American journal of physiology. Heart and circulatory physiology, 2014, Sep-15, Volume: 307, Issue:6

    Topics: Animals; Aorta; Arterial Pressure; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dose-Resp

2014
Conventional, but not remote ischemic preconditioning, reduces iNOS transcription in liver ischemia/reperfusion.
    World journal of gastroenterology, 2014, Jul-28, Volume: 20, Issue:28

    Topics: Animals; Disease Models, Animal; Down-Regulation; Hindlimb; Inflammation Mediators; Ischemic Precond

2014
The effect of melatonin on procarbazine induced testicular toxicity on rats.
    Systems biology in reproductive medicine, 2014, Volume: 60, Issue:6

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cytoprotection; Disease Models, Animal; Follicle Stimu

2014
NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:1

    Topics: Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Mice; Mice, Inbred C57B

2015
Relationship between oxidative stress and pathological findings in abomasum of infected lambs by Haemonchus contortus.
    Pathology, research and practice, 2014, Volume: 210, Issue:12

    Topics: Abomasum; Advanced Oxidation Protein Products; Animals; Animals, Newborn; Antioxidants; Biomarkers;

2014
Dietary nitrate improves glucose tolerance and lipid profile in an animal model of hyperglycemia.
    Nitric oxide : biology and chemistry, 2015, Jan-30, Volume: 44

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyperg

2015
Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen.
    Life sciences, 2015, Apr-01, Volume: 126

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Drug Evaluat

2015
Protective effect of leaf essential oil from Cinnamomum osmophloeum Kanehira on endotoxin-induced intestinal injury in mice associated with suppressed local expression of molecules in the signaling pathways of TLR4 and NLRP3.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Carrier Proteins; Cinnamomum; Cytokines; Disease Mod

2015
Protective and immunomodulatory effect of flos Lonicerae japonicae by augmenting IL-10 expression in a murine model of acute lung inflammation.
    Journal of ethnopharmacology, 2015, Jun-20, Volume: 168

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cell Count; Cyto

2015
Therapeutic potential of ixmyelocel-T, an expanded autologous multicellular therapy for treatment of ischemic cardiovascular diseases.
    Stem cell research & therapy, 2015, Mar-13, Volume: 6

    Topics: Animals; Apoptosis; Becaplermin; Bone Marrow Cells; Bone Marrow Transplantation; Cell Proliferation;

2015
Thalidomide ameliorates portal hypertension via nitric oxide synthase independent reduced systolic blood pressure.
    World journal of gastroenterology, 2015, Apr-14, Volume: 21, Issue:14

    Topics: Animals; Antihypertensive Agents; Aorta, Abdominal; Arterial Pressure; Biomarkers; Blood Flow Veloci

2015
Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved?
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Administration, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models,

2015
Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome.
    American journal of physiology. Heart and circulatory physiology, 2015, Jul-01, Volume: 309, Issue:1

    Topics: Angiogenesis Inducing Agents; Animals; Delayed-Action Preparations; Disease Models, Animal; Hindlimb

2015
Neuroprotective effect of Allium cepa L. in aluminium chloride induced neurotoxicity.
    Neurotoxicology, 2015, Volume: 49

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Avoidance Learning; Brain; Cat

2015
Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion.
    European journal of pharmacology, 2015, Sep-05, Volume: 762

    Topics: Active Transport, Cell Nucleus; Amides; Animals; Apoptosis; Cell Nucleus; Chymases; Cytokines; Disea

2015
Impairment of skin barrier function via cholinergic signal transduction in a dextran sulphate sodium-induced colitis mouse model.
    Experimental dermatology, 2015, Volume: 24, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Atropine; Cell Count; Colitis; Colon; Dextran Sulfate; Disease Mode

2015
Rimonabant Improves Oxidative/Nitrosative Stress in Mice with Nonalcoholic Fatty Liver Disease.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Animals; Cannabinoid Receptor Antagonists; Diet, High-Fat; Disease Models, Animal; Glutathione; Live

2015
Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.
    Clinical and experimental pharmacology & physiology, 2015, Volume: 42, Issue:11

    Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Collagen; Disease Models, Anima

2015
Histological characteristics following a long-term nitrate-rich diet in miniature pigs with parotid atrophy.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:6

    Topics: Animals; Apoptosis; Atrophy; Chromatography, High Pressure Liquid; Dietary Supplements; Disease Mode

2015
Curcumin, Hesperidin, and Rutin Selectively Interfere with Apoptosis Signaling and Attenuate Streptozotocin-Induced Oxidative Stress-Mediated Hyperglycemia.
    Current neurovascular research, 2015, Volume: 12, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood Glucose; Cu

2015
Chronic liver injury in mice promotes impairment of skin barrier function via tumor necrosis factor-alpha.
    Cutaneous and ocular toxicology, 2016, Volume: 35, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

2016
Role of thioredoxin nitration in bleomycin-induced pulmonary fibrosis in rats.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:1

    Topics: Animals; Bleomycin; Disease Models, Animal; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; L

2016
An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Blotting, Western; Brain; Cytosol; Disease Models, Animal; Fragile X Mental Retardation Pro

2016
A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics.
    Scientific reports, 2016, Feb-03, Volume: 6

    Topics: Animals; Anti-Inflammatory Agents; Bacterial Proteins; Cell Survival; Cells, Cultured; Cytokines; De

2016
Distant effects of unilateral renal ischemia/reperfusion on contralateral kidney but not lung in rats: the roles of ROS and iNOS.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:5

    Topics: Acute Kidney Injury; alpha-Tocopherol; Animals; Antioxidants; Disease Models, Animal; Enzyme Inhibit

2016
Selective Serotonin-norepinephrine Re-uptake Inhibition Limits Renovas-cular-hypertension Induced Cognitive Impairment, Endothelial Dysfunction, and Oxidative Stress Injury.
    Current neurovascular research, 2016, Volume: 13, Issue:2

    Topics: Acetylcholinesterase; Animals; Arterial Pressure; Cognition Disorders; Disease Models, Animal; Dose-

2016
[Tumor necrosis factor-α inhibitor protects against myocardial ischemia/reperfusion injury via Notch1 mediated inhibition of oxidative/nitrative stress in traumatic mice].
    Zhonghua xin xue guan bing za zhi, 2016, Volume: 44, Issue:2

    Topics: Animals; Caspase 3; Disease Models, Animal; Down-Regulation; Mice; Myocardial Reperfusion Injury; My

2016
Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite.
    Journal of visualized experiments : JoVE, 2016, Feb-16, Issue:108

    Topics: Animals; Disease Models, Animal; Embryo, Nonmammalian; Embryonic Development; Female; Male; Models,

2016
Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney.
    Scientific reports, 2016, 05-26, Volume: 6

    Topics: Animals; Disease Models, Animal; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertens

2016
Effect of ruthenium red, a ryanodine receptor antagonist in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats.
    Physiology & behavior, 2016, 10-01, Volume: 164, Issue:Pt A

    Topics: Animals; Aorta; Blood Glucose; Body Weight; Brain; Calcium Channel Blockers; Dementia; Diabetes Mell

2016
Energy Taxis toward Host-Derived Nitrate Supports a Salmonella Pathogenicity Island 1-Independent Mechanism of Invasion.
    mBio, 2016, 07-19, Volume: 7, Issue:4

    Topics: Animals; Bacterial Proteins; Cecum; Chemotaxis; Disease Models, Animal; Endocytosis; Energy Metaboli

2016
In situ eNOS/NO up-regulation-a simple and effective therapeutic strategy for diabetic skin ulcer.
    Scientific reports, 2016, 07-25, Volume: 6

    Topics: Animals; Blood Glucose; Cell Survival; Diabetes Complications; Diabetes Mellitus, Type 1; Disease Mo

2016
Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mouthw

2016
Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Blood Glucose; Blood Volume; Cecum; Curcumin; Cytokin

2017
Nilotinib, a tyrosine kinase inhibitor exhibits protection against acute pancreatitis-induced lung and liver damage in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:3

    Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Biomarkers; Cyto

2017
Inhibition of matrix metalloproteinase-9 by a barbiturate-nitrate hybrid ameliorates dextran sulphate sodium-induced colitis: effect on inflammation-related genes.
    British journal of pharmacology, 2017, Volume: 174, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Colitis; Dextran Sulfate; Disease Mo

2017
Increasing dietary nitrate has no effect on cancellous bone loss or fecal microbiome in ovariectomized rats.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:5

    Topics: Absorptiometry, Photon; Alcaligenaceae; Animals; Bacteroidaceae; Biomarkers; Bone Density; Bone Reso

2017
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis.
    Nature chemical biology, 2008, Volume: 4, Issue:7

    Topics: Adult; Allopurinol; Animals; Blood Pressure; Disease Models, Animal; Female; Homeostasis; Humans; Li

2008
Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model.
    Acta cirurgica brasileira, 2008, Volume: 23 Suppl 1

    Topics: Acute Disease; Animals; Biomarkers; Cholagogues and Choleretics; Disease Models, Animal; Drug Evalua

2008
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.
    Behavioural brain research, 2008, Nov-21, Volume: 193, Issue:2

    Topics: Animals; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Curcumin; Disea

2008
Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:4

    Topics: Amidines; Animals; Benzylamines; Blood Pressure; Chemokines; Cytokines; Disease Models, Animal; Enzy

2008
Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: a role for oxidative stress.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:5

    Topics: Acetylcholine; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Female; HSP90 Heat-

2008
L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia.
    Iranian biomedical journal, 2008, Volume: 12, Issue:3

    Topics: Animals; Arginine; Cholesterol; Dietary Supplements; Disease Models, Animal; Hypercholesterolemia; M

2008
Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Sep-15, Volume: 181, Issue:6

    Topics: Animals; Arginase; Boronic Acids; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enz

2008
Hyperthermia amplifies brain cytokine and reactive oxygen species response in a model of perinatal inflammation.
    Neuroscience letters, 2008, Nov-21, Volume: 445, Issue:3

    Topics: Animals; Brain; Cytokines; Disease Models, Animal; Female; Hyperthermia, Induced; Hypoxia; Inflammat

2008
Endothelin and gelatinases in renal changes following blockade of nitric oxide synthase in hypertensive rats.
    The Chinese journal of physiology, 2008, Jun-30, Volume: 51, Issue:3

    Topics: Animals; Azepines; Blood Urea Nitrogen; Collagen; Creatinine; Cyclic GMP; Disease Models, Animal; En

2008
Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model.
    Alcoholism, clinical and experimental research, 2010, Volume: 34 Suppl 1

    Topics: Amino Acids; Animals; Blotting, Western; Choline; Choline Deficiency; Diet; Disease Models, Animal;

2010
Deletion of inducible nitric oxide synthase provides cardioprotection in mice with 2-kidney, 1-clip hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:1

    Topics: Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Gene Deletion; Hypertension, Renovascular

2009
Role of neuronal nitric oxide synthase in ovine sepsis model.
    Shock (Augusta, Ga.), 2009, Volume: 32, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Hemodynamics; Interleukin-6; Lung; Lung Injury; Nitrates; N

2009
Naltrexone protects against lipopolysaccharide/D-galactosamine-induced hepatitis in mice.
    Journal of pharmacological sciences, 2008, Volume: 108, Issue:3

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Inju

2008
Chronic hypoxia increases inducible NOS-derived nitric oxide in fetal guinea pig hearts.
    Pediatric research, 2009, Volume: 65, Issue:2

    Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factor

2009
The levels of glutathione and nitrite-nitrate and the expression of Bcl-2 mRNA in ovariectomized rats treated by raloxifene against kainic acid.
    The International journal of neuroscience, 2009, Volume: 119, Issue:2

    Topics: Animals; Apoptosis; Disease Models, Animal; Female; Glutathione; Kainic Acid; Nerve Degeneration; Ne

2009
Prenatal lipopolysaccharide increases postnatal intestinal injury in a rat model of necrotizing enterocolitis.
    Journal of pediatric gastroenterology and nutrition, 2009, Volume: 48, Issue:3

    Topics: Animals; Animals, Newborn; Blood Pressure; Disease Models, Animal; Enterocolitis, Necrotizing; Enzym

2009
Antiinflammatory and antihyperalgesic activity of C-phycocyanin.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Dinoprostone; Disease

2009
Effects of 2,3,4',5-tetrahydroxystilbene 2-O-beta-D-glucoside on vascular endothelial dysfunction in atherogenic-diet rats.
    Planta medica, 2009, Volume: 75, Issue:11

    Topics: Animals; Aorta; Atherosclerosis; Disease Models, Animal; Drugs, Chinese Herbal; Endothelium, Vascula

2009
Suppression of diet-induced hypercholesterolemia by scutellarin in rats.
    Planta medica, 2009, Volume: 75, Issue:11

    Topics: Animals; Anticholesteremic Agents; Apigenin; Cholesterol; Disease Models, Animal; Drugs, Chinese Her

2009
Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy.
    Journal of neuroscience research, 2009, Volume: 87, Issue:12

    Topics: alpha-Synuclein; Animals; Brain; Convulsants; Disease Models, Animal; Mice; Mice, Transgenic; Mitoch

2009
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
    Experimental neurology, 2009, Volume: 217, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Lin

2009
Hyperglycemia contributes to cardiac dysfunction in a lipopolysaccharide-induced systemic inflammation model.
    Critical care medicine, 2009, Volume: 37, Issue:7

    Topics: Animals; Cytokines; Disease Models, Animal; HMGB1 Protein; Hyperglycemia; Hypoglycemic Agents; Insul

2009
Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Angiotensin II; Animals; Bilirubin; Blood Pressure; Cardiomegaly; Disease Models, Animal; Glucuronos

2009
Lonomia obliqua caterpillar envenomation causes platelet hypoaggregation and blood incoagulability in rats.
    Toxicon : official journal of the International Society on Toxinology, 2010, Volume: 55, Issue:1

    Topics: Animals; Arthropod Venoms; Blood Coagulation; Brazil; Disease Models, Animal; Fibrinogen; Hemorrhage

2010
Antinociceptive effects of NCX-701 (nitro-paracetamol) in neuropathic rats: enhancement of antinociception by co-administration with gabapentin.
    British journal of pharmacology, 2009, Volume: 158, Issue:2

    Topics: Acetaminophen; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dos

2009
Hypercholesterolemia impairs exercise capacity in mice.
    Vascular medicine (London, England), 2009, Volume: 14, Issue:3

    Topics: Aging; Animals; Aorta; Apolipoproteins E; Cholesterol, Dietary; Citrate (si)-Synthase; Disease Model

2009
Role of macrophages in the development of pancreatic islet injury in spontaneously diabetic torii rats.
    Experimental animals, 2009, Volume: 58, Issue:4

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bone Density Conservation Agents;

2009
Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia.
    World journal of pediatrics : WJP, 2009, Volume: 5, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Catalase; Disease Models, Animal; Glutathione Peroxidase; H

2009
Medical ozone therapy reduces oxidative stress and intestinal damage in an experimental model of necrotizing enterocolitis in neonatal rats.
    Journal of pediatric surgery, 2009, Volume: 44, Issue:9

    Topics: Animals; Animals, Newborn; Biomarkers; Disease Models, Animal; Enterocolitis, Necrotizing; Glutathio

2009
Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Creatine Kinase; Disease Models, Animal; Female; Glutathione;

2009
Cocaine-induced status epilepticus and death generate oxidative stress in prefrontal cortex and striatum of mice.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: Animals; Antioxidants; Biomarkers; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Death, Sudde

2010
Renal NOS activity, expression, and localization in male and female spontaneously hypertensive rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:1

    Topics: Animals; Cyclic GMP; Disease Models, Animal; Female; Hypertension; Kidney Cortex; Kidney Medulla; Ma

2010
Effect of astaxanthin on hepatocellular injury following ischemia/reperfusion.
    Toxicology, 2010, Jan-12, Volume: 267, Issue:1-3

    Topics: Alanine Transaminase; Animals; Antioxidants; Disease Models, Animal; Glutathione; Liver; Male; Nitra

2010
Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis.
    Glia, 2010, Volume: 58, Issue:5

    Topics: Animals; Antigens, CD; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Central Nervous Syste

2010
Lung, liver and bone cancer mortality after plutonium exposure in beagle dogs and nuclear workers.
    Health physics, 2010, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Air Pollutants, Radioactive; Animals; Bone Neoplasms; Cohort Studies; Disea

2010
Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum.
    Journal of neurochemistry, 2010, Volume: 112, Issue:4

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models,

2010
On the dynamics of nitrite, nitrate and other biomarkers of nitric oxide production in inflammatory bowel disease.
    Nitric oxide : biology and chemistry, 2010, Feb-15, Volume: 22, Issue:2

    Topics: Animals; Biomarkers; Disease Models, Animal; Inflammatory Bowel Diseases; Male; Mesalamine; Nitrates

2010
Nitroglycerin-induced preconditioning: interaction with nitrate tolerance.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

2010
Development of animal model for vasculatic neuropathy: Induction by ischemic-reperfusion in the rat femoral artery.
    Journal of neuroscience methods, 2010, Feb-15, Volume: 186, Issue:2

    Topics: Animals; Disease Models, Animal; Femoral Artery; Foot; Hot Temperature; Interleukin-10; Malondialdeh

2010
An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.
    PloS one, 2009, Dec-22, Volume: 4, Issue:12

    Topics: Animals; Disease Models, Animal; Female; Humans; Inflammation; Male; Middle Aged; Nitrates; Nitrites

2009
Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Bifla

2010
Phenolic extract of soybean (Glycine max) attenuates cisplatin-induced nephrotoxicity in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:4

    Topics: 5'-Nucleotidase; Acetylglucosaminidase; Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxi

2010
Myeloperoxidase increased cardiomyocyte protein nitration in mice subjected to nonlethal mechanical trauma.
    Biochemical and biophysical research communications, 2010, Mar-12, Volume: 393, Issue:3

    Topics: Animals; Apoptosis; Cell Adhesion; Disease Models, Animal; Heart Injuries; Male; Mice; Mice, Inbred

2010
Gastroprotective effect of Saccharomyces boulardii in a rat model of ibuprofen-induced gastric ulcer.
    Pharmacology, 2010, Volume: 85, Issue:3

    Topics: Animals; Body Weight; Cytoprotection; Disease Models, Animal; Gastric Mucosa; Ibuprofen; Male; Nitra

2010
Cepharanthine exerts anti-inflammatory effects via NF-κB inhibition in a LPS-induced rat model of systemic inflammation.
    The Journal of surgical research, 2011, Volume: 171, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Cell Line; Disease Models, An

2011
Oral nitrite ameliorates dextran sulfate sodium-induced acute experimental colitis in mice.
    Nitric oxide : biology and chemistry, 2010, Aug-01, Volume: 23, Issue:1

    Topics: Analysis of Variance; Animals; Blood Pressure; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease

2010
Increased inducible nitric oxide synthase and arginase II expression in heart failure: no net nitrite/nitrate production and protein S-nitrosylation.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:2

    Topics: Animals; Arginase; Arginine; Blotting, Western; Cardiac Pacing, Artificial; Disease Models, Animal;

2010
Beneficial effects of magnolol in a rodent model of endotoxin shock.
    European journal of pharmacology, 2010, Sep-01, Volume: 641, Issue:1

    Topics: Animals; Antithrombin III; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Gene Expressi

2010
Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction.
    Respiratory research, 2010, Jun-21, Volume: 11

    Topics: Acute Disease; Administration, Inhalation; Animals; Blood Pressure; Cardiac Output; Chemistry, Pharm

2010
The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock.
    Shock (Augusta, Ga.), 2011, Volume: 35, Issue:2

    Topics: Acute Lung Injury; Animals; Catalysis; Disease Models, Animal; Female; Lung; Malondialdehyde; Nitrat

2011
Involvement of nitric oxide in a rat model of carrageenin-induced pleurisy.
    Mediators of inflammation, 2010, Volume: 2010

    Topics: Animals; Antioxidants; Arginine; Carrageenan; Disease Models, Animal; Male; Malondialdehyde; Nitrate

2010
Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model.
    Critical care (London, England), 2010, Volume: 14, Issue:4

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Interleukin-8; Lung; Nitrates; Nitric Oxide Synt

2010
Nitric oxide pros and cons: The role of L-arginine, a nitric oxide precursor, and idebenone, a coenzyme-Q analogue in ameliorating cerebral hypoxia in rat.
    Brain research bulletin, 2010, Aug-30, Volume: 83, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Arginine; Brain; Catalase; Creatine Kinase; Disease M

2010
ETS-GS, a new anti-oxidative drug, protects against lipopolysaccharide-induced acute lung and liver injury.
    The Journal of surgical research, 2011, Volume: 171, Issue:2

    Topics: Acute Lung Injury; Animals; Antioxidants; Cell Line; Chemical and Drug Induced Liver Injury; Disease

2011
Insulin treatment of diabetic rats reduces cardiac function in a lipopolysaccharide-induced systemic inflammation model.
    The Journal of surgical research, 2011, Volume: 171, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Heart Diseases; Hea

2011
Simvastatin effects on portal-systemic collaterals of portal hypertensive rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:8

    Topics: Animals; Arginine Vasopressin; Collateral Circulation; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost

2010
Indomethacin activates peroxisome proliferator-activated receptor γ to improve insulin resistance in cotton pellet granuloma model.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:11

    Topics: Adipose Tissue; Animals; Cell Movement; Cotton Fiber; Cyclooxygenase 2; Dinoprostone; Disease Models

2010
Danaparoid sodium attenuates the effects of heat stress.
    The Journal of surgical research, 2011, Volume: 171, Issue:2

    Topics: Acute Disease; Animals; Anticoagulants; Antithrombin III; Chondroitin Sulfates; Cytokines; Dermatan

2011
Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:4

    Topics: Animals; Antioxidants; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Magnetic Resonance

2010
Synthesis and pharmacological evaluation of novel 1-(2-(benzoyl-substituted-2-phenyl-1H-indol-5-carbony) hydrazinyloxy) vinyl nitrate derivatives as potent non-ulcerogenic, analgesic and anti-inflammatory agents.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2010, Volume: 6, Issue:4

    Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dis

2010
Role of mouse cerebellar nicotinic acetylcholine receptor (nAChR) α(4)β(2)- and α(7) subtypes in the behavioral cross-tolerance between nicotine and ethanol-induced ataxia.
    Behavioural brain research, 2011, Mar-01, Volume: 217, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Comp

2011
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
    Translational research : the journal of laboratory and clinical medicine, 2010, Volume: 156, Issue:6

    Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, A

2010
Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension.
    Cardiovascular research, 2011, Feb-15, Volume: 89, Issue:3

    Topics: Animals; Arginine; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Renal; Kidney

2011
Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice.
    Journal of the American College of Cardiology, 2011, Feb-08, Volume: 57, Issue:6

    Topics: Animals; Arrhythmogenic Right Ventricular Dysplasia; Cardiac Volume; Connexin 43; Disease Models, An

2011
Olive oil effectively mitigates ovariectomy-induced osteoporosis in rats.
    BMC complementary and alternative medicine, 2011, Feb-04, Volume: 11

    Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone Density; Bone Resorption; Calcium; Dietary Supplemen

2011
A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs.
    Experimental eye research, 2011, Volume: 93, Issue:3

    Topics: Amides; Animals; Antihypertensive Agents; Aorta; Bimatoprost; Chromatography, High Pressure Liquid;

2011
Locomotor damage and brain oxidative stress induced by lead exposure are attenuated by gallic acid treatment.
    Toxicology letters, 2011, May-30, Volume: 203, Issue:1

    Topics: Animals; Antioxidants; Behavior, Animal; Brain; Catalase; Chelating Agents; Disease Models, Animal;

2011
Insights into the effect of nitric oxide and its metabolites nitrite and nitrate at inhibiting neointimal hyperplasia.
    Nitric oxide : biology and chemistry, 2011, Jun-30, Volume: 25, Issue:1

    Topics: Animals; Cell Proliferation; Cells, Cultured; Coronary Artery Disease; Disease Models, Animal; Hyper

2011
Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats.
    Experimental eye research, 2011, Volume: 93, Issue:4

    Topics: Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Electrophoresis, Polyacrylamide Ge

2011
Interplay of endothelial and inducible nitric oxide synthases modulates the vascular response to ischaemia-reperfusion in the rabbit lung.
    Acta physiologica (Oxford, England), 2012, Volume: 204, Issue:3

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Lung; NADPH Oxidases; Nitrates; Nitric Oxide; Ni

2012
Leukotriene synthesis inhibitor decreases vasopressin release in the early phase of sepsis.
    Journal of neuroimmunology, 2011, Sep-15, Volume: 238, Issue:1-2

    Topics: Animals; Cecum; Cell Movement; Disease Models, Animal; Enzyme Inhibitors; Hematocrit; Indoles; Leuko

2011
Reversal of cerebral vasospasm via intravenous sodium nitrite after subarachnoid hemorrhage in primates.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Animals; Cerebral Angiography; Disease Models, Animal; Infusions, Intravenous; Macaca fascicularis;

2011
Vascular contribution of adrenomedullin to microcirculatory improvement in experimental colitis.
    European journal of pharmacology, 2011, Nov-30, Volume: 670, Issue:2-3

    Topics: Adrenomedullin; Animals; Biomarkers; Colitis; Cyclooxygenase 2; Disease Models, Animal; Gene Express

2011
Staphylococcus aureus infection induced redox signaling and DNA fragmentation in T-lymphocytes: possible ameliorative role of nanoconjugated vancomycin.
    Toxicology mechanisms and methods, 2012, Volume: 22, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Apoptosis; Catalase; Chemistry, Pharmaceutical; Disease Models, Anim

2012
Melatonin ameliorates necrotizing enterocolitis in a neonatal rat model.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:11

    Topics: Animals; Animals, Newborn; Antioxidants; Cold Temperature; Disease Models, Animal; Drug Evaluation,

2011
Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB.
    International immunopharmacology, 2012, Volume: 12, Issue:1

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Lipopolysaccharides; M

2012
Subtotal nephrectomy plus coronary ligation leads to more pronounced damage in both organs than either nephrectomy or coronary ligation.
    American journal of physiology. Heart and circulatory physiology, 2012, Feb-01, Volume: 302, Issue:3

    Topics: Animals; Blood Pressure; Cardio-Renal Syndrome; Coronary Stenosis; Disease Models, Animal; Gene Expr

2012
(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death.
    Neurochemistry international, 2012, Volume: 60, Issue:2

    Topics: Animals; Benzofurans; Cell Death; Cinnamates; Disease Models, Animal; Hypoxia-Ischemia, Brain; Male;

2012
Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:5

    Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Cyclic GMP; Disease Models

2012
Diosmin, a bioflavonoid reverses alterations in blood pressure, nitric oxide, lipid peroxides and antioxidant status in DOCA-salt induced hypertensive rats.
    European journal of pharmacology, 2012, Mar-15, Volume: 679, Issue:1-3

    Topics: Animals; Antihypertensive Agents; Aorta; Ascorbic Acid; Blood Pressure; Body Weight; Desoxycorticost

2012
The protective effects of ozone therapy in a rat model of acetaminophen-induced liver injury.
    Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases;

2012
Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:5

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cytoprotection; Disease Models, Animal;

2012
Physiologic responses to severe hemorrhagic shock and the genesis of cardiovascular collapse: can irreversibility be anticipated?
    The Journal of surgical research, 2012, Volume: 178, Issue:1

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Catecholamines; Cytokines; Disease Models, Animal

2012
Cysteinyl leukotriene receptor antagonism alleviates renal injury induced by ischemia-reperfusion in rats.
    The Journal of surgical research, 2012, Volume: 178, Issue:1

    Topics: Animals; Disease Models, Animal; Indoles; Intercellular Adhesion Molecule-1; Kidney Diseases; Leukot

2012
Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase.
    Circulation, 2012, Jun-12, Volume: 125, Issue:23

    Topics: Allopurinol; Animal Feed; Animals; Antibiotics, Antineoplastic; Bleomycin; Cyclic GMP; Disease Model

2012
Phage-mediated acquisition of a type III secreted effector protein boosts growth of salmonella by nitrate respiration.
    mBio, 2012, Volume: 3, Issue:3

    Topics: Animals; Bacterial Proteins; Cattle; Colitis; Disease Models, Animal; Feces; Gastrointestinal Tract;

2012
Enhanced estradiol-induced vasorelaxation in aortas from type 2 diabetic mice may reflect a compensatory role of p38 MAPK-mediated eNOS activation.
    Pflugers Archiv : European journal of physiology, 2012, Volume: 464, Issue:2

    Topics: Animals; Aorta; Diabetes Mellitus, Type 2; Disease Models, Animal; Estradiol; Estrogens; Female; In

2012
The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat.
    Behavioural brain research, 2012, Dec-01, Volume: 235, Issue:2

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain; Corticosterone; Disease Models,

2012
Salmonella "sops" up a preferred electron receptor in the inflamed intestine.
    mBio, 2012, Volume: 3, Issue:4

    Topics: Animals; Bacterial Proteins; Colitis; Colon; Disease Models, Animal; Host-Pathogen Interactions; Mic

2012
Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:1

    Topics: Amniotic Fluid; Animals; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA

2013
Dietary nitrate supplementation improves revascularization in chronic ischemia.
    Circulation, 2012, Oct-16, Volume: 126, Issue:16

    Topics: Animal Feed; Animals; Bone Marrow Transplantation; Cell Movement; Chronic Disease; Cyclic GMP; Dieta

2012
New perspectives for natural antimicrobial peptides: application as antinflammatory drugs in a murine model.
    BMC immunology, 2012, Nov-17, Volume: 13

    Topics: Administration, Intravenous; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Anti-Infective Age

2012
Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonary hypertension.
    Free radical biology & medicine, 2013, Volume: 56

    Topics: Animals; Bosentan; Disease Models, Animal; Female; Hypertension, Pulmonary; Nitrates; Nitrosation; O

2013
Downregulation of oxidative and nitrosative apoptotic signaling by L-carnitine in Ifosfamide-induced Fanconi syndrome rat model.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Apoptosis; Blood Urea Nitrogen; Carnitine; Caspases; Catalase; Creatinine; Disease Models,

2012
[The effect of nitrates on the outcome of acute experimental ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:12 Pt 2

    Topics: Animals; Disease Models, Animal; Magnesium Compounds; Male; Neuroprotective Agents; Nitrates; Potass

2012
Endothelial NOS (NOS3) impairs myocardial function in developing sepsis.
    Basic research in cardiology, 2013, Volume: 108, Issue:2

    Topics: Animals; Arterial Pressure; Cardiac Output; Cardiomyopathies; Coronary Circulation; Disease Models,

2013
Effect of morphine on the reduced uteroplacental perfusion model of pre-eclampsia in rats.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 168, Issue:2

    Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme Inhibitors; Female; Fetal Developme

2013
[Protective effect of Ginkgo biloba extract on acute lung injury induced by lipopolysaccharide in D-galactose aging rats].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2002, Volume: 25, Issue:6

    Topics: Aging; Animals; Disease Models, Animal; Endothelin-1; Galactose; Ginkgo biloba; Lipopolysaccharides;

2002
Mice expressing the alpha(1B)-adrenergic receptor induces a synucleinopathy with excessive tyrosine nitration but decreased phosphorylation.
    Journal of neurochemistry, 2002, Volume: 83, Issue:3

    Topics: Adrenergic alpha-Antagonists; alpha-Synuclein; Animals; Body Weight; Brain; Cerebellum; Disease Mode

2002
Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myocardial infarction.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5

    Topics: Adenoviridae; Animals; Apoptosis; Cell Survival; Disease Models, Animal; Dobutamine; Gene Transfer T

2002
Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:6

    Topics: Animals; Cytokines; Disease Models, Animal; Isotonic Solutions; Lactic Acid; Lipopolysaccharides; Ma

2002
L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice.
    European journal of pharmacology, 2002, Dec-20, Volume: 457, Issue:2-3

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Brain Ischemia; Disease Models, Animal; Enzyme

2002
Cyclooxygenase-2 inhibition attenuates lipopolysaccharide-induced cardiovascular failure.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Animals; Blood Pressure; Cardiovascular Diseases; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2002
Effects of nebulized diethylenetetraamine-NONOate in a mouse model of acute Pseudomonas aeruginosa pneumonia.
    Chest, 2002, Volume: 122, Issue:6

    Topics: Acute Disease; Aerosols; Animals; Disease Models, Animal; Hydrazines; Lung; Male; Mice; Mice, Inbred

2002
Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.
    Molecular medicine (Cambridge, Mass.), 2002, Volume: 8, Issue:10

    Topics: Animals; Catalysis; Cytoprotection; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Re

2002
Effect of NOS2 gene deficiency on the development of autoantibody mediated arthritis and subsequent articular cartilage degeneration.
    The Journal of rheumatology, 2003, Volume: 30, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Arthritis, Experimental; Autoantibodies; Cartilage, Articular; Chon

2003
Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure.
    Nitric oxide : biology and chemistry, 2003, Volume: 8, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Creatine; Dietary Supplements; Disease Models, Animal; Glomerulos

2003
Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats.
    Intensive care medicine, 2003, Volume: 29, Issue:2

    Topics: Acidosis, Lactic; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Gas Analysis; Diseas

2003
The inducible nitric oxide synthase inhibitor BBS-2 prevents acute lung injury in sheep after burn and smoke inhalation injury.
    American journal of respiratory and critical care medicine, 2003, Apr-01, Volume: 167, Issue:7

    Topics: Animals; Blood Pressure; Body Surface Area; Burns; Disease Models, Animal; Enzyme Inhibitors; Extrav

2003
The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; Cecum; Disease Models, Animal; Intestinal Perforation; Ligation;

2003
Postnatal changes in the nitric oxide system of the rat cerebral cortex after hypoxia during delivery.
    Brain research. Developmental brain research, 2003, May-14, Volume: 142, Issue:2

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cell Differentiation; Cerebral Cortex; Cerebrovascul

2003
Nicotinamide increases systemic vascular resistance in ovine endotoxemia.
    Intensive care medicine, 2003, Volume: 29, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Disease Mode

2003
Effect of round window membrane application of nitric oxide on hearing and nitric oxide concentration in perilymph.
    International journal of pediatric otorhinolaryngology, 2003, Volume: 67, Issue:6

    Topics: Animals; Chinchilla; Cochlea; Disease Models, Animal; Female; Hearing; Hearing Loss; Hearing Tests;

2003
Altered insulin-like growth factor-1 and nitric oxide sensitivities in hypertension contribute to vascular hyperplasia.
    American journal of hypertension, 2003, Volume: 16, Issue:5 Pt 1

    Topics: Animals; Aorta, Thoracic; Biomarkers; Blood Pressure; Cell Count; Cell Survival; Cyclic GMP; Diastol

2003
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.
    Journal of neurochemistry, 2003, Volume: 85, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Dise

2003
Species-specific modulation of the nitric oxide pathway after acute experimentally induced endotoxemia.
    Critical care medicine, 2003, Volume: 31, Issue:5

    Topics: Amidines; Animals; Benzylamines; Blood Pressure; Breath Tests; Disease Models, Animal; Drug Evaluati

2003
The role of inducible nitric oxide synthase inhibitor on the arteriolar hyporesponsiveness in hemorrhagic-shocked rats.
    Life sciences, 2003, Aug-22, Volume: 73, Issue:14

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors;

2003
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2003, Volume: 9, Issue:3

    Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Func

2003
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.
    Circulation, 2003, Sep-23, Volume: 108, Issue:12

    Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzy

2003
Nitric oxide system and protein nitration are modified by an acute hypobaric hypoxia in the adult rat hippocampus.
    Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:8

    Topics: Animals; Blotting, Western; Cell Count; Disease Models, Animal; Endothelium, Vascular; Glial Fibrill

2003
Alternative splicing of cGMP-dependent protein kinase I in angiotensin-hypertension: novel mechanism for nitrate tolerance in vascular smooth muscle.
    Circulation research, 2003, Oct-31, Volume: 93, Issue:9

    Topics: Alternative Splicing; Angiotensins; Animals; Blood Pressure; Cell Separation; Cyclic GMP; Cyclic GMP

2003
Anticaries efficacy of a new dentifrice for hypersensitivity.
    American journal of dentistry, 2003, Volume: 16, Issue:4

    Topics: Acid Etching, Dental; Actinomyces viscosus; Animals; Biological Availability; Cariostatic Agents; De

2003
Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia.
    Circulation, 2003, Dec-02, Volume: 108, Issue:22

    Topics: Animals; Antioxidants; Blood Vessels; Carotid Arteries; Cyclic GMP; Cyclic GMP-Dependent Protein Kin

2003
A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: Acetates; Amines; Animals; Aorta, Thoracic; Behavior, Animal; Cyclic GMP; Cyclohexanecarboxylic Acid

2004
A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Cardiomyopathy, Dilated; Cricetinae; Cytos

2004
Effects of L-arginine and NG-nitro L-arginine methyl ester on lipid peroxide, superoxide dismutase and nitrate levels after experimental sciatic nerve ischemia-reperfusion in rats.
    The International journal of neuroscience, 2004, Volume: 114, Issue:3

    Topics: Animals; Arginine; Disease Models, Animal; Female; Histological Techniques; Laparotomy; Lipid Peroxi

2004
Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation.
    British journal of pharmacology, 2004, Volume: 141, Issue:6

    Topics: Animals; Carrageenan; Disease Models, Animal; Enzyme Inhibitors; Intercellular Adhesion Molecule-1;

2004
Additional evidence of acute anti-inflammatory effects of cyclosporin A in a murine model of pleurisy.
    Transplant immunology, 2004, Volume: 12, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chemotaxis, Leukocyte; Cyclosporine; Disease Models,

2004
Spermine reduces infarction and neurological deficit following a rat model of middle cerebral artery occlusion: a magnetic resonance imaging study.
    Neuroscience, 2004, Volume: 124, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Brain Infarction; Brain Mapping; D

2004
Antioxidant enzyme activity and mRNA expression in the islets of Langerhans from the BB/S rat model of type 1 diabetes and an insulin-producing cell line.
    Journal of molecular medicine (Berlin, Germany), 2004, Volume: 82, Issue:5

    Topics: Animals; Antioxidants; Catalase; Cell Line; Cytokines; Diabetes Mellitus, Type 1; Disease Models, An

2004
Neutrophil and platelet dynamics at organ level after cardiopulmonary bypass: an in vivo study in neonatal pigs.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2004, Volume: 112, Issue:2

    Topics: Animals; Animals, Newborn; Blood Platelets; Cardiopulmonary Bypass; Disease Models, Animal; Gamma Ca

2004
Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation.
    The Journal of physiology, 2004, Jun-01, Volume: 557, Issue:Pt 2

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Body Weigh

2004
Effects of triflusal on oxidative stress, prostaglandin production and nitric oxide pathway in a model of anoxia-reoxygenation in rat brain slices.
    Brain research, 2004, Jun-18, Volume: 1011, Issue:2

    Topics: Analysis of Variance; Animals; Aspirin; Disease Models, Animal; Dose-Response Relationship, Drug; Gl

2004
Sequential changes in redox status and nitric oxide synthases expression in the liver after bile duct ligation.
    Life sciences, 2004, Jun-25, Volume: 75, Issue:6

    Topics: Animals; Bile Ducts, Extrahepatic; Blood Pressure; Blotting, Western; Disease Models, Animal; Hydrox

2004
Sleep-wake architecture in mouse models for Down syndrome.
    Neurobiology of disease, 2004, Volume: 16, Issue:2

    Topics: Animals; Brain Stem; Cerebral Cortex; Disease Models, Animal; Down Syndrome; Mice; Mice, Transgenic;

2004
Oral administration of Crataegus flavonoids protects against ischemia/reperfusion brain damage in gerbils.
    Journal of neurochemistry, 2004, Volume: 90, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Brain Chemistry; Cell Nucleus; Crataegus; Disease Model

2004
Involvement of steroids in anti-inflammatory effects of PK11195 in a murine model of pleurisy.
    Mediators of inflammation, 2004, Volume: 13, Issue:2

    Topics: Adenosine Deaminase; Aminoglutethimide; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Ca

2004
Upregulation of endothelial nitric oxide synthase maintains nitric oxide production in the cerebellum of thioacetamide cirrhotic rats.
    Neuroscience, 2004, Volume: 126, Issue:4

    Topics: Animals; Blotting, Western; Cerebellum; Disease Models, Animal; Gene Expression Regulation, Enzymolo

2004
Nuclear factor-kappaB regulates inflammatory cell apoptosis and phagocytosis in rat carrageenin-sponge implant model.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Animals; Apoptosis; Blotting, Western; Carrageenan; Cell Movement; Disease Models, Animal; Enzyme-Li

2004
Effects of aminoguanidine and L-arginine methyl ester resuscitation following induction of fluid-percussion injury and severe controlled hemorrhagic shock in the rat brain.
    Journal of neurosurgery, 2004, Volume: 101, Issue:1

    Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal;

2004
Future Pain Drugs - Europe 2003. 15-16 September 2003, London, UK.
    IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:11

    Topics: Acetaminophen; Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, A

2003
Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: Agmatine; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Brain Infarction; Cell

2004
NCX-701. NicOx.
    Current opinion in investigational drugs (London, England : 2000), 2004, Volume: 5, Issue:7

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Clinical T

2004
Denitrification genes regulate Brucella virulence in mice.
    Journal of bacteriology, 2004, Volume: 186, Issue:18

    Topics: Adaptation, Physiological; Agrobacterium tumefaciens; Animals; Anion Transport Proteins; Artificial

2004
Protective effects of the Chinese prescription Hachimi-jio-gan against diabetic oxidative stress.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:10

    Topics: Animals; Blood Glucose; Blood Proteins; Creatinine; Diabetes Mellitus, Experimental; Disease Models,

2004
Inhibitory effects of proanthocyanidins from Ribes nigrum leaves on carrageenin acute inflammatory reactions induced in rats.
    BMC pharmacology, 2004, Oct-21, Volume: 4

    Topics: Animals; Carrageenan; Cytokines; Disease Models, Animal; Edema; Inflammation; Male; Nitrates; Nitrit

2004
The effects of hyaluronan on bone resorption and bone mineral density in a rat model of estrogen deficiency-induced osteopenia.
    International journal of tissue reactions, 2004, Volume: 26, Issue:1-2

    Topics: Amino Acids; Animals; Body Weight; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Disease

2004
The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats.
    American journal of hypertension, 2004, Volume: 17, Issue:12 Pt 1

    Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Blotting, Western; Disease Mode

2004
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis.
    The Journal of biological chemistry, 2005, Apr-22, Volume: 280, Issue:16

    Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Mice; Mice,

2005
Local and systemic expression of inducible nitric oxide synthase in comparison with that of cyclooxygenase-2 in rat carrageenin-induced pleurisy.
    Nitric oxide : biology and chemistry, 2005, Volume: 12, Issue:2

    Topics: Animals; Carrageenan; Cell Count; Cyclooxygenase 2; Disease Models, Animal; Immunohistochemistry; Le

2005
[Role of nitric oxide and lipid peroxidation in pathogenesis of acute experimental pancreatitis].
    Klinichna khirurhiia, 2005, Issue:1

    Topics: Animals; Arginine; Disease Models, Animal; Lipid Peroxidation; Lipid Peroxides; Male; Methylene Blue

2005
Effects of chronic quercetin treatment in experimental renovascular hypertension.
    Molecular and cellular biochemistry, 2005, Volume: 270, Issue:1-2

    Topics: Animals; Antioxidants; Aorta; Blood Pressure; Body Weight; Diet; Disease Models, Animal; Dose-Respon

2005
Relationship between iNOS expression and aortic cell proliferation and apoptosis in an elastase-induced model of aorta aneurysm and the effect of 1400 W administration.
    Surgery, 2005, Volume: 137, Issue:4

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Cell Division; Disease Models, Ani

2005
Development and validation of a novel IL-10 deficient cell transfer model for colitis.
    International immunopharmacology, 2005, Volume: 5, Issue:6

    Topics: Adrenal Cortex Hormones; Animals; Antibodies, Monoclonal; Cell Transplantation; Disease Models, Anim

2005
[Decrease of nitric oxide (NO)-cGMP-dependent vasodilatation in the vessels of lesser circulation in endothelial dysfunction].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2005, Volume: 91, Issue:2

    Topics: Animals; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; H

2005
The anti-inflammatory effect of inhaled nitric oxide on pulmonary inflammation in a swine model.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:3

    Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Apoptosis; Bronchoalveolar Lavage Flu

2005
Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:3

    Topics: Animals; Cell Cycle Proteins; Cell Division; Cyclic GMP; Cyclin-Dependent Kinase Inhibitor p27; Deso

2005
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
    Journal of hypertension, 2005, Volume: 23, Issue:7

    Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Dis

2005
The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:10

    Topics: Animals; Brain; Central Nervous System; CREB-Binding Protein; Cytochrome P-450 Enzyme System; Diseas

2005
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Disease Models, Animal; Drug Administration Sch

2006
Meningoencephalitic African trypanosomiasis: Brain IL-10 and IL-6 are associated with protection from neuro-inflammatory pathology.
    Journal of neuroimmunology, 2005, Volume: 167, Issue:1-2

    Topics: Animals; Brain; Central Nervous System Viral Diseases; Cytokines; Disease Models, Animal; Encephalit

2005
Ibuprofen reduces plasma nitrite/nitrate levels in a rabbit model of endotoxin-induced shock.
    Neuro endocrinology letters, 2005, Volume: 26, Issue:4

    Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypotension; Ibuprofen;

2005
In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model.
    Biochemical pharmacology, 2005, Oct-15, Volume: 70, Issue:8

    Topics: Animals; Base Sequence; Chlamydia Infections; Chlamydophila pneumoniae; Disease Models, Animal; DNA

2005
Arterial hypoxemia and intrapulmonary vasodilatation in rat models of portal hypertension.
    Journal of gastroenterology, 2005, Volume: 40, Issue:8

    Topics: Animals; Arteries; Disease Models, Animal; Endothelin-1; Hepatopulmonary Syndrome; Hypertension, Por

2005
Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia.
    Critical care medicine, 2005, Volume: 33, Issue:9

    Topics: Acidosis; Animals; Blood Pressure; Disease Models, Animal; Diuresis; Endotoxemia; Hemodynamics; Lipi

2005
Pulmonary and systemic nitric oxide metabolites in a baboon model of neonatal chronic lung disease.
    American journal of respiratory cell and molecular biology, 2005, Volume: 33, Issue:6

    Topics: Administration, Inhalation; Animals; Animals, Newborn; Chronic Disease; Cysteine; Disease Models, An

2005
DSS-induced colitis is exacerbated in STAT-6 knockout mice.
    Inflammatory bowel diseases, 2005, Volume: 11, Issue:10

    Topics: Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Interferon-gamma; Mice; Mice, Inbred BALB

2005
A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:11

    Topics: Animals; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; In Vitro

2005
Nitrosative stress in an animal model of necrotizing enterocolitis.
    Free radical biology & medicine, 2005, Dec-01, Volume: 39, Issue:11

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Hypoxia; Ileu

2005
Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-22, Volume: 102, Issue:47

    Topics: Animals; Antioxidants; Arginine; Bone Marrow Transplantation; Disease Models, Animal; Fluorescent An

2005
Possible role of nitric oxide in the protective effect of resveratrol in 5/6th nephrectomized rats.
    The Journal of surgical research, 2006, Jun-15, Volume: 133, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Pressure; Body Weight; Disease Models, Animal; Eat

2006
Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis.
    Experimental neurology, 2006, Volume: 197, Issue:2

    Topics: Adrenomedullin; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; B

2006
Salutary effects of estrogen receptor-beta agonist on lung injury after trauma-hemorrhage.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:5

    Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Estradiol; Estr

2006
Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Animals; Arginine; Behavior, Animal; Cold Temperature; Constriction, Pathologic; Disease Models, Ani

2006
Hemodynamic effects of sildenafil interaction with a nitric oxide donor compound in a dog model of acute pulmonary embolism.
    Life sciences, 2006, Jun-27, Volume: 79, Issue:5

    Topics: Animals; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dogs; Drug Interactions; Female; Heart

2006
Cognitive deficits in rats after forebrain cholinergic depletion are reversed by a novel NO mimetic nitrate ester.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:3

    Topics: Acetylcholine; Analysis of Variance; Animals; Behavior, Animal; Choice Behavior; Cognition Disorders

2007
Endothelially derived nitric oxide affects the severity of early acetaminophen-induced hepatic injury in mice.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2006, Volume: 13, Issue:5

    Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Disease Models

2006
Respiratory syncytial virus infection in a murine model of cystic fibrosis.
    Journal of medical virology, 2006, Volume: 78, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Inflammation; Lung; Lymph

2006
Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats.
    World journal of gastroenterology, 2006, Mar-28, Volume: 12, Issue:12

    Topics: Acetylcysteine; Administration, Oral; Animals; Disease Models, Animal; Fatty Liver; Lipid Peroxidati

2006
Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats.
    Thrombosis and haemostasis, 2006, Volume: 95, Issue:6

    Topics: Animals; Antithrombins; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Calciton

2006
Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome.
    Nitric oxide : biology and chemistry, 2006, Volume: 15, Issue:4

    Topics: Animals; Biomarkers; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Chromatography,

2006
Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis.
    Critical care medicine, 2006, Volume: 34, Issue:9

    Topics: Airway Obstruction; Animals; Blood Pressure; Body Temperature; Disease Models, Animal; Female; Fibri

2006
Regulation of fibrogenesis during the early phase of common bile duct obstruction.
    ANZ journal of surgery, 2006, Volume: 76, Issue:7

    Topics: Animals; Cell Proliferation; Cholestasis; Collagen; Common Bile Duct Diseases; Dinoprostone; Disease

2006
Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:5

    Topics: Analysis of Variance; Animals; Atorvastatin; Biomarkers; Blood Pressure; Body Weight; Dexamethasone;

2006
Blockade of endothelin ET(A)/ET(B) receptors favors a role for endothelin during acute Trypanosoma cruzi infection in rats.
    Microbes and infection, 2006, Volume: 8, Issue:8

    Topics: Animal Structures; Animals; Bosentan; Chagas Disease; Chemokines; Cytokines; Diaphragm; Disease Mode

2006
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:8

    Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Disease Models, Animal; Energy Metaboli

2006
Effect of a nitric oxide releasing derivative of paracetamol in a rat model of endotoxaemia.
    British journal of pharmacology, 2006, Volume: 149, Issue:5

    Topics: Acetaminophen; Acetylcholine; Animals; Aspartate Aminotransferases; Blood Pressure; Creatinine; Cycl

2006
The effect of substance P on nitric oxide release in a rheumatoid arthritis model.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2006, Volume: 55, Issue:6

    Topics: Aged; Animals; Arthritis, Rheumatoid; Cells, Cultured; Disease Models, Animal; Female; Gene Expressi

2006
Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice.
    The Journal of pathology, 2006, Volume: 210, Issue:3

    Topics: Animals; Biomarkers; Disease Models, Animal; Electrodes; Female; Granuloma; Hypoxia; Immunohistochem

2006
Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep.
    Shock (Augusta, Ga.), 2006, Volume: 26, Issue:5

    Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Lung; Microcirculation; Multipl

2006
Systemic and regional hemodynamics in pigs with acute liver failure and the effect of albumin dialysis.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:11

    Topics: Albumins; Algorithms; Analysis of Variance; Animals; Blood Pressure; Catecholamines; Creatinine; Dis

2006
Methylprednisolone increases urinary nitrate concentrations and reduces subclinical renal injury during infrarenal aortic ischemia reperfusion.
    Annals of surgery, 2006, Volume: 244, Issue:5

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Aorta, Abdominal; Biomarkers; Disease Models, A

2006
Enhanced NTPDase and 5'-nucleotidase activities in diabetes mellitus and iron-overload model.
    Molecular and cellular biochemistry, 2007, Volume: 298, Issue:1-2

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adult; Animals; Antigens, CD; Apyrase; Blood Glucose; Blood Pl

2007
Flurbiprofen and its nitric oxide-releasing derivative protect against septic shock in rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2006, Volume: 55, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cecum; Disease Models, Animal; Flu

2006
Effect of sex hormones on non-esterified fatty acids, intra-abdominal fat accumulation, and hypertension induced by sucrose diet in male rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:8

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Dietary Sucrose; Disease Models, Animal; Estrad

2006
Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9.
    Critical care medicine, 2007, Volume: 35, Issue:1

    Topics: Acute Disease; Analysis of Variance; Animals; Atorvastatin; Disease Models, Animal; Drug Evaluation,

2007
Nitric oxide modulates glutathione synthesis during endotoxemia.
    Free radical biology & medicine, 2006, Dec-15, Volume: 41, Issue:12

    Topics: Animals; Body Weight; Catalase; Cysteine; Disease Models, Animal; Eating; Endotoxemia; Glutamate-Cys

2006
Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage.
    Journal of neurotrauma, 2006, Volume: 23, Issue:12

    Topics: Animals; Benzenesulfonates; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Male; Nitrates

2006
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:2

    Topics: Animals; Disease Models, Animal; Kidney; Male; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide

2007
Sex differences in modulating blood brain barrier permeability by NO in pentylenetetrazol-induced epileptic seizures.
    Life sciences, 2007, Mar-13, Volume: 80, Issue:14

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Convulsants; Disease Models, Animal; Dr

2007
Carnitine deficiency provokes cisplatin-induced hepatotoxicity in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:3

    Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti

2007
Effects of MnSOD-plasmid liposome gene therapy on antioxidant levels in irradiated murine oral cavity orthotopic tumors.
    Radiation research, 2007, Volume: 167, Issue:3

    Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Genetic Therapy; Hyd

2007
Inhibition of corneal angiogenesis by ascorbic acid in the rat model.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2007, Volume: 245, Issue:10

    Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Antioxidants; Ascorbic Acid; Corneal Neov

2007
Antagonic effect of the inhibition of inducible nitric oxide on the mortality of mice acutely infected with Escherichia coli and Bacteroides fragilis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:3

    Topics: Acute Disease; Animals; Bacteroides fragilis; Bacteroides Infections; Disease Models, Animal; Escher

2007
In which period of injury is resveratrol treatment effective: ischemia or reperfusion?
    Annals of vascular surgery, 2007, Volume: 21, Issue:3

    Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; H

2007
Ceftazidime improves hemodynamics and oxygenation in ovine smoke inhalation injury and septic shock.
    Intensive care medicine, 2007, Volume: 33, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Blood Pressure; Ceftazidime; Disease Models, Animal; Female; Heart R

2007
High-density lipoprotein prevents organ damage in endotoxemia.
    Research in nursing & health, 2007, Volume: 30, Issue:3

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Blood Pressure; Bl

2007
Endotoxemia produces coma and brain swelling in bile duct ligated rats.
    Hepatology (Baltimore, Md.), 2007, Volume: 45, Issue:6

    Topics: Ammonia; Animals; Brain; Brain Edema; Capillaries; Cholestasis, Extrahepatic; Coma; Consciousness; C

2007
Nitrate sensing and metabolism modulate motility, biofilm formation, and virulence in Pseudomonas aeruginosa.
    Infection and immunity, 2007, Volume: 75, Issue:8

    Topics: Animals; Bacterial Proteins; Biofilms; Caenorhabditis elegans; Disease Models, Animal; DNA-Binding P

2007
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Jan-21, Volume: 52 Suppl

    Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inh

2007
The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:3

    Topics: Animals; Blood Pressure; Catechin; Disease Models, Animal; Gene Expression; Lung; Male; Mice; Mice,

2007
Pyrrolidine dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model.
    World journal of surgery, 2007, Volume: 31, Issue:8

    Topics: Animals; Antioxidants; Capillary Permeability; Disease Models, Animal; Glutathione; Lung; Malondiald

2007
Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat.
    European journal of pharmacology, 2007, Aug-13, Volume: 569, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Diclofenac; Dinoprostone; Disease Mod

2007
Simvastatin for rats with thioacetamide-induced liver failure and encephalopathy.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:7 Pt 2

    Topics: Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Disease Models, Anim

2008
[Influence of polycythaemia on erythrodieresis].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:3

    Topics: Animals; Cell Communication; Cells, Cultured; Disease Models, Animal; Erythrocytes; Female; Macropha

2007
Acute systemic inflammation induces central mitochondrial damage and mnesic deficit in adult Swiss mice.
    Neuroscience letters, 2007, Sep-07, Volume: 424, Issue:2

    Topics: Animals; Behavior, Animal; Cognition Disorders; Cyclooxygenase 2; Disease Models, Animal; Glutathion

2007
A moderately high fat diet promotes salt-sensitive hypertension in obese zucker rats by impairing nitric oxide production.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2007, Volume: 29, Issue:6

    Topics: Animals; Body Weight; Diet; Dietary Fats; Disease Models, Animal; Feedback, Physiological; Female; H

2007
Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard.
    Toxicology letters, 2007, Sep-10, Volume: 173, Issue:2

    Topics: Animals; Antioxidants; Biomarkers; Chemical Warfare Agents; Disease Models, Animal; Dose-Response Re

2007
Enteral resveratrol supplementation attenuates intestinal epithelial inducible nitric oxide synthase activity and mucosal damage in experimental necrotizing enterocolitis.
    Journal of pediatric surgery, 2007, Volume: 42, Issue:10

    Topics: Administration, Oral; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Drug Evaluati

2007
Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:1

    Topics: Animals; Anion Transport Proteins; Antioxidants; CHO Cells; Cricetinae; Cricetulus; Deafness; Diseas

2008
Corneal protein nitration in experimental uveitis.
    Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:10

    Topics: Animals; Disease Models, Animal; Eye Proteins; Immunohistochemistry; Male; Neutrophils; Nitrates; Ni

2007
Kynurenic acid inhibits intestinal hypermotility and xanthine oxidase activity during experimental colon obstruction in dogs.
    Neurogastroenterology and motility, 2008, Volume: 20, Issue:1

    Topics: Animals; Colonic Pseudo-Obstruction; Disease Models, Animal; Dogs; Gastrointestinal Motility; Hemody

2008
Investigation of neuroprotective effect of dexamethasone by using nitric oxide and leukocyte levels in experimental head trauma.
    The International journal of neuroscience, 2007, Volume: 117, Issue:12

    Topics: Animals; Craniocerebral Trauma; Dexamethasone; Disease Models, Animal; Leukocytes; Male; Neuroprotec

2007
The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.
    The Journal of surgical research, 2008, May-15, Volume: 146, Issue:2

    Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines;

2008
Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Animals; Colitis; Cyclic GMP; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Guanylate

2008
Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2

    Topics: Animals; Body Weight; Chemokine CCL2; Dinoprost; Disease Models, Animal; Eating; Free Radical Scaven

2008
Nitric oxide bioavailability and not production is first altered during the onset of insulin resistance in sucrose-fed rats.
    Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:11

    Topics: Animals; Aorta; Biomarkers; Cyclic GMP; Cysteine; Diet; Diet Therapy; Disease Models, Animal; Enzyme

2007
Renal functional responses to ischaemia-reperfusion injury in normotensive and hypertensive rats following non-selective and selective cyclo-oxygenase inhibition with nitric oxide donation.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Animals; Aspirin; Blood Pressure; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 In

2008
The effect of lipoic acid on antioxidant status and lipid peroxidation in rats exposed to chronic restraint stress.
    Physiological research, 2008, Volume: 57, Issue:6

    Topics: Animals; Antioxidants; Brain; Catalase; Disease Models, Animal; Glutathione Peroxidase; Lipid Peroxi

2008
How DMSO, a widely used solvent, affects spinal cord injury.
    Annals of vascular surgery, 2008, Volume: 22, Issue:1

    Topics: Animals; Aorta, Abdominal; Dimethyl Sulfoxide; Disease Models, Animal; Free Radical Scavengers; Liga

2008
Pharmacological induction of heme oxygenase-1 inhibits iNOS and oxidative stress in renal ischemia-reperfusion injury.
    Transplantation proceedings, 2007, Volume: 39, Issue:10

    Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Induction; Heme Oxygenase-1; Isoe

2007
Human umbilical cord blood-derived CD34+ cells can be used as a prophylactic agent for experimental heatstroke.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Animals; Antigens, CD34; Basal Ganglia; Cerebrovascular Disorders; Cord Blood Stem Cell Transplantat

2008
Effects of melatonin on ischemic spinal cord injury caused by aortic cross clamping in rabbits.
    Current neurovascular research, 2008, Volume: 5, Issue:1

    Topics: Animals; Antioxidants; Aorta, Abdominal; Constriction; Disease Models, Animal; Glutathione; Male; Ma

2008
Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: an indirect effect after praziquantel treatment.
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:4

    Topics: Animals; Cricetinae; Disease Models, Animal; Fishes; Male; Mesocricetus; Nitrates; Nitric Oxide Synt

2008
Beneficial effects of low doses of red wine consumption on perturbed shear stress-induced atherogenesis.
    Heart and vessels, 2008, Volume: 23, Issue:2

    Topics: Administration, Oral; Animals; Antioxidants; Atherosclerosis; Cells, Cultured; Disease Models, Anima

2008
Augmentation of vascular remodeling by uncoupled endothelial nitric oxide synthase in a mouse model of diabetes mellitus.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:6

    Topics: Animals; Aorta; Biopterins; Carotid Arteries; Cholesterol; Diabetes Mellitus, Experimental; Disease

2008
p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Abdomen; Animals; Calmodulin; Cardiotonic Agents; Caveolin 1; Chemokine CXCL1; Chemokine CXCL2; Dise

2008
Opioid receptor blockade improves mesenteric responsiveness in biliary cirrhosis.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:11

    Topics: Animals; Disease Models, Animal; Ligation; Liver Cirrhosis, Biliary; Male; Mesentery; Naltrexone; Na

2008
Nitrate and human cancer: a review of the evidence.
    International journal of epidemiology, 1980, Volume: 9, Issue:1

    Topics: Animals; Chile; Colombia; Diet; Disease Models, Animal; England; Fertilizers; Humans; Neoplasms; Nit

1980
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Nov-07, Volume: 92, Issue:23

    Topics: Animals; Base Sequence; Disease Models, Animal; Drug Resistance; Immunoblotting; Interferon-gamma; L

1995
Role of oxygen-derived metabolites in the rat gastric mucosal injury induced by nitric oxide donors.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Animals; Blood Pressure; Catalase; Deferoxamine; Disease Models, Animal; Drug Overdose; Drug Synergi

1995
Induction of nitric oxide synthase and concomitant suppression of superoxide dismutases in experimental colitis in rats.
    Archives of biochemistry and biophysics, 1995, Dec-01, Volume: 324, Issue:1

    Topics: Animals; Blotting, Northern; Colitis; Colon; Disease Models, Animal; Enzyme Induction; Female; Gene

1995
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Dise

1993
N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:7

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Male

1994
The pressor effect of recombinant human erythropoietin is not due to decreased activity of the endogenous nitric oxide system.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1995, Volume: 10, Issue:4

    Topics: Animals; Blood Pressure; Disease Models, Animal; Erythropoietin; Hematocrit; Hydrogen-Ion Concentrat

1995
Nitrovasodilators ITF 296 and isosorbide dinitrate exert antiischemic activity by dilating coronary penetrating arteries.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:5

    Topics: Analysis of Variance; Animals; Benzoxazines; Blood Pressure; Coronary Circulation; Coronary Disease;

1995
Increased endogenous N-nitrosamine and nitrate formation by induction of nitric oxide synthase in rats with acute hepatic injury caused by Propionibacterium acnes and lipopolysaccharide administration.
    Carcinogenesis, 1993, Volume: 14, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Disease Models, Animal; Enzyme Induction; Lipopolysaccharides;

1993
Spontaneous intestinal inflammation and nitric oxide metabolism in HLA-B27 transgenic rats.
    Gastroenterology, 1995, Volume: 109, Issue:1

    Topics: Animals; Animals, Genetically Modified; Colitis; Colon; Disease Models, Animal; Edetic Acid; Gastric

1995
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
    Chemico-biological interactions, 1995, Volume: 94, Issue:2

    Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA D

1995
The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence.
    Agents and actions, 1994, Volume: 41, Issue:1-2

    Topics: Administration, Inhalation; Animals; Arginine; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease

1994
Peroxynitrite-induced rat colitis--a new model of colonic inflammation.
    Gastroenterology, 1993, Volume: 105, Issue:6

    Topics: Animals; Colitis; Disease Models, Animal; Inflammatory Bowel Diseases; Intestinal Mucosa; Leukotrien

1993
The involvement of nitric oxide in a mouse model of adult respiratory distress syndrome.
    Inflammation, 1995, Volume: 19, Issue:5

    Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Dipeptides; Disease Models, Animal; Fe

1995
Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli.
    The Journal of clinical investigation, 1996, Jul-01, Volume: 98, Issue:1

    Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Free Radical Scaveng

1996
Pteridine and nitrite/nitrate formation in experimental septic and traumatic shock.
    Shock (Augusta, Ga.), 1996, Volume: 6, Issue:4

    Topics: Animals; Arteries; Cardiac Output; Creatinine; Disease Models, Animal; Escherichia coli Infections;

1996
Acute protein-calorie malnutrition impairs wound healing: a possible role of decreased wound nitric oxide synthesis.
    Journal of the American College of Surgeons, 1997, Volume: 184, Issue:1

    Topics: Acute Disease; Amino Acids; Animals; Cells, Cultured; Collagen; Disease Models, Animal; DNA; Hydroxy

1997
Formation of nitrosyl hemoglobin and nitrotyrosine during murine leishmaniasis.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:6

    Topics: Animals; Disease Models, Animal; Female; Hemoglobins; Leishmania mexicana; Leishmaniasis, Cutaneous;

1996
Nitric oxide synthase inhibitor influences prostaglandin and interleukin-1 production in experimental arthritic joints.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:2

    Topics: Animals; Arthritis, Experimental; Capillary Permeability; Chemotaxis, Leukocyte; Dinoprostone; Disea

1997
Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats.
    European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1

    Topics: Animals; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Injections, Intrav

1997
Peroxynitrite and oxidative damage in experimental autoimmune uveitis.
    Investigative ophthalmology & visual science, 1997, Volume: 38, Issue:7

    Topics: Animals; Arrestin; Autoimmune Diseases; Disease Models, Animal; Female; Fluorescent Antibody Techniq

1997
Protective effects of IL-4, IL-10, IL-12, and IL-13 in IgG immune complex-induced lung injury: role of endogenous IL-12.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Oct-01, Volume: 159, Issue:7

    Topics: Animals; Antigen-Antibody Complex; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Immunoglobu

1997
Inhibition of inducible nitric oxide synthase expression and stimulation of the endothelial formation of nitric oxide most likely accounts for the protective effect of 2-(allylthio)pyrazine in a murine model of endotoxemia.
    Biochemical and biophysical research communications, 1997, Oct-09, Volume: 239, Issue:1

    Topics: Animals; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Enzyme Inhibitors;

1997
Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of endotoxic shock.
    Biochemical and biophysical research communications, 1997, Nov-17, Volume: 240, Issue:2

    Topics: Adrenalectomy; Animals; Biopterins; Dexamethasone; Disease Models, Animal; Enzyme Induction; Escheri

1997
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
    Journal of pineal research, 1997, Volume: 23, Issue:2

    Topics: Animals; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema;

1997
Role of nitric oxide in experimental obliterative bronchiolitis (chronic rejection) in the rat.
    The Journal of clinical investigation, 1997, Dec-15, Volume: 100, Issue:12

    Topics: Animals; Bronchiolitis Obliterans; Cell Division; Cytokines; Disease Models, Animal; Graft Rejection

1997
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation.
    Free radical biology & medicine, 1998, Volume: 24, Issue:3

    Topics: Animals; Carrageenan; Disease Models, Animal; Edema; Enzyme Inhibitors; Free Radical Scavengers; Gua

1998
Selective iNOS inhibition is superior to norepinephrine in the treatment of rat endotoxic shock.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:1

    Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluati

1998
Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis.
    Kidney international, 1998, Volume: 53, Issue:2

    Topics: Animals; Anti-Glomerular Basement Membrane Disease; Cell Extracts; Disease Models, Animal; Hydrogen

1998
Regulatory interactions between inducible nitric oxide synthase and eicosanoids in glomerular immune injury.
    Kidney international, 1998, Volume: 53, Issue:3

    Topics: Animals; Base Sequence; Basement Membrane; Cyclooxygenase Inhibitors; Disease Models, Animal; DNA Pr

1998
Endotoxin-induced skeletal muscle contractile dysfunction: contribution of nitric oxide synthases.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Animals; Disease Models, Animal; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Skeletal; Ni

1998
Experimental focal segmental glomerulosclerosis in mice.
    Nephron, 1998, Volume: 78, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Cholesterol; Disease Models, Animal; Disease Progression; Doxo

1998
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
    The Journal of clinical investigation, 1998, May-15, Volume: 101, Issue:10

    Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart;

1998
Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:5

    Topics: Animals; Blood Pressure; Cell Nucleus; Death; Disease Models, Animal; DNA Damage; Male; Models, Biol

1998
Peroxynitrate-mediated DNA strand breakage activates poly(ADP-ribose) synthetase and causes cellular energy depletion in a nonseptic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:5

    Topics: Animals; Benzamides; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Activation; Macro

1998
Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension.
    Kidney international, 1998, Volume: 54, Issue:1

    Topics: Acetamides; Animals; Arginine; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonis

1998
Protective effect of ciliary neurotrophic factor (CNTF) in a model of endotoxic shock: action mechanisms and role of CNTF receptor alpha.
    Journal of inflammation, 1998, Volume: 48, Issue:2

    Topics: Adrenalectomy; Animals; Ciliary Neurotrophic Factor; Disease Models, Animal; Humans; Lipopolysacchar

1998
Klotho protein protects against endothelial dysfunction.
    Biochemical and biophysical research communications, 1998, Jul-20, Volume: 248, Issue:2

    Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Cardiovascular System; Disease Models, Animal; Endo

1998
Collagen induced arthritis: reversal by mercaptoethylguanidine, a novel antiinflammatory agent with a combined mechanism of action.
    The Journal of rheumatology, 1998, Volume: 25, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Collagen; Collagenases; Disease Models, Animal; Enzyme

1998
Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells.
    The Journal of clinical investigation, 1998, Sep-15, Volume: 102, Issue:6

    Topics: Amiloride; Animals; Biological Transport; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance

1998
Neuroprotection in selective focal ischemia in rats by nitrates, an alternative redox manipulation on nitric oxide: experimental model.
    Minimally invasive neurosurgery : MIN, 1998, Volume: 41, Issue:3

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Female; Hippocampus; Male; Neuroprotective Agents;

1998
Aerosolized soluble nitric oxide donor improves oxygenation and pulmonary hypertension in acute lung injury.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:5 Pt 1

    Topics: Administration, Inhalation; Aerosols; Amino Acids, Diamino; Animals; Cardiac Catheterization; Cardia

1998
Influence of L-arginine, aminoguanidine, and NG-nitro-L-arginine methyl ester (L-name) on the survival rate in a rat model of hemorrhagic shock.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:1

    Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Creatinine; Dinoprostone; Disease Mo

1999
Oral spermine administration inhibits nitric oxide-mediated intestinal damage and levels of systemic inflammatory mediators in a mouse endotoxin model.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:2

    Topics: Administration, Oral; Animals; Disease Models, Animal; Escherichia coli; Female; Immunohistochemistr

1999
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:2

    Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Respon

1999
Porcine endotoxemic shock is associated with increased expired nitric oxide.
    Critical care medicine, 1999, Volume: 27, Issue:2

    Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Mod

1999
Role of inducible nitric oxide synthase in leukocyte extravasation in vivo.
    Biochemical and biophysical research communications, 1999, Apr-21, Volume: 257, Issue:3

    Topics: Acute Disease; Animals; Ascitic Fluid; Blotting, Western; Cell Movement; Disease Models, Animal; Enz

1999
High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation.
    American journal of respiratory cell and molecular biology, 1999, Volume: 20, Issue:6

    Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Disease Models

1999
Vascular nitric oxide production during the development of two experimental models of portal hypertension.
    Journal of hepatology, 1999, Volume: 30, Issue:5

    Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Guanidines; Hypertension, Portal; In Vitro Techniq

1999
The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat.
    European journal of pharmacology, 1999, May-14, Volume: 372, Issue:2

    Topics: Animals; Carrageenan; Cells, Cultured; Disease Models, Animal; Free Radical Scavengers; Glutathione;

1999
Direct hyperplasia does not enhance the kinetics of liver repopulation in a new model of hepatocyte transplantation in the rat.
    Journal of hepatology, 1999, Volume: 31, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Transplantation; Dipeptidyl Peptidase 4; Disease Mo

1999
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Rad

1999
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Animals; Benzamides; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Multip

1999
Effects of cyanosis and hypothermic circulatory arrest on lung function in neonatal lambs.
    The Annals of thoracic surgery, 1999, Volume: 68, Issue:2

    Topics: Animals; Animals, Newborn; Cardiac Output; Cardiopulmonary Bypass; Chronic Disease; Cyanosis; Cyclic

1999
Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs.
    Intensive care medicine, 1999, Volume: 25, Issue:9

    Topics: Administration, Inhalation; Animals; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Emb

1999
Two patterns of lipid deposition in the cholesterol-fed rabbit.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:10

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Celiac Artery; Cholesterol, Dietary; Disease Models, Ani

1999
Diminished nitric oxide production following administration of transforming growth factor-beta1 using a noninflammatory wound repair model.
    Nitric oxide : biology and chemistry, 1999, Volume: 3, Issue:5

    Topics: Animals; Connective Tissue; Disease Models, Animal; Humans; Injections, Intraperitoneal; Male; Mesen

1999
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan.
    Shock (Augusta, Ga.), 1999, Volume: 12, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Kidne

1999
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage;

1999
Nuclear factor-kappaB activation mediates inducible nitric oxide synthase expression in carrageenin-induced rat pleurisy.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:6

    Topics: Animals; Antioxidants; Carrageenan; Cell Movement; Cell Nucleus; Disease Models, Animal; DNA; Dose-R

1999
Generation of peroxynitrite in localised, moderate temperature burns.
    Burns : journal of the International Society for Burn Injuries, 2000, Volume: 26, Issue:3

    Topics: Animals; Biomarkers; Burns; Culture Techniques; Disease Models, Animal; Enzyme-Linked Immunosorbent

2000
Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:5

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Disease Models, Animal; Encephalomyelitis, Autoimmune, Expe

2000
The role of intrarenal nitric oxide in the natriuretic response to dopamine-receptor activation.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:3

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dopamine; Dopamine Agonists; Enzyme Inhibitors;

2000
Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:9

    Topics: Animals; Blood Pressure; Catalysis; Celiac Artery; Disease Models, Animal; Endothelium, Vascular; Fe

2000
Pulmonary blast injury increases nitric oxide production, disturbs arginine metabolism, and alters the plasma free amino acid pool in rabbits during the early posttraumatic period.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:2

    Topics: Amino Acids; Animals; Arginine; Blast Injuries; Disease Models, Animal; Male; Nitrates; Nitric Oxide

2000
Role of nitric oxide in the failure of neutrophil migration in sepsis.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:1

    Topics: Animals; Ascitic Fluid; Bacteremia; Cell Movement; Colony Count, Microbial; Cytokines; Disease Model

2000
Differential regulation of nitric oxide synthase isoforms in experimental acute chagasic cardiomyopathy.
    Clinical and experimental immunology, 2000, Volume: 121, Issue:1

    Topics: Acute Disease; Animals; Chagas Cardiomyopathy; Disease Models, Animal; Isoenzymes; Male; Malondialde

2000
The effects of NO synthase inhibitors on murine collagen-induced arthritis do not support a role of NO in the protective effect of IFN-gamma.
    Journal of leukocyte biology, 2000, Volume: 68, Issue:1

    Topics: Administration, Oral; Animals; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Collagen;

2000
Increased urinary nitrate excretion associated with hepatic allograft rejection in experimental rat models and clinical cases.
    Transplant international : official journal of the European Society for Organ Transplantation, 2000, Volume: 13, Issue:4

    Topics: Animals; Child; Disease Models, Animal; Female; Graft Rejection; Humans; Immunosuppressive Agents; L

2000
Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid.
    Neuroscience letters, 2000, Oct-06, Volume: 292, Issue:2

    Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; F

2000
Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase.
    British journal of pharmacology, 2000, Volume: 131, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypertension;

2000
Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Aorta; Autoantibodies; Blood Pressure; Calcimycin; Cyclic GMP; Disease

2000
Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Blotting, Western; Cardiopulmonary Bypass; Cyclic GMP;

2000
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:12

    Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Dis

2000
Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis.
    Laboratory investigation; a journal of technical methods and pathology, 2000, Volume: 80, Issue:12

    Topics: Animals; Chronic Disease; Disease Models, Animal; Free Radicals; Hemosiderosis; Humans; Iron; Kidney

2000
Evaluation of low-dose endotoxin administration during pregnancy as a model of preeclampsia.
    Anesthesiology, 2000, Volume: 93, Issue:6

    Topics: Animals; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Dose-Response Relatio

2000
Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice.
    Brain research, 2001, Jan-12, Volume: 888, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Calcineurin; Calcium; Dantrolene; Disease Models, Animal; Dizocilpi

2001
Lipopolysaccharide binding protein potentiates airway reactivity in a murine model of allergic asthma.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Feb-01, Volume: 166, Issue:3

    Topics: Acute-Phase Proteins; Adjuvants, Immunologic; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperr

2001
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihyperten

2001
Inhibition of inducible nitric oxide synthase limits nitric oxide production and experimental aneurysm expansion.
    Journal of vascular surgery, 2001, Volume: 33, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression;

2001
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.
    Journal of neurochemistry, 2001, Volume: 76, Issue:6

    Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Ischemic Atta

2001
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:7

    Topics: Acetylcysteine; Animals; Blotting, Western; Carrageenan; Disease Models, Animal; DNA Damage; DNA-Bin

2001
Erythrocyte deformability is a nitric oxide-mediated factor in decreased capillary density during sepsis.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Acute Disease; Animals; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Electron Spin R

2001
Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Death; Colitis; Colon; Disease Models, Animal;

2001
Nitric oxide and Coxsackievirus B3 myocarditis: differential expression of inducible nitric oxide synthase in mouse heart after infection with virulent or attenuated virus.
    Journal of medical virology, 2001, Volume: 64, Issue:2

    Topics: Animals; Disease Models, Animal; Enterovirus; Guanosine Monophosphate; Heart; Immunohistochemistry;

2001
Cardiac functional and structural alterations induced by endotoxin in rats: importance of platelet-activating factor.
    Critical care medicine, 2001, Volume: 29, Issue:3

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Echocardiography; Electrocardiography

2001
In vitro and in vivo assessment of Salmonella enterica serovar Typhimurium DT104 virulence.
    Infection and immunity, 2001, Volume: 69, Issue:7

    Topics: Animals; Disease Models, Animal; Humans; Hydrogen Peroxide; Macrophages, Peritoneal; Mice; Mice, Inb

2001
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Animals; Arteries; Blood Flow Velocity; Blood Glucose; Body Weight; Disease Models, Animal; Glucose;

2001
Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats.
    International journal of cardiology, 2001, Volume: 79, Issue:2-3

    Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Cardiomyopathies; Disease Models, Animal; E

2001
The role of the interaction between endogenous opioids and nitric oxide in the pathophysiology of ethanol-induced gastric damage in cholestatic rats.
    Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:3

    Topics: Alcohol Deterrents; Animals; Arginine; Bile Ducts; Cholestasis; Disease Models, Animal; Enzyme Inhib

2001
Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation.
    Brain research, 2001, Aug-03, Volume: 909, Issue:1-2

    Topics: Animals; Blotting, Western; Cerebellum; Disease Models, Animal; Enzyme Inhibitors; Glucose; Hypoxia-

2001
N-acetyl-L-cysteine improves renal medullary hypoperfusion in acute renal failure.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Disease Models, Animal; Enzyme In

2001
Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
    Circulation research, 2001, Aug-17, Volume: 89, Issue:4

    Topics: Administration, Inhalation; Animals; Blotting, Western; Cells, Cultured; Dioxoles; Disease Models, A

2001
Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats.
    Circulation, 2001, Aug-21, Volume: 104, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cells, Cultured; Cyclin-Dependent

2001
Inhibition of nitric oxide synthesis by L-name exacerbates acute lung injury induced by hepatic ischemia-reperfusion.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:3

    Topics: Alanine Transaminase; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibito

2001
Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis.
    Circulation research, 2001, Aug-31, Volume: 89, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arteriosclerosis; Blood Pressure; Chemokine CCL2; Coronary Vessel

2001
Role of nitric oxide in acidosis-induced intestinal injury in anesthetized rats.
    The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:4

    Topics: Acidosis; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Hemodynamics;

2001
Presence of nitrotyrosine with minimal inducible nitric oxide synthase induction in lipopolysaccharide-treated pigs.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:4

    Topics: Animals; Blood Gas Analysis; Blotting, Western; Disease Models, Animal; Hemodynamics; Lipopolysaccha

2001
[Evidence of increased endogenous carbon monoxide production in asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1999, Volume: 22, Issue:4

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Cell Line; Child; Child, Preschool;

1999
Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily.
    Immunology letters, 2002, Mar-01, Volume: 80, Issue:3

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Cytokines; Disease Models, Anima

2002
Efficacy and age-related effects of nitric oxide-releasing aspirin on experimental restenosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Feb-05, Volume: 99, Issue:3

    Topics: Aging; Angioplasty, Balloon, Coronary; Animals; Aspirin; Coronary Restenosis; Coronary Vessels; Dise

2002
Inhibition of nitric oxide synthase does not influence urinary nitrite plus nitrate excretion after renal ischemic injury.
    Langenbeck's archives of surgery, 2002, Volume: 386, Issue:7

    Topics: Animals; Disease Models, Animal; Ischemia; Kidney; Kidney Tubules; Male; NG-Nitroarginine Methyl Est

2002
Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats.
    Blood, 2002, Mar-01, Volume: 99, Issue:5

    Topics: Animals; Antithrombin III; Disease Models, Animal; Endotoxins; Enzyme Induction; Epoprostenol; Human

2002
Detection of the gp43 gene and (1-3)-beta-D-glucan of Paracoccidioides brasiliensis in the blood of experimentally infected mice.
    Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology, 2002, Volume: 43, Issue:1

    Topics: Adult; Aged; Animals; Antigens, Fungal; beta-Glucans; Biomarkers; Child; Diphosphates; Disease Model

2002
Streptozotocin-pancreatic damage in the rat: modulatory effect of 15-deoxy delta12,14-prostaglandin j(2) on nitridergic and prostanoid pathway.
    Nitric oxide : biology and chemistry, 2002, Volume: 6, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Islets of Langerhans; Nitr

2002
[Expression of ET-1 mRNA in the lung of hepatopulmonary syndrome rats].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2002, Volume: 40, Issue:2

    Topics: Animals; Disease Models, Animal; Endothelin-1; Hepatopulmonary Syndrome; Image Processing, Computer-

2002
A synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Animals; Aorta; Cell Line; Disease Models, Animal; DNA; Drug Interactions; Fibrinolytic Agents; Gene

2002
Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Apoptosis; Disease Models, Animal; DNA; DNA

2002
Differential function of nitric oxide in murine antigen-induced arthritis.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:5

    Topics: Acute Disease; Animals; Arthritis, Experimental; Cell Adhesion Molecules; Chronic Disease; Disease M

2002
Cardiac response to nitric oxide synthase inhibition using aminoguanidine in a rat model of endotoxemia.
    Shock (Augusta, Ga.), 2002, Volume: 17, Issue:5

    Topics: Animals; Disease Models, Animal; Endotoxemia; Endotoxins; Enzyme Inhibitors; Guanidines; Heart; In V

2002
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:6

    Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus,

2002
Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1

    Topics: Animals; Blotting, Western; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Failu

2002
[Modified effect of lead on the embryotoxicity of cadmium].
    Gigiena i sanitariia, 1992, Issue:2

    Topics: Animals; Cadmium; Cadmium Chloride; Chlorides; Disease Models, Animal; Dose-Response Relationship, D

1992
A modified model of global ischaemia: application to the study of syncytial mechanisms of arrhythmogenesis.
    Cardiovascular research, 1992, Volume: 26, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Disease Models, Animal; Male; Myocardial Reperfusio

1992
Canine model of chronic bronchial injury. Lung mechanics and pathologic changes.
    The American review of respiratory disease, 1988, Volume: 137, Issue:2

    Topics: Animals; Bronchi; Bronchitis; Chronic Disease; Disease Models, Animal; Dogs; Histamine; Lung; Nitrat

1988
A canine model of bronchial injury induced by nitric acid. Lung mechanics and morphologic features.
    The American review of respiratory disease, 1986, Volume: 133, Issue:6

    Topics: Airway Resistance; Animals; Biomechanical Phenomena; Bronchial Diseases; Disease Models, Animal; Dog

1986
Experimental acute renal failure induced by uranyl nitrate in the dog.
    Circulation research, 1972, Volume: 31, Issue:5

    Topics: Acute Kidney Injury; Animals; Autoradiography; Blood Urea Nitrogen; Catheterization; Disease Models,

1972
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